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  1. AU="Shengli, Chen"
  2. AU="Valdés-Hernández, Jesús"
  3. AU="Wong, Wei Yin"
  4. AU="Konstantinos Koutroumpas"
  5. AU="Kumar Thulasi"
  6. AU="Elbe, Peter"
  7. AU=Ryffel Gerhart U
  8. AU="López Panadés, Maria"
  9. AU="Tormo, Hélène"
  10. AU="Gardham, Alice"
  11. AU="Chisa Inoue"
  12. AU=Savcenko Michal AU=Savcenko Michal
  13. AU=Dinda Biswanath AU=Dinda Biswanath
  14. AU="Heikinheimo Annamari"
  15. AU="Currie, Geoffrey"
  16. AU="Konno, Adriana Y C"
  17. AU="Nashmi, Raad"
  18. AU="Doligkeit, Daniel"
  19. AU="Caparello, Basilio"
  20. AU="Fricke, T T"
  21. AU="Mummery, C J"
  22. AU="Krantz, Emily"
  23. AU="Bedoya-Arias, Juan E"
  24. AU="Zhou, Heyang"
  25. AU=Latson Larry A
  26. AU=Alhuzimi Eman
  27. AU="Wuerzberger-Davis, Shelly M"
  28. AU="Clippinger, Amy J"
  29. AU="M. S. Islam"
  30. AU="Borrego-Jiménez, Jaime"
  31. AU="Kaoru Dohi"
  32. AU="Tornai, Gábor J"
  33. AU="D'Avella, Christopher"
  34. AU="Lim, Boon L."
  35. AU="Heselden, Marie"
  36. AU=Dias?Polak David
  37. AU="Shahid Umar"
  38. AU="Abu-Shmais, Alexandria A"
  39. AU="Takenaka, Haruka"
  40. AU="Bramley, Andrea"
  41. AU="Sang Hong Lee"

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  1. Artikel ; Online: Digital Transformation and Enterprise Resilience

    Dong Wang / Shengli Chen

    Sustainability, Vol 14, Iss 14218, p

    Evidence from China

    2022  Band 14218

    Abstract: Digital transformation has become a key strategy for enterprises to enhance resilience in effectively responding to external shocks and achieving sustainable development in the context of the global spread of the epidemic and the increase of ... ...

    Abstract Digital transformation has become a key strategy for enterprises to enhance resilience in effectively responding to external shocks and achieving sustainable development in the context of the global spread of the epidemic and the increase of uncertainties in external environments. In this paper, the impact and mechanism of digital transformation on corporate resilience are examined based on data of listed Chinese companies from 2007 to 2020. Our research results reveal that digital transformation can significantly enhance corporate resilience. This conclusion remains unchanged after controlling for endogeneity issues and performing various robustness analyses. Digital transformation has heterogeneous effects in the dimensions of corporate property rights, industries, and regions, with state-owned enterprises, manufacturing, and eastern enterprises benefiting more. Digital transformation primarily reinforces corporate resilience through mechanisms that improve human capital, strengthen innovation capabilities, ease financing constraints, and enhance internal control. Therefore, the government must guide macro policies, pay attention to the leading role of state-owned enterprises, and narrow the regional digital divide to better enact digital transformation and promote corporate resilience. Simultaneously, in the process of digital transformation, enterprises should combine the characteristics and development stages of their industry by exploring the development requirements and strategically implementing them in stages in a targeted manner. The findings of this paper provide new empirical evidence for the economic impact of enterprise digital transformation, as well as useful inspiration for enhancing enterprise resilience and promoting high-quality development.
    Schlagwörter digital transformation ; enterprise resilience ; digital economy ; digital technology ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Thema/Rubrik (Code) 650
    Sprache Englisch
    Erscheinungsdatum 2022-10-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Fabrication of Soft-Oxometalates {Mo132} Clusters With Novel Azobenzene Surfactants

    Zhe Wang / Xuefeng Li / Shengli Chen / Jinfeng Dong

    Frontiers in Chemistry, Vol

    Size Control by Micelles and Light

    2021  Band 9

    Abstract: Soft-oxometalates (SOMs) are colloid suspensions of superstructured assemblies of polyoxometalates (POMs) and are found to be very effective photo-catalysts in a number of chemical reactions. The stabilization of SOMs generally requires legends or ... ...

    Abstract Soft-oxometalates (SOMs) are colloid suspensions of superstructured assemblies of polyoxometalates (POMs) and are found to be very effective photo-catalysts in a number of chemical reactions. The stabilization of SOMs generally requires legends or stabilizers, e.g., polymers and surfactants. In this paper, a light responsive azobenzene surfactant, C10AZOC2N3, was developed and used to stable {Mo132} SOMs. Various techniques such as Dynamic light scattering, TEM, UV-Vis spectra and cyclic voltammetry were employed to characterize the experimental results. The outstanding structure-directing effect of surfactant self-assembly micelles in solution on inorganic counter-anions was demonstrated. Different amount of cyclohexane was solubilized into C10AZOC2N3 micelles to successfully control the size of {Mo132} SOMs cluster. Furthermore, the clusters exposed to UV light for a certain time can be served as a second trigger to control the size of SOMs due to the trans-cis conformation transition of surfactant molecules. The redox potentials of C10AZOC2N3-{Mo132} SOMs were investigated as the cluster size varied. Interestingly, the redox potential of {Mo132} was not affected by the cluster size, indicating that the presence of surfactant did not change the main function of {Mo132} as an electrochemical catalyst, but merely assisted in the size control of SOM aggregation.
    Schlagwörter soft-oxometalates ; azobenzene surfactants ; solubilization ; light response ; redox potential ; Chemistry ; QD1-999
    Thema/Rubrik (Code) 540
    Sprache Englisch
    Erscheinungsdatum 2021-02-01T00:00:00Z
    Verlag Frontiers Media S.A.
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Simulation Analysis of the Dispersion of Typical Marine Pollutants by Fusion of Multiple Processes

    Xueqing Guo / Yi Liu / Jian-Min Zhang / Shengli Chen / Sunwei Li / Zhen-Zhong Hu

    Sustainability, Vol 15, Iss 10547, p

    2023  Band 10547

    Abstract: The rapid development of coastal economies has aggravated the problem of pollution in the coastal water bodies of various countries. Numerous incidents of massive-scale marine life deaths have been reported because of the excessive discharge of ... ...

    Abstract The rapid development of coastal economies has aggravated the problem of pollution in the coastal water bodies of various countries. Numerous incidents of massive-scale marine life deaths have been reported because of the excessive discharge of industrial and agricultural wastewater. To investigate the diffusion of typical pollutants after discharge, in this study, a multi-process fusion simulation analysis model of pollutants under the action of ocean currents was established based on the concentration analysis method. Furthermore, key technologies involved, such as the parameter value, data selection, and visualization, were investigated. The iterative analysis and programming realization of three independent sub-processes, such as pollutant diffusion and transport, and the drift path and concentration distribution of pollutants after their discharge into the sea, were visualized. The case study revealed that the increase in the concentration of pollutants in the ocean was affected by the diffusion sub-process, and the transport sub-process plays a critical role in the long-distance transport of pollutants. The proposed method can provide technical support for marine environmental risk assessment and dynamic tracking of marine pollutants.
    Schlagwörter typical pollutants ; concentration analysis ; multi-process ; numerical simulation ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Thema/Rubrik (Code) 333
    Sprache Englisch
    Erscheinungsdatum 2023-07-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Multiphase and multiparameter MRI-based radiomics for prediction of tumor response to neoadjuvant therapy in locally advanced rectal cancer

    Hongyan Huang / Lujun Han / Jianbo Guo / Yanyu Zhang / Shiwei Lin / Shengli Chen / Xiaoshan Lin / Caixue Cheng / Zheng Guo / Yingwei Qiu

    Radiation Oncology, Vol 18, Iss 1, Pp 1-

    2023  Band 11

    Abstract: Abstract Background To develop and validate radiomics models for prediction of tumor response to neoadjuvant therapy (NAT) in patients with locally advanced rectal cancer (LARC) using both pre-NAT and post-NAT multiparameter magnetic resonance imaging ( ... ...

    Abstract Abstract Background To develop and validate radiomics models for prediction of tumor response to neoadjuvant therapy (NAT) in patients with locally advanced rectal cancer (LARC) using both pre-NAT and post-NAT multiparameter magnetic resonance imaging (mpMRI). Methods In this multicenter study, a total of 563 patients were included from two independent centers. 453 patients from center 1 were split into training and testing cohorts, the remaining 110 from center 2 served as an external validation cohort. Pre-NAT and post-NAT mpMRI was collected for feature extraction. The radiomics models were constructed using machine learning from a training cohort. The accuracy of the models was verified in a testing cohort and an independent external validation cohort. Model performance was evaluated using area under the curve (AUC), sensitivity, specificity, positive predictive value, and negative predictive value. Results The model constructed with pre-NAT mpMRI had favorable accuracy for prediction of non-response to NAT in the training cohort (AUC = 0.84), testing cohort (AUC = 0.81), and external validation cohort (AUC = 0.79). The model constructed with both pre-NAT and post-NAT mpMRI had powerful diagnostic value for pathologic complete response in the training cohort (AUC = 0.86), testing cohort (AUC = 0.87), and external validation cohort (AUC = 0.87). Conclusions Models constructed with multiphase and multiparameter MRI were able to predict tumor response to NAT with high accuracy and robustness, which may assist in individualized management of LARC.
    Schlagwörter Locally advanced rectal cancer ; Neoadjuvant therapy ; Tumor response ; MRI ; Radiomics ; Medical physics. Medical radiology. Nuclear medicine ; R895-920 ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2023-10-01T00:00:00Z
    Verlag BMC
    Dokumenttyp Artikel ; Online
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  5. Artikel ; Online: Revealing the role of double-layer microenvironments in pH-dependent oxygen reduction activity over metal-nitrogen-carbon catalysts

    Peng Li / Yuzhou Jiao / Yaner Ruan / Houguo Fei / Yana Men / Cunlan Guo / Yuen Wu / Shengli Chen

    Nature Communications, Vol 14, Iss 1, Pp 1-

    2023  Band 12

    Abstract: Abstract A standing puzzle in electrochemistry is that why the metal-nitrogen-carbon catalysts generally exhibit dramatic activity drop for oxygen reduction when traversing from alkaline to acid. Here, taking FeCo-N6-C double-atom catalyst as a model ... ...

    Abstract Abstract A standing puzzle in electrochemistry is that why the metal-nitrogen-carbon catalysts generally exhibit dramatic activity drop for oxygen reduction when traversing from alkaline to acid. Here, taking FeCo-N6-C double-atom catalyst as a model system and combining the ab initio molecular dynamics simulation and in situ surface-enhanced infrared absorption spectroscopy, we show that it is the significantly distinct interfacial double-layer structures, rather than the energetics of multiple reaction steps, that cause the pH-dependent oxygen reduction activity on metal-nitrogen-carbon catalysts. Specifically, the greatly disparate charge densities on electrode surfaces render different orientations of interfacial water under alkaline and acid oxygen reduction conditions, thereby affecting the formation of hydrogen bonds between the surface oxygenated intermediates and the interfacial water molecules, eventually controlling the kinetics of the proton-coupled electron transfer steps. The present findings may open new and feasible avenues for the design of advanced metal-nitrogen-carbon catalysts for proton exchange membrane fuel cells.
    Schlagwörter Science ; Q
    Thema/Rubrik (Code) 541
    Sprache Englisch
    Erscheinungsdatum 2023-10-01T00:00:00Z
    Verlag Nature Portfolio
    Dokumenttyp Artikel ; Online
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  6. Artikel: Interplay between Covalent and Noncovalent Interactions in Electrocatalysis

    Huang, Jun / Shengli Chen

    Journal of physical chemistry. 2018 Oct. 22, v. 122, no. 47

    2018  

    Abstract: Electrocatalysis has been advanced to a point that understanding how noncovalent interactions interplay with covalent interactions becomes essential to precision design of efficient electrocatalysts. However, a conceptual framework for facilitating such ... ...

    Abstract Electrocatalysis has been advanced to a point that understanding how noncovalent interactions interplay with covalent interactions becomes essential to precision design of efficient electrocatalysts. However, a conceptual framework for facilitating such understandings is yet missing; existing theories of electrocatalysis usually neglect noncovalent interactions. To fill in this gap, this study presents a refined theory of electrocatalysis by adding a noncovalent term that is self-consistently derived from a mean-field electrical double-layer (EDL) model into the model Hamiltonian, in addition to the electronic interaction term described by the Anderson–Newns model and the solvent term inspired by the Marcus theory. Applying the Green function technique allows us to portray the potential energy surface, to pinpoint multiple states along the reaction pathway and further to determine the reaction free energy and activation energies. Multifaceted interplay between covalent and noncovalent interactions is revealed. On the one hand, chemisorption-induced surface dipoles modify the work function and electrostatic properties of the metal, leading to nonmonotonicity in the surface charging relation and then the activation energy profile. As an immediate consequence, the sum of anodic and cathodic transfer coefficient is less than unity and the cathodic transfer coefficient can even be negative. On the other hand, EDL effects modulate covalent interactions, in return, via dictating the electrochemical potential of ions. The theory brings forth a new adsorption isotherm, which provides fundamental insights into the perplexing strong indirect adsorbate–adsorbate interactions, and furnishes a theoretical approach to analyze the electrosorption valency as well.
    Schlagwörter activation energy ; chemical bonding ; electrochemistry ; Gibbs free energy ; ions ; models ; potential energy ; solvents ; sorption isotherms
    Sprache Englisch
    Erscheinungsverlauf 2018-1022
    Umfang p. 26910-26921.
    Erscheinungsort American Chemical Society
    Dokumenttyp Artikel
    ISSN 1932-7455
    DOI 10.1021/acs.jpcc.8b07534
    Datenquelle NAL Katalog (AGRICOLA)

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  7. Artikel ; Online: Immune Evasion of Mycoplasma bovis

    Hussam Askar / Shengli Chen / Huafang Hao / Xinmin Yan / Lina Ma / Yongsheng Liu / Yuefeng Chu

    Pathogens, Vol 10, Iss 3, p

    2021  Band 297

    Abstract: Mycoplasma bovis (M. bovis) causes various chronic inflammatory diseases, including mastitis and bronchopneumonia, in dairy and feed cattle. It has been found to suppress the host immune response during infection, leading to the development of chronic ... ...

    Abstract Mycoplasma bovis (M. bovis) causes various chronic inflammatory diseases, including mastitis and bronchopneumonia, in dairy and feed cattle. It has been found to suppress the host immune response during infection, leading to the development of chronic conditions. Both in vitro and in vivo studies have confirmed that M. bovis can induce proinflammatory cytokines and chemokines in the host. This consists of an inflammatory response in the host that causes pathological immune damage, which is essential for the pathogenic mechanism of M. bovis . Additionally, M. bovis can escape host immune system elimination and, thus, cause chronic infection. This is accomplished by preventing phagocytosis and inhibiting key responses, including the neutrophil respiratory burst and the development of nitric oxide (NO) and inducible nitric oxide synthase (iNOS) that lead to the creation of an extracellular bactericidal network, in addition to inhibiting monocyte and alveolar macrophage apoptosis and inducing monocytes to produce anti-inflammatory factors, thus inducing the apoptosis of peripheral blood mononuclear cells (PBMCs), inhibiting their proliferative response and resulting in their invasion. Together, these conditions lead to long-term M. bovis infection. In terms of the pathogenic mechanism, M. bovis may invade specific T-cell subsets and induce host generation of exhausted T-cells, which helps it to escape immune clearance. Moreover, the M. bovis antigen exhibits high-frequency variation in size and expression period, which allows it to avoid activation of the host humoral immune response. This review includes some recent advances in studying the immune response to M. bovis . These may help to further understand the host immune response against M. bovis and to develop potential therapeutic approaches to control M. bovis infection.
    Schlagwörter Mycoplasma bovis ; immune response ; exhausted T-cell ; infection ; immune evasion ; Medicine ; R
    Thema/Rubrik (Code) 570
    Sprache Englisch
    Erscheinungsdatum 2021-03-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel: Aberrant Inter-hemispheric Connectivity in Patients With Recurrent Major Depressive Disorder: A Multimodal MRI Study.

    Zheng, Guo / Yingli, Zhang / Shengli, Chen / Zhifeng, Zhou / Bo, Peng / Gangqiang, Hou / Yingwei, Qiu

    Frontiers in neurology

    2022  Band 13, Seite(n) 852330

    Abstract: Objective: Inter-hemispheric network dysconnectivity has been well-documented in patients with recurrent major depressive disorder (MDD). However, it has remained unclear how structural networks between bilateral hemispheres relate to inter-hemispheric ... ...

    Abstract Objective: Inter-hemispheric network dysconnectivity has been well-documented in patients with recurrent major depressive disorder (MDD). However, it has remained unclear how structural networks between bilateral hemispheres relate to inter-hemispheric functional dysconnectivity and depression severity in MDD. Our study attempted to investigate the alterations in corpus callosum macrostructural and microstructural as well as inter-hemispheric homotopic functional connectivity (FC) in patients with recurrent MDD and to determine how these alterations are related with depressive severity.
    Materials and methods: Resting-state functional MRI (fMRI), T1WI anatomical images and diffusion tensor MRI of the whole brain were performed in 140 MDD patients and 44 normal controls matched for age, sex, years of education. We analyzed the macrostructural and microstructural integrity as well as voxel-mirrored homotopic functional connectivity (VMHC) of corpus callosum (CC) and its five subregion. Two-sample
    Results: Compared with control subjects, MDD patients had significantly attenuated inter-hemispheric homotopic FC in the bilateral medial prefrontal cortex, and impaired anterior CC microstructural integrity (each comparison had a corrected
    Conclusion: These findings may help to advance our understanding of the neurobiological basis of depression by identifying region-specific interhemispheric dysconnectivity.
    Sprache Englisch
    Erscheinungsdatum 2022-04-08
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2022.852330
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Cortical hierarchy disorganization in major depressive disorder and its association with suicidality.

    Shiwei, Lin / Xiaojing, Zhang / Yingli, Zhang / Shengli, Chen / Xiaoshan, Lin / Ziyun, Xu / Gangqiang, Hou / Yingwei, Qiu

    Frontiers in psychiatry

    2023  Band 14, Seite(n) 1140915

    Abstract: Objectives: To explore the suicide risk-specific disruption of cortical hierarchy in major depressive disorder (MDD) patients with diverse suicide risks.: Methods: Ninety-two MDD patients with diverse suicide risks and 38 matched controls underwent ... ...

    Abstract Objectives: To explore the suicide risk-specific disruption of cortical hierarchy in major depressive disorder (MDD) patients with diverse suicide risks.
    Methods: Ninety-two MDD patients with diverse suicide risks and 38 matched controls underwent resting-state functional MRI. Connectome gradient analysis and stepwise functional connectivity (SFC) analysis were used to characterize the suicide risk-specific alterations of cortical hierarchy in MDD patients.
    Results: Relative to controls, patients with suicide attempts (SA) had a prominent compression from the sensorimotor system; patients with suicide ideations (SI) had a prominent compression from the higher-level systems; non-suicide patients had a compression from both the sensorimotor system and higher-level systems, although it was less prominent relative to SA and SI patients. SFC analysis further validated this depolarization phenomenon.
    Conclusion: This study revealed MDD patients had suicide risk-specific disruptions of cortical hierarchy, which advance our understanding of the neuromechanisms of suicidality in MDD patients.
    Sprache Englisch
    Erscheinungsdatum 2023-04-24
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1140915
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Surfactant-Template Preparation of Polyaniline Semi-Tubes for Oxygen Reduction

    Shiming Zhang / Shengli Chen

    Catalysts, Vol 5, Iss 3, Pp 1202-

    2015  Band 1210

    Abstract: Nitrogen and metal doped nanocarbons derived from polyaniline (PANI) have been widely explored as electrocatalysts for the oxygen reduction reaction (ORR) in fuel cells. In this work, we report surfactant-template synthesis of PANI nanostructures and the ...

    Abstract Nitrogen and metal doped nanocarbons derived from polyaniline (PANI) have been widely explored as electrocatalysts for the oxygen reduction reaction (ORR) in fuel cells. In this work, we report surfactant-template synthesis of PANI nanostructures and the ORR electrocatalysts derived from them. By using cationic surfactant such as the cetyl trimethyl ammonium bromide (CTAB) as the template and the negatively charged persulfate ions as the oxidative agent to stimulate the aniline polymerization in the micelles of CTAB, PANI with a unique 1-D semi-tubular structure can be obtained. The semi-tubular structure can be maintained even after high-temperature treatment at 900 °C, which yields materials exhibiting promising ORR activity.
    Schlagwörter polyaniline ; cetyl trimethyl ammonium bromide ; micelle ; semi-tubes ; oxygen reduction reaction ; Chemical technology ; TP1-1185 ; Chemistry ; QD1-999
    Sprache Englisch
    Erscheinungsdatum 2015-07-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
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