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  1. Article ; Online: Research on the Sound Insulation Performance of Composite Rubber Reinforced with Hollow Glass Microsphere Based on Acoustic Finite Element Simulation

    Xiaocui Yang / Shuai Tang / Xinmin Shen / Wenqiang Peng

    Polymers, Vol 15, Iss 611, p

    2023  Volume 611

    Abstract: The composite rubber reinforced with hollow glass microsphere (HGM) was a promising composite material for noise reduction, and its sound insulation mechanism was studied based on an acoustic finite element simulation to gain the appropriate parameter ... ...

    Abstract The composite rubber reinforced with hollow glass microsphere (HGM) was a promising composite material for noise reduction, and its sound insulation mechanism was studied based on an acoustic finite element simulation to gain the appropriate parameter with certain constraint conditions. The built simulation model included the air domain, polymer domain and inorganic particles domain. The sound insulation mechanism of the composite material was investigated through distributions of the sound pressure and sound pressure level. The influences of the parameters on the sound transmission loss (STL) were researched one by one, such as the densities of the composite rubber and HGM, the acoustic velocities in the polymer and inorganic particle, the frequency of the incident wave, the thickness of the sound insulator, and the diameter, volume ratio and hollow ratio of the HGM. The weighted STL with the 1/3 octave band was treated as the evaluation criterion to compare the sound insulation property with the various parameters. For the limited thicknesses of 1 mm, 2 mm, 3 mm and 4 mm, the corresponding optimal weighted STL of the composite material reached 14.02 dB, 19.88 dB, 22.838 dB and 25.27 dB with the selected parameters, which exhibited an excellent sound insulation performance and could promote the practical applications of the proposed composite rubber reinforced with HGM.
    Keywords composite rubber ; hollow glass microsphere ; acoustic finite element simulation ; sound insulation mechanism ; sound transmission loss ; sound pressure level ; Organic chemistry ; QD241-441
    Subject code 621
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: A three-dimensional experimental study on bank retreat

    Keyu Wang / Zheng Gong / Kun Zhao / Shuai Tang / Kaili Zhang

    Frontiers in Marine Science, Vol

    The coupled role of seepage and surface flow

    2022  Volume 9

    Abstract: The coupled role of seepage and surface flow on bank retreat has long been neglected, partly due to the concealment and complexity of seepage erosion. To fill this gap, we set up a three-dimensional laboratory experiment to explore bank retreat process ... ...

    Abstract The coupled role of seepage and surface flow on bank retreat has long been neglected, partly due to the concealment and complexity of seepage erosion. To fill this gap, we set up a three-dimensional laboratory experiment to explore bank retreat process in response to seepage and surface flow. During each experiment, we measured the changes of total soil stress, matric suction, and water content within the bank, as well as flow velocity and suspended sediment concentration near the bank. Results show that a rapid decrease in matric suction, the bank toe undercutting consequent to seepage erosion, the formation of tension crack on the bank top, and the occurrence of toppling or shear failure is the typical sequence of the observed bank retreat process under seepage flow. The inclusion of surface flow erodes slump blocks and so promotes cantilever formation, leading to additional bank failure. Compared with the case where only seepage is considered, the frequency of toppling failure under the coupled effect of seepage and surface flow decreases, but the contribution to the bank retreat increases by 37 %. The time taken to collapse in three-dimensional experiments is at least 1.5 h earlier than that of two-dimensional experiments, indicating the importance of preferential flow pathways of seepage. Overall, this research illustrates how surface flow interacts with seepage flow to control bank retreat process and is indeed a first step toward a fully understanding of multifactor-driven bank retreat.
    Keywords bank retreat ; bank collapse ; seepage ; matric suction ; surface flow ; Science ; Q ; General. Including nature conservation ; geographical distribution ; QH1-199.5
    Subject code 170
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: HIF-1α-Overexpressing Mesenchymal Stem Cells Attenuate Colitis by Regulating M1-like Macrophages Polarization toward M2-like Macrophages

    Wenya Zhu / Qianqian Chen / Yi Li / Jun Wan / Jia Li / Shuai Tang

    Biomedicines, Vol 11, Iss 825, p

    2023  Volume 825

    Abstract: A modified mesenchymal stem cell (MSC) transplantation is a highly effective and precise treatment for inflammatory bowel disease (IBD), with a significant curative effect. Thus, we aim to examine the efficacy of hypoxia-inducible factor (HIF)–1α- ... ...

    Abstract A modified mesenchymal stem cell (MSC) transplantation is a highly effective and precise treatment for inflammatory bowel disease (IBD), with a significant curative effect. Thus, we aim to examine the efficacy of hypoxia-inducible factor (HIF)–1α-overexpressing MSC (HIF-MSC) transplantation in experimental colitis and investigate the immunity regulation mechanisms of HIF-MSC through macrophages. A chronic experimental colitis mouse model was established using 2,4,6-trinitrobenzene sulfonic acid. HIF-MSC transplantation significantly attenuated colitis in weight loss rate, disease activity index (DAI), colon length, and pathology score and effectively rebuilt the local and systemic immune balance. Macrophage depletion significantly impaired the benefits of HIF-MSCs on mice with colitis. Immunofluorescence analysis revealed that HIF-MSCs significantly decreased the number of M1-like macrophages and increased the number of M2-like macrophages in colon tissues. In vitro, co-culturing with HIF-MSCs significantly decreased the expression of pro-inflammatory factors, C-C chemokine receptor 7 (CCR-7), and inducible nitric oxide synthase (INOS) and increased the expression of anti-inflammatory factors and arginase I (Arg-1) in induced M1-like macrophages. Flow cytometry revealed that co-culturing with HIF-MSCs led to a decrease in the proportions of M1-like macrophages and an increase in that of M2-like macrophages. HIF-MSCs treatment notably upregulated the expression of downstream molecular targets of phosphatidylinositol 3-kinase-γ (PI3K-γ), including HIF-1α and p-AKT/AKT in the colon tissue. A selected PI3K-γ inhibitor, IPI549, attenuated these effects, as well as the effect on M2-like macrophage polarization and inflammatory cytokines in colitis mice. In vitro, HIF-MSCs notably upregulated the expression of C/EBPβ and AKT1/AKT2, and PI3K-γ inhibition blocked this effect. Modified MSCs stably overexpressed HIF-1α, which effectively regulated macrophage polarization through PI3K-γ. HIF-MSC transplantation may be a ...
    Keywords mesenchymal stem cells ; hypoxia-inducible factor1α ; colitis ; immunoregulation ; macrophages ; phosphatidylinositol 3-kinase-γ ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: A novel model compression method based on joint distillation for deepfake video detection

    Xiong Xu / Shuai Tang / Mingcheng Zhu / Peisong He / Sirui Li / Yun Cao

    Journal of King Saud University: Computer and Information Sciences, Vol 35, Iss 9, Pp 101792- (2023)

    2023  

    Abstract: In recent years, deepfake videos have been abused to create fake news, which threaten the integrity of digital videos. Although existing detection methods leveraged cumbersome neural networks to achieve promising detection performance, they cannot be ... ...

    Abstract In recent years, deepfake videos have been abused to create fake news, which threaten the integrity of digital videos. Although existing detection methods leveraged cumbersome neural networks to achieve promising detection performance, they cannot be deployed in resource-constrained scenarios. To overcome this limitation, we propose a novel model compression framework based on joint distillation for deepfake detection, which includes a pre-training stage and a knowledge transfer stage. In the pre-training stage, a teacher network is trained with sufficient labeled samples. Then, in the knowledge transfer stage, a lightweight student network is constructed by considering dimension alignment. To transfer forensics knowledge comprehensively, a joint distillation loss is designed, including cross-entropy loss, knowledge distillation loss, and gradient-guided feature distillation loss. For feature distillation, feature maps from both shallow and deep layers are utilized to calculate channel-wise mean square error weighted by gradient information for transferring knowledge of forensics features adaptively. Besides, a decayed teaching strategy is constructed to adjust the importance of feature distillation, which aims at mitigating the risk of negative transfer. Extensive experiments show that student networks obtained by our model compression method can achieve competitive detection performance and outstanding efficiency by distinctly reducing computational costs compared against state-of-the-art methods.
    Keywords Video forensics ; Deepfake detection ; Model compression ; Joint distillation ; Gradient-guided feature distillation ; Decayed teaching strategy ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 004
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Reduction in Work Functions of Transition-Metal Carbides and Oxycarbides upon Oxidation

    Wataru Hayami / Shuai Tang / Ta-Wei Chiu / Jie Tang

    ACS Omega, Vol 6, Iss 22, Pp 14559-

    2021  Volume 14565

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Correlation between bilateral GFR in patients with localized renal cancer after partial nephrectomy.

    Wensong, Wu / Fan, Chang / Jianghui, Zhang / Shuai, Tang / Zheng, Lv / Xuehui, Liu / Fangmin, Chen

    International urology and nephrology

    2023  Volume 56, Issue 5, Page(s) 1617–1625

    Abstract: Objective: To explore the relationship between the residual glomerular filtration rate (GFR) on the operated side and the GFR on the contralateral side following partial nephrectomy (PN) in patients with localized renal cell carcinoma (RCC).: ... ...

    Abstract Objective: To explore the relationship between the residual glomerular filtration rate (GFR) on the operated side and the GFR on the contralateral side following partial nephrectomy (PN) in patients with localized renal cell carcinoma (RCC).
    Materials and methods: Following institutional review board approval, we conducted a retrospective analysis of clinical records from May 2018 to July 2023, involving 118 patients who underwent partial nephrectomy for unilateral localized kidney tumors (T1-T2). Glomerular filtration rate data were assessed using single photon emission computed tomography (SPECT)/computed tomography imaging [using 9mTc-DTPA (diethylenetriaminepentaacetic acid) renal dynamic imaging]. The independent determinants of postoperative renal function or renal function change were determined using linear regression analysis. In addition, the patient's demographic, clinical, and nephrometry characteristics were collected.
    Results: A total of 58 patients were finally enrolled. The preoperative and postoperative GFR of bilateral kidneys showed a significant positive correlation. Postoperative GFR of the operated kidney was the independent predictor of GFR of contralateral kidney (p = 0.001). Tumor diameter (p = 0.036), age (p = 0.005), and postoperative GFR of the contralateral kidney (p = 0.001) were all independent predictors of postoperative GFR of the operated kidney. ΔGFR1 was the independent predictor of ΔGFR2. Results showed that a more pronounced postoperative decline in GFR on the operated side corresponded to a weaker compensatory capacity of the contralateral-side kidney.
    Conclusions: During the course of the surgical procedure, the active endeavor to safeguard the renal function of the operated kidney side holds paramount importance, which yields positive outcomes for postoperative kidney function on the contralateral side, consequently contributing to the overall preservation of renal function.
    MeSH term(s) Humans ; Carcinoma, Renal Cell/surgery ; Glomerular Filtration Rate ; Retrospective Studies ; Kidney/pathology ; Kidney Neoplasms/pathology ; Nephrectomy/adverse effects ; Nephrectomy/methods
    Language English
    Publishing date 2023-12-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 204048-7
    ISSN 1573-2584 ; 0301-1623 ; 0042-1162
    ISSN (online) 1573-2584
    ISSN 0301-1623 ; 0042-1162
    DOI 10.1007/s11255-023-03901-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: One-way acoustic beam splitting in spatial four-waveguide couplers designed by adiabatic passage

    Shuai Tang / Jin-Lei Wu / Cheng Lü / Jiabao Yao / Xiaosai Wang / Jie Song / Yongyuan Jiang

    New Journal of Physics, Vol 25, Iss 3, p

    2023  Volume 033032

    Abstract: In this work, we introduce quantum-mechanical adiabatic passage into the design of spatial acoustic four-waveguide (WG) couplers. Thanks to the agreement in form between the Schrödinger equation in quantum mechanics and the coupled-mode equation of ... ...

    Abstract In this work, we introduce quantum-mechanical adiabatic passage into the design of spatial acoustic four-waveguide (WG) couplers. Thanks to the agreement in form between the Schrödinger equation in quantum mechanics and the coupled-mode equation of classical wave, the behavior of propagating wave in coupled WGs is capable of mapping to quantum states driven by external fields. By coupling the input and output WGs with a mediator WG in space, an apparent beam splitting is realized and the ratio of intensity can be customized arbitrarily by altering the space-dependent coupling strengths. Moreover, a one-way propagation feature is exhibited in the spatial coupler when an appropriate loss is introduced in the mediator WG owing to the existence of dark state. This work builds a bridge between quantum adiabatic technology and acoustic beam splitter, which may have potential applications in acoustic communication, filtering and detection.
    Keywords acoustic waveguide coupler ; adiabatic passage ; beam splitting ; one-way propagation ; Science ; Q ; Physics ; QC1-999
    Subject code 535
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher IOP Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Alterations of ileal mucosa-associated microbiota in hypercholesterolemia patients

    Jia Li / Jinxia Ma / Weihua Wang / Haitao Du / Shuai Tang / Yi Li / Wenya Zhu / Ru Zhang / Jun Wan

    Heliyon, Vol 9, Iss 12, Pp e22116- (2023)

    2023  

    Abstract: Many metabolic diseases have been demonstrated to be associated with changes in the microbiome. However, no studies have yet been conducted to examine the characteristics of the mucosal microbiota of patients with hypercholesterolemia. We aimed to ... ...

    Abstract Many metabolic diseases have been demonstrated to be associated with changes in the microbiome. However, no studies have yet been conducted to examine the characteristics of the mucosal microbiota of patients with hypercholesterolemia. We aimed to examine mucosa-associated microbiota in subjects with hypercholesterolemia. We conducted a case-control study, in which ileal mucosal samples were collected from 13 hypercholesterolemia patients and 13 controls for 16S rRNA gene sequencing. There were differences in the composition of ileal mucosal microbiota based on beta diversity between the hypercholesterolemia and control groups (P < 0.05). Compared with the control group, the phylum Bacteroidetes and the genera Bacteroides, Butyricicoccus, Parasutterella, Candidatus_Soleaferrea, and norank_f__norank_o__Izemoplasmatales were less abundant in the hypercholesterolemia group (P < 0.05), while the genus Anaerovibrio was enriched in the hypercholesterolemia group (P < 0.05). The relative abundance of Bacteroides was negatively correlated with total cholesterol and low-density lipoprotein cholesterol (P < 0.01). The relative abundance of Coprococcus was negatively correlated with triglycerides and body mass index (all P < 0.05). PICRUSt functional prediction analysis showed that pathways related to Glycerophospholipid metabolism, ABC transporters, Phosphotransferase system, and Biofilm formation - Escherichia coli, and infectious diseases of pathogenic Escherichia coli were enriched in the hypercholesterolemia group. This work suggests a potential role of ileal mucosal microbiota in the development of hypercholesterolemia.
    Keywords Hypercholesterolemia ; Microbiota ; Mucosa ; Small intestine ; 16S rRNA gene sequencing ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 616
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: A single-operator technique in ultrasound-guided regional anesthesia

    Shuai Tang / Jin-Lei Li / Yu-Guan Zhang / Yu-Guang Huang / Xiu-Yuan Hao

    Chinese Medical Journal, Vol 134, Iss 6, Pp 734-

    2021  Volume 735

    Keywords Medicine ; R
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Wolters Kluwer
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: A Copper-Based Biosensor for Dual-Mode Glucose Detection

    Kai Li / Xiaoyu Xu / Wanshan Liu / Shouzhi Yang / Lin Huang / Shuai Tang / Ziyue Zhang / Yuning Wang / Fangmin Chen / Kun Qian

    Frontiers in Chemistry, Vol

    2022  Volume 10

    Abstract: Glucose is a source of energy for daily activities of the human body and is regarded as a clinical biomarker, due to the abnormal glucose level in the blood leading to many endocrine metabolic diseases. Thus, it is indispensable to develop simple, ... ...

    Abstract Glucose is a source of energy for daily activities of the human body and is regarded as a clinical biomarker, due to the abnormal glucose level in the blood leading to many endocrine metabolic diseases. Thus, it is indispensable to develop simple, accurate, and sensitive methods for glucose detection. However, the current methods mainly depend on natural enzymes, which are unstable, hard to prepare, and expensive, limiting the extensive applications in clinics. Herein, we propose a dual-mode Cu2O nanoparticles (NPs) based biosensor for glucose analysis based on colorimetric assay and laser desorption/ionization mass spectrometry (LDI MS). Cu2O NPs exhibited excellent peroxidase-like activity and served as a matrix for LDI MS analysis, achieving visual and accurate quantitative analysis of glucose in serum. Our proposed method possesses promising application values in clinical disease diagnostics and monitoring.
    Keywords Cu2O nanoparticle ; colorimetric ; mass spectrometry ; glucose ; biosensor ; Chemistry ; QD1-999
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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