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  1. Article: [A multi-channel input convolutional neural network for artifact reduction in quantitative susceptibility mapping].

    Si, W / Feng, Y

    Nan fang yi ke da xue xue bao = Journal of Southern Medical University

    2023  Volume 42, Issue 12, Page(s) 1799–1806

    Abstract: Objective: To develop a deep learning-based QSM reconstruction method for reducing artifacts to improve the accuracy of magnetic susceptibility results.: Methods: To eliminate artifacts caused by susceptibility interfaces with gigantic differences, ... ...

    Abstract Objective: To develop a deep learning-based QSM reconstruction method for reducing artifacts to improve the accuracy of magnetic susceptibility results.
    Methods: To eliminate artifacts caused by susceptibility interfaces with gigantic differences, we propose a multi-channel input convolutional neural network for artifact reduction (MAR-CNN) for solving the dipole inversion problem in QSM. In this neural network, the original tissue field was first separated into two components, which were subsequently imported as additional channels into a multi-channel 3D U-Net. MAR-CNN was compared with 3 conventional model-based methods, namely truncated k-space deconvolution (TKD), morphology enabled dipole inversion (MEDI), and improved sparse linear equation and least squares method (iLSQR), and with a deep learning method (QSMnet). High-frequency error norm, peak signal-to-noise ratio, normalized root mean squared error, and structure similarity index were reported for quantitative comparisons.
    Results: Experiments on healthy volunteers demonstrated that the results obtained using MAR-CNN had superior peak signal-to-noise ratio (43.12±1.19) and normalized root mean squared error (51.98± 3.65) to those of TKD, MEDI, iLSQR and QSMnet. MAR-CNN outperformed QSMnet reconstruction on all the 4 quantitative metrics with significant differences (
    Conclusion: The proposed MAR-CNN for artifact reduction is capable of improving the accuracy of deep learning- based QSM reconstruction to effectively reduce artifacts.
    MeSH term(s) Humans ; Artifacts ; Image Processing, Computer-Assisted/methods ; Neural Networks, Computer ; Signal-To-Noise Ratio ; Algorithms ; Magnetic Resonance Imaging
    Language Chinese
    Publishing date 2023-01-18
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2250951-3
    ISSN 1673-4254
    ISSN 1673-4254
    DOI 10.12122/j.issn.1673-4254.2022.12.07
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Fundamentals of Statistics and Clinical Research in Homeopathy by Lex Rutten and Martine Rutten

    Si, Weichen

    Homœopathic Links

    2023  Volume 36, Issue 03, Page(s) 248–250

    Language English
    Publishing date 2023-08-23
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 1199312-1
    ISSN 1860-3149 ; 1019-2050
    ISSN (online) 1860-3149
    ISSN 1019-2050
    DOI 10.1055/s-0043-1772611
    Database Thieme publisher's database

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  3. Article ; Online: Public health insurance and the labor market: Evidence from China's Urban Resident Basic Medical Insurance.

    Si, Wei

    Health economics

    2020  Volume 30, Issue 2, Page(s) 403–431

    Abstract: This study provides empirical evidence on the labor market effects of public health insurance using evidence from China. In 2007, China launched a national public health insurance program, Urban Resident Basic Medical Insurance (URBMI), targeting ... ...

    Abstract This study provides empirical evidence on the labor market effects of public health insurance using evidence from China. In 2007, China launched a national public health insurance program, Urban Resident Basic Medical Insurance (URBMI), targeting residents in urban areas who were not insured by employment-based health insurance. Using panel data from the China Health and Nutrition Survey, I identify the impacts of the program based on its staggered implementation across cities. I find that URBMI did not have a significant average causal effect on labor force participation. However, it did increase employment mobility, as evidenced by the decrease in long-term employment and expansion of fixed-term contract jobs and self-employment. After the program was implemented, job lock declined and job flexibility increased, especially among women, the less educated, and individuals with good health status. The results also suggest increased employment for unhealthy workers, indicating a direct health improvement effect.
    MeSH term(s) China ; Employment ; Female ; Health Status ; Humans ; Insurance, Health ; Urban Population
    Language English
    Publishing date 2020-11-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1135838-5
    ISSN 1099-1050 ; 1057-9230
    ISSN (online) 1099-1050
    ISSN 1057-9230
    DOI 10.1002/hec.4198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Judicial and legislative practice and related suggestions on off-label drug use in China.

    Si, Wenjie / Ma, Panpan

    BMC health services research

    2023  Volume 23, Issue 1, Page(s) 312

    Abstract: Background: Off-label drug use exists widely in medical practice and is also an area which easily triggers controversy between patients and medical institutions. Previous studies have identified the reasons why off-label drug use long exists. However, ... ...

    Abstract Background: Off-label drug use exists widely in medical practice and is also an area which easily triggers controversy between patients and medical institutions. Previous studies have identified the reasons why off-label drug use long exists. However, there is no multidimensional analysis on real judicial precedents about off-label drug use. This study aimed to investigate the dispute points on off-label drug use based on real cases in China, and proposed suggestions based on newly-leased Physicians Law.
    Methods: Our study is a retrospective study with all the 35 judicial precedents on off-label drug use extracted from China Judgments Online from 2014 to 2019. This study mainly used the methods of statistical analysis, inferential analysis, exemplification, literature summarization and comparative analysis.
    Results: According to the analysis of the 35 precedents of jurisdictions from 11 different aspects, it can be seen that the second-instance and retrial rates of this kind of cases are high, and the disputes between patients and medical institutions are fierce. In judicial practice of off-label drug use, medical institutions are determined whether to bear civil liability according to the constituent elements of medical tort liability: the rate of medical institutions' bearing liability for off-label drug use is not high, and medical institutions are not directly identified as infringing acts and they don't bear tort liability. The clear provisions about off-label drug use in Law of the People's Republic of China on Physicians which was implemented in March 2022 confirm this at the legislative level.
    Conclusions: By analyzing the current judicial practice of China's off-label drug use cases, and summarizing the dispute points between medical institution and patients, the constituent elements of tort liability, and the rules of evidence etc., suggestions are proposed to further regulate off-label drug use and promote safe and rational drug use.
    MeSH term(s) Humans ; China ; Liability, Legal ; Off-Label Use ; Retrospective Studies
    Language English
    Publishing date 2023-03-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050434-2
    ISSN 1472-6963 ; 1472-6963
    ISSN (online) 1472-6963
    ISSN 1472-6963
    DOI 10.1186/s12913-023-09293-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: What insights can be gained from optimizing the relevant research on methotrexate monotherapy versus methotrexate and apremilast combination therapy in the treatment of palmoplantar psoriasis?

    Si, Weichen / Wang, Zihan

    Indian journal of dermatology, venereology and leprology

    2023  , Page(s) 1–2

    Language English
    Publishing date 2023-10-17
    Publishing country United States
    Document type Letter
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.25259/IJDVL_337_2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Driving Mechanism of Urban Land Expansion from 2005 to 2018: The Case of Yangzhou, China.

    Meng, Lin / Si, Wentao

    International journal of environmental research and public health

    2022  Volume 19, Issue 23

    Abstract: The driving mechanism of expansion is the basis for policymaking in urban land management and control. In this study, Yangzhou city in China was used as an example. Based on the supply and demand theory of land, a framework was constructed to analyze the ...

    Abstract The driving mechanism of expansion is the basis for policymaking in urban land management and control. In this study, Yangzhou city in China was used as an example. Based on the supply and demand theory of land, a framework was constructed to analyze the driving factors behind urban land expansion. Path analysis was used to determine the direct and indirect factors driving urban land expansion. The results showed the following: (1) Urban land in Yangzhou city expanded 32,831.10 hm
    Language English
    Publishing date 2022-11-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph192315821
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Pro-Environmental Behavior: Examining the Role of Ecological Value Cognition, Environmental Attitude, and Place Attachment among Rural Farmers in China.

    Meng, Lin / Si, Wentao

    International journal of environmental research and public health

    2022  Volume 19, Issue 24

    Abstract: Studies on the factors that influence farmers' pro-environmental behavior could promote environmental management in rural areas. Jinan of China was selected as the case study area in this study. A structural equation model and multiple hierarchical ... ...

    Abstract Studies on the factors that influence farmers' pro-environmental behavior could promote environmental management in rural areas. Jinan of China was selected as the case study area in this study. A structural equation model and multiple hierarchical regression analysis were applied to analyze the influence mechanism of ecological value cognition on pro-environmental behavior. Environmental attitudes were set as the mediating variable and place attachment was selected as the moderating variable. The results showed that (1) ecological value cognition exhibited a positive influence on pro-environmental behavior in both direct and indirect ways. The indirect influence was mediated by environmental attitude. (2) Place identity and place dependence showed a positive direct influence on pro-environmental behavior. (3) It is suggested that in order to improve pro-environmental behavior, enhancing ecological value cognition, cultivating farmers' positive environmental attitude, increasing farmers' place attachment, and releasing reward and punishment measures are good strategies. The findings in this study are important to the improvement of the rural ecological environment and the quality of life of farmers. Meanwhile, the findings shed light on the construction process of ecological civilization and the improvement of public welfare.
    Language English
    Publishing date 2022-12-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph192417011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Enhancing the lifespan and durability of superamphiphobic surfaces for potential industrial applications: A review.

    Si, Wen / Guo, Zhiguang

    Advances in colloid and interface science

    2022  Volume 310, Page(s) 102797

    Abstract: A superamphiphobic surface is a special wettability surface that repels liquids with lower surface tension than water. Superamphiphobic surface has a variety of applications, such as: self-cleaning, anticorrosion, electrical conductivity, flame retardant, ...

    Abstract A superamphiphobic surface is a special wettability surface that repels liquids with lower surface tension than water. Superamphiphobic surface has a variety of applications, such as: self-cleaning, anticorrosion, electrical conductivity, flame retardant, flexible sensors, super-fast bubble bursting, droplet control. With the improvement of the theory of wettability, the superamphiphobic surface has developed rapidly recently. However, due to the problems of poor durability and short service life, the field of superamphiphobic has not been well promoted and applied in real life. These questions are also concerned by many researchers, and many related studies have been published in recent years. However, these studies lack logic and organization, and fail to obtain systematic induction and summary, which is not conducive to the follow-up research of subsequent researchers. Therefore, the main purpose of this review is to summarize and review the development, basic principles, preparation methods, durability characterization methods and applications of superamphiphobic surfaces, and the efforts made by researchers in recent years to enhance the durability of superamphiphobic surfaces. The main directions of durability enhancement are: structures, surface chemistry conditioning, adhesive, and versatile coating.
    MeSH term(s) Surface Properties ; Longevity ; Wettability ; Surface Tension ; Water/chemistry
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2022-10-18
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 210507-x
    ISSN 1873-3727 ; 0001-8686
    ISSN (online) 1873-3727
    ISSN 0001-8686
    DOI 10.1016/j.cis.2022.102797
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Bubble Unidirectional Transportation on Multipath Aerophilic Surfaces by Adjusting the Surface Microstructure.

    Dai, Xin / Si, Wen / Liu, Yifan / Zhang, Wenhao / Guo, Zhiguang

    ACS applied materials & interfaces

    2024  Volume 16, Issue 9, Page(s) 11984–11996

    Abstract: Comprehending and controlling the behavior of bubbles on solid surfaces is of significant importance in various fields including catalysis and drag reduction, both industrially and scientifically. Herein, Inspired by the superaerophilic properties of the ...

    Abstract Comprehending and controlling the behavior of bubbles on solid surfaces is of significant importance in various fields including catalysis and drag reduction, both industrially and scientifically. Herein, Inspired by the superaerophilic properties of the lotus leaf surface, a series of asymmetrically patterned aerophilic surfaces were prepared by utilizing a facile mask-spraying method for directional transport of underwater bubbles. The ability of bubbles to undergo self-driven transportation in an asymmetric pattern is attributed to the natural tendency of bubbles to move toward regions with lower surface energy. In this work, the microstructure of the aerophilic surface is demonstrated as a critical element that influences the self-driven transport of bubbles toward regions of lower surface energy. The microstructure characteristic affects the energy barrier of forming a continuous gas film on the final regions. We classify three distinct bubble behaviors on the aerophilic surface, which align with three different underwater gas film evolution states: Model I, Model II, and Model III. Furthermore, utilizing the energy difference between the energy barrier that forms a continuous gas film and the gas-gas merging, gas-liquid microreaction in a specific destination on the multiple paths can be easily realized by preinjecting a bubble in the final region. This work provides a new view of the microevolutionary process for the diffusion, transport, and merging behavior of bubbles upon contact with an aerophilic pattern surface.
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c15880
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Tumor Necrosis Factor α-Induced Protein 8-Like Protein 1 Binds to Protein Arginine Methyltransferase 1 To Suppress the Methylation of Signal Transducer and Activator of Transcription 3 and Cell Growth in Oral Squamous Cell Carcinoma.

    Liu, Bing / Si, Wen / Wei, Bo / Zhang, Xuan / Chen, Peng

    The American journal of pathology

    2024  

    Abstract: The tumor necrosis factor α-induced protein 8 (TIPE, also TNFAIP8 or OXi-α) family is a newly discovered series of proteins involved in immune regulation and tumorigenesis. TIPE1, a member of the TIPE/TNFAIP8/OXi-α family, has emerged as an anticancer- ... ...

    Abstract The tumor necrosis factor α-induced protein 8 (TIPE, also TNFAIP8 or OXi-α) family is a newly discovered series of proteins involved in immune regulation and tumorigenesis. TIPE1, a member of the TIPE/TNFAIP8/OXi-α family, has emerged as an anticancer-drug target, as it is promotes cancer cell apoptosis and inhibits cell proliferation. The current study aimed to systematically reveal that TIPE1 regulates the activity of protein arginine methyltransferase (PRMT)-1 and the subsequent methylation of signal transducer and activator of transcription (STAT)-3 to suppress oral squamous cell carcinoma (OSCC) growth. Results showed that TIPE1 was down-regulated in the OSCC cell lines (Tca8113, SCC25, Cal27, SCC15, and HSC27). TIPE1 overexpression significantly inhibited cell proliferation, colony formation, in vivo tumorgenicity, and Ki-67 expression in OSCC. TIPE1 was found to interact with the catalytic region of PRMT1 and inhibited STAT3 methylation. The effects of TIPE1 on OSCC cells were alleviated after PRMT1 overexpression, confirming the importance of this interaction to the tumor-suppressive effects of TIPE1. Together, those findings confirmed that TIPE1 mediated PRMT1 suppression through direct binding to its catalytic domain and then inhibited the methylation and expression of STAT3 in OSCC cells, thereby inhibiting cell growth and tumorgenicity.
    Language English
    Publishing date 2024-03-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2943-9
    ISSN 1525-2191 ; 0002-9440
    ISSN (online) 1525-2191
    ISSN 0002-9440
    DOI 10.1016/j.ajpath.2024.02.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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