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Article ; Online: Assessment of pre-extubating recurrent laryngeal nerve palsy using ultrasound in postoperative patients with esophageal cancer: a prospective observational study.

Kaneko, Tomomi / Kato, Takao / Shiko, Yuki / Kawasaki, Yohei / Koyama, Kaoru

2024 Volume 38, Issue 3, Page(s) 347–353

Abstract: Purpose: Ultrasound performed after extubation has been suggested to be useful for the diagnosis of recurrent laryngeal nerve (RLN) paralysis. However, the use of ultrasound for this purpose before extubation has not been examined. The aim of this study ...

Abstract	Purpose: Ultrasound performed after extubation has been suggested to be useful for the diagnosis of recurrent laryngeal nerve (RLN) paralysis. However, the use of ultrasound for this purpose before extubation has not been examined. The aim of this study was to examine the versatility (interrater reliability) and usefulness of ultrasound for evaluating the movement of vocal cords before extubation. Methods: The subjects were 30 patients who underwent radical surgery for esophageal cancer from August 2020 to December 2021. An experienced examiner performed an ultrasound examination before and after elective extubation on the day after surgery to evaluate RLN paralysis and record videos. Bronchoscopy was then performed to make a definite diagnosis. Three anesthetists blinded to the diagnosis also evaluated the cases using the videos, and the versatility of the examination was determined using a kappa test. Results: The diagnostic accuracies of the examiner and three anesthetists were 76.7%, 50.0%, 53.3%, and 46.7%, respectively, and the kappa coefficients for the examiner with the anesthetists were 0.310, 0.502, and 0.169, respectively. The sensitivity, specificity, positive predictive value and negative predictive value for diagnosis of RLN paralysis by the examiner using ultrasound before extubation were 0.57, 0.95, 0.80, and 0.87, respectively. Conclusion: These results indicate a lack of versatility of the ultrasound examination based on the low kappa coefficients. However, with an experienced examiner, ultrasound can serve as a non-invasive examination that can be performed before extubation with high accuracy and specificity for diagnosis of postoperative RLN paralysis.
MeSH term(s)	Humans ; Prospective Studies ; Male ; Female ; Esophageal Neoplasms/surgery ; Vocal Cord Paralysis/diagnostic imaging ; Vocal Cord Paralysis/etiology ; Aged ; Middle Aged ; Ultrasonography/methods ; Airway Extubation/methods ; Reproducibility of Results ; Postoperative Complications/diagnostic imaging ; Postoperative Complications/diagnosis ; Recurrent Laryngeal Nerve/diagnostic imaging ; Sensitivity and Specificity
Language	English
Publishing date	2024-03-02
Publishing country	Japan
Document type	Journal Article ; Observational Study
ZDB-ID	1107821-2
ISSN	1438-8359 ; 0913-8668
ISSN (online)	1438-8359
ISSN	0913-8668
DOI	10.1007/s00540-024-03315-7
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Article ; Online: Urine collection using a 3-way urethral catheter for PuO

Kato, Takao / Shiko, Yuki / Koyama, Kaoru

Journal of anesthesia

2023 Volume 38, Issue 2, Page(s) 284–285

MeSH term(s)	Urine Specimen Collection ; Urinary Catheters ; Oxygen
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2023-10-31
Publishing country	Japan
Document type	Letter
ZDB-ID	1107821-2
ISSN	1438-8359 ; 0913-8668
ISSN (online)	1438-8359
ISSN	0913-8668
DOI	10.1007/s00540-023-03276-3
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Article ; Online: Thumb Pronation Angle in Thumb Opposition Evaluated by the Nail Tip Angle of Thumb-Ring Finger Opposition.

Taniguchi, Shinji / Matsuura, Yusuke / Takehara, Tatsuya / Yamada, Ayae / Shiko, Yuki / Nakagawa, Koichi / Ohtori, Seiji

Hand (New York, N.Y.)

2024 , Page(s) 15589447241236249

Abstract: Background: This study aimed to devise the method for the evaluation of the thumb pronation angle and calculate its reference value.: Methods: The study was conducted from October 2021 to March 2022, and 600 hands of 300 healthy volunteers were ... ...

Abstract	Background: This study aimed to devise the method for the evaluation of the thumb pronation angle and calculate its reference value. Methods: The study was conducted from October 2021 to March 2022, and 600 hands of 300 healthy volunteers were included in this study. The participants were divided into 6 age groups with 50 participants each. In study 1, 12 participants from group 1 were randomly selected, which included 6 male and 6 female participants. We measured the thumb pronation angle using FASTRAK system and the nail tip angle of thumb-ring finger opposition (T-R angle) and also evaluated the relation between them. In study 2, we measured the T-R angle of 600 hands of 300 healthy volunteers. The T-R angle mean (SD) and 95% confidence interval (CI) of each age group were calculated as reference values. Results: The thumb pronation angle was correlated with the T-R angle. The T-R angle mean (SD) and 95% CI of the 6 groups were as follows: group 1, 142.5° (12.4) and 117.7 to 167.3; group 2, 139.9° (10.1) and 119.7 to 160.1; group 3, 142.3° (9.7) and 122.9 to 160.5; group 4, 140.2° (12.6) and 115.0 to 165.4; group 5, 138.3° (11.9) and 114.5 to 162.1; and group 6, 135.4° (13.0) and 109.4 to 161.4. The 95% CI tended to decrease with an increasing age. Conclusions: The T-R angle was a suitable evaluation method for the thumb pronation angle, and it should be evaluated by age groups.
Language	English
Publishing date	2024-03-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	2277325-3
ISSN	1558-9455 ; 1558-9447
ISSN (online)	1558-9455
ISSN	1558-9447
DOI	10.1177/15589447241236249
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Article ; Online: Progression of fluid infiltration on non-contrast magnetic resonance imaging in breast cancer-related lymphedema: A comparative analysis with indocyanine green lymphography.

Kageyama, Takashi / Shiko, Yuki / Kawasaki, Yohei / Miyazaki, Toko / Sakai, Hayahito / Tsukuura, Reiko / Yamamoto, Takumi

Journal of plastic, reconstructive & aesthetic surgery : JPRAS

2024 Volume 92, Page(s) 225–236

Abstract: Background: Non-contrast magnetic resonance imaging (NMRI) has been reported as valuable for the assessment of lymphedema. However, the correlation between NMRI findings and indocyanine green lymphography (ICG-L) findings remains elusive.: Methods: ... ...

Abstract	Background: Non-contrast magnetic resonance imaging (NMRI) has been reported as valuable for the assessment of lymphedema. However, the correlation between NMRI findings and indocyanine green lymphography (ICG-L) findings remains elusive. Methods: This single-center retrospective study included 26 patients diagnosed with breast cancer-related lymphedema. We examined the prevalence of fluid infiltration in eight regions of the upper extremity, the type of fluid distribution, and the dominant segment of edema on NMRI in comparison to the ICG-L stage. Statistical analysis was performed using the Cochran-Armitage trend test, Spearman's rank correlation test, and Fisher's exact test. Results: The regional fluid infiltration significantly increased with the progression of the ICG-L stage (hand, forearm, elbow, and upper arm: p = 0.003, <0.001, <0.001, and <0.001, respectively). The fluid distribution significantly advanced with the progression of the ICG-L stage as follows (r Conclusions: Fluid infiltration observed on NMRI exhibited distinct patterns with the progression of the ICG-L stage. We believe that anatomical information regarding fluid distribution would potentially contribute to optimizing surgical efficacy.
Language	English
Publishing date	2024-03-24
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2217750-4
ISSN	1878-0539 ; 1748-6815 ; 0007-1226
ISSN (online)	1878-0539
ISSN	1748-6815 ; 0007-1226
DOI	10.1016/j.bjps.2024.03.016
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Article ; Online: Protocolized oxytocin infusion for elective cesarean delivery: a retrospective before-and-after study.

Nagai, Azusa / Shiko, Yuki / Noguchi, Shohei / Ikeda, Yusuke / Kawasaki, Yohei / Mazda, Yusuke

Journal of anesthesia

2024

Abstract: Purpose: To elucidate the clinical impact of the novel oxytocin protocol using a syringe pump with a stratified dose compared with the conventional practice of putting oxytocin into the bag.: Methods: This is a retrospective cohort study. We ... ...

Abstract	Purpose: To elucidate the clinical impact of the novel oxytocin protocol using a syringe pump with a stratified dose compared with the conventional practice of putting oxytocin into the bag. Methods: This is a retrospective cohort study. We collected the data of the patients who underwent elective cesarean delivery under neuraxial anesthesia between June 2019 and May 2020. The patients were allocated to two groups according to oxytocin administration methods; the control group (the attending anesthesiologist put oxytocin 5-10 units in the infusion bag and adjusted manually after childbirth) and the protocol group (the oxytocin protocol gave oxytocin bolus 1 or 3 units depending on the PPH risk, followed by 5 or 10 unit h Results: During the study period, 262 parturients were included. Oxytocin doses of intraoperative and postoperative were significantly lower in the protocol group (9.7 vs. 11.7 units, intraoperative, 15.9 vs. 18 units, postoperative). The subgroup analyses showed that the impact was more remarkable in the low PPH risk than in the high PPH risk. The multivariate linear regression analyses also confirmed the difference. The groups had no significant difference in blood loss, requirement of additional uterotonics, and other adverse events. Conclusions: Our oxytocin infusion protocol significantly reduced oxytocin requirements in elective cesarean delivery under neuraxial anesthesia without increasing blood loss. However, we could not find other clinical benefits of the novel protocol.
Language	English
Publishing date	2024-03-22
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1107821-2
ISSN	1438-8359 ; 0913-8668
ISSN (online)	1438-8359
ISSN	0913-8668
DOI	10.1007/s00540-024-03329-1
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Article ; Online: Three-dimensional non-contrast magnetic resonance lymphography severity stage for upper extremity lymphedema.

Kageyama, Takashi / Shiko, Yuki / Kawasaki, Yohei / Miyazaki, Toko / Sakai, Hayahito / Tsukuura, Reiko / Yamamoto, Takumi

Magnetic resonance imaging

2024 Volume 107, Page(s) 24–32

Abstract: Purposes: Non-contrast magnetic resonance lymphography (NMRL) has recently shown the capability of evaluating anatomical fluid distribution in upper extremity lymphedema (UEL). However, there is still a lack of knowledge about the correlation between ... ...

Abstract	Purposes: Non-contrast magnetic resonance lymphography (NMRL) has recently shown the capability of evaluating anatomical fluid distribution in upper extremity lymphedema (UEL). However, there is still a lack of knowledge about the correlation between the characteristic three-dimensional (3D) NMRL findings and the indocyanine green lymphography (ICG-L) findings. Our goal was to clarify the relationship between the 3D NMRL findings and the ICG-L findings. Methods: Medical charts of patients with secondary UEL who underwent NMRL and ICG-L between January 2018 to October 2021 were reviewed. The upper extremities were divided into 6 regions; the hand, elbow, and the radial and ulnar aspects of the forearm and the upper arm. We investigated the prevalence of characteristic 3D NMRL patterns (Mist/Spray/Inky) in each region based on the ICG-L stage. We also examined the association between the 3D NMRL stage which we proposed and the ICG-L stage, and other clinical factors. Results: A total of 150 regions of 25 patients with upper extremities lymphedema were enrolled in the study. All of the characteristic patterns increased significantly as the ICG-L stage advanced (p < 0.001, < 0.001, and < 0.001, respectively). The predominant NMRL patterns changed significantly from the Early pattern (Mist pattern) to the Advanced pattern (Inky/Spray pattern) as the ICG-L stage progressed (p < 0.001). The higher Stage of 3D NMRL was significantly associated with the progression of the ICG-L stage (r Conclusions: Characteristic 3D NMRL patterns and the 3D NMRL Stage had a significant relationship with the ICG-L stage and other clinical parameters. This information may be an efficient tool for a more precise and objective evaluation of various treatments for UEL patients.
MeSH term(s)	Humans ; Lymphography/methods ; Retrospective Studies ; Indocyanine Green ; Lymphedema/diagnostic imaging ; Upper Extremity/diagnostic imaging ; Magnetic Resonance Spectroscopy
Chemical Substances	Indocyanine Green (IX6J1063HV)
Language	English
Publishing date	2024-01-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	604885-7
ISSN	1873-5894 ; 0730-725X
ISSN (online)	1873-5894
ISSN	0730-725X
DOI	10.1016/j.mri.2023.12.007
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Article ; Online: A Descriptive Study of the Characteristics of Homicide-Suicide in Forensic Autopsy Cases.

Oya, Yukiko / Ishihara, Kenji / Shiko, Yuki / Kawasaki, Yohei / Iwase, Hirotaro

Journal of interpersonal violence

2023 Volume 39, Issue 7-8, Page(s) 1473–1495

Abstract: Homicide followed by suicide (HS) is a tragic event with varied characteristics across countries and regions. Compared to Western countries, there are limited studies on HS in Asian countries. Therefore, this study aimed to clarify the characteristics of ...

Abstract	Homicide followed by suicide (HS) is a tragic event with varied characteristics across countries and regions. Compared to Western countries, there are limited studies on HS in Asian countries. Therefore, this study aimed to clarify the characteristics of recent HS cases by examining forensic autopsy records from 2008 to 2020 collected from the Department of Legal Medicine, Chiba University, in Japan. A total of 77 HS cases were identified, involving 77 perpetrators (52 completed suicides, 25 attempted suicides), with 28 perpetrator and 89 victim autopsies. Our findings showed that older adults accounted for nearly half of the victims; victims were mostly females, whereas most perpetrators were male. The most common HS relationship was that between a parent and a child. Autopsy findings showed that the most common cause of death was strangulation, and illegal drugs were detected only in a few cases; however, psychotropic drugs were detected in child victims. No obvious evidence of past child physical abuse by caregivers was found. In contrast, intimate partner violence (IPV) was present, with a history of IPV found in half of HS cases involving adult intimate partner relationships. Notably, gender differences in age and relationship to the victim were identified. Likewise, some perpetrators may have expressed their plans and intentions for HS before the event, which may represent an important sign for HS prevention. However, to accurately reveal the course of HS, nationwide integrated statistics, forensic autopsies, including toxicological analyses of the deceased; and forensic psychiatric perspectives, including psychological autopsy, are required.
MeSH term(s)	Child ; Female ; Humans ; Male ; Aged ; Homicide ; Autopsy ; Child Abuse ; Forensic Medicine ; Suicide, Attempted
Language	English
Publishing date	2023-10-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2028900-5
ISSN	1552-6518 ; 0886-2605
ISSN (online)	1552-6518
ISSN	0886-2605
DOI	10.1177/08862605231207616
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Article: Relationship Between Clinical Symptoms and Skin Autofluorescence in Hemodialysis Patients as a Measure of Advanced Glycation End-Product Accumulation.

Suzuki, Masahiro / Hanaoka, Eiji / Shiko, Yuki / Kawasaki, Yohei / Ohtori, Seiji

Cureus

2022 Volume 14, Issue 7, Page(s) e27081

Abstract: Background The purpose of this study was to investigate the relationship between skin autofluorescence (SAF), as a measure of advanced glycation end-product (AGE) accumulation and osteoporosis and clinical symptoms in hemodialysis patients. Methodology ... ...

Abstract	Background The purpose of this study was to investigate the relationship between skin autofluorescence (SAF), as a measure of advanced glycation end-product (AGE) accumulation and osteoporosis and clinical symptoms in hemodialysis patients. Methodology The study participants were 156 hemodialysis patients (97 males, 59 females, mean = 66.9 years, range = 25-92 years) who visited our hospital between October 2019 and March 2020. The average dialysis period was 10.4 years (range = 1-40 years). Age, years of dialysis, bone mineral density, bone metabolism markers (Ca, P, intact parathyroid hormone, total N-terminal propeptide of type 1 collagen, tartrate-resistant acid phosphatase-5b), clinical symptoms, and SAF were evaluated. Clinical symptoms were evaluated using the visual analog scale (VAS) score for low back pain (LBP) and leg pain ranging from 10 mm (extreme amount of pain) to 0 mm (no pain); the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire (JOABPEQ; 0-100 points); and the Roland-Morris Disability Questionnaire (RDQ; 0-24 points). We calculated Pearson correlation coefficients to assess the correlation of SAF with age, years of hemodialysis, bone density, bone metabolism markers, clinical symptoms, and biochemical markers. Results The SAF of dialysis patients averaged 4.11, higher than previous reports for non-dialysis patients. Age (r = 0.435, p = 0.0001) was moderately positively correlated and hemodialysis period (r = 0.214, p = 0.00907) was weakly positively correlated with SAF. Among the clinical symptoms measured by the JOABPEQ, social life dysfunction (r = -0.257, p = 0.0108) had a weak negative correlation with SAF. Conclusions The level of AGEs implied by SAF was elevated in hemodialysis patients. SAF correlated with social life disorders, suggesting that SAF may be involved in disorders of activities of daily living in hemodialysis dialysis patients.
Language	English
Publishing date	2022-07-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.27081
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Article ; Online: Are serum oxytocin concentrations lower in patients with treatment-resistant schizophrenia?: A 5-year longitudinal study.

Kanahara, Nobuhisa / Nakamura, Miwako / Shiko, Yuki / Kawasaki, Yohei / Iyo, Masaomi

Asian journal of psychiatry

2022 Volume 76, Page(s) 103157

MeSH term(s)	Antipsychotic Agents/therapeutic use ; Clozapine/therapeutic use ; Humans ; Longitudinal Studies ; Oxytocin/therapeutic use ; Schizophrenia/drug therapy ; Schizophrenia, Treatment-Resistant
Chemical Substances	Antipsychotic Agents ; Oxytocin (50-56-6) ; Clozapine (J60AR2IKIC)
Language	English
Publishing date	2022-05-06
Publishing country	Netherlands
Document type	Letter
ZDB-ID	2456678-0
ISSN	1876-2026 ; 1876-2018
ISSN (online)	1876-2026
ISSN	1876-2018
DOI	10.1016/j.ajp.2022.103157
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Article ; Online: A Double-Blind, Randomized, Placebo-Controlled Trial of the Effect of 1-Kestose on Defecation Habits in Constipated Kindergarten Children: A Pilot Study.

Takahashi, Mayuko / Kadota, Yoshihiro / Shiko, Yuki / Kawasaki, Yohei / Sakurai, Kenichi / Mori, Chisato / Shimojo, Naoki

Nutrients

2023 Volume 15, Issue 14

Abstract: Constipation is common in children and can significantly affect quality of life. Prebiotics are reportedly helpful for constipation in adults, but few studies have examined their use in young children. In this study, the effect of 1-kestose (kestose), ... ...

Abstract	Constipation is common in children and can significantly affect quality of life. Prebiotics are reportedly helpful for constipation in adults, but few studies have examined their use in young children. In this study, the effect of 1-kestose (kestose), which has excellent bifidobacterial growth properties, on constipation in kindergarten children (
MeSH term(s)	Adult ; Humans ; Child ; Child, Preschool ; Defecation ; Pilot Projects ; Double-Blind Method ; Quality of Life ; Constipation/drug therapy ; Constipation/microbiology ; Feces/microbiology ; Treatment Outcome
Chemical Substances	1-kestose (02LN7O412C)
Language	English
Publishing date	2023-07-24
Publishing country	Switzerland
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15143276
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