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  1. AU="Shewade, Hemant Deepak"
  2. AU="Ninic, Sanja"
  3. AU="Nitta, Takashi"
  4. AU="Catanesi, M. G."
  5. AU="Kim, E. J."
  6. AU="De, Yanyan"
  7. AU="Zheng-Yan, Gao"
  8. AU="Carvajal-Maldonado, Denisse"
  9. AU="Gallagher, Julia E"
  10. AU="Skelin, Ivan"
  11. AU="Pinarli, Faruk Güçlü"
  12. AU=Carmina E
  13. AU=Abi-Rafeh Jad
  14. AU="Jalil, Yorschua F"
  15. AU="Barber, M"
  16. AU="Ritt, Luiz Eduardo Fonteles"
  17. AU="Qiu, Jiajing"
  18. AU=Wang Heping
  19. AU="Miyazaki, Masashi"
  20. AU="R Kulkarni"
  21. AU="Braga, D."
  22. AU="Mwenda, Mulenga"
  23. AU="Li, Baohua"
  24. AU="Zhang, Nasen Jonathan"
  25. AU="Scotlandi, Katia"
  26. AU="Thomson, M A"
  27. AU=New Sophie E P
  28. AU="Fenrich, Craig A"
  29. AU="Staehelin, Cornelia"
  30. AU="Akhtar, Suraiya"
  31. AU="Georgel, Philippe"
  32. AU="Gruenewald, Leon D"
  33. AU="Charron, Morgane"
  34. AU="Leona S. Alizadeh" AU="Leona S. Alizadeh"
  35. AU="Soriano, Stéphane"
  36. AU="Lin, Pao-Yen"
  37. AU="Mudali, Gayathri"
  38. AU="McElveen, John T"
  39. AU="Kraimps, Jean-Louis"
  40. AU="Patel, Sheila K"
  41. AU="Zian, Zeineb"
  42. AU="Langley, Jonathan"
  43. AU="Bell, Thomas G."
  44. AU="Harris, Charles"
  45. AU="Lai, Renfa"
  46. AU="Sakane, Tatsuya"
  47. AU="Mirza, I."
  48. AU="Beatriz Amorim Beltrão"
  49. AU="Wildman, D"
  50. AU="Manghi, Manoel"
  51. AU="van Dinther, Maarten"
  52. AU="Adams, Ashley L"
  53. AU="Zhang, Er-Bin"
  54. AU="Diuk-Wasser, Maria A"
  55. AU="Chowdhury, Muhtamim"
  56. AU="Rivas, Manuel A"
  57. AU="Mangelis, Anastasios"
  58. AU="Simpson, Tina Y"
  59. AU="Li, Peirang"
  60. AU="Zhang, Zhao-Liang"
  61. AU="Perner, Sven"
  62. AU=Suwanwongse Kulachanya AU=Suwanwongse Kulachanya
  63. AU="Rose, Jacqueline"
  64. AU="E Lostis"

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  1. Artikel ; Online: How can TB Mukt Panchayat initiative contribute towards ending tuberculosis in India?

    Njarekkattuvalappil, Swathi Krishna / Shewade, Hemant Deepak / Sharma, Parth / Bhat Suseela, Rakesh Purushothama / Sharma, Nandini

    The Lancet regional health. Southeast Asia

    2024  Band 24, Seite(n) 100376

    Abstract: Community Engagement (CE) for disease control and health has been tested for a long time across the globe for various health programmes. Realizing the need for true multisectoral action and CE and ownership for ending TB on an accelerated timeline, the ... ...

    Abstract Community Engagement (CE) for disease control and health has been tested for a long time across the globe for various health programmes. Realizing the need for true multisectoral action and CE and ownership for ending TB on an accelerated timeline, the Government of India launched a nationwide campaign for 'TB
    Sprache Englisch
    Erscheinungsdatum 2024-03-22
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ISSN 2772-3682
    ISSN (online) 2772-3682
    DOI 10.1016/j.lansea.2024.100376
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: The potential impact of the COVID-19 response related lockdown on TB incidence and mortality in India.

    Bhargava, Anurag / Shewade, Hemant Deepak

    The Indian journal of tuberculosis

    2020  Band 67, Heft 4S, Seite(n) S139–S146

    Abstract: India has the highest burden of incident tuberculosis (TB) cases and deaths globally. TB is strongly associated with poverty and this risk is largely mediated by undernutrition in India. COVID-19 response related lockdown has resulted in an economic ... ...

    Abstract India has the highest burden of incident tuberculosis (TB) cases and deaths globally. TB is strongly associated with poverty and this risk is largely mediated by undernutrition in India. COVID-19 response related lockdown has resulted in an economic crisis which may double levels of poverty, has exacerbated food insecurity, and disrupted TB services. These developments may have serious implications for TB progression and transmission in India. The nutritional status of a population is a strong determinant of the TB incidence, and undernutrition in adults alone accounts for 32-44% of TB incidence in India. A systematic review has shown that a 14% increase in TB incidence can occur per one unit decrease in body mass index (BMI), across the BMI range of 18.5-30 kg/m2. We believe that one unit decrease in BMI (corresponding to a 2-3 kg weight loss) may result in the poor in India as a result of the lockdown and its aftermath. This may result in an increase in estimated (uncertainty interval) incident TB by 185 610 (180 230, 190 990) cases. A 59% reduction in TB case detection between end March and May 2020, may result in an estimated (uncertainty interval) additional 87 711 (59 998, 120 630) TB deaths [19.5% increase (14.5, 24.7)] in 2020. Disadvantaged social groups and those living in states with higher levels of poverty, under-nutrition,and migrant workers are at particular risk. We suggest enhanced rations including pulses through the public distribution system and direct cash transfers to the poor pending restoration of livelihoods. TB services should be resumed immediately with enhanced efforts at case detection including active case finding. To prevent deaths among TB detected within the national TB programme, systemic identification, referral and management of severe disease at notification should be considered.
    Mesh-Begriff(e) Adult ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/transmission ; Communicable Disease Control ; Health Services Accessibility ; Humans ; Incidence ; India/epidemiology ; Nutritional Status ; SARS-CoV-2 ; Tuberculosis/diagnosis ; Tuberculosis/epidemiology ; Tuberculosis/therapy
    Sprache Englisch
    Erscheinungsdatum 2020-07-10
    Erscheinungsland India
    Dokumenttyp Journal Article ; Review
    ZDB-ID 603129-8
    ISSN 0019-5707 ; 0019-5705
    ISSN 0019-5707 ; 0019-5705
    DOI 10.1016/j.ijtb.2020.07.004
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: The potential impact of the COVID-19 response related lockdown on TB incidence and mortality in India

    Bhargava, Anurag / Shewade, Hemant Deepak

    Indian J. Tuberc.

    Abstract: India has the highest burden of incident tuberculosis (TB) cases and deaths globally. TB is strongly associated with poverty and this risk is largely mediated by undernutrition in India. COVID-19 response related lockdown has resulted in an economic ... ...

    Abstract India has the highest burden of incident tuberculosis (TB) cases and deaths globally. TB is strongly associated with poverty and this risk is largely mediated by undernutrition in India. COVID-19 response related lockdown has resulted in an economic crisis which may double levels of poverty, has exacerbated food insecurity, and disrupted TB services. These developments may have serious implications for TB progression and transmission in India. The nutritional status of a population is a strong determinant of the TB incidence, and undernutrition in adults alone accounts for 32–44% of TB incidence in India. A systematic review has shown that a 14% increase in TB incidence can occur per one unit decrease in body mass index (BMI), across the BMI range of 18.5–30 kg/m2. We believe that one unit decrease in BMI (corresponding to a 2–3 kg weight loss) may result in the poor in India as a result of the lockdown and its aftermath. This may result in an increase in estimated (uncertainty interval) incident TB by 185 610 (180 230, 190 990) cases. A 59% reduction in TB case detection between end March and May 2020, may result in an estimated (uncertainty interval) additional 87 711 (59 998, 120 630) TB deaths [19.5% increase (14.5, 24.7)] in 2020. Disadvantaged social groups and those living in states with higher levels of poverty, under-nutrition,and migrant workers are at particular risk. We suggest enhanced rations including pulses through the public distribution system and direct cash transfers to the poor pending restoration of livelihoods. TB services should be resumed immediately with enhanced efforts at case detection including active case finding. To prevent deaths among TB detected within the national TB programme, systemic identification, referral and management of severe disease at notification should be considered.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #639943
    Datenquelle COVID19

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  4. Artikel ; Online: The potential impact of the COVID-19 response related lockdown on TB incidence and mortality in India

    Bhargava, Anurag / Shewade, Hemant Deepak

    Indian Journal of Tuberculosis ; ISSN 0019-5707

    2020  

    Schlagwörter Infectious Diseases ; covid19
    Sprache Englisch
    Verlag Elsevier BV
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    DOI 10.1016/j.ijtb.2020.07.004
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

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  5. Artikel: Does active case finding for tuberculosis generate more false-positives compared to passive case finding in India?

    Shewade, Hemant Deepak / Satyanarayana, Srinath / Kumar, Ajay Mv

    The Indian journal of tuberculosis

    2020  Band 68, Heft 3, Seite(n) 396–399

    Mesh-Begriff(e) Humans ; India/epidemiology ; Tuberculosis/diagnosis ; Tuberculosis/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2020-09-17
    Erscheinungsland India
    Dokumenttyp Letter ; Comment
    ZDB-ID 603129-8
    ISSN 0019-5707 ; 0019-5705
    ISSN 0019-5707 ; 0019-5705
    DOI 10.1016/j.ijtb.2020.09.012
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Adjusting Reported COVID-19 Deaths for the Prevailing Routine Death Surveillance in India.

    Shewade, Hemant Deepak / Parameswaran, Giridara Gopal / Mazumder, Archisman / Gupta, Mohak

    Frontiers in public health

    2021  Band 9, Seite(n) 641991

    Abstract: In India, the "low mortality" narrative based on the reported COVID-19 deaths may be causing more harm than benefit. The extent to which COVID-19 deaths get reported depends on the coverage of routine death surveillance [death registration along with ... ...

    Abstract In India, the "low mortality" narrative based on the reported COVID-19 deaths may be causing more harm than benefit. The extent to which COVID-19 deaths get reported depends on the coverage of routine death surveillance [death registration along with medical certification of cause of death (MCCD)] and the errors in MCCD. In India, the coverage of routine death surveillance is 18.1%. This is compounded by the fact that COVID-19 death reporting is focused among reported cases and the case detection ratio is low. To adjust for the coverage of routine death surveillance and errors in MCCD, we calculated a correction (multiplication) factor at national and state level to produce an estimated number of COVID-19 deaths. As on July 31, 2020, we calculated the infection fatality ratio (IFR) for India (0.58:100-1.16:100) using these estimated COVID-19 deaths; this is comparable with the IFR range in countries with near perfect routine death surveillance. We recommend the release of excess deaths data during COVID-19 (at least in states with high death registration) and post-mortem COVID-19 testing as a surveillance activity for a better understanding of under-reporting. In its absence, we should adjust reported COVID-19 deaths for the coverage of routine death surveillance and errors in MCCD. This way we will have a clear idea of the true burden of deaths and our public health response will never be inadequate. We recommend that "reported" or "estimated" is added before the COVID-19 death data and related indicators for better clarity and interpretation.
    Mesh-Begriff(e) COVID-19 ; COVID-19 Testing ; Humans ; India/epidemiology ; Public Health ; SARS-CoV-2
    Sprache Englisch
    Erscheinungsdatum 2021-08-05
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2021.641991
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Poor adherence to TB diagnosis guidelines among under-five children with severe acute malnutrition in central India: A missed window of opportunity?

    Singh, Akash Ranjan / Kumar, Amber / Shewade, Hemant Deepak / Dhingra, Bhavna

    PloS one

    2021  Band 16, Heft 3, Seite(n) e0248192

    Abstract: Background: In India, under-five children with Severe Acute Malnutrition (SAM) are referred to Nutritional Rehabilitation Centers (NRCs). NRCs screen the causes of SAM including tuberculosis (TB). The national TB programme recommends upfront testing ... ...

    Abstract Background: In India, under-five children with Severe Acute Malnutrition (SAM) are referred to Nutritional Rehabilitation Centers (NRCs). NRCs screen the causes of SAM including tuberculosis (TB). The national TB programme recommends upfront testing with a rapid molecular test if TB is suspected in children.
    Objective: We estimated the yield of and adherence to the TB diagnostic guidelines (clinical assessment and assessment for microbiological confirmation) among under-five children with SAM admitted at NRCs (six in district Sagar and four in district Sheopur) of Madhya Pradesh, India in 2017. We also explored the challenges in screening from the health care providers' perspective.
    Methods: It was an explanatory mixed method study. The NRC records were reviewed This was followed by three key informant interviews and three focus group discussions among staff of NRC and TB programme. Manual descriptive thematic analysis was performed.
    Results: Of 3230, a total of 2665(83%) children underwent Mantoux test, 2438(75%) underwent physical examination, 2277(70%) were asked about the symptoms suggestive of TB, 1220(38%) underwent chest radiograph and 485(15%) were asked for recent contact with TB. A total of 547(17%) underwent assessment for microbiological confirmation. Of 547, a total of 229 gastric aspirate specimens underwent rapid molecular test (24% positive) and 318 underwent sputum microscopy (44% positive). A total of 223 were diagnosed as TB (195 microbiologically and 28 clinically confirmed) and 209 were initiated on anti-TB treatment. The treatment outcome was favourable (cure or treatment completed) for 70(31%) and not recorded for 121(54%). The main perceived challenges in screening for TB were poor team skills, lack of diagnostic facilities and poor understanding of the guidelines due to inadequate training.
    Conclusion: Though NRCs provided a unique window of opportunity for the screening and management of TB among under-five children with SAM, the utilization of this opportunity remained suboptimal.
    Mesh-Begriff(e) Child, Preschool ; Female ; Guideline Adherence ; Humans ; India ; Infant ; Male ; Severe Acute Malnutrition/complications ; Tuberculosis/complications ; Tuberculosis/diagnosis
    Sprache Englisch
    Erscheinungsdatum 2021-03-12
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0248192
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Effectiveness and safety of Levofloxacin containing regimen in the treatment of Isoniazid mono-resistant pulmonary Tuberculosis: a systematic review.

    Inbaraj, Leeberk Raja / Shewade, Hemant Deepak / Daniel, Jefferson / Srinivasalu, Vignes Anand / Paul, Jabez / Satish, S / Kirubakaran, Richard / Padmapriyadarsini, Chandrasekaran

    Frontiers in medicine

    2023  Band 10, Seite(n) 1085010

    Abstract: Background: We aimed to determine the effectiveness and safety of the Levofloxacin-containing regimen that the World Health Organization is currently recommending for the treatment of Isoniazid mono-resistant pulmonary Tuberculosis.: Methods: Our ... ...

    Abstract Background: We aimed to determine the effectiveness and safety of the Levofloxacin-containing regimen that the World Health Organization is currently recommending for the treatment of Isoniazid mono-resistant pulmonary Tuberculosis.
    Methods: Our eligible criteria for the studies to be included were; randomized controlled trials or cohort studies that focused on adults with Isoniazid mono-resistant tuberculosis (HrTB) and treated with a Levofloxacin-containing regimen along with first-line anti-tubercular drugs; they should have had a control group treated with first-line without Levofloxacin; should have reported treatment success rate, mortality, recurrence, progression to multidrug-resistant Tuberculosis. We performed the search in MEDLINE, EMBASE, Epistemonikos, Google Scholar, and Clinical trials registry. Two authors independently screened the titles/abstracts and full texts that were retained after the initial screening, and a third author resolved disagreements.
    Results: Our search found 4,813 records after excluding duplicates. We excluded 4,768 records after screening the titles and abstracts, retaining 44 records. Subsequently, 36 articles were excluded after the full-text screening, and eight appeared to have partially fulfilled the inclusion criteria. We contacted the respective authors, and none responded positively. Hence, no articles were included in the meta-analysis.
    Conclusion: We found no "quality" evidence currently on the effectiveness and safety of Levofloxacin in treating HrTB.
    Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022290333, identifier: CRD42022290333.
    Sprache Englisch
    Erscheinungsdatum 2023-06-20
    Erscheinungsland Switzerland
    Dokumenttyp Systematic Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1085010
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Assessing the implementation of a mobile App-based electronic health record: A mixed-method study from South India.

    Shilpa, D M / Naik, Poonam Ramesh / Shewade, Hemant Deepak / Sudarshan, H

    Journal of education and health promotion

    2020  Band 9, Seite(n) 102

    Abstract: Background: Government of India recognizes the use of "information, communication, and technology" in the provision of comprehensive primary healthcare. In 2014-2015, Karuna Trust, a nongovernmental organization, Bengaluru, India, introduced an ... ...

    Abstract Background: Government of India recognizes the use of "information, communication, and technology" in the provision of comprehensive primary healthcare. In 2014-2015, Karuna Trust, a nongovernmental organization, Bengaluru, India, introduced an electronic health record (EHR) innovation, namely "Comprehensive Public Health Management" application (CPHM App). Data could be entered in an offline mode followed by syncing with cloud. The CPHM App was piloted in primary health center (PHC) Gumballi, in Karnataka, with focus on household survey and maternal and child health (MCH) services.
    Objectives: To compare the consistency of selected MCH process indicators for Health Management Information System [HMIS] available from paper-based records and those generated through the CPHM App (2016-2017). We also explored the implementation enablers, barriers, and suggested solutions from the user perspective.
    Methods: A sequential mixed-method study design was followed. Quantitative phase involved aggregate data analysis looking into the consistency of selected MCH process indicators available from paper-based records and those generated through the CPHM App (2016-2017) followed by thematic analysis of in-depth interviews of healthcare providers. Consistency was defined as a percentage where the numerator was the HMIS-related process indicator data from CPHM App and denominator was the data from paper-based records.
    Results: Three out of 12 selected MCH indicators had consistency of >80%. The quarterly consistency reduced over the 2 years. Dual burden of entry and regular monitoring of paper-based records by district health and family welfare department were the reasons why more importance was given to entry in paper-based records. Ability to generate aggregate indicators with CPHM App, easy to use and retrieve data in the field, and reminder facility for planned health activities were some of the factors facilitating CPHM implementation. The key barriers were limited technical expertise and support from the technical team and no internet connectivity in the field and traveling to PHC to sync the data. Provision of real-time technical support and availability of data connectivity in the field were some of the solutions suggested.
    Conclusion: There should be a minimum of 1-2 years of simultaneous use of EHR and paper-based records after which one must shift to EHR.
    Sprache Englisch
    Erscheinungsdatum 2020-04-28
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2715449-X
    ISSN 2319-6440 ; 2277-9531
    ISSN (online) 2319-6440
    ISSN 2277-9531
    DOI 10.4103/jehp.jehp_749_19
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Cervical Cancer Care Continuum in South India: Evidence from a Community-based Screening Program.

    Vidhubala, E / Niraimathi, K / Shewade, Hemant Deepak / Mahadevan, Sankar

    Journal of epidemiology and global health

    2020  Band 10, Heft 1, Seite(n) 28–35

    Abstract: In India, cervical cancer screening is conducted at various levels; however, after screening, the adherence to the cancer care continuum is barely understood. This study evaluated a community-based cancer screening program conducted in a rural setting ( ... ...

    Abstract In India, cervical cancer screening is conducted at various levels; however, after screening, the adherence to the cancer care continuum is barely understood. This study evaluated a community-based cancer screening program conducted in a rural setting (Tirunelveli and Tuticorin districts) in South India and reviewed the completion of care continuum. In this longitudinal descriptive study involving secondary data collection, data from the case records of 2192 women who were consecutively screened between March 2015 and May 2016 were included. All women underwent conventional cytology-based screening (Pap smear) and Visual Inspection with Acetic Acid (VIA). Those for whom either test was positive were referred for histopathological confirmation. Patients with confirmed precancerous conditions and unsatisfactory Pap smears were referred for further management. In total, 2192 women were screened [age range, 17-69 years; mean (standard deviation), 39.2 (8.5)]. Common symptom and sign were white discharge per vaginum (34.9%) and cervical erosion (34.4%), respectively. The VIA was positive for 24% (523/2178; 14 women did not cooperate for VIA) and 113 (5.1%) had epithelial cell abnormality in the Pap smear test. Per histopathology findings, one woman had non-keratinizing squamous cell carcinoma. Seven, three, and four had cervical intraepithelial neoplasia I, II and III, respectively. Of 2192, 807 were eligible for referral (597 had positive results on either Pap or VIA). Among the 807 women referred, only 74 (9.2%) women visited the referral center. The follow-up rate was very poor accounting to fragmentation of care continuum. The success of the screening program depends on the completion of the care continuum.
    Mesh-Begriff(e) Adult ; Aged ; Aged, 80 and over ; Community Health Services/statistics & numerical data ; Continuity of Patient Care/statistics & numerical data ; Early Detection of Cancer/statistics & numerical data ; Female ; Humans ; India/epidemiology ; Middle Aged ; Rural Population/statistics & numerical data ; Treatment Adherence and Compliance/statistics & numerical data ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/epidemiology ; Uterine Cervical Neoplasms/therapy ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2020-02-21
    Erscheinungsland France
    Dokumenttyp Journal Article
    ZDB-ID 2645324-1
    ISSN 2210-6014 ; 2210-6014
    ISSN (online) 2210-6014
    ISSN 2210-6014
    DOI 10.2991/jegh.k.191111.001
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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