LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 112

Search options

  1. Article ; Online: A liquid metal-based module emulating the intelligent preying logic of flytrap.

    Yang, Yuanyuan / Shen, Yajing

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 3398

    Abstract: Plant species like the Venus flytrap possess unique abilities to intelligently respond to various external stimuli, ensuring successful prey capture. Their nerve-devoided structure provides valuable insights for exploring natural intelligence and ... ...

    Abstract Plant species like the Venus flytrap possess unique abilities to intelligently respond to various external stimuli, ensuring successful prey capture. Their nerve-devoided structure provides valuable insights for exploring natural intelligence and constructing intelligent systems solely from materials, but limited knowledge is currently available and the engineering realization of such concept remains a significant challenge. Drawing upon the flytrap's action potential resulting from ion diffusion, we propose a signal accumulation/attenuation model and a corresponding liquid metal-based logic module, which operates on the basis of the shape change of liquid metal within a sodium hydroxide buffer solution. The module itself exhibits memory and counting properties without involving any other electronic components, intelligently responding to various stimulus sequences, and reproducing the flytrap's most logical function. We also demonstrate and forecast its potential as a moving window integration-based high-pass filter, artificial synapse in neural networks, and other related applications. This research provides a fresh perspective on comprehending the intelligence inherent in nature and its realization through physical structures, which is expected to inspire logic device development in a broad engineering field.
    Language English
    Publishing date 2024-04-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-47791-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Current emerging novel therapies for Alzheimer's disease and the future prospects of magneto-mechanical force therapy.

    Shen, Yajing / Wang, Meng / Li, Shutang / Yang, Jinfei

    Journal of materials chemistry. B

    2023  Volume 11, Issue 39, Page(s) 9404–9418

    Abstract: Alzheimer's disease (AD) is the most common neurodegenerative disease among the elderly, and the morbidity increases with the aging population aggravation. The clinical symptoms of AD mainly include cognitive impairment and memory loss, which undoubtedly ...

    Abstract Alzheimer's disease (AD) is the most common neurodegenerative disease among the elderly, and the morbidity increases with the aging population aggravation. The clinical symptoms of AD mainly include cognitive impairment and memory loss, which undoubtedly bring a huge burden to families and society. Currently, the drugs in clinical use only improve the symptoms of AD but do not cure or prevent the progression of the disease. Therefore, it is urgent for us to develop novel therapeutic strategies for effective AD treatment. To provide a better theoretical basis for exploring novel therapeutic strategies in future AD treatment, this review introduces the recent AD treatment technologies from three aspects, including nanoparticle (NP) based drug therapy, biological therapy and physical therapy. The nanoparticle-mediated therapeutic approaches at the nanomaterial-neural interface and biological system are described in detail, and in particular the magneto-regulated strategies by magnetic field actuating magnetic nanoparticles are highlighted. Promising application of magneto-mechanical force regulated strategy in future AD treatment is also addressed, which offer possibilities for the remote manipulation in a precise manner. In the future, it may be possible for physicians to realize a remote, precise and effective therapy for AD using magneto-mechanical force regulated technology based on the combination of magnetic nanoparticles and an external magnetic field.
    MeSH term(s) Humans ; Aged ; Alzheimer Disease/drug therapy ; Alzheimer Disease/diagnosis ; Neurodegenerative Diseases
    Language English
    Publishing date 2023-10-11
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2702241-9
    ISSN 2050-7518 ; 2050-750X
    ISSN (online) 2050-7518
    ISSN 2050-750X
    DOI 10.1039/d3tb01629c
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Regional intensity of biological disasters in farmland: quantitative assessment and spatiotemporal analysis

    Shen, Yajing / Wang, Xiong / Song, Xiaoqing / Xu, Huixiao

    Environ Sci Pollut Res. 2022 Sept., v. 29, no. 44 p.67402-67417

    2022  

    Abstract: Biological disasters in farmland have become a serious threat to global sustainability. Quantitative studies on spatiotemporal change in regional intensity of biological disasters in farmland (RIBDF) are crucial for promoting sustainable intensification ... ...

    Abstract Biological disasters in farmland have become a serious threat to global sustainability. Quantitative studies on spatiotemporal change in regional intensity of biological disasters in farmland (RIBDF) are crucial for promoting sustainable intensification of farmland use and global food security. Many studies have revealed the impacts of natural environment on biological disasters in farmland. However, research on the impacts of farmers’ activities on biological disasters remains very limited from the perspective of induced substitution in agricultural production. Based on the principle of induced substitution in agricultural production, a theoretical framework for the impacts of farmland use intensity (FUI), the occurrence intensity of biological disasters (OIBD), the natural loss intensity resulting from biological disasters (NLIBD), and the actual loss intensity controlled by human activities (ALIBD) on change in RIBDF was presented, and we therefore established an assessment model integrating these four key indices in this study. Taking Guangdong Province in China as the study area, this study analyzed the spatiotemporal changes in RIBDF from 1996 to 2017 and found that RIBDF increased overall with three change stages of slow growth, rapid growth, and decline at the provincial and regional levels. Moreover, the gravity center of RIBDF appeared to shift towards the coastal region in southwestern Guangdong at a speed of 18.20 km per year. The results reveal that the spatiotemporal change in RIBDF is determined by the key influencing factors including the substitution of chemical fertilizers for farmland and crop substitution. These findings suggest that it is necessary to expand the scale of farmland management and to encourage farmers to implement diversified cropping as well as chemical fertilizers reduction. The foremost contribution of this study is its exploration of an understanding of the linkage between farmland use activities characterized as induced substitution in agricultural production and biological disasters. Moreover, policy implications for sustainable intensification of farmland use were discussed based on these findings.
    Keywords agricultural land ; coasts ; food security ; gravity ; humans ; issues and policy ; models ; China
    Language English
    Dates of publication 2022-09
    Size p. 67402-67417.
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-022-20497-3
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  4. Article: Natural gum-based electronic ink with water-proofing self-healing and easy-cleaning properties for directly on-skin electronics

    Huang, Han / Feng, Yu / Yang, Xiong / Shen, Yajing

    Biosensors & bioelectronics. 2022 Oct. 15, v. 214

    2022  

    Abstract: On-skin electronic systems, which can facilitate noninvasive continuous acquisition of low-artifact physiological signals, are a promising technique for future wearable devices in healthcare. Inspired by the nature of Arabic gum (AG), we developed a ... ...

    Abstract On-skin electronic systems, which can facilitate noninvasive continuous acquisition of low-artifact physiological signals, are a promising technique for future wearable devices in healthcare. Inspired by the nature of Arabic gum (AG), we developed a costless, easy-to-prepare, easy-to-use, and environment-friendly electronic ink (E-ink) that can be used to construct multiform on-skin electronic systems through simple painting or stamping. In addition to its competitive electrical properties, the E-ink has the following advantages: waterproof (0.5 m/s water flushing for 10 s), self-healing (1.5 mm wide wound), and easy-cleaning (can be easily removed using cotton ball with 5% surfactant), making it environmentally tolerant and highly reliable for practical use. We demonstrated that our E-ink can act as electric wires for epidermal circuits, sensors to handle a variety of physiological data measurements. This research provides an effective strategy for direct integration of electronics and skin, which can accelerate the realization of the next generation of imperceptible, scalable, cost-effective and customized wearable devices.
    Keywords biosensors ; cost effectiveness ; cotton ; electronics ; gum arabic ; health services ; surfactants
    Language English
    Dates of publication 2022-1015
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 1011023-9
    ISSN 1873-4235 ; 0956-5663
    ISSN (online) 1873-4235
    ISSN 0956-5663
    DOI 10.1016/j.bios.2022.114547
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  5. Article ; Online: Photocatalytic C-N cross-coupling mediated by heterogeneous nickel-coordinated carbon nitride.

    Zhu, Qi / Zhao, En / Shen, Yajing / Chen, Zupeng / Fang, Weiwei

    Organic & biomolecular chemistry

    2023  Volume 21, Issue 20, Page(s) 4276–4281

    Abstract: An easy to prepare nickel-coordinated mesoporous graphitic carbon nitride (Ni-mpg-CN) was introduced as a heterogeneous photocatalyst, which efficiently accelerated the photocatalytic C-N cross-coupling of (hetero)aryl bromides and aliphatic amines, ... ...

    Abstract An easy to prepare nickel-coordinated mesoporous graphitic carbon nitride (Ni-mpg-CN) was introduced as a heterogeneous photocatalyst, which efficiently accelerated the photocatalytic C-N cross-coupling of (hetero)aryl bromides and aliphatic amines, delivering the desired monoaminated products in good yields. In addition, the concise synthesis of the pharmaceutical tetracaine was accomplished in the final stage, further highlighting the practical applicability.
    Language English
    Publishing date 2023-05-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d3ob00388d
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: A deep learning-based prediction model of college students' psychological problem categories for post-epidemic era-Taking college students in Jiangsu Province, China as an example.

    Liu, Yongheng / Shen, Yajing / Cai, Zhiyong

    Frontiers in psychology

    2022  Volume 13, Page(s) 975493

    Abstract: For a long time, it takes a lot of time and energy for psychological workers to classify the psychological problems of college students. In order to quickly and efficiently understand the common psychological problems of college students in the region ... ...

    Abstract For a long time, it takes a lot of time and energy for psychological workers to classify the psychological problems of college students. In order to quickly and efficiently understand the common psychological problems of college students in the region for real-time analysis in the post-epidemic era, 2,000 college students' psychological problems were selected as research data in the community question section of the "Su Xin" application, a psychological self-help and mutual aid platform for college students in Jiangsu Province. First, word segmentation, removal of stop words, establishment of word vectors, etc. were used for the preprocessing of research data. Secondly, it was divided into 9 common psychological problems by LDA clustering analysis, which also combined with previous researches. Thirdly, the text information was processed into word vectors and transferred to the Attention-Based Bidirectional Long Short-Term Memory Networks (AB-LSTM). The experimental results showed that the proposed model has a higher test accuracy of 78% compared with other models.
    Language English
    Publishing date 2022-08-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.975493
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Regional intensity of biological disasters in farmland: quantitative assessment and spatiotemporal analysis.

    Shen, Yajing / Wang, Xiong / Song, Xiaoqing / Xu, Huixiao

    Environmental science and pollution research international

    2022  Volume 29, Issue 44, Page(s) 67402–67417

    Abstract: Biological disasters in farmland have become a serious threat to global sustainability. Quantitative studies on spatiotemporal change in regional intensity of biological disasters in farmland (RIBDF) are crucial for promoting sustainable intensification ... ...

    Abstract Biological disasters in farmland have become a serious threat to global sustainability. Quantitative studies on spatiotemporal change in regional intensity of biological disasters in farmland (RIBDF) are crucial for promoting sustainable intensification of farmland use and global food security. Many studies have revealed the impacts of natural environment on biological disasters in farmland. However, research on the impacts of farmers' activities on biological disasters remains very limited from the perspective of induced substitution in agricultural production. Based on the principle of induced substitution in agricultural production, a theoretical framework for the impacts of farmland use intensity (FUI), the occurrence intensity of biological disasters (OIBD), the natural loss intensity resulting from biological disasters (NLIBD), and the actual loss intensity controlled by human activities (ALIBD) on change in RIBDF was presented, and we therefore established an assessment model integrating these four key indices in this study. Taking Guangdong Province in China as the study area, this study analyzed the spatiotemporal changes in RIBDF from 1996 to 2017 and found that RIBDF increased overall with three change stages of slow growth, rapid growth, and decline at the provincial and regional levels. Moreover, the gravity center of RIBDF appeared to shift towards the coastal region in southwestern Guangdong at a speed of 18.20 km per year. The results reveal that the spatiotemporal change in RIBDF is determined by the key influencing factors including the substitution of chemical fertilizers for farmland and crop substitution. These findings suggest that it is necessary to expand the scale of farmland management and to encourage farmers to implement diversified cropping as well as chemical fertilizers reduction. The foremost contribution of this study is its exploration of an understanding of the linkage between farmland use activities characterized as induced substitution in agricultural production and biological disasters. Moreover, policy implications for sustainable intensification of farmland use were discussed based on these findings.
    MeSH term(s) Agriculture/methods ; Disasters ; Farms ; Fertilizers/analysis ; Humans ; Spatio-Temporal Analysis
    Chemical Substances Fertilizers
    Language English
    Publishing date 2022-05-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-022-20497-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Natural gum-based electronic ink with water-proofing self-healing and easy-cleaning properties for directly on-skin electronics.

    Huang, Han / Feng, Yu / Yang, Xiong / Shen, Yajing

    Biosensors & bioelectronics

    2022  Volume 214, Page(s) 114547

    Abstract: On-skin electronic systems, which can facilitate noninvasive continuous acquisition of low-artifact physiological signals, are a promising technique for future wearable devices in healthcare. Inspired by the nature of Arabic gum (AG), we developed a ... ...

    Abstract On-skin electronic systems, which can facilitate noninvasive continuous acquisition of low-artifact physiological signals, are a promising technique for future wearable devices in healthcare. Inspired by the nature of Arabic gum (AG), we developed a costless, easy-to-prepare, easy-to-use, and environment-friendly electronic ink (E-ink) that can be used to construct multiform on-skin electronic systems through simple painting or stamping. In addition to its competitive electrical properties, the E-ink has the following advantages: waterproof (0.5 m/s water flushing for 10 s), self-healing (1.5 mm wide wound), and easy-cleaning (can be easily removed using cotton ball with 5% surfactant), making it environmentally tolerant and highly reliable for practical use. We demonstrated that our E-ink can act as electric wires for epidermal circuits, sensors to handle a variety of physiological data measurements. This research provides an effective strategy for direct integration of electronics and skin, which can accelerate the realization of the next generation of imperceptible, scalable, cost-effective and customized wearable devices.
    MeSH term(s) Biosensing Techniques ; Electronics ; Ink ; Water ; Wearable Electronic Devices
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2022-07-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1011023-9
    ISSN 1873-4235 ; 0956-5663
    ISSN (online) 1873-4235
    ISSN 0956-5663
    DOI 10.1016/j.bios.2022.114547
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Photothermal-Driven Liquid Crystal Elastomers: Materials, Alignment and Applications.

    Zhang, Wei / Nan, Yifei / Wu, Zongxuan / Shen, Yajing / Luo, Dan

    Molecules (Basel, Switzerland)

    2022  Volume 27, Issue 14

    Abstract: Liquid crystal elastomers (LCEs) are programmable deformable materials that can respond to physical fields such as light, heat, and electricity. Photothermal-driven LCE has the advantages of accuracy and remote control and avoids the requirement of high ... ...

    Abstract Liquid crystal elastomers (LCEs) are programmable deformable materials that can respond to physical fields such as light, heat, and electricity. Photothermal-driven LCE has the advantages of accuracy and remote control and avoids the requirement of high photon energy for photochemistry. In this review, we discuss recent advances in photothermal LCE materials and investigate methods for mechanical alignment, external field alignment, and surface-induced alignment. Advances in the synthesis and orientation of LCEs have enabled liquid crystal elastomers to meet applications in optics, robotics, and more. The review concludes with a discussion of current challenges and research opportunities.
    MeSH term(s) Elastomers/chemistry ; Electricity ; Liquid Crystals/chemistry ; Optics and Photonics
    Chemical Substances Elastomers
    Language English
    Publishing date 2022-07-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27144330
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Milli-scale cellular robots that can reconfigure morphologies and behaviors simultaneously.

    Yang, Xiong / Tan, Rong / Lu, Haojian / Fukuda, Toshio / Shen, Yajing

    Nature communications

    2022  Volume 13, Issue 1, Page(s) 4156

    Abstract: Modular robot that can reconfigure architectures and functions has advantages in unpredicted environment and task. However, the construction of modular robot at small-scale remains a challenge since the lack of reliable docking and detaching strategies. ... ...

    Abstract Modular robot that can reconfigure architectures and functions has advantages in unpredicted environment and task. However, the construction of modular robot at small-scale remains a challenge since the lack of reliable docking and detaching strategies. Here we report the concept of milli-scale cellular robot (mCEBOT) achieved by the heterogeneous assembly of two types of units (short and long units). Under the magnetic field, the proposed mCEBOT units can not only selectively assemble (e.g., end-by-end and side-by-side) into diverse morphologies corresponding to the unstructured environments, but also configure multi-modes motion behaviors (e.g., slipping, rolling, walking and climbing) based on the on-site task requirements. We demonstrate its adaptive mobility from narrow space to high barrier to wetting surface, and its potential applications in hanging target taking and environment exploration. The concept of mCEBOT offers new opportunities for robot design, and will broaden the field of modular robot in both miniaturization and functionalization.
    MeSH term(s) Magnetic Fields ; Miniaturization ; Motion ; Robotics ; Walking
    Language English
    Publishing date 2022-07-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-022-31913-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top