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  1. Article: Effects of sulfur dioxide on growth, photosynthesis and enzyme activities of Chinese Guger-Tree seedlings.

    Sheu, B H

    Environmental pollution (Barking, Essex : 1987)

    2004  Volume 86, Issue 3, Page(s) 349–354

    Abstract: The Chinese Guger-Tree (Schima superba Gard et Champ var. superba) is an important harwood species in Taiwan where the ambient SO(2) concentration in some areas is high. Seedlings were raised in field chambers with and without SO(2) to determine whether ... ...

    Abstract The Chinese Guger-Tree (Schima superba Gard et Champ var. superba) is an important harwood species in Taiwan where the ambient SO(2) concentration in some areas is high. Seedlings were raised in field chambers with and without SO(2) to determine whether this species is affected by this pollutant. After 4 weeks of exposure to 325 ppb of SO(2), the photosynthetic rate of seedlings decreased immediately. During the fumigation period, stem height growth was not inhibited, however, the stem diameter growth was reduced significantly. The dry weight of leaves was unchanged, while stem, root and total seedling weight were lower than those of control plants. Sulfhydryl groups in leaves increased by 75%, whereas they did not change in roots following SO(2) uptake. Superoxide dismutase in leaves did not change, however, peroxidase activity increased significantly. Results suggest that ambient SO(2) in some areas in Taiwan may affect the physiology and growth of the Chinese Guger-Tree.
    Language English
    Publishing date 2004-05-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0269-7491 ; 0013-9327
    ISSN (online) 1873-6424
    ISSN 0269-7491 ; 0013-9327
    DOI 10.1016/0269-7491(94)90176-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comparison of Conventional TNM and Novel TNMB Staging Systems for Non-Small Cell Lung Cancer.

    Haro, Greg J / Sheu, Bonnie / Cook, Nancy R / Woodard, Gavitt A / Mann, Michael J / Kratz, Johannes R

    JAMA network open

    2019  Volume 2, Issue 12, Page(s) e1917062

    Abstract: Importance: Improved staging for non-small cell lung cancer (NSCLC) represents a critical unmet need. External validations of the eighth edition of the TNM staging system have yielded disappointing results, with persistently high mortality observed in ... ...

    Abstract Importance: Improved staging for non-small cell lung cancer (NSCLC) represents a critical unmet need. External validations of the eighth edition of the TNM staging system have yielded disappointing results, with persistently high mortality observed in early-stage disease.
    Objective: To determine whether incorporation of a molecular prognostic classifier into conventional TNM staging for NSCLC improves estimation of disease-free survival.
    Design, setting, and participants: This cohort study was conducted at an academic, quaternary care medical center from 2012 to 2018. A consecutive series of 238 patients underwent surgical resection of stage I to IIIC nonsquamous NSCLC and had molecular prognostic classifier testing performed. Data analysis was conducted in May 2019.
    Exposures: Patients were restaged according to the seventh and eighth editions of the TNM staging system and the novel TMMB staging system, which maintains the order and structure of the eighth edition of the TNM but downstages or upstages according to low or high molecular risk, respectively.
    Main outcomes and measures: The primary outcome was disease-free survival 3 years from the time of surgical resection. Reclassification statistics were then used to evaluate performance and improvement measures of the TNM seventh and eighth editions and the TNMB staging system.
    Results: Two hundred thirty-eight patients (144 [60.5%] female; median [interquartile range] age, 70 [63-75] years) were analyzed. The median (interquartile range) follow-up was 25 (14-40) months, and the disease-free survival rate was estimated to be 58.3% (95% CI, 45.7% to 69.0%). One hundred fifty-nine patients (66.8%) were reclassified by the TNMB staging system. Overall model fit remained the same for the seventh and eighth editions of the TNM staging system, whereas the R2 statistic (change from 0.22 to 0.31), concordance index (change from 0.68 to 0.73), and log-rank χ2 (change from 38 to 108) were all associated with improvements after TNMB adoption. The TNMB system, compared with the TNM eighth edition, was associated with enhanced identification of high-risk patients and better differentiation of those without recurrence from those who had recurrence (net reclassification improvement, 0.28; 95% CI, 0.08 to 0.46; P < .001), whereas the eighth edition compared with the seventh edition was not associated with improvement of this measure (net reclassification improvement, 0.02; 95% CI, -0.18 to 0.21; P = .87).
    Conclusions and relevance: The TNMB staging system was associated with improved estimation of disease-free survival compared with conventional TNM staging. Incorporation of a molecular prognostic classifier into staging for NSCLC may lead to better identification of high-risk patients.
    MeSH term(s) Aged ; Carcinoma, Non-Small-Cell Lung/diagnosis ; Carcinoma, Non-Small-Cell Lung/mortality ; Cohort Studies ; Disease-Free Survival ; Female ; Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/mortality ; Male ; Middle Aged ; Neoplasm Staging/methods ; Prognosis ; Survival Rate
    Language English
    Publishing date 2019-12-02
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2019.17062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Perioperative Lung Resection Outcomes After Implementation of a Multidisciplinary, Evidence-based Thoracic ERAS Program.

    Haro, Greg J / Sheu, Bonnie / Marcus, Sivan G / Sarin, Ankit / Campbell, Lundy / Jablons, David M / Kratz, Johannes R

    Annals of surgery

    2019  Volume 274, Issue 6, Page(s) e1008–e1013

    Abstract: Objective: This prospective study evaluated perioperative lung resection outcomes after implementation of a multidisciplinary, evidence-based Thoracic Enhanced Recovery After Surgery (ERAS) Program in an academic, quaternary-care center.: Background: ...

    Abstract Objective: This prospective study evaluated perioperative lung resection outcomes after implementation of a multidisciplinary, evidence-based Thoracic Enhanced Recovery After Surgery (ERAS) Program in an academic, quaternary-care center.
    Background: ERAS programs have the potential to improve outcomes, but have not been widely utilized in thoracic surgery.
    Methods: In all, 295 patients underwent elective lung resection for pulmonary malignancy from 2015 to 2019 PRE (n = 169) and POST (n = 126) implementation of an ERAS program containing all major ERAS Society guidelines. Propensity score-matched analysis, based upon patient, tumor, and surgical characteristics, was utilized to evaluate outcomes.
    Results: After ERAS implementation, there was increased minimally invasive surgery (PRE 39.6%→POST 62.7%), reduced intensive care unit utilization (PRE 70.4%→POST 21.4%), improved chest tube (PRE 24.3%→POST 54.8%) and urinary catheter (PRE 20.1%→POST 65.1%) removal by postoperative day 1, and increased ambulation ≥3× on postoperative day 1 (PRE 46.8%→POST 54.8%). Propensity score-matched analysis that accounted for minimally invasive surgery demonstrated that program implementation reduced length of stay by 1.2 days [95% confidence interval (CI) 0.3-2.0; PRE 4.4→POST 3.2), morbidity by 12.0% (95% CI 1.6%-22.5%; PRE 32.0%→POST 20.0%), opioid use by 19 oral morphine equivalents daily (95% CI 1-36; PRE 101→POST 82), and the direct costs of surgery and hospitalization by $3500 (95% CI $1100-5900; PRE $23,000→POST $19,500). Despite expedited discharge, readmission remained unchanged (PRE 6.3%→POST 6.6%; P = 0.94).
    Conclusions: The Thoracic ERAS Program for lung resection reduced length of stay, morbidity, opioid use, and direct costs without change in readmission. This is the first external validation of the ERAS Society thoracic guidelines; adoption by other centers may show similar benefit.
    MeSH term(s) Aged ; Analgesics, Opioid/therapeutic use ; Cost Control ; Enhanced Recovery After Surgery ; Evidence-Based Medicine ; Female ; Humans ; Length of Stay/statistics & numerical data ; Lung Neoplasms/mortality ; Lung Neoplasms/surgery ; Male ; Minimally Invasive Surgical Procedures ; Patient Readmission/statistics & numerical data ; Practice Guidelines as Topic ; Propensity Score ; Prospective Studies ; Pulmonary Surgical Procedures/methods ; Pulmonary Surgical Procedures/mortality
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2019-12-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000003719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Giving patients privacy in the pharmacy.

    Sheu, B J

    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

    1998  Volume 55, Issue 21, Page(s) 2245–2246

    MeSH term(s) Confidentiality ; Humans ; Pharmacy ; Privacy ; Telephone
    Language English
    Publishing date 1998-11-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1224627-x
    ISSN 1079-2082
    ISSN 1079-2082
    DOI 10.1093/ajhp/55.21.2245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A Giant Gastric Ulcer Caused by Mucormycosis Infection In a Patient with Renal Transplantation

    Sheu, B.-S. / Lee, P.-C. / Yang, H.-B.

    Endoscopy

    2008  Volume 30, Issue 05, Page(s) S 60–S 61

    Language English
    Publishing date 2008-03-17
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-2007-1001327
    Database Thieme publisher's database

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  6. Article ; Online: Diffuse intramural duodenal hematoma complicated by lethal necrotizing pancreatitis after endoscopic duodenal biopsy.

    Chen, P S / Cheng, H C / Sheu, B S

    Endoscopy

    2008  Volume 40 Suppl 2, Page(s) E143

    MeSH term(s) Abdominal Pain/diagnosis ; Adolescent ; Biopsy, Needle/adverse effects ; Disease Progression ; Duodenoscopy/adverse effects ; Duodenoscopy/methods ; Fatal Outcome ; Graft vs Host Disease/diagnosis ; Graft vs Host Disease/etiology ; Hematoma/diagnostic imaging ; Hematoma/etiology ; Hematoma/physiopathology ; Hematopoietic Stem Cell Transplantation/adverse effects ; Hematopoietic Stem Cell Transplantation/methods ; Hodgkin Disease/diagnosis ; Hodgkin Disease/surgery ; Humans ; Male ; Pancreatitis, Acute Necrotizing/etiology ; Pancreatitis, Acute Necrotizing/physiopathology ; Severity of Illness Index ; Tomography, X-Ray Computed ; Transplantation, Autologous
    Language English
    Publishing date 2008-09
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-2007-995736
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Leukocyte membrane bleb and pseudopod formation in hypertension.

    Edwards, K M / Sheu, B / Hong, S / Penn, A H / Schmid-Schönbein, G W / Mills, P J

    Journal of human hypertension

    2010  Volume 24, Issue 10, Page(s) 684–686

    MeSH term(s) Adult ; Apoptosis ; Blood Pressure ; Case-Control Studies ; Cell Membrane/pathology ; Female ; Humans ; Hypertension/pathology ; Hypertension/physiopathology ; Leukocytes/pathology ; Male ; Middle Aged ; Pseudopodia/pathology
    Language English
    Publishing date 2010-04-22
    Publishing country England
    Document type Letter ; Research Support, N.I.H., Extramural
    ZDB-ID 639472-3
    ISSN 1476-5527 ; 0950-9240
    ISSN (online) 1476-5527
    ISSN 0950-9240
    DOI 10.1038/jhh.2010.41
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Combining Endoscopy with DICIDA Scanning to Evaluate Prolonged Epigastralgia After Choledochoduodenostomy

    Sheu, B.-S. / Lin, P.-W. / Lin, X.-Z. / Lin, C.-Y.

    Endoscopy

    2008  Volume 27, Issue 09, Page(s) 708–709

    Language English
    Publishing date 2008-03-17
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-2007-1005795
    Database Thieme publisher's database

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  9. Article ; Online: Nutrition therapy in esophageal cancer-Consensus statement of the Gastroenterological Society of Taiwan.

    Chen, M-J / Wu, I-C / Chen, Y-J / Wang, T-E / Chang, Y-F / Yang, C-L / Huang, W-C / Chang, W-K / Sheu, B-S / Wu, M-S / Lin, J-T / Chu, C-H

    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    2018  Volume 31, Issue 8

    Abstract: A number of clinical guidelines on nutrition therapy in cancer patients have been published by national and international societies; however, most of the reviewed data focused on gastrointestinal cancer or non-cancerous abdominal surgery. To collate the ... ...

    Abstract A number of clinical guidelines on nutrition therapy in cancer patients have been published by national and international societies; however, most of the reviewed data focused on gastrointestinal cancer or non-cancerous abdominal surgery. To collate the corresponding data for esophageal cancer (EC), a consensus panel was convened to aid specialists from different disciplines, who are involved in the clinical nutrition care of EC patients. The literature was searched using MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, and the ISI Web of Knowledge. We searched for the best evidence pertaining to nutrition therapy in the case of EC. The panel summarized the findings in 3 sections of this consensus statement, based on which, after the diagnosis of EC, an initial distinction is made between the patients, as follows: (1) Assessment; (2) Therapy in patients with resectable disease; patients receiving chemotherapy or chemoradiotherapy prior to resection, and patients with unresectable disease, requiring chemoradiotherapy or palliative therapy; and (3) Formula. The resulting consensus statement reflects the opinions of a multidisciplinary group of experts, and a review of the current literature, and outlines the essential aspects of nutrition therapy in the case of EC. The statements are: Patients with EC are among one of the highest risk to have malnutrition. Patient generated suggestive global assessment is correlated with performance status and prognosis. Nutrition assessment for patients with EC at the diagnosis, prior to definitive therapy and change of treatment strategy are suggested and the timing interval can be two weeks during the treatment period, and one month while the patient is stable. Patients identified as high risk of malnutrition should be considered for preoperative nutritional support (tube feeding) for at least 7-10 days. Various routes for tube feedings are available after esophagectomy with similar nutrition support benefits. Limited intrathoracic anastomotic leakage postesophagectomy can be managed with intravenous antibiotics and self-expanding metal stent (SEMS) or jejunal tube. Enteral nutrition in patients receiving preoperative chemotherapy or chemoradiation provides benefits of maintaining weight, decreasing toxicity, and preventing treatment interruption. Tube feeding or SEMS can offer nutrition support in patients with unresectable esophageal cancer, but SEMS is not recommended for those with neoadjuvant chemoradiation before surgery. Enteral immunonutrition may preserve lean body mass and attenuates stress response after esophagectomy. Administration of glutamine may decrease the severity of chemotherapy induced mucositis. Enteral immunonutrition achieves greater nutrition status or maintains immune functions during concurrent chemoradiation.
    MeSH term(s) Consensus ; Esophageal Neoplasms/therapy ; Gastroenterology ; Humans ; Nutritional Support/methods ; Societies, Medical ; Taiwan ; Treatment Outcome
    Language English
    Publishing date 2018-06-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 639470-x
    ISSN 1442-2050 ; 1120-8694
    ISSN (online) 1442-2050
    ISSN 1120-8694
    DOI 10.1093/dote/doy016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Helicobacter pylori infection in hemodialysis patients.

    Sheu, B S / Huang, J J

    The International journal of artificial organs

    2001  Volume 24, Issue 10, Page(s) 669–670

    MeSH term(s) Helicobacter Infections/epidemiology ; Helicobacter Infections/etiology ; Helicobacter pylori ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/epidemiology ; Mass Screening ; Renal Dialysis/statistics & numerical data ; Taiwan/epidemiology
    Language English
    Publishing date 2001-10
    Publishing country Italy
    Document type Editorial
    ZDB-ID 80456-3
    ISSN 1724-6040 ; 0391-3988
    ISSN (online) 1724-6040
    ISSN 0391-3988
    Database MEDical Literature Analysis and Retrieval System OnLINE

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