Article: Antiosteoarthritis activities of 70% ethanol extract of
Journal of public health in Africa
2023 Volume 14, Issue Suppl 1, Page(s) 2506
Abstract: Background: Osteoarthritis (OA) is a common degenerative joint situation that induces pain and disability in the elderly. Traditionally, : Objective: In this research, we employed an : Methods: A singular intraarticular injection of Monosodium ... ...
| Abstract | Background: Osteoarthritis (OA) is a common degenerative joint situation that induces pain and disability in the elderly. Traditionally, Objective: In this research, we employed an Methods: A singular intraarticular injection of Monosodium Iodoacetate (MIA) was used to create the OA model in rats. The progression of OA was observed for three weeks. Furthermore, treatment of EBE at a dose of 6, 12, and 24 mg/200g BW orally for four weeks was conducted to assess the effects on decreasing IL- 1. level, joint swelling, and hyperalgesia. Results: Induction was successful, indicated by a significant difference (P<0.05) in decreasing latency time, increasing joint swelling, and IL-1. level. EBE 24 mg/200 g BW treatment has significantly (P<0.05) reduced IL-1. levels, joint swelling, and response to hyperalgesia. Conclusion: The 70% ethanol extract of |
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| Language | English |
| Publishing date | 2023-03-16 |
| Publishing country | Italy |
| Document type | Journal Article |
| ZDB-ID | 2574977-8 |
| ISSN | 2038-9930 ; 2038-9922 |
| ISSN (online) | 2038-9930 |
| ISSN | 2038-9922 |
| DOI | 10.4081/jphia.2023.2506 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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