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  1. AU="Shen Jianghua"
  2. AU="Storey J."
  3. AU="Ruby Espejo-Fonseca"
  4. AU="Gupta, Abha A"
  5. AU="Mei, Yingbing"
  6. AU="Han, Chenguang"
  7. AU="Ayoub, Isabelle"
  8. AU="Spencer, Sean P"
  9. AU="Papathemelis, Thomas"
  10. AU="Tzerefos, Christos"
  11. AU="Eefje Belt-van Zoen"
  12. AU="Rahmanian, Vahid"
  13. AU="Øyen, Martin Øhlund"
  14. AU="Xinyun Xuan"
  15. AU="Dana L. M. Campbell"
  16. AU="Mukta Roy"
  17. AU="Martha Funabashi"
  18. AU="Vasina, Svetlana"
  19. AU=Reber Stephan A.
  20. AU="Kenan Onel"
  21. AU="Lawrence, Marc R"
  22. AU="Zeiler, Frederick A"
  23. AU="de la Cueva, Pablo"
  24. AU="Fuh, Jerry Ying Hsi"
  25. AU="Park, Adrian J"
  26. AU="Joshi, K D"

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  1. Artikel ; Online: Potential approaches for intervening aging

    Shen Jianghua / Liu Guang-Hui / Song Moshi

    National Science Open, Vol

    2022  Band 1

    Schlagwörter Science ; Q ; Engineering (General). Civil engineering (General) ; TA1-2040
    Sprache Englisch
    Erscheinungsdatum 2022-08-01T00:00:00Z
    Verlag Science Press
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Risk factors for acute kidney injury after major abdominal surgery in the elderly aged 75 years and above.

    Shen, Jianghua / Chu, Yanqi / Wang, Chaodong / Yan, Suying

    BMC nephrology

    2022  Band 23, Heft 1, Seite(n) 224

    Abstract: Objectives: The study aimed to investigate the incidence and risk factors of acute kidney injury (AKI) in elderly patients (aged ≥ 75 years) undergoing major nonvascular abdominal surgery.: Methods: The study was a retrospective study that evaluated ... ...

    Abstract Objectives: The study aimed to investigate the incidence and risk factors of acute kidney injury (AKI) in elderly patients (aged ≥ 75 years) undergoing major nonvascular abdominal surgery.
    Methods: The study was a retrospective study that evaluated the incidence of AKI in patients within 48 h after major abdominal surgeries. Patients' preoperative characteristics and intraoperative management, including the use of nephrotoxic medications, were evaluated for associations with AKI using a logistic regression model.
    Results: A total of 573 patients were included in our analysis. A total of 33 patients (5.76%) developed AKI, and 30 (90.91%), 2 (6.06%) and 1 (3.03%) reached the AKI stages 1, 2 and 3, respectively. Older age (adjusted OR, aOR 1.112, 95% confidence interval, CI 1.020-1.212), serum albumin (aOR 0.900, 95% CI 0.829-0.977), baseline eGFR (aOR 3.401, 95% CI 1.479-7.820), the intraoperative occurrence of hypotension (aOR 3.509, 95% CI 1.553-7.929), and the use of hydroxyethyl starch in combination with nonsteroidal anti-inflammatory drugs (aOR 3.596, 95% CI 1.559-8.292) or furosemide (aOR 5.724, 95% CI 1.476-22.199) were independent risk factors for postoperative AKI.
    Conclusions: Several risk factors, including intraoperative combined administration of HES and furosemide, are independent factors for AKI during abdominal surgeries. Anesthesiologists and surgeons should take precautions in treating at-risk patients.
    Mesh-Begriff(e) Acute Kidney Injury/epidemiology ; Acute Kidney Injury/etiology ; Aged ; Furosemide ; Humans ; Hydroxyethyl Starch Derivatives/adverse effects ; Postoperative Complications/chemically induced ; Postoperative Complications/epidemiology ; Retrospective Studies ; Risk Factors
    Chemische Substanzen Hydroxyethyl Starch Derivatives ; Furosemide (7LXU5N7ZO5)
    Sprache Englisch
    Erscheinungsdatum 2022-06-23
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041348-8
    ISSN 1471-2369 ; 1471-2369
    ISSN (online) 1471-2369
    ISSN 1471-2369
    DOI 10.1186/s12882-022-02822-7
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Unraveling the dispersion mechanism of carbon nanotubes in aluminum powder particles during high energy ball milling by FIB-TEM study

    Cao, Lin / Zhen, Biao / Wan, Jie / Shen, Jianghua / Li, Shufeng / Liu, Shuiqing / Li, Jinshan

    Powder Technology. 2023, p.118339-

    2023  , Seite(n) 118339–

    Abstract: For the development of high-performance aluminum (Al) matrix composites reinforced with carbon nanotubes (CNTs), high energy ball milling (HEBM) is the most prevalent method to disperse CNTs in Al powder. However, the dispersion mechanism of CNTs in Al ... ...

    Abstract For the development of high-performance aluminum (Al) matrix composites reinforced with carbon nanotubes (CNTs), high energy ball milling (HEBM) is the most prevalent method to disperse CNTs in Al powder. However, the dispersion mechanism of CNTs in Al powder is still unclear, mainly because it is difficult to characterize CNTs when they are buried inside Al powder particles. Herein, focused-ion-beam-assisted transmission electron microscopy observation of CNTs in Al powder via HEBM with various milling times was conducted. Results showed that with increasing HEBM time, CNTs clusters were firstly broken up to be dispersed shorter-lengthed CNTs on the surface of Al flakes with gradually reduced thickness. Afterward, cold-welding of Al flakes was the predominant phenomenon, which resulted in re-spheroidization of Al powders and homogeneously dispersed CNTs. This study may provide guidance for controlling and optimizing the HEBM process to disperse CNTs in Al matrix towards the development of high-performance CNTs/Al composites.
    Schlagwörter aluminum ; carbon nanotubes ; energy ; transmission electron microscopy ; Aluminum matrix composites (AMCs) ; Carbon nanotubes (CNTs) ; High energy ball milling (HEBM) ; Cold welding process ; Dispersion mechanism
    Sprache Englisch
    Erscheinungsort Elsevier B.V.
    Dokumenttyp Artikel ; Online
    Anmerkung Pre-press version
    ISSN 0032-5910
    DOI 10.1016/j.powtec.2023.118339
    Datenquelle NAL Katalog (AGRICOLA)

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  4. Dissertation / Habilitation ; Online: Mechanical behavior and deformation mechanism in light metals at different strain rates

    Shen, Jianghua

    2015  

    Abstract: Developing light metals that have desirable mechanical properties is always the object of the endeavor of materials scientists. Magnesium (Mg), one of the lightest metals, had been used widely in military and other applications. Yet, its relatively poor ... ...

    Abstract Developing light metals that have desirable mechanical properties is always the object of the endeavor of materials scientists. Magnesium (Mg), one of the lightest metals, had been used widely in military and other applications. Yet, its relatively poor formability, as well as its relatively low absolute strength, in comparison with other metals such as aluminum and steels, caused the use of Mg to be discontinued after World War II. Owing to the subsequent energy crisis of the seventies, recently, interest in Mg development has been rekindled in the materials community. The main focus of research has been quite straight-forward: increasing the strength and formability such that Mg and its alloys may replace aluminum alloys and steels to become yet another choice for structural materials. This dissertation work is mainly focused on fundamental issues related to Mg and its alloys. More specifically, it investigates the mechanical behavior of different Mg-based materials and the corresponding underlying deformation mechanisms. In this context, we examine the factors that affect the microstructure and mechanical properties of pure Mg, binary Mg-alloy (with addition of yttrium), more complex Mg-based alloys with and without the addition of lanthanum, and finally Mg-based metal matrix composites (MMCs) reinforced with ex-situ ceramic particles. More specifically, the effects of the following factors on the mechanical properties of Mg-based materials will be investigated: addition of rare earths (yttrium and lanthanum), in-situ/ex-situ formed particles, particle size or volume fraction and materials processing, effect of thermal-mechanical treatment (severe plastic deformation and warm extrusion), and so on and so forth. A few interesting results have been found from this dissertation work: (i) although rare earths may improve the room temperature ductility of well-annealed Mg, the addition of yttrium results in ultrafine and un-recrystallized grains in the Mg-Y alloy subjected to equal channel angular pressing (ECAP); (ii) the reverse volume fraction effect arises as the volume fraction of nano-sized ex-situ formed reinforcements is beyond 10%; (iii) nano-particles are more effective in strengthening Mg than micro-particles when the volume fraction is below 10%; (iv) complete dynamic recovery and/or recrystallization is required to accomplish the moderate ductility in Mg, together with a strong matrix-particle bonding if it is a Mg-based composite; and (v) localized shear failure is observed in all Mg samples, recrystallized completely, which is attributed to the reduced strain hardening rate as a result of the exhaustion of twinning and/or dislocation multiplication.
    Schlagwörter Mechanics|Mechanical engineering|Materials science
    Thema/Rubrik (Code) 669
    Sprache ENG
    Erscheinungsdatum 2015-01-01 00:00:01.0
    Verlag The University of North Carolina at Charlotte
    Erscheinungsland us
    Dokumenttyp Dissertation / Habilitation ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: Enhanced adiabatic shear band susceptibility in Ti composites reinforced with quasi-continuous network of graphene nanosheets

    Shi, Wendi / Yan, Qi / Shen, Jianghua / Zhen, Biao / Li, Yulong

    Composites Part A. 2022 Sept., v. 160 p.107055-

    2022  

    Abstract: Graphene nanosheets (GNSs) can remarkably advance the mechanical properties of titanium metal matrix composites (TiMCs) by forming a quasi-continuous network architecture. However, the failure mechanism of the network architecture, especially under ... ...

    Abstract Graphene nanosheets (GNSs) can remarkably advance the mechanical properties of titanium metal matrix composites (TiMCs) by forming a quasi-continuous network architecture. However, the failure mechanism of the network architecture, especially under impact loading, has never been truly understood. In this work, a Ti–6Al–4V based composite reinforced with GNSs was adopted to study the failure behavior of the quasi-continuous network architecture of GNSs under impact loading, as well as its influence on macroscopic behavior of TiMCs. Experimental results revealed that, the quasi-continuous networked TiMCs exhibited a propensity of failure by adiabatic shearing, where the shear band seemed to propagate (and probably also initiate) along the network architecture. Microstructural observation suggested that, instead of grain size or texture, the enhanced ASB susceptibility of the composite is attributed to the high defect density induced by networked reinforcement. Then, a comprehensive discussion relates the enhanced ASB susceptibility quantitatively with adiabatic shear dissipation energy.
    Schlagwörter energy ; graphene ; nanosheets ; texture ; titanium ; Graphite ; Mechanical properties ; Microstructural analysis ; Impact behavior ; Shear bands
    Sprache Englisch
    Erscheinungsverlauf 2022-09
    Erscheinungsort Elsevier Ltd
    Dokumenttyp Artikel ; Online
    ZDB-ID 2012223-8
    ISSN 1359-835X
    ISSN 1359-835X
    DOI 10.1016/j.compositesa.2022.107055
    Datenquelle NAL Katalog (AGRICOLA)

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  6. Artikel ; Online: Hyperbranched polymer functionalized flexible perovskite solar cells with mechanical robustness and reduced lead leakage.

    Li, Zhihao / Jia, Chunmei / Wan, Zhi / Xue, Jiayi / Cao, Junchao / Zhang, Meng / Li, Can / Shen, Jianghua / Zhang, Chao / Li, Zhen

    Nature communications

    2023  Band 14, Heft 1, Seite(n) 6451

    Abstract: Perovskite solar cells (PSCs) are multilayer structures. The interface between electron transport layer and perovskite is the mechanical weakest point in flexible PSCs due to its low fracture energy. Herein, we develop a highly adhesive polyamide-amine- ... ...

    Abstract Perovskite solar cells (PSCs) are multilayer structures. The interface between electron transport layer and perovskite is the mechanical weakest point in flexible PSCs due to its low fracture energy. Herein, we develop a highly adhesive polyamide-amine-based hyperbranched polymers to reinforce the interface. The interface fracture energy is improved from 1.08 to 2.13 J·m
    Sprache Englisch
    Erscheinungsdatum 2023-10-13
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-41931-1
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Fabrication of a micro/nanocomposite structure on the surface of high oxygen concentration titanium to promote bone formation.

    Luo, Huiwen / Diao, Xiaoou / Qian, Fei / Shi, Wendi / Li, Kai / Liu, Huan / Wu, Yulu / Shen, Jianghua / Xin, Haitao

    Biomaterials advances

    2023  Band 154, Seite(n) 213631

    Abstract: This study investigated the properties of the micro/nano composite structure on the surface of high oxygen concentration titanium (HOC-Ti) after anodic oxidation modification (HOC-NT) and evaluated its biocompatibility as a dental implant material in ... ...

    Abstract This study investigated the properties of the micro/nano composite structure on the surface of high oxygen concentration titanium (HOC-Ti) after anodic oxidation modification (HOC-NT) and evaluated its biocompatibility as a dental implant material in vitro and in vivo. HOC-Ti was produced by titanium powders and rutile powders using the powder metallurgy method. Its surface was modified by anodic oxidation. After detecting the electrochemical characteristics, the surface properties of HOC-NT were investigated. MC3T3 and MLO-Y4 cells were employed to evaluate the biocompatibility of HOC-NT and cocultured to study the effects of the changes in osteocytes induced by HOC-NT on osteoblasts. While, its possible mechanism was investigated. In addition, osseointegration around the HOC-NT implant was investigated through in vivo experiments. The results showed that a unique micronano composite structure on the HOC-Ti surface with excellent hydrophilicity and suitable surface roughness was created after anodic oxidation promoted by its electrochemical characteristics. The YAP protein may play an important role in regulating bone remodeling by β-catenin and Rankl/OPG Signaling Pathways. An in vivo study also revealed an accelerated formation rate of new bone and more stable osseointegration around the HOC-NT implant. In view of all experimental results, it could be concluded that the unique morphology of HOC-NT has enhanced physicochemical and biological properties. The promotion of bone formation around implants indicated the feasibility of HOC-NT for applications in oral implants.
    Mesh-Begriff(e) Osteogenesis ; Titanium/pharmacology ; Osseointegration/physiology ; Nanocomposites ; Oxygen/pharmacology
    Chemische Substanzen Titanium (D1JT611TNE) ; Oxygen (S88TT14065)
    Sprache Englisch
    Erscheinungsdatum 2023-09-21
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ISSN 2772-9508
    ISSN (online) 2772-9508
    DOI 10.1016/j.bioadv.2023.213631
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Simultaneously improving mechanical, thermal, and anti-wear properties of Ti alloys using 3D-networked graphene as reinforcement

    Yan, Qi / Zhen, Biao / Ye, Wenting / Zhang, Tao / Wan, Jie / Zhou, Qing / Shen, Jianghua / Li, Jinshan / Huang Lü, Wenfeng / Wang, Hao

    Carbon. 2023 Sept., v. 213 p.118152-

    2023  

    Abstract: The simultaneous improvement of mechanical and functional properties of Ti alloys is of considerable significance for their diverse applications and service life. Incorporating graphene with Ti is hoping to realize that, however, it is challenging to ... ...

    Abstract The simultaneous improvement of mechanical and functional properties of Ti alloys is of considerable significance for their diverse applications and service life. Incorporating graphene with Ti is hoping to realize that, however, it is challenging to achieve the improvement because of the poor chemical stability of carbon/Ti systems. This challenge becomes particularly significant when using high carbon-content reinforcements, as the reinforcement agglomeration is considered to adversely affect composite performances. In this work, an efficient powder metallurgy method was developed to fabricate titanium matrix composites reinforced by a high content of graphene nanosheets (GNSs). Quasi-continuous GNSs were arranged in a 3D network and were surrounded by in-situ TiC. The results revealed that the load-transfer and solid-solution strengthening factors contributed to the high mechanical strength of the composites. Moreover, the GNS networks conduced to the improvement of thermal conduction, reduced the total weight, and enhanced the anti-wear performance of the composites via self-lubrication. Furthermore, the proposed approach can be applied to other carbon/metal composites for achieving significant improvements in their performance.
    Schlagwörter durability ; graphene ; heat transfer ; metallurgy ; nanosheets ; strength (mechanics) ; titanium ; Titanium matrix composites ; Strength ; Thermal conductivity ; Anti-wear
    Sprache Englisch
    Erscheinungsverlauf 2023-09
    Umfang p. 118152
    Erscheinungsort Elsevier Ltd
    Dokumenttyp Artikel ; Online
    Anmerkung Pre-press version
    ISSN 0008-6223
    DOI 10.1016/j.carbon.2023.118152
    Datenquelle NAL Katalog (AGRICOLA)

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  9. Artikel ; Online: Dynamic self-strengthening of a bio-nanostructured armor - conch shell.

    Li, Haoze / Shen, Jianghua / Wei, Qiuming / Li, Xiaodong

    Materials science & engineering. C, Materials for biological applications

    2019  Band 103, Seite(n) 109820

    Abstract: Bio-nanowire structured armors - conch shells, which are often collected as art pieces, possess a special function - an unusual resilience against high speed predatory attacks. Under high-strain-rate compression (strain rate ~ ... ...

    Abstract Bio-nanowire structured armors - conch shells, which are often collected as art pieces, possess a special function - an unusual resilience against high speed predatory attacks. Under high-strain-rate compression (strain rate ~10
    Mesh-Begriff(e) Animal Shells/chemistry ; Animal Shells/ultrastructure ; Animals ; Biomechanical Phenomena ; Microscopy, Electron, Scanning ; Microscopy, Electron, Transmission ; Nanostructures/ultrastructure ; Snails/anatomy & histology
    Sprache Englisch
    Erscheinungsdatum 2019-06-01
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2012160-X
    ISSN 1873-0191 ; 0928-4931
    ISSN (online) 1873-0191
    ISSN 0928-4931
    DOI 10.1016/j.msec.2019.109820
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Association of preoperative medication with postoperative length of stay in elderly patients undergoing hip fracture surgery.

    Shen, Jianghua / Yu, Yahui / Wang, Chaodong / Chu, Yanqi / Yan, Suying

    Aging clinical and experimental research

    2020  Band 33, Heft 3, Seite(n) 641–649

    Abstract: Background: For elderly patients who are about to undergo surgery, research on the effects of preoperative medication on postoperative outcomes is rare, especially preoperative discontinuation-requiring medication (PDRM) which needed to be discontinued ... ...

    Abstract Background: For elderly patients who are about to undergo surgery, research on the effects of preoperative medication on postoperative outcomes is rare, especially preoperative discontinuation-requiring medication (PDRM) which needed to be discontinued because of its increased risk of postoperative complications.
    Aim: To investigate whether preoperative medication (PDRM and polypharmacy) is associated with postoperative length of hospital stay (LOS) in elderly patients undergoing hip fracture surgery.
    Methods: Patients aged ≥ 65 who were scheduled for hip (limited to femoral tuberosity) fracture surgery were included. Baseline characteristics, preoperative medication and postoperative LOS were collected from the electronic medical record. The primary outcome was postoperative LOS.
    Results: A total of 369 hip fracture patients were included. There were 188 and 122 patients exposed to PDRM and polypharmacy, respectively. Multivariate analysis models were constructed using significant factors for prolonged postoperative hospital stay from univariate analysis: Model I (body mass index (BMI), Charlson comorbidity index (CCI) ≥ 7, creatinine clearance rate (Ccr) < 60 and PDRM) and Model II (BMI, Ccr ≥ 7, Ccr < 60 and polypharmacy). CCI was the most significant factor. Its adjusted odds ratio was as large as 2.7 and attributable risk was 63%. In preoperative medication use, both polypharmacy and PDRM showed significant association with postoperative LOS.
    Conclusion: The present study supported the impact of PDRM on postoperative LOS in geriatric hip fracture patients. The results added a further aspect to preoperative medication optimization in elderly patients undergoing hip fracture surgery.
    Mesh-Begriff(e) Aged ; Hip Fractures/surgery ; Humans ; Length of Stay ; Odds Ratio ; Postoperative Complications/epidemiology ; Retrospective Studies ; Risk Factors
    Sprache Englisch
    Erscheinungsdatum 2020-05-21
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2104785-6
    ISSN 1720-8319 ; 1594-0667
    ISSN (online) 1720-8319
    ISSN 1594-0667
    DOI 10.1007/s40520-020-01567-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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