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  1. Book ; Online ; E-Book: Applied microbiology and bioengineering

    Shukla, Pratyoosh

    an interdisciplinary approach

    2019  

    Author's details edited by Pratyoosh Shukla
    Language English
    Size 1 Online-Ressource (xxvii, 251 Seiten), Illustrationen
    Publisher Academic Press
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019867023
    ISBN 978-0-12-815548-6 ; 9780128154076 ; 0-12-815548-5 ; 0128154071
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  2. Book ; Online ; E-Book: Recent advances in applied microbiology

    Shukla, Pratyoosh

    2017  

    Author's details Pratyoosh Shukla, editor
    Keywords Medicine ; Medical microbiology ; Biomedical engineering ; Microbiology ; Bacteriology
    Subject code 610.28
    Language English
    Size 1 Online-Ressource (xiii, 290 Seiten), Illustrationen
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019536509
    ISBN 978-981-10-5275-0 ; 9789811052743 ; 981-10-5275-1 ; 9811052743
    DOI 10.1007/978-981-10-5275-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Engineering regulatory networks of cyanobacteria.

    Bongirwar, Riya / Shukla, Pratyoosh

    Trends in biotechnology

    2024  

    Abstract: Engineering a cell's regulatory networks to dynamically control gene expression has been considered a new frontier in biological engineering. In cyanobacteria, the lack of well-characterized, modular gene regulatory elements makes regulatory network ... ...

    Abstract Engineering a cell's regulatory networks to dynamically control gene expression has been considered a new frontier in biological engineering. In cyanobacteria, the lack of well-characterized, modular gene regulatory elements makes regulatory network engineering challenging. Here, we suggest potential tools to modify various gene expression steps in cyanobacterial regulatory networks.
    Language English
    Publishing date 2024-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 47474-5
    ISSN 1879-3096 ; 0167-7799
    ISSN (online) 1879-3096
    ISSN 0167-7799
    DOI 10.1016/j.tibtech.2023.12.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2750: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Microalgal multiomics-based approaches in bioremediation of hazardous contaminants.

    Kumar, Niwas / Shukla, Pratyoosh

    Environmental research

    2024  Volume 247, Page(s) 118135

    Abstract: The enhanced industrial growth and higher living standards owing to the incessant population growth have caused heightened production of various chemicals in different manufacturing sectors globally, resulting in pollution of aquatic systems and soil ... ...

    Abstract The enhanced industrial growth and higher living standards owing to the incessant population growth have caused heightened production of various chemicals in different manufacturing sectors globally, resulting in pollution of aquatic systems and soil with hazardous chemical contaminants. The bioremediation of such hazardous pollutants through microalgal processes is a viable and sustainable approach. Accomplishing microalgal-based bioremediation of polluted wastewater requires a comprehensive understanding of microalgal metabolic and physiological dynamics. Microalgae-bacterial consortia have emerged as a sustainable agent for synergistic bioremediation and metabolite production. Effective bioremediation involves proper consortium functioning and dynamics. The present review highlights the mechanistic processes employed through microalgae in reducing contaminants present in wastewater. It discusses the multi-omics approaches and their advantages in understanding the biological processes, monitoring, and dynamics among the partners in consortium through metagenomics. Transcriptomics, proteomics, and metabolomics enable an understanding of microalgal cell response toward the contaminants in the wastewater. Finally, the challenges and future research endeavors are summarised to provide an outlook on microalgae-based bioremediation.
    MeSH term(s) Wastewater ; Microalgae ; Biodegradation, Environmental ; Multiomics ; Proteomics ; Biomass
    Chemical Substances Wastewater
    Language English
    Publishing date 2024-01-12
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2024.118135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 726: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Microalgal-based bioremediation of emerging contaminants: Mechanisms and challenges.

    Kumar, Niwas / Shukla, Pratyoosh

    Environmental pollution (Barking, Essex : 1987)

    2023  Volume 337, Page(s) 122591

    Abstract: Emerging contaminants (ECs) in different ecosystems have consistently been acknowledged as a global issue due to toxicity, human health implications, and potential role in generating and disseminating antimicrobial resistance. The existing wastewater ... ...

    Abstract Emerging contaminants (ECs) in different ecosystems have consistently been acknowledged as a global issue due to toxicity, human health implications, and potential role in generating and disseminating antimicrobial resistance. The existing wastewater treatment system is incompetent at eliminating ECs since the effluent water contains significant concentrations of ECs, viz., antibiotics (0.03-13.0 μg L
    MeSH term(s) Humans ; Microalgae/metabolism ; Biodegradation, Environmental ; Ecosystem ; Prospective Studies ; Wastewater ; Biomass ; Biofuels
    Chemical Substances Wastewater ; Biofuels
    Language English
    Publishing date 2023-09-20
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2023.122591
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2599: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Analysis of endoglucanases production using metatranscriptomics and proteomics approach.

    Dixit, Mandeep / Shukla, Pratyoosh

    Advances in protein chemistry and structural biology

    2023  Volume 138, Page(s) 211–231

    Abstract: The cellulases are among the most used enzyme in industries for various purposes. They add up to the green economy perspective and cost-effective production of enterprises. Biorefineries, paper industries, and textile industries are foremost in their ... ...

    Abstract The cellulases are among the most used enzyme in industries for various purposes. They add up to the green economy perspective and cost-effective production of enterprises. Biorefineries, paper industries, and textile industries are foremost in their usage. The production of endoglucanases from microorganisms is a valuable resource and can be exploited with the help of biotechnology. The present review provides some insight into the uses of endoglucanases in different industries and the potent fungal source of these enzymes. The advances in the enzyme technology has helped towards understanding some pathways to increase the production of industrial enzymes from microorganisms. The proteomics analysis and systems biology tools also help to identify these pathways for the enhanced production of such enzymes. This review deciphers the use of proteomics tools to analyze the potent microorganisms and identify suitable culture conditions to increase the output of endoglucanases. The review also includes the role of quantitative proteomics which is a powerful technique to get results faster and more timely. The role of metatranscriptomic approaches are also described which are helpful in the enzyme engineering for their efficient use under industrial conditions. Conclusively, this review helps to understand the challenges faced in the industrial use of endoglucanases and their further improvement.
    MeSH term(s) Cellulase/metabolism ; Proteomics ; Cellulases/metabolism ; Biotechnology
    Chemical Substances Cellulase (EC 3.2.1.4) ; Cellulases (EC 3.2.1.-)
    Language English
    Publishing date 2023-06-14
    Publishing country Netherlands
    Document type Review ; Journal Article
    ZDB-ID 2473077-4
    ISSN 1876-1631 ; 1876-1623
    ISSN (online) 1876-1631
    ISSN 1876-1623
    DOI 10.1016/bs.apcsb.2023.04.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Metabolic sink engineering in cyanobacteria: Perspectives and applications.

    Bongirwar, Riya / Shukla, Pratyoosh

    Bioresource technology

    2023  Volume 379, Page(s) 128974

    Abstract: Recent advances in metabolic engineering have made cyanobacteria emerge as promising and attractive microorganisms for sustainable production, by exploiting their natural capability for producing metabolites. The potential of metabolically engineered ... ...

    Abstract Recent advances in metabolic engineering have made cyanobacteria emerge as promising and attractive microorganisms for sustainable production, by exploiting their natural capability for producing metabolites. The potential of metabolically engineered cyanobacterium would depend on its source-sink balance in the same way as other phototrophs. In cyanobacteria, the amount of light energy harvested (Source) is incompletely utilized by the cell to fix carbon (sink) resulting in wastage of the absorbed energy causing photoinhibition and cellular damage leading to lowered photosynthetic efficiency. Although regulatory pathways like photo-acclimation and photoprotective processes can be helpful unfortunately they limit the cell's metabolic capacity. This review describes approaches for source-sink balance and engineering heterologous metabolic sinks in cyanobacteria for enhanced photosynthetic efficiency. The advances for engineering additional metabolic pathways in cyanobacteria are also described which will provide a better understanding of the cyanobacterial source-sink balance and approaches for efficient cyanobacterial strains for valuable metabolites.
    MeSH term(s) Metabolic Engineering/methods ; Cyanobacteria/genetics ; Cyanobacteria/metabolism ; Photosynthesis ; Metabolic Networks and Pathways
    Language English
    Publishing date 2023-03-27
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1065195-0
    ISSN 1873-2976 ; 0960-8524
    ISSN (online) 1873-2976
    ISSN 0960-8524
    DOI 10.1016/j.biortech.2023.128974
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 3258: Show issues

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  8. Article: Synthetic Biology Perspectives of Microbial Enzymes and Their Innovative Applications.

    Shukla, Pratyoosh

    Indian journal of microbiology

    2019  Volume 59, Issue 4, Page(s) 401–409

    Abstract: Microbial enzymes are high in demand and there is focus on their efficient, cost effective and eco-friendly production. The relevant microbial enzymes for respective industries needs to be identified but the conventional technologies don't have much edge ...

    Abstract Microbial enzymes are high in demand and there is focus on their efficient, cost effective and eco-friendly production. The relevant microbial enzymes for respective industries needs to be identified but the conventional technologies don't have much edge over it. So, there is more attention towards high throughput methods for production of efficient enzymes. The enzymes produced by microbes need to be modified to bear the extreme conditions of the industries in order to get prolific outcomes and here the synthetic biology tools may be augmented to modify such microbes and enzymes. These tools are applied to synthesize novel and efficient enzymes. Use of computational tools for enzyme modification has provided new avenues for faster and specific modification of enzymes in a shorter time period. This review focuses on few important enzymes and their modification through synthetic biology tools including genetic modification, nanotechnology, post translational modification.
    Language English
    Publishing date 2019-08-23
    Publishing country India
    Document type Journal Article
    ZDB-ID 413422-9
    ISSN 0973-7715 ; 0046-8991
    ISSN (online) 0973-7715
    ISSN 0046-8991
    DOI 10.1007/s12088-019-00819-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2617: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: Microbiome engineering for bioremediation of emerging pollutants

    Singha, L. Paikhomba / Shukla, Pratyoosh

    Bioprocess Biosyst Eng. 2023 Mar., v. 46, no. 3 p.323-339

    2023  

    Abstract: Axenic microbial applications in the open environment are unrealistic and may not be always practically viable. Therefore, it is important to use mixed microbial cultures and their interactions with the microbiome in the targeted ecosystem to perform ... ...

    Abstract Axenic microbial applications in the open environment are unrealistic and may not be always practically viable. Therefore, it is important to use mixed microbial cultures and their interactions with the microbiome in the targeted ecosystem to perform robust functions towards their sustainability in harsh environmental conditions. Emerging pollutants like phthalates and hydrocarbons that are toxic to several aquatic and terrestrial life forms in the water bodies and lands are an alarming situation. The present review explores the possibility of devising an inclusive eco-friendly strategy like microbiome engineering which proves to be a unique and crucial technology involving the power of microbial communication through quorum sensing. This review discusses the interspecies and intra-species communications between different microbial groups with their respective environments. Moreover, this review also envisages the efforts for designing the next level of microbiome-host engineering concept (MHEC). The focus of the review also extended toward using omics and metabolic network analysis-based tools for effective microbiome engineering. These approaches might be quite helpful in the future to understand such microbial interactions but it will be challenging to implement in the real environment to get the desired functions. Finally, the review also discusses multiple approaches for the bioremediation of toxic chemicals from the soil environment.
    Keywords biochemical pathways ; bioprocessing ; bioremediation ; ecosystems ; edaphic factors ; microbiome ; phthalates ; toxicity
    Language English
    Dates of publication 2023-03
    Size p. 323-339.
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    Note Review
    ZDB-ID 1476357-6
    ISSN 1432-0797 ; 1615-7605 ; 1615-7591
    ISSN (online) 1432-0797 ; 1615-7605
    ISSN 1615-7591
    DOI 10.1007/s00449-022-02777-x
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Metabolic sink engineering in cyanobacteria: Perspectives and applications

    Bongirwar, Riya / Shukla, Pratyoosh

    Bioresource Technology. 2023 July, v. 379 p.128974-

    2023  

    Abstract: Recent advances in metabolic engineering have made cyanobacteria emerge as promising and attractive microorganisms for sustainable production, by exploiting their natural capability for producing metabolites. The potential of metabolically engineered ... ...

    Abstract Recent advances in metabolic engineering have made cyanobacteria emerge as promising and attractive microorganisms for sustainable production, by exploiting their natural capability for producing metabolites. The potential of metabolically engineered cyanobacterium would depend on its source-sink balance in the same way as other phototrophs. In cyanobacteria, the amount of light energy harvested (Source) is incompletely utilized by the cell to fix carbon (sink) resulting in wastage of the absorbed energy causing photoinhibition and cellular damage leading to lowered photosynthetic efficiency. Although regulatory pathways like photo-acclimation and photoprotective processes can be helpful unfortunately they limit the cell's metabolic capacity. This review describes approaches for source-sink balance and engineering heterologous metabolic sinks in cyanobacteria for enhanced photosynthetic efficiency. The advances for engineering additional metabolic pathways in cyanobacteria are also described which will provide a better understanding of the cyanobacterial source-sink balance and approaches for efficient cyanobacterial strains for valuable metabolites.
    Keywords Cyanobacteria ; autotrophs ; biochemical pathways ; carbon ; energy ; metabolic engineering ; metabolites ; photoinhibition ; radiation resistance ; technology ; Source-sink balance ; Photosynthetic efficiency ; Sink engineering ; Photoprotective pathways
    Language English
    Dates of publication 2023-07
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 1065195-0
    ISSN 1873-2976 ; 0960-8524
    ISSN (online) 1873-2976
    ISSN 0960-8524
    DOI 10.1016/j.biortech.2023.128974
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

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