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  1. Article ; Online: Association between Sleep Duration, Insomnia Symptoms and Bone Mineral Density in Older Boston Puerto Rican Adults.

    Jinya Niu / Shivani Sahni / Susu Liao / Katherine L Tucker / Bess Dawson-Hughes / Xiang Gao

    PLoS ONE, Vol 10, Iss 7, p e

    2015  Volume 0132342

    Abstract: To examine the association between sleep patterns (sleep duration and insomnia symptoms) and total and regional bone mineral density (BMD) among older Boston Puerto Rican adults.We conducted a cross-sectional study including 750 Puerto Rican adults, aged ...

    Abstract To examine the association between sleep patterns (sleep duration and insomnia symptoms) and total and regional bone mineral density (BMD) among older Boston Puerto Rican adults.We conducted a cross-sectional study including 750 Puerto Rican adults, aged 47-79 y living in Massachusetts. BMD at 3 hip sites and the lumbar spine were measured using dual-energy X-ray absorptiometry. Sleep duration (≤5 h, 6 h, 7 h, 8 h, or ≥9 h/d) and insomnia symptoms (difficulty initiating sleep, difficulty maintaining sleep, early-morning awaking, and non-restorative sleep) were assessed by a questionnaire. Multivariable regression was used to examine sex-specific associations between sleep duration, insomnia symptoms and BMD adjusting for standard confounders and covariates.Men who slept ≥9h/d had significantly lower femoral neck BMD, relative to those reporting 8 h/d sleep, after adjusting for age, education level, smoking, physical activity, depressive symptomatology, comorbidity and serum vitamin D concentration. This association was attenuated and lost significance after further adjustment for urinary cortisol and serum inflammation biomarkers. In contrast, the association between sleep duration and BMD was not significant in women. Further, we did not find any significant associations between insomnia symptoms and BMD in men or women.Our study does not support the hypothesis that shorter sleep duration and insomnia symptoms are associated with lower BMD levels in older adults. However, our results should be interpreted with caution. Future studies with larger sample size, objective assessment of sleep pattern, and prospective design are needed before a conclusion regarding sleep and BMD can be reached.
    Keywords Medicine ; R ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Bone Mineral Density and Protein-Derived Food Clusters from the Framingham Offspring Study

    Mangano, Kelsey M / Alyssa B. Dufour / Douglas P. Kiel / Katherine L. Tucker / Marian T. Hannan / Shivani Sahni

    Academy of Nutrition and Dietetics Journal of the Academy of Nutrition and Dietetics. 2015 Oct., v. 115, no. 10

    2015  

    Abstract: Dietary protein is beneficial to bone health; however, dietary patterns of protein intake and their relationship with bone mineral density (BMD) have not been evaluated.To examine the relationship of dietary protein food clusters with BMD at the femoral ... ...

    Abstract Dietary protein is beneficial to bone health; however, dietary patterns of protein intake and their relationship with bone mineral density (BMD) have not been evaluated.To examine the relationship of dietary protein food clusters with BMD at the femoral neck, trochanter, total femur, and lumbar spine among middle-aged and older men and women.Cross-sectional study.Two thousand seven hundred fifty-eight community-dwelling individuals from the Framingham Offspring Study.BMD was measured by Lunar DPX-L (Lunar Radiation Corporation) in 1996-2001. Dietary intakes were estimated using the Willett food frequency questionnaire in either 1995-1998 or 1998-2001, and the exam closest to a participant’s BMD measurement was used. Cluster analysis (FASTCLUS procedure, k-means method) was used to classify participants into groups, determined by major sources of protein. Generalized linear regression was used to compare adjusted least-squares mean BMD across protein food clusters for all pairwise comparisons.From 2,758 participants (44% men; mean age 61±9 years, range=29 to 86 years), five protein food clusters were identified (chicken, fish, processed foods, red meat, and low-fat milk). Three of these food clusters showed associations with BMD. The red meat protein food cluster presented with significantly lower femoral neck BMD compared with the low-fat milk cluster (red meat 0.898±0.005 g/cm2 vs low-fat milk 0.919±0.007 g/cm2; P=0.04). Further, the processed foods protein cluster presented with significantly lower femoral neck BMD compared with the low-fat milk cluster (processed foods 0.897±0.004 g/cm2 vs low-fat milk 0.919±0.007 g/cm2; P=0.02). A similar, yet nonsignificant, trend was observed for other BMD sites examined.Diets with the greatest proportion of protein intake from red meat and processed foods may not be as beneficial to the skeleton compared with dietary patterns where the highest proportion of protein is derived from low-fat milk.
    Keywords bone density ; chickens ; cluster analysis ; eating habits ; femur ; fish ; food frequency questionnaires ; food intake ; least squares ; low fat milk ; lumbar spine ; meat protein ; men ; middle-aged adults ; processed foods ; processed meat ; progeny ; protein intake ; protein sources ; red meat ; skeleton
    Language English
    Dates of publication 2015-10
    Size p. 1605-1613.e1.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 2646718-5
    ISSN 2212-2672
    ISSN 2212-2672
    DOI 10.1016/j.jand.2015.04.001
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Vitamin K intake and mortality in people with chronic kidney disease from NHANES III

    Cheung, Ching-Lung / Bernard M.Y. Cheung / Chor-Wing Sing / Ian C.K. Wong / Shivani Sahni

    Clinical nutrition. 2014,

    2014  

    Abstract: Cardiovascular disease (CVD) is the leading cause of death in patients with chronic kidney disease (CKD), partly due to increased vascular calcification. Vitamin K plays a role in preventing vascular calcification in CKD yet the relationship between ... ...

    Abstract Cardiovascular disease (CVD) is the leading cause of death in patients with chronic kidney disease (CKD), partly due to increased vascular calcification. Vitamin K plays a role in preventing vascular calcification in CKD yet the relationship between vitamin K intake and mortality in CKD patients remains unclear.This observational cohort study included 3401 participants with CKD from the Third National Health and Nutrition Examination Survey. Vitamin K intake was estimated from 24-h dietary recalls (1988–94). Mortality was determined from the National Death Index records through 2006. Cox-proportional hazards regression was used to estimate Hazard Ratios (HR) by comparing those with adequate intake of vitamin K to those with low intake, adjusting for advanced CKD covariates. For sensitivity analysis, these associations were also examined among those with different renal status.During a median follow-up of 13.3 years (37,408 person-years), 1815 and 876 participants died from all-cause and CVD causes, respectively. 72% of the participants had vitamin K intake lower than the recommended adequate intake. Participants with vitamin K intake higher than recommended adequate intake for vitamin K were associated with lower risk of all-cause (HR = 0.85; 95%: 0.72–1; P = 0.047) and CVD mortality (HR = 0.78; 95%: 0.64–95; P = 0.016). Sensitivity analyses in subgroups with advanced CKD revealed similar findings.This observational study suggests that adequate intake of vitamin K may be associated with reduced all-cause and CVD mortality in CKD patients. However, vitamin K may be a marker of a healthy diet; therefore clinical trials may help in clarifying the effect of vitamin K independent of a healthy diet.
    Keywords Adequate Intakes ; calcification ; cardiovascular diseases ; clinical trials ; cohort studies ; death ; diet recall ; healthy diet ; kidney diseases ; mortality ; National Health and Nutrition Examination Survey ; nutrition risk assessment ; observational studies ; patients ; vitamin K
    Language English
    Size p. .
    Publishing place Elsevier Ltd
    Document type Article
    Note Pre-press version
    ZDB-ID 604812-2
    ISSN 1532-1983 ; 0261-5614
    ISSN (online) 1532-1983
    ISSN 0261-5614
    DOI 10.1016/j.clnu.2014.03.011
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

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