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  1. Article ; Online: Effects of Low-Energy-Density Microwave Treatment on Graphene/Polyvinyl Alcohol-Modified Poplar Veneer

    Shuangshuang Wu / Wei Xu

    Forests, Vol 13, Iss 210, p

    2022  Volume 210

    Abstract: The combination of natural wood and graphene can provide a new type of material with excellent mechanical properties and thermal conductivity. However, it is difficult for graphene to uniformly penetrate the wood due to the anisotropy of natural wood and ...

    Abstract The combination of natural wood and graphene can provide a new type of material with excellent mechanical properties and thermal conductivity. However, it is difficult for graphene to uniformly penetrate the wood due to the anisotropy of natural wood and the agglomeration of graphene. In this work, poplar veneer was treated with low-energy-density microwave to expand the entry pathways for the graphene steering liquid. The porosity, weight percent gain, and chromatic aberration were used to examine the impact of the microwave time and power. We tested the mechanical properties, thermal conductivity of the graphene/polyvinyl alcohol-modified poplar veneer to evaluate its properties. At the same time, SEM, XRD, and FT-IR were used to characterize its physical and chemical structure. The results showed that low-energy-density microwave treatment increased the weight percentage gain (WPG) and porosity without affecting the mechanical properties of the poplar veneer. The graphene-modified poplar veneer with the optimal overall performance was obtained by microwave treatment at 100% microwave power for 50 s. Indeed, the micro-characterization also revealed that the microwave treatment mostly attacked the wood rays but had little effect on the materialized structure. Therefore, low-energy-density microwave treatment could be an energy-saving and efficient way to improve graphene-impregnated veneers.
    Keywords microwave treatment ; poplar veneer ; multilayer graphene ; impregnation effect ; Plant ecology ; QK900-989
    Subject code 690
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Effects of the Ball Milling Process on the Particle Size of Graphene Oxide and Its Application in Enhancing the Thermal Conductivity of Wood

    Na Zhang / Yiqun Mao / Shuangshuang Wu / Wei Xu

    Forests, Vol 13, Iss 8, p

    2022  Volume 1325

    Abstract: To improve the dispersion of graphene oxide particles in wood for better thermal conductivity, this paper proposes the feasibility of obtaining graphene oxide with a smaller particle size using ball milling and its application in melamine resin-modified ... ...

    Abstract To improve the dispersion of graphene oxide particles in wood for better thermal conductivity, this paper proposes the feasibility of obtaining graphene oxide with a smaller particle size using ball milling and its application in melamine resin-modified poplar veneer. The median diameter of multilayer graphene oxide was measured to learn the effects of different ball milling conditions on the particle size of graphene oxide, and the optimum ball milling process was chosen. In addition, the microscopic characterization of graphene oxide under the optimum ball milling process was carried out to investigate the microstructural changes in multilayer graphene after ball milling. Furthermore, the thermal conductivity of the graphene oxide/melamine resin-impregnated mixture modified veneer with the optimum ball milling process was also tested. The results show that, under the optimum ball milling process conditions of SDS wet ball milling with a vibration frequency of 30 Hz for 60 min, the particle size of the multilayer graphene was the smallest, and the median diameter could be reduced to 124 nm. Simultaneously, the thermal conductivity of the melamine resin-modified poplar veneer enhanced by the ball-milled graphene reached 0.405 W·m −1 ·K −1 . In addition, it revealed that the number of graphene oxide layers was reduced to four after ball milling. However, the multilayer graphene was partially oxidized, the lamellar structure was destroyed and the crystallinity was reduced.
    Keywords thermal conductivity ; ball milling ; multilayer graphene oxide ; particle size ; microscopic characterization ; Plant ecology ; QK900-989
    Subject code 620
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: The Removal Mechanism Considering the Shape and Size of Abrasive Particles in Wet Blast Cleaning of Paint

    Chenghao Li / Xiujie Jia / Shuangshuang Wu / Fangyi Li / Xing Wang / Yuan Ren

    Sustainability, Vol 14, Iss 14289, p

    2022  Volume 14289

    Abstract: Recently, wet blast cleaning of paint has attracted attention in remanufacturing processes, owing to its high efficiency and environmental friendliness. However, studies of removal mechanism have rarely considered the properties of abrasive particles; ... ...

    Abstract Recently, wet blast cleaning of paint has attracted attention in remanufacturing processes, owing to its high efficiency and environmental friendliness. However, studies of removal mechanism have rarely considered the properties of abrasive particles; thus, there is insufficient theoretical guidance on the process optimization, resulting in energy waste during the cleaning process. Therefore, the mechanism in wet blast cleaning of paint was researched in this study, which focused on the effects of abrasive particle shape and size on mechanism. The results indicate that the removal mechanisms of angular and spherical abrasive particles are significantly different, and that of angular abrasive particles is not affected by the particle size, whereas that of spherical abrasive particles is significantly affected. The main removal mechanism for all angular abrasive particles is brittle fracture caused by large impact stresses. For large spherical abrasive particles (≥60-mesh), the main mechanism is brittle fracture due to the intersection of longitudinal-through fatigue cracks and interface cracks, and for small spherical abrasive particles (≤80-mesh), it is brittle fracture due to fatigue cracks and impact cracks. This study provides good insight into abrasive particles and serves as a good basis for exploring the process parameters for wet blast cleaning.
    Keywords wet blast cleaning ; removal paint ; mechanism ; particle properties ; remanufacturing ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 660
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Output Feedback Distributed Containment Control for High-Order Nonlinear Multiagent Systems.

    Yafeng Li / Changchun Hua / Shuangshuang Wu / Xinping Guan

    IEEE transactions on cybernetics

    2017  Volume 47, Issue 8, Page(s) 2032–2043

    Abstract: In this paper, we study the problem of output feedback distributed containment control for a class of high-order nonlinear multiagent systems under a fixed undirected graph and a fixed directed graph, respectively. Only the output signals of the systems ... ...

    Abstract In this paper, we study the problem of output feedback distributed containment control for a class of high-order nonlinear multiagent systems under a fixed undirected graph and a fixed directed graph, respectively. Only the output signals of the systems can be measured. The novel reduced order dynamic gain observer is constructed to estimate the unmeasured state variables of the system with the less conservative condition on nonlinear terms than traditional Lipschitz one. Via the backstepping method, output feedback distributed nonlinear controllers for the followers are designed. By means of the novel first virtual controllers, we separate the estimated state variables of different agents from each other. Consequently, the designed controllers show independence on the estimated state variables of neighbors except outputs information, and the dynamics of each agent can be greatly different, which make the design method have a wider class of applications. Finally, a numerical simulation is presented to illustrate the effectiveness of the proposed method.
    Language English
    Publishing date 2017-01-31
    Publishing country United States
    Document type Journal Article
    ISSN 2168-2275
    ISSN (online) 2168-2275
    DOI 10.1109/TCYB.2017.2655054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Process Parameters Optimization of Wet Shot Peening for Paint Cleaning

    Shuangshuang Wu / Xiujie Jia / Sheng Xiong / Fangyi Li / Mingliang Ma / Xing Wang / Chenghao Li

    Sustainability, Vol 13, Iss 12915, p

    2021  Volume 12915

    Abstract: Wet shot peening (WSP) cleaning technology has the advantages of being green, having a high efficiency, and producing almost no pollution to the environment. Under the development trend of green environmental protection, WSP is more and more desired by ... ...

    Abstract Wet shot peening (WSP) cleaning technology has the advantages of being green, having a high efficiency, and producing almost no pollution to the environment. Under the development trend of green environmental protection, WSP is more and more desired by the public. However, in the study of WSP cleaning paint, there is little research on process parameter optimization. Accordingly, this article uses an orthogonal experiment, taking the cleaning efficiency and the substrate removal mass as objectives, to optimize the parameters of pressure, stand-off distance, traverse rate, and cleaning times. The experimental results show that the cleaning efficiency is improved by increasing the pressure, stand-off distance, and traverse rate or decreasing the cleaning times within the scope of this experiment. The pressure and cleaning times are positively correlated with the substrate removal mass, whereas the traverse rate is negatively correlated. As the stand-off distance increases, the substrate removal mass initially increases and then decreases. The traverse rate has a significant influence on the cleaning efficiency and the substrate removal mass. The optimal process parameters based on the cleaning efficiency are 0.45 MPa pressure, 140 mm stand-off distance, 5 mm/s traverse rate, and one-time cleaning. Besides, the cleaning efficiency at such conditions is 64.23 %/min. Additionally, the substrate removal mass is optimized under 0.25 MPa pressure, 60 mm (or 140 mm) stand-off distance, 5 mm/s traverse rate, and one-time cleaning to give a substrate removal mass of approximately zero. The analysis of parameters provides a reference for selecting the parameters in the actual application of WSP cleaning.
    Keywords wet shot peening cleaning ; parameter optimization ; cleaning efficiency ; ratio ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 660
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Threshold Definition for Monitoring Gapa Landslide under Large Variations in Reservoir Level Using GNSS

    Shuangshuang Wu / Xinli Hu / Wenbo Zheng / Matteo Berti / Zhitian Qiao / Wei Shen

    Remote Sensing, Vol 13, Iss 4977, p

    2021  Volume 4977

    Abstract: The triggering threshold is one of the most important parameters for landslide early warning systems (EWSs) at the slope scale. In the present work, a velocity threshold is recommended for an early warning system of the Gapa landslide in Southwest China, ...

    Abstract The triggering threshold is one of the most important parameters for landslide early warning systems (EWSs) at the slope scale. In the present work, a velocity threshold is recommended for an early warning system of the Gapa landslide in Southwest China, which was reactivated by the impoundment of a large reservoir behind Jinping’s first dam. Based on GNSS monitoring data over the last five years, the velocity threshold is defined by a novel method, which is implemented by the forward and reverse double moving average of time series. As the landslide deformation is strongly related to the fluctuations in reservoir water levels, a crucial water level is also defined to reduce false warnings from the velocity threshold alone. In recognition of the importance of geological evolution, the evolution process of the Gapa landslide from topping to sliding is described in this study to help to understand its behavior and predict its potential trends. Moreover, based on the improved Saito’s three-stage deformation model, the warning level is set as “attention level”, because the current deformation stage of the landslide is considered to be between the initial and constant stages. At present, the early warning system mainly consists of six surface displacement monitoring sites and one water level observation site. If the daily recorded velocity in each monitoring site exceeds 4 mm/d and, meanwhile, the water level is below 1820 m above sea level (asl), a warning of likely landslide deformation accelerations will be released by relevant monitoring sites. The thresholds are always discretely exceeded on about 3% of annual monitoring days, and they are most frequently exceeded in June (especially in mid-June). The thresholds provide an efficient and effective way for judging accelerations of this landslide and are verified by the current application. The work presented provides critical insights into the development of early warning systems for reservoir-induced large-scale landslides.
    Keywords threshold ; landslide ; early warning system ; velocity ; water level ; GNSS ; Science ; Q
    Subject code 550
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Parameter Optimization and Effect Analysis of Low-Pressure Abrasive Water Jet (LPAWJ) for Paint Removal of Remanufacturing Cleaning

    Sheng Xiong / Xiujie Jia / Shuangshuang Wu / Fangyi Li / Mingliang Ma / Xing Wang

    Sustainability, Vol 13, Iss 5, p

    2021  Volume 2900

    Abstract: As an environmentally friendly method, water jet (WJ) technology plays a significant role in the field of remanufacturing cleaning. The cleaning capacity of a WJ is severely restricted by the water pressure, while the impact force will be too large and ... ...

    Abstract As an environmentally friendly method, water jet (WJ) technology plays a significant role in the field of remanufacturing cleaning. The cleaning capacity of a WJ is severely restricted by the water pressure, while the impact force will be too large and may damage the cleaned substrate as well as cause energy waste if the pressure is too high. However, by adding abrasives, the cleaning capacity of a low-pressure water jet (LPWJ) will be considerably improved. Although abrasive water jet (AWJ) technology has been used in mechanical machining for decades, very limited research work can be found in the literature for remanufacturing cleaning. In this paper, the role of abrasives in low-pressure abrasive water jet (LPAWJ) cleaning was described. Cleaning performance with different parameters (abrasive feed rate condition, water pressure and standoff distance) in paint removal was experimentally investigated by using the Taguchi design of experiment. The experimental results indicated that the water pressure was the most dominant factor and the optimal parameter combination was the second feed rate condition, 9 MPa water pressure and 300 mm standoff distance. The influence law between the cleaning performance and various factors was explored, which can provide remanufacturers with directions in selection of the optimal parameters in the LPAWJ cleaning process. By designing contrast experiments, the results showed that the cleaning capacity of an LPAWJ is better than that of a pure LPWJ and the residual effect in terms of changes in surface roughness, residual stress and morphology is a little larger.
    Keywords low-pressure abrasive water jet (LPAWJ) cleaning ; remanufacturing ; paint removal ; Taguchi method ; cleaning rate ; surface roughness ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 660
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Paradoxical effects of posterior intralaminar thalamic calretinin neurons on hippocampal seizure via distinct downstream circuits

    Yingbei Qi / Heming Cheng / Qiuwen Lou / Xia Wang / Nanxi Lai / Chenshu Gao / Shuangshuang Wu / Cenglin Xu / Yeping Ruan / Zhong Chen / Yi Wang

    iScience, Vol 25, Iss 5, Pp 104218- (2022)

    2022  

    Abstract: Summary: Epilepsy is a circuit-level brain disorder characterized by hyperexcitatory seizures with unclear mechanisms. Here, we investigated the causal roles of calretinin (CR) neurons in the posterior intralaminar thalamic nucleus (PIL) in hippocampal ... ...

    Abstract Summary: Epilepsy is a circuit-level brain disorder characterized by hyperexcitatory seizures with unclear mechanisms. Here, we investigated the causal roles of calretinin (CR) neurons in the posterior intralaminar thalamic nucleus (PIL) in hippocampal seizures. Using c-fos mapping and calcium fiber photometry, we found that PIL CR neurons were activated during hippocampal seizures in a kindling model. Optogenetic activation of PIL CR neurons accelerated seizure development, whereas inhibition retarded seizure development. Further, viral-based circuit tracing verified that PIL CR neurons were long-range glutamatergic neurons, projecting toward various downstream regions. Interestingly, selective inhibition of PIL-lateral amygdala CR circuit attenuated seizure progression, whereas inhibition of PIL-zona incerta CR circuit presented an opposite effect. These results indicated that CR neurons in the PIL play separate roles in hippocampal seizures via distinct downstream circuits, which complements the pathogenic mechanisms of epilepsy and provides new insight for the precise medicine of epilepsy.
    Keywords Biological sciences ; Molecular neuroscience ; Cellular neuroscience ; Science ; Q
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Peripheral blood circular RNA hsa_circ_0058493 as a potential novel biomarker for silicosis and idiopathic pulmonary fibrosis

    Zhounan Cheng / Yingyi Zhang / Shuangshuang Wu / Rui Zhao / Yuhui Yu / Yan Zhou / Zhen Zhou / Yang Dong / Anni Qiu / Huiwen Xu / Yiran Liu / Wendi Zhang / Tian Tian / Qiuyun Wu / Hongyan Gu / Minjie Chu

    Ecotoxicology and Environmental Safety, Vol 236, Iss , Pp 113451- (2022)

    2022  

    Abstract: Existing studies reported that some circular RNAs (circRNAs) play vital roles in the development of pulmonary fibrosis. However, few studies explored the biomarker potential of circRNAs for pulmonary fibrosis based on population data. Therefore, we aimed ...

    Abstract Existing studies reported that some circular RNAs (circRNAs) play vital roles in the development of pulmonary fibrosis. However, few studies explored the biomarker potential of circRNAs for pulmonary fibrosis based on population data. Therefore, we aimed to identify peripheral blood circRNAs as potential biomarkers for diagnosing silicosis and idiopathic pulmonary fibrosis (IPF). In brief, an RNA-seq screening based on 4 silicosis cases and 4 controls was initially performed. Differentially expressed circRNAs were combined with the human serum circRNA dataset to identify overlapping serum-detectable circRNAs, followed by validation using the GEO dataset (3 IPF cases and 3 controls) and subsequent qRT-PCR, including 84 additional individuals. Following the above steps, 243 differentially expressed circRNAs were identified during the screening stage, with fold changes ≥ 1.5 and P < 0.05. Of note, the human serum circRNA dataset encompassed 28 of 243 circRNAs. GEO (GSE102660) validation revealed two highly expressed circRNAs (P < 0.05) in the IPF case group. Furthermore, at the enlarged sample validation stage, hsa_circ_0058493 was highly expressed in both silicosis and IPF cases (silicosis: P = 1.16 × 10−6; IPF: P = 7.46 × 10−5). Additionally, hsa_circ_0058493 expression was significantly increased in MRC-5 cells upon TGF-β1 treatment, while hsa_circ_0058493 knockdown inhibited the expression of fibrotic molecules by affecting the epithelial-mesenchymal transition process. These shreds of evidence indicated that hsa_circ_0058493 might serve as a novel biomarker for diagnosing silicosis and IPF.
    Keywords RNA-seq ; Circular RNA ; Hsa_circ_0058493 ; Pulmonary fibrosis ; Biomarker ; Environmental pollution ; TD172-193.5 ; Environmental sciences ; GE1-350
    Subject code 610
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Inhibition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models of FLT3 -Mutated Acute Myeloid Leukemia

    Shuangshuang Wu / Holly Edwards / Deying Wang / Shuang Liu / Xinan Qiao / Jenna Carter / Yue Wang / Jeffrey W. Taub / Guan Wang / Yubin Ge

    Cells, Vol 11, Iss 2752, p

    2022  Volume 2752

    Abstract: FMS-like tyrosine kinase 3 ( FLT3 )-internal tandem duplication ( FLT3 -ITD) mutations occur in about 25% of all acute myeloid leukemia (AML) patients and confer a poor prognosis. FLT3 inhibitors have been developed to treat patients with FLT3 -mutated ... ...

    Abstract FMS-like tyrosine kinase 3 ( FLT3 )-internal tandem duplication ( FLT3 -ITD) mutations occur in about 25% of all acute myeloid leukemia (AML) patients and confer a poor prognosis. FLT3 inhibitors have been developed to treat patients with FLT3 -mutated AML and have shown promise, though the acquisition of resistance occurs, highlighting the need for combination therapies to prolong the response to FLT3 inhibitors. In this study, we investigated the selective Mcl-1 inhibitor AZD5991 in combination with the FLT3 inhibitors gilteritinib and MRX-2843. The combinations synergistically induce apoptosis in AML cell lines and primary patient samples. The FLT3 inhibitors downregulate c-Myc transcripts through the suppression of the MEK/ERK and JAK2/STAT5 pathways, resulting in the decrease in c-Myc protein. This suppression of c-Myc plays an important role in the antileukemic activity of AZD5991. Interestingly, the suppression of c-Myc enhances AZD5991-inudced cytochrome c release and the subsequent induction of apoptosis. AZD5991 enhances the antileukemic activity of the FLT3 inhibitors gilteritinib and MRX-2843 against FLT3 -mutated AML in vitro, warranting further development.
    Keywords acute myeloid leukemia ; Mcl-1 ; AZD5991 ; FLT3 ; FLT3-ITD ; MRX-2843 ; Biology (General) ; QH301-705.5
    Subject code 500
    Language English
    Publishing date 2022-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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