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Article: Reduction in urban atmospheric CO

Park, Chaerin / Jeong, Sujong / Shin, Yong-Seung / Cha, Yeong-Seop / Lee, Ho-Chan

2021 Volume 12, Issue 9, Page(s) 101176

Abstract: With the spread of the COVID-19 virus globally, cities worldwide have implemented unprecedented social distancing policies to mitigate infection rates. Many studies have demonstrated that improved air quality and reduced carbon emissions have resulted ... ...

Abstract	With the spread of the COVID-19 virus globally, cities worldwide have implemented unprecedented social distancing policies to mitigate infection rates. Many studies have demonstrated that improved air quality and reduced carbon emissions have resulted from the COVID-19 pandemic. Yet, questions remain regarding changes in atmospheric CO
Language	English
Publishing date	2021-08-21
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	2645757-X
ISSN	1309-1042
ISSN	1309-1042
DOI	10.1016/j.apr.2021.101176
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Policy Directions Addressing the Public Health Impact of Climate Change in South Korea: The Climate-change Health Adaptation and Mitigation Program.

Shin, Yong Seung / Ha, Jongsik

Environmental health and toxicology

2012 Volume 27, Page(s) e2012018

Abstract: Climate change, caused by global warming, is increasingly recognized as a major threat to mankind's survival. Climate change concurrently has both direct and modifying influences on environmental, social, and public health systems undermining human ... ...

Abstract	Climate change, caused by global warming, is increasingly recognized as a major threat to mankind's survival. Climate change concurrently has both direct and modifying influences on environmental, social, and public health systems undermining human health as a whole. Environmental health policy-makers need to make use of political and technological alternatives to address these ramifying effects. The objective of this paper is to review public health policy in Korea, as well as internationally, particularly as it relates to climate change health adaptation and mitigation programs (such as C-CHAMP of Korea), in order to assess and elicit directions for a robust environmental health policy that is adaptive to the health impacts of climate change. In Korea, comprehensive measures to prevent or mitigate overall health effects are limited, and the diffusion of responsibility among various government departments makes consistency in policy execution very difficult. This paper proposes integration, synergy, and utilization as the three core principles of policy direction for the assessment and adaptation to the health impacts of climate change. For specific action plans, we suggest policy making based on scientifically integrated health impact assessments and the prioritization of environmental factors in climate change; the development of practical and technological tools that support policy decisions by making their political implementation more efficient; and customized policy development that deals with the vulnerability of local communities.
Language	English
Publishing date	2012-11-30
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2639818-7
ISSN	2233-6567 ; 2233-6567
ISSN (online)	2233-6567
ISSN	2233-6567
DOI	10.5620/eht.2012.27.e2012018
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Brain lipidomics: From functional landscape to clinical significance.

Yoon, Jong Hyuk / Seo, Youngsuk / Jo, Yeon Suk / Lee, Seulah / Cho, Eunji / Cazenave-Gassiot, Amaury / Shin, Yong-Seung / Moon, Myeong Hee / An, Hyun Joo / Wenk, Markus R / Suh, Pann-Ghill

Science advances

2022 Volume 8, Issue 37, Page(s) eadc9317

Abstract: Lipids are crucial components of cellular function owing to their role in membrane formation, intercellular signaling, energy storage, and homeostasis maintenance. In the brain, lipid dysregulations have been associated with the etiology and progression ... ...

Abstract	Lipids are crucial components of cellular function owing to their role in membrane formation, intercellular signaling, energy storage, and homeostasis maintenance. In the brain, lipid dysregulations have been associated with the etiology and progression of neurodegeneration and other neurological pathologies. Hence, brain lipids are emerging as important potential targets for the early diagnosis and prognosis of neurological diseases. This review aims to highlight the significance and usefulness of lipidomics in diagnosing and treating brain diseases. We explored lipid alterations associated with brain diseases, paying attention to organ-specific characteristics and the functions of brain lipids. As the recent advances in brain lipidomics would have been impossible without advances in analytical techniques, we provide up-to-date information on mass spectrometric approaches and integrative analysis with other omic approaches. Last, we present the potential applications of lipidomics combined with artificial intelligence techniques and interdisciplinary collaborative research for treating brain diseases with clinical heterogeneities.
MeSH term(s)	Artificial Intelligence ; Brain ; Brain Diseases/diagnosis ; Brain Diseases/etiology ; Humans ; Lipid Metabolism ; Lipidomics ; Lipids/chemistry
Chemical Substances	Lipids
Language	English
Publishing date	2022-09-16
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2810933-8
ISSN	2375-2548 ; 2375-2548
ISSN (online)	2375-2548
ISSN	2375-2548
DOI	10.1126/sciadv.adc9317
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Development of real-time dual-display handheld and bench-top hybrid-mode SD-OCTs.

Cho, Nam Hyun / Park, Kibeom / Wijesinghe, Ruchire Eranga / Shin, Yong Seung / Jung, Woonggyu / Kim, Jeehyun

Sensors (Basel, Switzerland)

2014 Volume 14, Issue 2, Page(s) 2171–2181

Abstract: Development of a dual-display handheld optical coherence tomography (OCT) system for retina and optic-nerve-head diagnosis beyond the volunteer motion constraints is reported. The developed system is portable and easily movable, containing the compact ... ...

Abstract	Development of a dual-display handheld optical coherence tomography (OCT) system for retina and optic-nerve-head diagnosis beyond the volunteer motion constraints is reported. The developed system is portable and easily movable, containing the compact portable OCT system that includes the handheld probe and computer. Eye posterior chambers were diagnosed using the handheld probe, and the probe could be fixed to the bench-top cradle depending on the volunteers' physical condition. The images obtained using this handheld probe were displayed in real time on the computer monitor and on a small secondary built-in monitor; the displayed images were saved using the handheld probe's built-in button. Large-scale signal-processing procedures such as k-domain linearization, fast Fourier transform (FFT), and log-scaling signal processing can be rapidly applied using graphics-processing-unit (GPU) accelerated processing rather than central-processing-unit (CPU) processing. The Labview-based system resolution is 1,024 × 512 pixels, and the frame rate is 56 frames/s, useful for real-time display. The 3D images of the posterior chambers including the retina, optic-nerve head, blood vessels, and optic nerve were composed using real-time displayed images with 500 × 500 × 500 pixel resolution. A handheld and bench-top hybrid mode with a dual-display handheld OCT was developed to overcome the drawbacks of the conventional method.
Language	English
Publishing date	2014-01-27
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s140202171
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Atmospheric pressure-thermal desorption (AP-TD)/electrospray ionization-mass spectrometry for the rapid analysis of Bacillus spores.

Basile, Franco / Zhang, Shaofeng / Shin, Yong-Seung / Drolet, Barbara

The Analyst

2010 Volume 135, Issue 4, Page(s) 797–803

Abstract: A technique is described where an atmospheric pressure-thermal desorption (AP-TD) device and electrospray ionization (ESI)-mass spectrometry (MS) are coupled and used for the rapid analysis of Bacillus subtilis spores in complex matrices. The resulting ... ...

Abstract	A technique is described where an atmospheric pressure-thermal desorption (AP-TD) device and electrospray ionization (ESI)-mass spectrometry (MS) are coupled and used for the rapid analysis of Bacillus subtilis spores in complex matrices. The resulting AP-TD/ESI-MS technique combines the generation of volatile compounds and/or pyrolysis products with soft-ionization MS detection. In the AP-TD/ESI-MS approach, an electrospray solvent plume was used as the ionization vehicle of thermally desorbed neutrals at atmospheric pressure prior to mass spectrometric analysis using a quadrupole ion trap mass spectrometer. The approach is quantitative with the volatile standard dimethyl methylphosphonate (DMMP) and with the use of an internal standard (diethyl methylphosphonate, DEMP). A linear response was obtained as tested in the 1-50 ppm range (R(2) = 0.991) with a standard error of the estimate of 0.193 (0.9% RSD, n = 5). Bacterial spores were detected by performing pyrolysis in situ methylation with the reagent tetramethylammonium hydroxide (TMAH) for the detection of the bacterial spore biomarker dipicolinic acid (DPA) as the dimethylated derivative (2Me-DPA). This approach allowed spore detection even in the presence of growth media in crude lyophilized samples. Repetitive analyses could be performed with a duty cycle of less than 5 min total analysis time (including sample loading, heating and data acquisition). This strategy proved successful over other direct ambient MS approaches like DESI-MS and AP-TD/ESI-MS without the in situ derivatization step to detect the dipicolinic acid biomarker from spores. A detection limit for the dimethylated DPA biomarker was estimated at 1 ppm (equivalent to 0.01 mug of DPA deposited in the thermal desorption tube), which corresponded to a calculated detection limit of 10(5) spores deposited or 0.1% by weight spore composition in solid samples (assuming a 1 mg sample size). The AP-TD/ESI source used in conjunction with the in situ methylation step allowed the differentiation of bacterial spores from other 'suspicious white powders' using a single stage for mass analysis and with minimum sample preparation, making this approach suitable for simple field-portable MS instrumentation and pattern recognition data analysis.
MeSH term(s)	Atmospheric Pressure ; Bacillus/isolation & purification ; Picolinic Acids/chemistry ; Spectrometry, Mass, Electrospray Ionization/instrumentation ; Spectrometry, Mass, Electrospray Ionization/methods ; Spores, Bacterial/isolation & purification ; Temperature
Chemical Substances	Picolinic Acids ; dipicolinic acid (UE81S5CQ0G)
Language	English
Publishing date	2010-04
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	210747-8
ISSN	1364-5528 ; 0003-2654
ISSN (online)	1364-5528
ISSN	0003-2654
DOI	10.1039/c0an00071j
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: On-Probe Pyrolysis Desorption Electrospray Ionization (DESI) Mass Spectrometry for the Analysis of Non-Volatile Pyrolysis Products.

Zhang, Shaofeng / Shin, Yong-Seung / Mayer, Richard / Basile, Franco

Journal of analytical and applied pyrolysis

2009 Volume 80, Issue 2, Page(s) 353–359

Abstract: An on-probe pyrolyzer has been constructed and interfaced with Desorption Electrospray Ionization (DESI) Mass Spectrometry (MS) for the rapid analysis of non-volatile pyrolysis products. The detection and analysis of non-volatile pyrolysis products of ... ...

Abstract	An on-probe pyrolyzer has been constructed and interfaced with Desorption Electrospray Ionization (DESI) Mass Spectrometry (MS) for the rapid analysis of non-volatile pyrolysis products. The detection and analysis of non-volatile pyrolysis products of peptides, proteins and the synthetic polymer poly(ethylene glycol) are demonstrated with this instrument. The on-probe pyrolyzer can be operated off-line or on-line with the DESI source and was interfaced with a tandem MS (MS/MS) instrument, which allowed for structure characterization of the non-volatile pyrolytic products. Advantages of this system are its simplicity and speed of analysis since the pyrolysis is performed in situ on the DESI source probe and hence, it avoids extraction steps and/or the use of matrices (e.g., as in MALDI-MS analyses).
Language	English
Publishing date	2009-10-29
Publishing country	Netherlands
Document type	Journal Article
ISSN	0165-2370
ISSN	0165-2370
DOI	10.1016/j.jaap.2007.04.005
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book: Introduction to Consumer Exposure Modeling Technologies for Hazardous Substance - Containing Products in Korea

Shin, Yong Seung / Bae, Kyung Eun

2006 Volume RE-2006/15S, Page(s) 19 S., Anh.

Language	English
Document type	Book
ISBN	978-89-8464-240-9
Database	OPAC and Environmental database (ULIDAT) of The Federal Environment Agency (UBA)

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Article: Exploration of immunoblot profiles of Neospora caninum probed with different bovine immunoglobulin classes.

Shin, Yong-Seung / Lee, Eung-Goo / Jung, Tae-Sung

Journal of veterinary science

2005 Volume 6, Issue 2, Page(s) 157–160

Abstract: The present study was attempted to compare the Neospora caninum (N. caninum) antigenic bands recognized by different bovine immunoglobulin classes. A total 10, 5, 2, and 6 antigenic bands were exhibited on immunoblot profiles against bovine IgM, IgE, IgA, ...

Abstract	The present study was attempted to compare the Neospora caninum (N. caninum) antigenic bands recognized by different bovine immunoglobulin classes. A total 10, 5, 2, and 6 antigenic bands were exhibited on immunoblot profiles against bovine IgM, IgE, IgA, and IgG, respectively. A 46 kDa band was probed as a common antigenic band except IgA; 69 kDa band was bovine IgM and IgE; 33, 37, 55, and 79 kDa bands were bovine IgM and IgG; 72 kDa band was found IgM and IgA profiles. Based on the analysis, it appeared that different immunoglobulin classes recognizing different antigenic molecules were cooperating to cope with neosporosis.
MeSH term(s)	Animals ; Antigens, Protozoan/immunology ; Cattle ; Cattle Diseases/diagnosis ; Cattle Diseases/immunology ; Cattle Diseases/parasitology ; Coccidiosis/diagnosis ; Coccidiosis/immunology ; Coccidiosis/parasitology ; Coccidiosis/veterinary ; Female ; Immunoblotting ; Immunoglobulin Idiotypes/immunology ; Neospora/immunology
Chemical Substances	Antigens, Protozoan ; Immunoglobulin Idiotypes
Language	English
Publishing date	2005-06
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2125308-0
ISSN	1976-555X ; 1229-845X
ISSN (online)	1976-555X
ISSN	1229-845X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Interrelationship of Pyrogenic Polycyclic Aromatic Hydrocarbon (PAH) Contamination in Different Environmental Media.

Kim, Seung-Kyu / Lee, Dong Soo / Shim, Won Joon / Yim, Un Hyuk / Shin, Yong-Seung

Sensors (Basel, Switzerland)

2009 Volume 9, Issue 12, Page(s) 9582–9602

Abstract: Interrelationships between pyrogenic polycyclic aromatic hydrocarbons (PAHs) were assessed in air, soil, water, sediment, and tree leaves by using multi-media monitoring data. Concurrent concentration measurements were taken bimonthly for a year for the ... ...

Abstract	Interrelationships between pyrogenic polycyclic aromatic hydrocarbons (PAHs) were assessed in air, soil, water, sediment, and tree leaves by using multi-media monitoring data. Concurrent concentration measurements were taken bimonthly for a year for the multi-media at urban and suburban sites. PAH level correlations between air and other media were observed at the urban site but were less clear at the suburban site. Considering a closer PAHs distribution/fate characteristics to soil than suspended solids, contamination in sediment seemed to be governed primarily by that in soil. The partitioning of PAHs in waters could be better accounted for by sorption onto black carbon and dissolved organic carbon.
Language	English
Publishing date	2009-11-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220
ISSN	1424-8220
DOI	10.3390/s91209582
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Desorption electrospray ionization mass spectrometry of intact bacteria

Meetani, Mohammed A / Shin, Yong-Seung / Zhang, Shaofeng / Mayer, Richard / Basile, Franco

Journal of mass spectrometry. 2007 Sept., v. 42, no. 9

2007

Abstract: Desorption electrospray ionization (DESI) mass spectrometry (MS) was used to differentiate seven bacteria species on the basis of their measured DESI-mass spectral profile. Both gram-positive and gram-negative bacteria were tested and included ... ...

Abstract	Desorption electrospray ionization (DESI) mass spectrometry (MS) was used to differentiate seven bacteria species on the basis of their measured DESI-mass spectral profile. Both gram-positive and gram-negative bacteria were tested and included Escherichia coli, Staphyloccocus aureus, Enterococcus sp., Bordetella bronchiseptica, Bacillus thuringiensis, Bacillus subtilis and Salmonella typhimurium. Distinct DESI-mass spectra, in the mass range of 50-500 u, were obtained from whole bacteria in either positive or negative ion modes in less than 2 mins analysis time. Positive ion DESI-mass spectral fingerprints were compared using principal components analysis (PCA) to investigate reproducibility for the intraday and the day-to-day measurements and the method selectivity to differentiate the bacteria studied. Detailed study of variances in the assay revealed that a large contribution to the DESI-mass spectral fingerprint variation was the growth media preparation procedure. Specifically, experiments conducted with the growth media prepared using the same batch yielded highly reproducible DESI-mass spectra, both in intraday and in day-to-day analyses (i.e. one batch of growth media used over a 3-day period versus a new batch every day over the same 3-day period). Conclusions are drawn from our findings in terms of strategies for rapid biodetection with DESI-MS.
Keywords	bacteria ; Gram-negative bacteria ; Gram-positive bacteria ; mass spectrometry ; principal component analysis
Language	English
Dates of publication	2007-09
Size	p. 1186-1193.
Publishing place	John Wiley & Sons, Ltd.
Document type	Article
ZDB-ID	1221763-3
ISSN	1096-9888 ; 1076-5174
ISSN (online)	1096-9888
ISSN	1076-5174
DOI	10.1002/jms.1250
Database	NAL-Catalogue (AGRICOLA)

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