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  1. Article ; Online: Development and validation of Chinese compensatory health beliefs scale.

    Shi, Hua Yu / Zhang, Ya Ru

    Frontiers in public health

    2024  Volume 12, Page(s) 1271409

    Abstract: Compensatory Health Beliefs (CHBs), the notion that healthy behaviors can offset the negative effects of unhealthy actions, have been widely explored in Western contexts. Yet, their relevance within the Chinese cultural milieu remains underexplored. The ... ...

    Abstract Compensatory Health Beliefs (CHBs), the notion that healthy behaviors can offset the negative effects of unhealthy actions, have been widely explored in Western contexts. Yet, their relevance within the Chinese cultural milieu remains underexplored. The primary objective of this research was to develop and validate a Chinese version of the CHBs scale (CHBs-C), addressing the gap in the literature regarding the applicability of CHBs within the Chinese cultural context. A multi-stage translation (from English to Chinese) was first completed, and exploratory factor analysis was conducted (
    MeSH term(s) Humans ; Female ; Male ; Reproducibility of Results ; Adult ; Surveys and Questionnaires/standards ; Health Behavior ; China ; Factor Analysis, Statistical ; Psychometrics ; Middle Aged ; Health Knowledge, Attitudes, Practice ; Young Adult ; Adolescent ; Translations
    Language English
    Publishing date 2024-04-23
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Validation Study
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2024.1271409
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Inactivated recombinant influenza vaccine: the promising direction for the next generation of influenza vaccine.

    Shi, Hua / Ross, Ted M

    Expert review of vaccines

    2024  Volume 23, Issue 1, Page(s) 409–418

    Abstract: Introduction: Vaccination is the most effective method to control the prevalence of seasonal influenza and the most widely used influenza vaccine is the inactivated influenza vaccine (IIV). Each season, the influenza vaccine must be updated to be most ... ...

    Abstract Introduction: Vaccination is the most effective method to control the prevalence of seasonal influenza and the most widely used influenza vaccine is the inactivated influenza vaccine (IIV). Each season, the influenza vaccine must be updated to be most effective against current circulating variants. Therefore, developing a universal influenza vaccine (UIV) that can elicit both broad and durable protection is of the utmost importance.
    Area covered: This review summarizes and compares the available influenza vaccines in the market and inactivation methods used for manufacturing IIVs. Then, we discuss the latest progress of the UIV development in the IIV format and the challenges to address for moving these vaccine candidates to clinical trials and commercialization. The literature search was based on the Centers for Disease Control and Prevention (CDC) and the PubMed databases.
    Expert opinion: The unmet need for UIV is the primary aim of developing the next generation of influenza vaccines. The IIV has high antigenicity and a refined manufacturing process compared to most other formats. Developing the UIV in IIV format is a promising direction with advanced biomolecular technologies and next-generation adjuvant. It also inspires the development of universal vaccines for other infectious diseases.
    MeSH term(s) Humans ; Influenza Vaccines ; Influenza, Human ; Vaccines, Inactivated ; Vaccination ; Seasons ; Antibodies, Viral
    Chemical Substances Influenza Vaccines ; Vaccines, Inactivated ; Antibodies, Viral
    Language English
    Publishing date 2024-03-25
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2181284-6
    ISSN 1744-8395 ; 1476-0584
    ISSN (online) 1744-8395
    ISSN 1476-0584
    DOI 10.1080/14760584.2024.2333338
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Book ; Online ; E-Book: Oxygen transport to Tissue XXXVIII

    Luo, Qingming / Li, Lin Z. / Harrison, David K. / Shi, Hua / Bruley, Duane F.

    (Advances in experimental medicine and biology ; 923)

    2016  

    Author's details Qingming Luo, Lin Z. Li, David K. Harrison, Hua Shi, Duane F. Bruley editors
    Series title Advances in experimental medicine and biology ; 923
    Collection
    Keywords Medicine ; Human physiology ; Immunology ; Respiratory organs/Diseases
    Subject code 612
    Language English
    Size 1 Online-Ressource (XXXIX, 453 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019129890
    ISBN 978-3-319-38810-6 ; 9783319388083 ; 3-319-38810-X ; 3319388088
    DOI 10.1007/978-3-319-38810-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book: Oxygen transport to Tissue XXXVIII

    Luo, Qingming / Li, Lin Z. / Harrison, David K. / Shi, Hua / Bruley, Duane F.

    (Advances in experimental medicine and biology ; 923)

    2016  

    Author's details Qingming Luo, Lin Li, David K. Harrison, Hua Shi, Duane F. Bruley editors
    Series title Advances in experimental medicine and biology ; 923
    Collection
    Keywords Hypoxia ; ISOTT ; Oxygenation ; cerebral blood flow ; oxygen supply ; tissue oximeter
    Language English
    Size XXX, 320 Seiten, Illustrationen, Diagramme, 23.5 cm x 15.5 cm, 0 g
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT019111887
    ISBN 978-3-319-38808-3 ; 3-319-38808-8 ; 9783319388106 ; 331938810X
    Database Catalogue ZB MED Medicine, Health

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    Zs A 3192 -923- not available for loan Zeitschriften-Lesesaal

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  5. Article ; Online: Esophageal tuberculosis.

    Hu, Qian / Zheng, Shi-Hua / Liu, Wei

    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology

    2024  

    Language English
    Publishing date 2024-03-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 632595-6
    ISSN 0975-0711 ; 0254-8860
    ISSN (online) 0975-0711
    ISSN 0254-8860
    DOI 10.1007/s12664-024-01533-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Tuberculous peritonitis.

    Hu, Qian / Zheng, Shi-Hua / Liu, Wei

    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology

    2024  

    Language English
    Publishing date 2024-01-15
    Publishing country India
    Document type Journal Article
    ZDB-ID 632595-6
    ISSN 0975-0711 ; 0254-8860
    ISSN (online) 0975-0711
    ISSN 0254-8860
    DOI 10.1007/s12664-023-01517-7
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  7. Article: Utility of cardiac magnetic resonance in the diagnosis of suspected "MINOCA": a case series and literature review.

    Yang, Kai / Zhao, Shi-Hua

    Radiology case reports

    2022  Volume 17, Issue 9, Page(s) 3399–3404

    Abstract: Myocardial infarction with nonobstructive coronary artery (MINOCA) is a common condition in clinical practice with multiple specific causes, such as plaque rupture, plaque erosion, and epicardial coronary vasospasm. There must be an ischemic mechanism ... ...

    Abstract Myocardial infarction with nonobstructive coronary artery (MINOCA) is a common condition in clinical practice with multiple specific causes, such as plaque rupture, plaque erosion, and epicardial coronary vasospasm. There must be an ischemic mechanism responsible for the myocyte injury and an exclusion of nonischemic mechanisms that can mimic myocardial infarction, and then a diagnosis of MINOCA can be made. Cardiac magnetic resonance (CMR) plays an essential role in the diagnosis and differential diagnosis of MINOCA, which cannot only exclude myocarditis, Takotsubo syndrome, and cardiomyopathies, but also provide imaging confirmation of acute myocardial infarction. In this study, we presented 2 typical cases with the clinical presentation of acute myocardial infarction but normal or nonobstructive epicardial coronary arteries. Further CMR examinations showed different patterns of late gadolinium enhancement (LGE) in these 2 cases, one case with subendocardial LGE of the anterolateral wall and the other one with subepicardial LGE of the lateral wall, which indicated 2 different mechanisms for the myocyte injury. Subsequently, these 2 patients received different treatment regimens and were discharged with improved symptoms. In conclusion, CMR should be a mandatory test in patients with suspected MINOCA, because it can not only make a clear diagnosis, but also play an important role in guiding clinical decision-making.
    Language English
    Publishing date 2022-07-21
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2022.06.101
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  8. Article ; Online: A two-year follow-up study on the first manic episode due to mood-incongruent psychosis.

    Shi, Hua-Meng / Jiang, De-Guo

    Asian journal of psychiatry

    2022  Volume 73, Page(s) 103118

    Abstract: Background: Mood-incongruent psychosis during bipolar disorder has been associated with poor outcomes. However, it remains unknown whether this is secondary to persistent affective or psychotic symptoms or both.: Method: Sixty-eight patients with ... ...

    Abstract Background: Mood-incongruent psychosis during bipolar disorder has been associated with poor outcomes. However, it remains unknown whether this is secondary to persistent affective or psychotic symptoms or both.
    Method: Sixty-eight patients with bipolar disorder between the ages of 16 and 45 were recruited during their first psychiatric hospitalization for mania. These patients were evaluated using structured and semi-structured clinical interview then followed longitudinally. Outcomes during the first twenty-four months of follow-up were compared between patients with mood-incongruent psychosis and those without (i.e., patients with mood-congruent psychosis or no psychosis) during the index manic episode. Specifically, ratings of the percent of weeks during follow-up with the duration of mood incongruent psychotic symptom, any psychotic symptom, affective syndromes, and scores of global outcomes were compared.
    Results: Comparing the 24-month follow-up results between the two groups, patients with mood incongruent psychotic symptoms had a lower global functional rating scale, efficacy index, while the duration of mood incongruent psychotic symptom, any psychotic symptom, and complete affective symptom showed statistically significant differences between the two groups. There were also statistically significant differences between the two groups in the duration of mood stabilizers, and antidepressants use, typical antipsychotics, and atypical antipsychotics. Partial correlation analysis reveals the scores of the global assessment of functioning scale (GAF) after 24 months showed a significant negative correlation with the length of time of incongruent psychotic symptoms. Still, the correlation was intermediate (correlation coefficients less than 0.5，r
    Conclusion: Mood-incongruent psychosis that occurs during the first manic episode appears to predict an increased likelihood of persistent psychotic symptoms during the subsequent twenty-four months. This persistence of psychosis is associated with a worse overall course of illness than patients without mood-incongruent psychosis.
    Limitations: These results apply to a relatively short outcome period, and the sample size is relatively small.
    MeSH term(s) Adolescent ; Adult ; Antipsychotic Agents/therapeutic use ; Bipolar Disorder/complications ; Bipolar Disorder/diagnosis ; Bipolar Disorder/drug therapy ; Follow-Up Studies ; Humans ; Mania ; Middle Aged ; Psychotic Disorders/complications ; Psychotic Disorders/etiology ; Young Adult
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 2022-04-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2022.103118
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  9. Article ; Online: Unified Strategy Enables the Collective Syntheses of Structurally Diverse Indole Alkaloids.

    Ren, Jian / Ding, Shi-Hua / Li, Xiao-Nian / Zhao, Qin-Shi

    Journal of the American Chemical Society

    2024  Volume 146, Issue 11, Page(s) 7616–7627

    Abstract: Natural products and their analogues are significant sources of therapeutic lead compounds. However, synthetic strategies for generating large collections of these molecules remain a significant challenge. The most difficult step in their synthesis is ... ...

    Abstract Natural products and their analogues are significant sources of therapeutic lead compounds. However, synthetic strategies for generating large collections of these molecules remain a significant challenge. The most difficult step in their synthesis is the design of a common intermediate that can be easily transformed into natural products belonging to different families. This study demonstrates the evolution of synthetic tactics designed to assemble the functionalized piperidines present in indole alkaloids from a common intermediate. More importantly, we also report a previously unknown Ir- and Er-catalyzed dehydrogenative spirocyclization reaction that enables direct access to spirocyclic oxindole alkaloids. As a practical application, the asymmetric total syntheses of 29 natural alkaloids belonging to different families were accomplished by following a uniform synthetic route. The proposed methodology extends the capability of the iridium-catalyzed dehydrogenative coupling reaction to the realm of indole-alkaloid synthesis and provides new opportunities for the efficient preparation of natural product-like molecules.
    MeSH term(s) Humans ; Stereoisomerism ; Indole Alkaloids ; Alkaloids ; Oxindoles ; Biological Products
    Chemical Substances Indole Alkaloids ; Alkaloids ; Oxindoles ; Biological Products
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.3c13869
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Flu-COVID combo recombinant protein vaccines elicited protective immune responses against both influenza and SARS-CoV-2 viruses infection.

    Huang, Ying / Shi, Hua / Forgacs, David / Ross, Ted M

    Vaccine

    2024  Volume 42, Issue 5, Page(s) 1184–1192

    Abstract: SARS-CoV-2 and Influenza viruses are both highly transmissible airborne viruses and causing high morbidity and mortality. Co-infection of these two viruses results in severe disease that have been observed when influenza and SARS-CoV-2 viruses ... ...

    Abstract SARS-CoV-2 and Influenza viruses are both highly transmissible airborne viruses and causing high morbidity and mortality. Co-infection of these two viruses results in severe disease that have been observed when influenza and SARS-CoV-2 viruses cocirculated in the past three years, and vaccination is still the effective way to prevent these two diseases. However, influenza and COVID-19 vaccines are designed and manufactured in different platforms, all the individuals will need to get two shots in order to prevent those two severe respiratory diseases. Therefore, it is urgent to develop a Flu-COVID combo vaccine to provide an efficient way for receiving immunization against those two diseases. In this study, we developed a flu-COVID combo vaccine that includes both influenza virus haemagglutinin (HA) proteins and SARS-CoV-2 Spike (S) protein which formulated with AddaVax. K18-hACE-2 transgenic mice were intramuscularly vaccinated with either combo vaccine or mono Flu (HA) or COVID (S) recombinant protein vaccine in a prime-boost-boost regimen, and then were challenged with lethal doses of influenza virus or SARS-CoV-2 to evaluate vaccine efficacy. The results showed that Flu-COVID combo vaccine protected mice from both Influenza and SARS-CoV-2 challenge by preventing body weight loss and clinical signs progression. The protective immune responses elicited by Flu-COVID combo vaccine were equivalent to those elicited by mono flu or COVID recombinant protein vaccines. In conclusion, our study highlights the effectiveness of the FLU-COVID combo recombinant protein vaccine in preventing both influenza and COVID-19 infections.
    MeSH term(s) Humans ; Mice ; Animals ; Influenza, Human/prevention & control ; SARS-CoV-2 ; Protein Subunit Vaccines ; COVID-19/prevention & control ; COVID-19 Vaccines ; Influenza Vaccines ; Orthomyxoviridae ; Vaccines, Synthetic/genetics ; Immunity ; Antibodies, Viral
    Chemical Substances Protein Subunit Vaccines ; COVID-19 Vaccines ; Influenza Vaccines ; Vaccines, Synthetic ; Antibodies, Viral
    Language English
    Publishing date 2024-01-30
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2023.12.084
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