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Artikel ; Online: The causal association between sarcopenia and colorectal cancer

Shu Ran / Min-Fei Zhao / Bao-Lin Liu

The Korean Journal of Internal Medicine, Vol 38, Iss 2, Pp 266-

a Mendelian Randomization analysis

2023 Band 268

Schlagwörter	Medicine ; R
Sprache	Englisch
Erscheinungsdatum	2023-03-01T00:00:00Z
Verlag	The Korean Association of Internal Medicine
Dokumenttyp	Artikel ; Online
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Artikel ; Online: Extraction of Music Main Melody and Multi-Pitch Estimation Method Based on Support Vector Machine in Big Data Environment.

Liang, Shaoru / Shu, Ran

Publikation ZURÜCKGEZOGEN

Journal of environmental and public health

2022 Band 2022, Seite(n) 1074174

Abstract: Main melody extraction and multi-pitch estimation are two important research topics in the MIR field. In this article, the SVM algorithm is used to analyze and discuss music melody extraction and multi-pitch estimation. In the part of multi-fundamental ... ...

Abstract	Main melody extraction and multi-pitch estimation are two important research topics in the MIR field. In this article, the SVM algorithm is used to analyze and discuss music melody extraction and multi-pitch estimation. In the part of multi-fundamental frequency extraction, this article first filters the song signal with equal loudness and weakens the energy of the high-frequency and low-frequency parts of the song signal. Thereafter, the multi-resolution short-time Fourier transform suitable for processing song signals is introduced. In addition, in order to avoid the sharp jump of the estimated melody pitch in the same note duration range, this article proposes a main melody extraction method combining the SVM algorithm with dynamic programming. In this article, more features are used to distinguish the pitch contour of vocal fundamental frequency from that of the nonvocal fundamental frequency, which does not only depend on energy or a certain feature. The experimental results show that the lowest octave error of this method is 1.46. Meanwhile, the recall rate of the algorithm can reach about 95%. This method not only improves the recall rate of the fundamental frequency of the human voice but also improves the recall rate and pitch accuracy rate of the whole main melody extraction system.
Mesh-Begriff(e)	Big Data ; Humans ; Mental Recall ; Music ; Support Vector Machine
Sprache	Englisch
Erscheinungsdatum	2022-08-31
Erscheinungsland	United States
Dokumenttyp	Journal Article ; Retracted Publication
ZDB-ID	2526611-1
ISSN	1687-9813 ; 1687-9813
ISSN (online)	1687-9813
ISSN	1687-9813
DOI	10.1155/2022/1074174
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Can nesting behaviour allow reptiles to adapt to climate change?

Du, Wei-Guo / Li, Shu-Ran / Sun, Bao-Jun / Shine, Richard

Philosophical transactions of the Royal Society of London. Series B, Biological sciences

2023 Band 378, Heft 1884, Seite(n) 20220153

Abstract: A range of abiotic parameters within a reptile nest influence the viability and attributes (including sex, behaviour and body size) of hatchlings that emerge from that nest. As a result of that sensitivity, a reproducing female can manipulate the ... ...

Abstract	A range of abiotic parameters within a reptile nest influence the viability and attributes (including sex, behaviour and body size) of hatchlings that emerge from that nest. As a result of that sensitivity, a reproducing female can manipulate the phenotypic attributes of her offspring by laying her eggs at times and in places that provide specific conditions. Nesting reptiles shift their behaviour in terms of timing of oviposition, nest location and depth of eggs beneath the soil surface across spatial and temporal gradients. Those maternal manipulations affect mean values and variances of both temperature and soil moisture, and may modify the vulnerability of embryos to threats such as predation and parasitism. By altering thermal and hydric conditions in reptile nests, climate change has the potential to dramatically modify the developmental trajectories and survival rates of embryos, and the phenotypes of hatchlings. Reproducing females buffer such effects by modifying the timing, location and structure of nests in ways that enhance offspring viability. Nonetheless, our understanding of nesting behaviours in response to climate change remains limited in reptiles. Priority topics for future studies include documenting climate-induced changes in the nest environment, the degree to which maternal behavioural shifts can mitigate climate-related deleterious impacts on offspring development, and ecological and evolutionary consequences of maternal nesting responses to climate change. This article is part of the theme issue 'The evolutionary ecology of nests: a cross-taxon approach'.
Mesh-Begriff(e)	Animals ; Female ; Nesting Behavior/physiology ; Climate Change ; Reptiles ; Adaptation, Physiological ; Temperature ; Soil
Chemische Substanzen	Soil
Sprache	Englisch
Erscheinungsdatum	2023-07-10
Erscheinungsland	England
Dokumenttyp	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	208382-6
ISSN	1471-2970 ; 0080-4622 ; 0264-3839 ; 0962-8436
ISSN (online)	1471-2970
ISSN	0080-4622 ; 0264-3839 ; 0962-8436
DOI	10.1098/rstb.2022.0153
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Qualitative analysis on the transdermal absorption from the dichloromethane extract of the Sambucus adnata wall. based on UPLC-Q-Exactive Orbitrap/MS.

Qin, Shu-Ran / Wang, Wei / Li, Dashan / Pu, Yue-Fei / Cui, Tao / Wang, Wen-Jing

Journal of pharmaceutical and biomedical analysis

2023 Band 234, Seite(n) 115509

Abstract: Sambucus adnata Wall.(SAW) has been used to treat osteoarthritis by the Yi nationality in China. The present study established an overall identification strategy based on ultra-high performance liquid chromatography-tandem Q-Exactive Orbitrap mass ... ...

Abstract	Sambucus adnata Wall.(SAW) has been used to treat osteoarthritis by the Yi nationality in China. The present study established an overall identification strategy based on ultra-high performance liquid chromatography-tandem Q-Exactive Orbitrap mass spectrometry (UPLC-Q-Exactive Orbitrap/MS) method to characterize the multiple chemical constituents of SAW before and after percutaneous penetration. Nineteen compounds, including triterpenoids, fatty acids, lignans, flavonoid, and amide, were tentatively identified in the dichloromethane extract of SAW, while fourteen ingredients penetrated the skin. Among them, eleven components were reported for the first time in SAW.
Mesh-Begriff(e)	Methylene Chloride ; Skin Absorption ; Mass Spectrometry/methods ; Chromatography, High Pressure Liquid/methods ; Drugs, Chinese Herbal/chemistry
Chemische Substanzen	Methylene Chloride (588X2YUY0A) ; Drugs, Chinese Herbal
Sprache	Englisch
Erscheinungsdatum	2023-06-12
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	604917-5
ISSN	1873-264X ; 0731-7085
ISSN (online)	1873-264X
ISSN	0731-7085
DOI	10.1016/j.jpba.2023.115509
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Case report on gynecomastia with ipsilateral recurrence of granulomatous lobular mastitis.

Han, Yao Ke / Ting, Wang / Ting, Pan / Yv, Xiao Bing / Xi, Shu Ran / Gang, Lyu

The Journal of international medical research

2023 Band 51, Heft 7, Seite(n) 3000605231187815

Abstract: This study describes a rare case of male granulomatous lobular mastitis (GLM) with recurrence in different sites on the ipsilateral side. A 48-year-old male patient presented with no previous history of breast-related disease, and physical examination ... ...

Abstract	This study describes a rare case of male granulomatous lobular mastitis (GLM) with recurrence in different sites on the ipsilateral side. A 48-year-old male patient presented with no previous history of breast-related disease, and physical examination suggested a mass in the right breast. Ultrasonography revealed a cyst and infection in the right breast. No obvious abnormality was found in laboratory analysis, and a core needle biopsy revealed GLM. Incision and drainage were applied to the right lesion, and symptoms resolved within a few weeks. At 2 years following this initial presentation, the patient reported that the right breast mass reappeared in different locations after the consumption of alcohol. Relevant examination and a core needle biopsy again suggested GLM of the right breast. The patient declined hormone therapy and was subsequently lost to follow-up. After reviewing this case, the course of the disease in this patient, and the connection between gynecomastia and GLM, along with ipsilateral recurrence, are under investigation.
Mesh-Begriff(e)	Female ; Male ; Humans ; Middle Aged ; Gynecomastia/diagnostic imaging ; Gynecomastia/surgery ; Gynecomastia/pathology ; Neoplasm Recurrence, Local/pathology ; Granulomatous Mastitis/diagnostic imaging ; Granulomatous Mastitis/surgery ; Breast ; Breast Diseases ; Recurrence
Sprache	Englisch
Erscheinungsdatum	2023-07-31
Erscheinungsland	England
Dokumenttyp	Case Reports ; Journal Article
ZDB-ID	184023-x
ISSN	1473-2300 ; 0300-0605 ; 0142-2596
ISSN (online)	1473-2300
ISSN	0300-0605 ; 0142-2596
DOI	10.1177/03000605231187815
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Complete mitochondrial genome of Stethoconus japonicus (Hemiptera: Miridae): Insights into the evolutionary traits within the family Miridae.

Chen, Shi-Chun / Jiang, Hong-Yan / Liao, Shu-Ran / Chen, Ting-Xu / Wang, Xiao-Qing

Gene

2023 Band 891, Seite(n) 147830

Abstract: The mitochondrial (mt) genome sequence of insects possesses numerous evolutionary traits. To better understand the evolution of mt genomes within the family Miridae, the complete mt genome of the predatory Japanese plant bug Stethoconus japonicus ... ...

Abstract	The mitochondrial (mt) genome sequence of insects possesses numerous evolutionary traits. To better understand the evolution of mt genomes within the family Miridae, the complete mt genome of the predatory Japanese plant bug Stethoconus japonicus Schumacher was sequenced before undertaking a comparative analysis of all reported plant bug mt genomes. The mt genome of S. japonicus is a closed-circular and double-stranded DNA molecule of 16,274 bp (GenBank: MK341530), which consists of 13 protein-coding genes (PCGs), 2 rRNAs, 22 tRNAs and a putative control region (CR). Consistent with other plant bugs, the mt genome of S. japonicus is strongly AT-biased (73.49 %) with A-skewed (0.202) and C-skewed (-0.248). All 13 PCGs initiate translation using ATN codons and TAA served as complete stop codons for eight PCGs, which as incomplete stop codon "T-" for cox1, nad1, nad5-6 and "TA-" for cox2. Regarding other features, all 22 tRNAs could be folded into typical cloverleaf secondary structures. The control region is 1,717 bp and contains a long tandem repeat sequence of a 165 bp unit repeated six times. Similar sequence with variable number of tandemly repeated units from intra-genus CRs is a distinct characteristic of plant bug mt genomes. Phylogenetic relationships of 15 bugs were eventually analyzed based on Maximum likelihood (ML) and Bayesian inference (BI) methods using 17 mt genome sequences. In the phylogenetic trees, species from a same genus or subfamily are clustered into a branch with high supporting values.and the result suggest that Deraeocorinae is more closely related to Mirinae than Bryocorinae. Finally, this study revealed that mutation of tRNA anticodon is a useful phylogenetic marker that could be of significance for studies of evolutionary patterns.
Mesh-Begriff(e)	Animals ; Genome, Mitochondrial ; Phylogeny ; Bayes Theorem ; Heteroptera/genetics ; Codon, Terminator/genetics ; RNA, Transfer/genetics ; RNA, Transfer/chemistry
Chemische Substanzen	Codon, Terminator ; RNA, Transfer (9014-25-9)
Sprache	Englisch
Erscheinungsdatum	2023-09-25
Erscheinungsland	Netherlands
Dokumenttyp	Journal Article
ZDB-ID	391792-7
ISSN	1879-0038 ; 0378-1119
ISSN (online)	1879-0038
ISSN	0378-1119
DOI	10.1016/j.gene.2023.147830
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Response of Soil Microbial Community Structure Mediated by Sulfur-Induced Resistance Against Kiwifruit Bacterial Canker.

Yang, Sen / Shu, Ran / Yin, Xianhui / Long, Youhua / Yuan, Jun

Frontiers in microbiology

2022 Band 13, Seite(n) 883463

Abstract: Kiwifruit bacterial canker caused ... ...

Abstract	Kiwifruit bacterial canker caused by
Sprache	Englisch
Erscheinungsdatum	2022-05-30
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2022.883463
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Enhanced metagenomic deep learning for disease prediction and consistent signature recognition by restructured microbiome 2D representations.

Shen, Wan Xiang / Liang, Shu Ran / Jiang, Yu Yang / Chen, Yu Zong

Patterns (New York, N.Y.)

2022 Band 4, Heft 1, Seite(n) 100658

Abstract: Metagenomic analysis has been explored for disease diagnosis and biomarker discovery. Low sample sizes, high dimensionality, and sparsity of metagenomic data challenge metagenomic investigations. Here, an unsupervised microbial embedding, grouping, and ... ...

Abstract	Metagenomic analysis has been explored for disease diagnosis and biomarker discovery. Low sample sizes, high dimensionality, and sparsity of metagenomic data challenge metagenomic investigations. Here, an unsupervised microbial embedding, grouping, and mapping algorithm (MEGMA) was developed to transform metagenomic data into individualized multichannel microbiome 2D representation by manifold learning and clustering of microbial profiles (e.g., composition, abundance, hierarchy, and taxonomy). These 2D representations enable enhanced disease prediction by established ConvNet-based AggMapNet models, outperforming the commonly used machine learning and deep learning models in metagenomic benchmark datasets. These 2D representations combined with AggMapNet explainable module robustly identified more reliable and replicable disease-prediction microbes (biomarkers). Employing the MEGMA-AggMapNet pipeline for biomarker identification from 5 disease datasets, 84% of the identified biomarkers have been described in over 74 distinct works as important for these diseases. Moreover, the method also discovered highly consistent sets of biomarkers in cross-cohort colorectal cancer (CRC) patients and microbial shifts in different CRC stages.
Sprache	Englisch
Erscheinungsdatum	2022-12-15
Erscheinungsland	United States
Dokumenttyp	Journal Article
ISSN	2666-3899
ISSN (online)	2666-3899
DOI	10.1016/j.patter.2022.100658
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Detection and Control of

Shu, Ran / Yin, Xianhui / Long, Youhua / Yuan, Jun / Zhou, Houyin

Frontiers in microbiology

2022 Band 13, Seite(n) 896567

Abstract: Plum bacterial shot-hole caused ... ...

Abstract	Plum bacterial shot-hole caused by
Sprache	Englisch
Erscheinungsdatum	2022-05-25
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2022.896567
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Tamoxifen inhibits TGF-β/Smad pathway and reduces pathological proliferation of human dermal fibroblasts

SHI Chun-tian / MAO Shu-ran / PENG Yi-xuan / XIAO Zhi-bo

Jichu yixue yu linchuang, Vol 42, Iss 9, Pp 1367-

2022 Band 1373

Abstract: Objective To explore the function and mechanism of tamoxifen, an estrogen receptor modulator, in the pathogenesis of hyperplatic scar. Methods Primary human fibroblasts were isolated and cultured for 4 generations and then aliquated into 3 groups: ... ...

Abstract	Objective To explore the function and mechanism of tamoxifen, an estrogen receptor modulator, in the pathogenesis of hyperplatic scar. Methods Primary human fibroblasts were isolated and cultured for 4 generations and then aliquated into 3 groups: control group, TGF-β1 group and TGF-β1+ tamoxifen group. The effects of tamoxifen on human fibrogenic factor production, cell proliferation, migration and differentiation of TGF-β1-induced skin fibroblasts were detected by real-time quantitative polymerase chain reaction (RT-qPCR), MTS, cell scratch test, Western blot and immunofluorescence assay. Results Tamoxifen (10 μmol/L) inhibited the production of collagen 1, collagen 3 and α-SMA induced by TGF-β1 in fibroblasts. MTS results showed that the proliferation activity of TGF-β1 group was higher than that of tamoxifen group (P＜0.05). Wound healing test verified that the migration ability of cells was reduced by tamoxifen intervention. Tamoxifen inhibited collagen secretion and differentiation of skin fibroblasts into muscle fibroblasts. Conclusions The estrogen receptor modulator tamoxifen inhibits pathological proliferation of fibroblasts, so it may be a potential novel strategy for the treatment of hyperplastic scar.
Schlagwörter	hyperplastic scar\| tamoxifen\| tgf-β\| skin fibroblasts ; Medicine ; R
Thema/Rubrik (Code)	500
Sprache	Chinesisch
Erscheinungsdatum	2022-09-01T00:00:00Z
Verlag	Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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