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  1. Article ; Online: Electrically polarized TiO

    Bandyopadhyay, Amit / Shivaram, Anish / Mitra, Indranath / Bose, Susmita

    Acta biomaterialia

    2019  Volume 96, Page(s) 686–693

    Abstract: Ti is characteristically bioinert and is supplemented with modifications in surface topography and chemistry to find use in biomedical applications. The aim of this study is to understand the effects of surface charge on ... ...

    Abstract Ti is characteristically bioinert and is supplemented with modifications in surface topography and chemistry to find use in biomedical applications. The aim of this study is to understand the effects of surface charge on TiO
    MeSH term(s) Animals ; Electricity ; Male ; Materials Testing ; Nanotubes/chemistry ; Osseointegration/drug effects ; Prostheses and Implants ; Rats, Sprague-Dawley ; Surface Properties ; Temperature ; Titanium/pharmacology ; X-Ray Diffraction
    Chemical Substances titanium dioxide (15FIX9V2JP) ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2019-07-19
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2173841-5
    ISSN 1878-7568 ; 1742-7061
    ISSN (online) 1878-7568
    ISSN 1742-7061
    DOI 10.1016/j.actbio.2019.07.028
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  2. Article: Direct comparison of additively manufactured porous titanium and tantalum implants towards

    Bandyopadhyay, Amit / Mitra, Indranath / Shivaram, Anish / Dasgupta, Nairanjana / Bose, Susmita

    Additive manufacturing

    2019  Volume 28, Page(s) 259–266

    Abstract: Material properties of implants such as volume porosity and nanoscale surface modification have been shown to enhance cell-material ... ...

    Abstract Material properties of implants such as volume porosity and nanoscale surface modification have been shown to enhance cell-material interactions
    Language English
    Publishing date 2019-05-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2777285-8
    ISSN 2214-8604
    ISSN 2214-8604
    DOI 10.1016/j.addma.2019.04.025
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  3. Article ; Online: Understanding long-term silver release from surface modified porous titanium implants.

    Shivaram, Anish / Bose, Susmita / Bandyopadhyay, Amit

    Acta biomaterialia

    2017  Volume 58, Page(s) 550–560

    Abstract: Prevention of orthopedic device related infection (ODRI) using antibiotics has met with limited amount of success and is still a big concern during post-surgery. As an alternative, use of silver as an antibiotic treatment to prevent surgical infections ... ...

    Abstract Prevention of orthopedic device related infection (ODRI) using antibiotics has met with limited amount of success and is still a big concern during post-surgery. As an alternative, use of silver as an antibiotic treatment to prevent surgical infections is being used due to the well-established antimicrobial properties of silver. However, in most cases silver is used in particulate form with wound dressings or with short-term devices such as catheters but not with load-bearing implants. We hypothesize that strongly adherent silver to load-bearing implants can offer longer term solution to infection in vivo. Keeping that in mind, the focus of this study was to understand the long term release study of silver ions for a period of minimum 6months from silver coated surface modified porous titanium implants. Implants were fabricated using a LENS™ system, a powder based additive manufacturing technique, with at least 25% volume porosity, with and without TiO
    Statement of significance: Prevention of orthopedic device related infection using antibiotics has met with limited success and is still a big concern during post-surgery. Use of silver as an antibiotic treatment to prevent surgical infections is being explored due to the well-established antimicrobial properties of silver. However, in most cases silver is used in particulate form with wound dressings or with short-term devices such as catheters but not with load-bearing implants. We hypothesize that strongly adherent silver to load-bearing implants can offer longer-term solution towards infection in vivo. Keeping that in mind, the focus of this study was to understand the long-term release of silver ions, for a period of minimum 6months, from silver coated surface modified porous titanium implants.
    MeSH term(s) Animals ; Bone Substitutes/chemistry ; Bone Substitutes/pharmacokinetics ; Coated Materials, Biocompatible/pharmacokinetics ; Femur/surgery ; Implants, Experimental/microbiology ; Male ; Porosity ; Rats ; Rats, Sprague-Dawley ; Silver/chemistry ; Silver/pharmacokinetics ; Surgical Wound Infection/prevention & control ; Titanium/chemistry
    Chemical Substances Bone Substitutes ; Coated Materials, Biocompatible ; titanium dioxide (15FIX9V2JP) ; Silver (3M4G523W1G) ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2017-05-29
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2173841-5
    ISSN 1878-7568 ; 1742-7061
    ISSN (online) 1878-7568
    ISSN 1742-7061
    DOI 10.1016/j.actbio.2017.05.048
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  4. Article: Calcium phosphate coated 3D printed porous titanium with nanoscale surface modification for orthopedic and dental applications.

    Bose, Susmita / Banerjee, Dishary / Shivaram, Anish / Tarafder, Solaiman / Bandyopadhyay, Amit

    Materials & design

    2018  Volume 151, Page(s) 102–112

    Abstract: This study aims to improve the interfacial bonding between the osseous host tissue and the implant surface through the application of doped calcium phosphate (CaP) coating on 3D printed porous titanium. Porous titanium (Ti) cylinders with 25% volume ... ...

    Abstract This study aims to improve the interfacial bonding between the osseous host tissue and the implant surface through the application of doped calcium phosphate (CaP) coating on 3D printed porous titanium. Porous titanium (Ti) cylinders with 25% volume porosity were fabricated using Laser Engineered Net Shaping (LENS™), a commercial 3D Printing technique. The surface of these 3D printed cylinders was modified by growing TiO
    Language English
    Publishing date 2018-04-18
    Publishing country England
    Document type Journal Article
    ISSN 0264-1275
    ISSN 0264-1275
    DOI 10.1016/j.matdes.2018.04.049
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  5. Article ; Online: Mechanical degradation of TiO2 nanotubes with and without nanoparticulate silver coating.

    Shivaram, Anish / Bose, Susmita / Bandyopadhyay, Amit

    Journal of the mechanical behavior of biomedical materials

    2016  Volume 59, Page(s) 508–518

    Abstract: The primary objective of this research was to evaluate the extent of mechanical degradation on TiO2 nanotubes on Ti with and without nano-particulate silver coating using two different lengths of TiO2 nanotubes-300nm and ~1µm, which were fabricated on ... ...

    Abstract The primary objective of this research was to evaluate the extent of mechanical degradation on TiO2 nanotubes on Ti with and without nano-particulate silver coating using two different lengths of TiO2 nanotubes-300nm and ~1µm, which were fabricated on commercially pure Titanium (cp-Ti) rods using anodization method using two different electrolytic mediums-(1) deionized (DI) water with 1% HF, and (2) ethylene glycol with 1% HF, 0.5wt% NH4F and 10% DI water. Nanotubes fabricated rods were implanted into equine cadaver bone to evaluate mechanical damage at the surface. Silver was electrochemically deposited on these nanotubes and using a release study, silver ion concentrations were measured before and after implantation, followed by surface characterization using a Field Emission Scanning Electron Microscope (FESEM). In vitro cell-material interaction study was performed using human fetal osteoblast cells (hFOB) to understand the effect of silver coating using an MTT assay for proliferation and to determine any cytotoxic effect on the cells and to study its biocompatibility. No significant damage due to implantation was observed for nanotubes up to ~1µm length under current experimental conditions. Cell-materials interaction showed no cytotoxic effects on the cells due to silver coating and anodization of samples.
    Language English
    Publishing date 2016-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2378381-3
    ISSN 1878-0180 ; 1751-6161
    ISSN (online) 1878-0180
    ISSN 1751-6161
    DOI 10.1016/j.jmbbm.2016.02.028
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  6. Article: Additively manufactured calcium phosphate reinforced CoCrMo alloy: Bio-tribological and biocompatibility evaluation for load-bearing implants.

    Bandyopadhyay, Amit / Shivaram, Anish / Isik, Murat / Avila, Jose D / Dernell, William S / Bose, Susmita

    Additive manufacturing

    2019  Volume 28, Page(s) 312–324

    Abstract: Cobalt-chromium-molybdenum (CoCrMo) alloys are widely used in load-bearing implants; specifically, in hip, knee, and spinal applications due to their excellent wear resistance. However, due ... ...

    Abstract Cobalt-chromium-molybdenum (CoCrMo) alloys are widely used in load-bearing implants; specifically, in hip, knee, and spinal applications due to their excellent wear resistance. However, due to
    Language English
    Publishing date 2019-05-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2777285-8
    ISSN 2214-8604
    ISSN 2214-8604
    DOI 10.1016/j.addma.2019.04.020
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  7. Article ; Online: Silver nanoparticle deposited implants to treat osteomyelitis.

    Nandi, Samit Kumar / Shivaram, Anish / Bose, Susmita / Bandyopadhyay, Amit

    Journal of biomedical materials research. Part B, Applied biomaterials

    2017  Volume 106, Issue 3, Page(s) 1073–1083

    Abstract: In this study, electrolytically deposited strongly adherent silver nanoparticles on stainless-steel (SS) implants were used for in situ osteomyelitis treatment. Samples were heat treated to enhance adhesion of silver on 316 L SS. Ex vivo studies were ... ...

    Abstract In this study, electrolytically deposited strongly adherent silver nanoparticles on stainless-steel (SS) implants were used for in situ osteomyelitis treatment. Samples were heat treated to enhance adhesion of silver on 316 L SS. Ex vivo studies were performed to measure silver-release profiles from the 316 L SS screws inserted in equine cadaver bones. No change in the release profiles of silver ions were observed in vitro between the implanted screws and the control. In vivo studies were performed using osteomyelitic rabbit model with 3 mm diameter silver-deposited 316 L SS pins at two different doses of silver: high and low. Infection control ability of the pins for treating osteomyelitis in a rabbit model was measured using bacteriologic, radiographic, histological, and scanning electron microscopic studies. Silver-coated pins, especially high dose, offered a promising result to treat infection in animal osteomyelitis model without any toxicity to major organs. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1073-1083, 2018.
    MeSH term(s) Animals ; Bone Screws ; Coated Materials, Biocompatible ; Metal Nanoparticles/adverse effects ; Metal Nanoparticles/chemistry ; Metal Nanoparticles/therapeutic use ; Nanoparticles ; Osteomyelitis/microbiology ; Osteomyelitis/prevention & control ; Prostheses and Implants ; Prosthesis-Related Infections/microbiology ; Prosthesis-Related Infections/prevention & control ; Rabbits ; Silver/adverse effects ; Silver/chemistry ; Silver/therapeutic use ; Staphylococcal Infections/microbiology ; Staphylococcal Infections/prevention & control ; Staphylococcus aureus/drug effects
    Chemical Substances Coated Materials, Biocompatible ; Silver (3M4G523W1G)
    Language English
    Publishing date 2017-05-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2099992-6
    ISSN 1552-4981 ; 1552-4973 ; 0021-9304
    ISSN (online) 1552-4981
    ISSN 1552-4973 ; 0021-9304
    DOI 10.1002/jbm.b.33910
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6196: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: In Vivo Response of Laser Processed Porous Titanium Implants for Load-Bearing Implants.

    Bandyopadhyay, Amit / Shivaram, Anish / Tarafder, Solaiman / Sahasrabudhe, Himanshu / Banerjee, Dishary / Bose, Susmita

    Annals of biomedical engineering

    2017  Volume 45, Issue 1, Page(s) 249–260

    Abstract: Applications of porous metallic implants to enhance osseointegration of load-bearing implants are increasing. In this work, porous titanium implants, with 25 vol.% porosity, were manufactured using Laser Engineered Net Shaping (LENS™) to measure the ... ...

    Abstract Applications of porous metallic implants to enhance osseointegration of load-bearing implants are increasing. In this work, porous titanium implants, with 25 vol.% porosity, were manufactured using Laser Engineered Net Shaping (LENS™) to measure the influence of porosity towards bone tissue integration in vivo. Surfaces of the LENS™ processed porous Ti implants were further modified with TiO
    MeSH term(s) Animals ; Implants, Experimental ; Lasers ; Male ; Materials Testing ; Nanotubes/chemistry ; Porosity ; Rats ; Rats, Sprague-Dawley ; Titanium/chemistry ; Titanium/pharmacology ; Weight-Bearing ; X-Ray Microtomography
    Chemical Substances titanium dioxide (15FIX9V2JP) ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2017-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 185984-5
    ISSN 1573-9686 ; 0191-5649 ; 0090-6964
    ISSN (online) 1573-9686
    ISSN 0191-5649 ; 0090-6964
    DOI 10.1007/s10439-016-1673-8
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1018: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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