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  1. Article ; Online: A 37-Year-Old Man With Dyspnea, Bilateral Lung Consolidation, and a Tracheal Mass.

    Shirgaonkar, Rohit / Panigrahi, Manoj Kumar / Girija, Aswathy / Sharma, Prity / Chappity, Preetam / Tripathy, Sagar Ranjan

    Chest

    2024  Volume 165, Issue 1, Page(s) e5–e10

    Abstract: Case presentation: A 37-year-old man presented to the ED with symptoms of productive cough, self-reported fever, and shortness of breath for the past 15 days. He was placed on noninvasive mechanical ventilation for respiratory distress. IV piperacillin- ... ...

    Abstract Case presentation: A 37-year-old man presented to the ED with symptoms of productive cough, self-reported fever, and shortness of breath for the past 15 days. He was placed on noninvasive mechanical ventilation for respiratory distress. IV piperacillin-tazobactam and inhaled bronchodilators were promptly administered, and he was subsequently transferred to the respiratory ICU for further care. He had no history of bowel and bladder disturbance, altered sensorium, swelling of feet, or abdominal distention. He never used tobacco and denied a history of TB. Medical history was notable for recurrent hospitalizations and administration of multiple courses of antibiotics in the past for similar complaints. He often used inhaled bronchodilators/corticosteroids when clinically stable to relieve symptoms.
    MeSH term(s) Male ; Humans ; Adult ; Bronchodilator Agents ; Dyspnea/diagnosis ; Dyspnea/etiology ; Anti-Bacterial Agents/therapeutic use ; Fever ; Lung
    Chemical Substances Bronchodilator Agents ; Anti-Bacterial Agents
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2023.07.065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A lung cyst harbouring a congenital pulmonary varix.

    Moorthy, Akshaya / Shirgaonkar, Rohit / Bal, Shakti Kumar / Patro, Mahismita / Patel, Ranjan Kumar

    BMJ case reports

    2024  Volume 17, Issue 2

    Abstract: A non-smoker man in his second decade presented to a medical centre with intermittent haemoptysis over 2 years. The haemoptysis was infrequent initially to be ignored, but later, the episodes increased in amount and frequency. Routine blood tests ... ...

    Abstract A non-smoker man in his second decade presented to a medical centre with intermittent haemoptysis over 2 years. The haemoptysis was infrequent initially to be ignored, but later, the episodes increased in amount and frequency. Routine blood tests including coagulation profile showed normal results. The chest radiography and echocardiography were normal. The contrast-enhanced CT scan of the chest showed a cystic lesion with intracystic abnormality and surrounding ground-glass opacity in the left upper lobe. The CT pulmonary angiography and invasive pulmonary angiography showed the abnormality to be a dilated pulmonary vessel draining into the left atrium, thereby confirming the diagnosis of congenital pulmonary varix contained within a lung cyst. The patient underwent a successful lobectomy following which he experienced no further haemoptysis.
    MeSH term(s) Male ; Humans ; Hemoptysis/etiology ; Lung/diagnostic imaging ; Lung/surgery ; Lung Diseases/diagnostic imaging ; Lung Diseases/surgery ; Cysts/complications ; Cysts/diagnostic imaging ; Cysts/surgery ; Varicose Veins/congenital
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-259511
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Community-Acquired burkholderia cepacia complex (BCC) pneumonia in a lung cancer patient on erlotinib.

    Mohapatra, Prasanta Raghab / Shirgaonkar, Rohit Bicaro / Behera, Bijayini / Girija, Aswathy

    Lung India : official organ of Indian Chest Society

    2023  Volume 40, Issue 4, Page(s) 364–365

    Abstract: Community-acquired Burkholderia cepacia pneumonia is uncommon. We report a 32-year-old female who was on oral erlotinib, a tyrosine kinase inhibitor, for 2 years for her lung cancer and developed community-acquired Burkholderia cepacia pneumonia, which ... ...

    Abstract Community-acquired Burkholderia cepacia pneumonia is uncommon. We report a 32-year-old female who was on oral erlotinib, a tyrosine kinase inhibitor, for 2 years for her lung cancer and developed community-acquired Burkholderia cepacia pneumonia, which was confirmed by blood culture. The patient improved with antibiotics.
    Language English
    Publishing date 2023-07-07
    Publishing country India
    Document type Journal Article
    ZDB-ID 2410801-7
    ISSN 0974-598X ; 0970-2113
    ISSN (online) 0974-598X
    ISSN 0970-2113
    DOI 10.4103/lungindia.lungindia_57_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Intralobar Pulmonary Sequestration.

    Sarkar, Subho / Girija, Aswathy / Shirgaonkar, Rohit / Mohapatra, Prasanta Raghab

    QJM : monthly journal of the Association of Physicians

    2023  

    Language English
    Publishing date 2023-12-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcad286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Evaluation of Risk Factors for Lung Cancer Among Never Smokers and Their Association With Common Driver Mutations.

    Shirgaonkar, Rohit / Mohapatra, Prasanta R / Panigrahi, Manoj K / Mishra, Pritinanda / Bhuniya, Sourin / Sarkar, Subho / Girija, Aswathy / Shaik, Afshan / Mohanty, Swadesh / Moorthy, Akshaya

    Cureus

    2024  Volume 16, Issue 3, Page(s) e56024

    Abstract: Introduction: The majority of lung cancers are caused by tobacco use, which is linked to lung tumors of all major histological types. A considerable fraction of lung cancer cases, the vast majority of which are adenocarcinomas, occur in "never smokers," ...

    Abstract Introduction: The majority of lung cancers are caused by tobacco use, which is linked to lung tumors of all major histological types. A considerable fraction of lung cancer cases, the vast majority of which are adenocarcinomas, occur in "never smokers," who are characterized as having smoked fewer than 100 cigarettes in their lives. The primary objective was to assess risk factors for lung cancer in non-smokers. In contrast, secondary objectives included evaluating histological subtype, staging, and performance status and exploring associations between risk factors and common driver mutations.
    Material and methods: The study was a single-center, observational, case-control study done at All India Institute of Medical Science, Bhubaneswar, India that focused on non-smokers with lung cancer. It included 145 cases and 297 controls, with statistical analyses such as chi-square tests and logistic regression used to assess associations between risk factors and lung cancer, considering factors such as socioeconomic status, body mass index (BMI), occupation, outdoor and indoor air pollution, personal habits, and medical history.
    Results: The study, comprising 145 lung cancer cases in non-smokers and 297 controls, found that 92.4% (134/145) of cases had adenocarcinoma, 6.9% (10/145) had squamous cell carcinoma, and 0.7% (1/145) had small cell carcinoma. Significant associations were observed for high-risk occupations, indoor biomass use without proper ventilation, low BMI, and family history of lung cancer. Specific pre-existing lung conditions like old pulmonary tuberculosis and asthma were linked to increased and decreased odds of developing lung cancer, respectively. Environmental factors, living near heavy industry, and dietary habits showed significant associations. A significant association was not found between the driver mutations and the risk factors studied.
    Conclusion: This single-center study sheds light on significant risk factors influencing lung cancer development among non-smokers. The predominant occurrence of adenocarcinoma and associations with high-risk occupations, indoor biomass exposure, low BMI, and family history emphasize the multifaceted nature of non-smoking-related lung cancer. The findings underscore the importance of comprehensive risk assessment and targeted preventive strategies in this population.
    Language English
    Publishing date 2024-03-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.56024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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