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  1. Article: Integrative management of diabetic foot ulcers - A case series.

    Shindhe, Pradeep S / Kale, Ajay Pandurang / Killedar, Ramesh S

    Journal of Ayurveda and integrative medicine

    2023  Volume 14, Issue 5, Page(s) 100770

    Abstract: Diabetic foot ulcer (DFU) is a serious complication of diabetes mellitus and a cause of significant morbidity, mortality and healthcare expenditure. Treatment of DFU includes multimodal approach like surgical debridement, infection control, vascular ... ...

    Abstract Diabetic foot ulcer (DFU) is a serious complication of diabetes mellitus and a cause of significant morbidity, mortality and healthcare expenditure. Treatment of DFU includes multimodal approach like surgical debridement, infection control, vascular assessment, dressing etc. Multidisciplinary approach towards foot care is becoming a mainstay of therapy, and even with this comprehensive approach, there is still room for improvement in DFU outcomes. Integrative management includes the adoption of various systems of treatment with standard treatment for better outcomes. In the present case series, six cases of DFU were managed with the integration of Ayurveda and allopathic treatments. The cases were managed according to the standard diabetic foot ulcer management principles like surgical debridement, insulin therapy, along with incorporation of Ayurveda procedures like Vimlapana, Prakshalana, Bandhana etc. Standard assessment of ulcers at different time points was done using the Bates- Jensen Ulcer assessment tool. All the six DFU healed with minimal scar formation and in less time, lowering the risk of further amputation. Promising results were obtained in all six cases by adopting integrated Ayurveda and allopathic treatments, which indicates the potential benefits of alternative systems of medicine.
    Language English
    Publishing date 2023-09-06
    Publishing country United States
    Document type Case Reports
    ISSN 0975-9476
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2023.100770
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Protocol based pain management by Ayurveda parasurgical procedures W.S.R to musculoskeletal pain and its critical appraisal - An open labeled clinical trial.

    Mishra, Vibhuti / Shindhe, Pradeep S / Killedar, Ramesh S

    Journal of Ayurveda and integrative medicine

    2022  Volume 13, Issue 4, Page(s) 100665

    Abstract: Background: Pain has globally become an attention problem which causes discomfort by affecting the body as well as the mind. The International association of pain estimated that 1 in 5 patients experiences the pain, i.e. 30% of world population. 19.3% ( ... ...

    Abstract Background: Pain has globally become an attention problem which causes discomfort by affecting the body as well as the mind. The International association of pain estimated that 1 in 5 patients experiences the pain, i.e. 30% of world population. 19.3% (180-200 million) of the total population in India suffer from chronic pain and its severity appeals early approach of patients to hospitals. Ayurveda being the oldest medical science emphasized its importance and treatment of pain with both pharmacological and non-pharmacological (Parasurgical) methods.
    Objective: To evaluate the efficacy of non-pharmacological (para surgical) procedures in the management of pain.
    Materials and method: Total 100 patients with chronic musculoskeletal pain fulfilling the inclusion criteria were recruited by assessing the site, severity and nature of pain. A special protocol was framed by incorporating Ayurveda treatment principles by using Para surgical procedures such as Agnikarma (Therapeutic burn), Jalauka (leech therapy), Alabu (Cupping therapy) and Siravyadha (Vein puncture). The parameters like VAS and VDS pertaining to pain were assessed from baseline and at various time points. Statistical analysis was performed by using Wilcoxon match paired test to assess the results.
    Results: The VAS and VDS scale were used to assess the efficacy of para-surgical procedures which was found to be significant (p < 0.0001) from baseline and at various time points.
    Conclusion: Protocol based pain management by various para surgical procedures was found effective in the management of chronic musculoskeletal pain. The ambiguity in selection of proper parasurgical procedure for pain management is justified by following the protocol.
    Language English
    Publishing date 2022-11-24
    Publishing country United States
    Document type Journal Article
    ISSN 0975-9476
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2022.100665
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Integrative management of diabetic foot ulcers – A case series

    Shindhe, Pradeep S. / Kale, Ajay Pandurang / Killedar, Ramesh S.

    Journal of Ayurveda and Integrative Medicine. 2023 Sept., Oct., v. 14, no. 5 p.100770-

    2023  

    Abstract: Diabetic foot ulcer (DFU) is a serious complication of diabetes mellitus and a cause of significant morbidity, mortality and healthcare expenditure. Treatment of DFU includes multimodal approach like surgical debridement, infection control, vascular ... ...

    Abstract Diabetic foot ulcer (DFU) is a serious complication of diabetes mellitus and a cause of significant morbidity, mortality and healthcare expenditure. Treatment of DFU includes multimodal approach like surgical debridement, infection control, vascular assessment, dressing etc. Multidisciplinary approach towards foot care is becoming a mainstay of therapy, and even with this comprehensive approach, there is still room for improvement in DFU outcomes. Integrative management includes the adoption of various systems of treatment with standard treatment for better outcomes. In the present case series, six cases of DFU were managed with the integration of Ayurveda and allopathic treatments. The cases were managed according to the standard diabetic foot ulcer management principles like surgical debridement, insulin therapy, along with incorporation of Ayurveda procedures like Vimlapana, Prakshalana, Bandhana etc. Standard assessment of ulcers at different time points was done using the Bates- Jensen Ulcer assessment tool. All the six DFU healed with minimal scar formation and in less time, lowering the risk of further amputation. Promising results were obtained in all six cases by adopting integrated Ayurveda and allopathic treatments, which indicates the potential benefits of alternative systems of medicine.
    Keywords Ayurvedic medicine ; amputation ; debridement ; diabetic foot ; disease control ; health care costs ; insulin replacement therapy ; mortality ; risk ; Diabetic foot ulcer (DFU) ; Integrative management ; Bates- jensen ulcer assessment tool ; Vrana Ropana ; Vrana Shodhana
    Language English
    Dates of publication 2023-09
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Pre-press version ; Use and reproduction
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2023.100770
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Efficacy of Jatyadi, Madhughrita and honey tulle in wound management: a three-arm randomized controlled clinical trial

    Prasannan, Dhrushnu / Shindhe, Pradeep S. / Jadar, Prashant G. / Killedar, Ramesh S. / Priyanka K.

    Journal of Ayurveda and Integrative Medicine. 2023 May, June, v. 14, no. 3 p.100719-

    2023  

    Abstract: Ayurveda underlines the significance of wounds and wound healing. Acharya Susruta has highlighted the need for shastiupakramas in the management of the wound. Even with a multitude of therapeutic concepts and formulations in Ayurveda, wound management ... ...

    Abstract Ayurveda underlines the significance of wounds and wound healing. Acharya Susruta has highlighted the need for shastiupakramas in the management of the wound. Even with a multitude of therapeutic concepts and formulations in Ayurveda, wound management has yet to gain acceptance. To evaluate the effect of Jatyadi tulle, Madhughrita tulle, and honey tulle in the management of Shuddhavrana (clean wound). A three-arm randomized, parallel group, active-controlled, open-label clinical trial. Randomization was done through online random number generator software to allocate 45 patients treatment into three groups. Trial groups were treated with Jatyadi tulle (JT), Madhughrita tulle (MG), and control group was treated with Honey tulle (HT) for 10 days, and assessment was done on the 5th and 10th day. The wound was assessed using the Bates Jensen wound assessment tool, and the efficacy of the dressing material was assessed using the Worcestershire tissue viability team dressing assessment form. The study outcomes were early wound healing and clinical cure. Within-group results were assessed using the Wilcoxon matched pairs test, and between-group results were assessed by Kruskal-Wallis ANOVA and Mann-Whitney U test. Significant results were obtained within-group (p value < 0.05) from day 0 and at various time points. The results between groups were found to be comparable; JT and MG were found to be significant in ease of application, removal, and patient comfort. No adverse drug events were identified throughout the study. JT and MG tulle have shown significant results in the management of shuddhavrana.
    Keywords Ayurvedic medicine ; clinical trials ; computer software ; drugs ; honey ; patients ; viability ; wound treatment ; Vrana ; Wound healing ; Jatyadi tulle ; Honey tulle ; Madhughrita tulle
    Language English
    Dates of publication 2023-05
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Use and reproduction
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2023.100719
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: An integrated management (Ayurveda and Modern medicine) of accidental burn injury: A case study.

    Shindhe, Pradeep S / K, Priyanka / Killedar, Ramesh S / Prasannan, Dhrushnu / A, Kirthi

    Journal of Ayurveda and integrative medicine

    2023  Volume 14, Issue 2, Page(s) 100691

    Abstract: Burn injuries are frequent, horrifying, and life-threatening conditions that are still challenging to cure. Complications like scarring, keloid formation, and contractures are the main challenges for the treating surgeon. The Ayurvedic classics explain ... ...

    Abstract Burn injuries are frequent, horrifying, and life-threatening conditions that are still challenging to cure. Complications like scarring, keloid formation, and contractures are the main challenges for the treating surgeon. The Ayurvedic classics explain different treatment modalities for the management of burn wounds, like oral medicines, topical applications prepared with herbal medicines, ghee, oil, and typical wound dressing techniques like Patraadaana (wound covering with medicinal leaves), and fumigation therapy, etc. Here we report a case of accidental burn injury with a TBSA of 27% First degree (superficial) and 15% second degree (deep partial-thickness) burns with complaints of fever and burning sensation at the burn site. On the basis of the symptoms listed in the classical texts of Ayurveda, the case was diagnosed as Pramadadagdha (accidental burn). To properly manage the burn wound, an integrated therapy strategy was designed. Ropanaghrita (medicated ghee) was applied locally, followed by the application of Tinospora cordifolia leaves to cover the wound, fumigation therapy, and oral medications to hasten wound healing and reduce infection. In the first seven days, modern medicine was used as emergency care in addition to Ayurvedic management. Within 60 days of receiving treatment, the burn wound had entirely healed, and the patient was able to resume her regular work activities. In the current situation, the combined strategy produced encouraging burn management outcomes.
    Language English
    Publishing date 2023-02-24
    Publishing country United States
    Document type Case Reports
    ISSN 0975-9476
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2023.100691
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Efficacy of Jatyadi, Madhughrita and honey tulle in wound management: a three-arm randomized controlled clinical trial.

    Prasannan, Dhrushnu / Shindhe, Pradeep S / Jadar, Prashant G / Killedar, Ramesh S / Priyanka K

    Journal of Ayurveda and integrative medicine

    2023  Volume 14, Issue 3, Page(s) 100719

    Abstract: Background: Ayurveda underlines the significance of wounds and wound healing. Acharya Susruta has highlighted the need for shastiupakramas in the management of the wound. Even with a multitude of therapeutic concepts and formulations in Ayurveda, wound ... ...

    Abstract Background: Ayurveda underlines the significance of wounds and wound healing. Acharya Susruta has highlighted the need for shastiupakramas in the management of the wound. Even with a multitude of therapeutic concepts and formulations in Ayurveda, wound management has yet to gain acceptance.
    Objective: To evaluate the effect of Jatyadi tulle, Madhughrita tulle, and honey tulle in the management of Shuddhavrana (clean wound).
    Materials and methods: A three-arm randomized, parallel group, active-controlled, open-label clinical trial. Randomization was done through online random number generator software to allocate 45 patients treatment into three groups. Trial groups were treated with Jatyadi tulle (JT), Madhughrita tulle (MG), and control group was treated with Honey tulle (HT) for 10 days, and assessment was done on the 5th and 10th day. The wound was assessed using the Bates Jensen wound assessment tool, and the efficacy of the dressing material was assessed using the Worcestershire tissue viability team dressing assessment form. The study outcomes were early wound healing and clinical cure.
    Results: Within-group results were assessed using the Wilcoxon matched pairs test, and between-group results were assessed by Kruskal-Wallis ANOVA and Mann-Whitney U test. Significant results were obtained within-group (p value < 0.05) from day 0 and at various time points. The results between groups were found to be comparable; JT and MG were found to be significant in ease of application, removal, and patient comfort. No adverse drug events were identified throughout the study.
    Conclusion: JT and MG tulle have shown significant results in the management of shuddhavrana.
    Language English
    Publishing date 2023-06-02
    Publishing country United States
    Document type Journal Article
    ISSN 0975-9476
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2023.100719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Management of rare, low anal anterior fistula exception to Goodsall's rule with Kṣārasūtra.

    Shindhe, Pradeep S

    Ancient science of life

    2014  Volume 33, Issue 3, Page(s) 182–185

    Abstract: Anal fistula (bhagandara) is a chronic inflammatory condition, a tubular structure opening in the ano-rectal canal at one end and surface of perineum/peri-anal skin on the other end. Typically, fistula has two openings, one internal and other external ... ...

    Abstract Anal fistula (bhagandara) is a chronic inflammatory condition, a tubular structure opening in the ano-rectal canal at one end and surface of perineum/peri-anal skin on the other end. Typically, fistula has two openings, one internal and other external associated with chronic on/off pus discharge on/off pain, pruritis and sometimes passing of stool from external opening. This affects predominantly male patients due to various etiologies viz., repeated peri-anal infections, Crohn's disease, HIV infection, etc., Complex and atypical variety is encountered in very few patients, which require special treatment for cure. The condition poses difficulty for a surgeon in treating due to issues like patient hesitation, trouble in preparing kṣārasūtra, natural and routine infection with urine, stool etc., and dearth of surgical experts and technique. We would like to report a complex and atypical, single case of anterior, low anal fistula with tract reaching to median raphe of scrotum, which was managed successfully by limited application of kṣārasūtra.
    Language English
    Publishing date 2014-12-23
    Publishing country India
    Document type Case Reports
    ZDB-ID 2660395-0
    ISSN 2249-9547 ; 0257-7941
    ISSN (online) 2249-9547
    ISSN 0257-7941
    DOI 10.4103/0257-7941.144624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Wipeout period of spinal anesthesia in hemorrhoidectomy in relation to

    Shindhe, Pradeep S / Pandey, Sudheer Kumar / Killedar, Ramesh

    Ayu

    2018  Volume 38, Issue 3-4, Page(s) 113–116

    Abstract: Background: A maximum number of hemorrhoidectomies are performed under spinal anesthesia. However, the effect of spinal anesthesia varies from person to person due to difference in their physical and psychological properties, which is well explained in ... ...

    Abstract Background: A maximum number of hemorrhoidectomies are performed under spinal anesthesia. However, the effect of spinal anesthesia varies from person to person due to difference in their physical and psychological properties, which is well explained in Ayurveda as
    Objectives: To observe wipeout period of spinal anesthesia in hemorrhoidectomy in relation to different
    Materials and methods: A total of 30 individuals who underwent hemorrhoidectomy under spinal anesthesia were selected for the study and their
    Results: Male predominance was observed in hemorrhoidectomy cases. Majority of the patients were 20-25 years of age with body weight between 61 and 70 kg. Distribution of
    Conclusion: Kapha
    Language English
    Publishing date 2018-09-19
    Publishing country India
    Document type Journal Article
    ISSN 0974-8520
    ISSN 0974-8520
    DOI 10.4103/ayu.AYU_43_17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A case discussion on eczema.

    Hegde, Pallavi / Hemanth, D T / Emmi, S V / Shilpa, M P / Shindhe, Pradeep S / Santosh, Y M

    International journal of Ayurveda research

    2011  Volume 1, Issue 4, Page(s) 268–270

    Abstract: Eczema is a form of dermatitis where inflammation of epidermis occurs. The exact cause of eczema is not known. Although it is activated by the immune system and is related to allergic reactions, it is not the same as other allergic reactions. In Ayurveda, ...

    Abstract Eczema is a form of dermatitis where inflammation of epidermis occurs. The exact cause of eczema is not known. Although it is activated by the immune system and is related to allergic reactions, it is not the same as other allergic reactions. In Ayurveda, the disease is described by the name "Vicharchika." Virechana is the best line of management for skin disorders. Controlling eczema more effectively can make a radical improvement to the patient's quality of life. A case report of 45-year-old male, who presented with complaints of rashes over dorsum of both foot associated with intense itching and burning sensation, oozing wound posterior to lateral malleolus and dorsum of left foot has been presented here.
    Language English
    Publishing date 2011-03-24
    Publishing country India
    Document type Case Reports
    ZDB-ID 2562172-5
    ISSN 0974-925X ; 0974-7788
    ISSN (online) 0974-925X
    ISSN 0974-7788
    DOI 10.4103/0974-7788.76792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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