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  1. Article ; Online: Separation of Sulfate Anion From Aqueous Solution Governed by Recognition Chemistry

    Si-Qi Chen / Wei Zhao / Biao Wu

    Frontiers in Chemistry, Vol

    A Minireview

    2022  Volume 10

    Abstract: The sulfate anion (SO42–) is known as an end metabolite of cysteine and methionine, and its proper concentration is associated with the expression of key functions in the physiological system. Thus, maintaining sulfate concentration at a precise level is ...

    Abstract The sulfate anion (SO42–) is known as an end metabolite of cysteine and methionine, and its proper concentration is associated with the expression of key functions in the physiological system. Thus, maintaining sulfate concentration at a precise level is of great significance for biology, environments, and industrial productions. Fundamental research for sulfate anion chemistry can help understand sulfate-associated physiological processes and related applications, for example, remediation. In this minireview, we summarized recent research progresses in sulfate recognition and separation using crystallization and liquid–liquid extraction. We focused on the studies wherein molecular recognition is the key element and is considered the driving force for selective sulfate separations from aqueous solution.
    Keywords sulfate recognition ; sulfate separation ; liquid–liquid extraction ; supramolecular chemistry ; anion recognition ; macrocycles ; Chemistry ; QD1-999
    Subject code 540
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Expressions and correlation of blood fibrinogen and IL-33 in patients with cerebral infarction combined with moderate-to-severe periodontitis

    Zhuang-Zhi Wu / Si-Qi Chen / Xiao-Ning He

    Journal of Hainan Medical University, Vol 27, Iss 23, Pp 26-

    2021  Volume 29

    Abstract: Objective: To observe the serum levels of Fibrinogen(Fg), Interleukin - 33(IL-33) in patients with cerebral infarction and periodontitis, and to explore the relationship of cerebral infarction and periodontitis. Methods: 104 subjects were included in ... ...

    Abstract Objective: To observe the serum levels of Fibrinogen(Fg), Interleukin - 33(IL-33) in patients with cerebral infarction and periodontitis, and to explore the relationship of cerebral infarction and periodontitis. Methods: 104 subjects were included in this study. Among them, 23 were patients with CI and CP (group CI + CP), 28 with CI (group CI) , 28 with CP(group CP) and 25 were healthy volunteers (group H). The periodontal indexes and the serum levels of Fg and IL-33 were measured. Results: In groups of CI + CP, CP and CI the Fg and IL-33 were significantly higher than those in the group H (P<0.01). In groups of CI + CP the Fg and Il-33 was higher than group CI and CP (P<0.05). Conclusion: In patients with cerebral infarction with periodontitis, the levels of fibrinogen and interleukin-33 were both increased, and their concentrations were in direct proportion to the periodontal indexes.
    Keywords cerebral infarction ; periodontitis ; fibrinogen ; interleukin-33 ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher Editorial Board of Journal of Hainan Medical University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: First record of the little fire ant, Wasmannia auropunctata (Hymenoptera

    Si-qi CHEN / Yi ZHAO / Yong-yue LU / Hao RAN / Yi-juan XU

    Journal of Integrative Agriculture, Vol 21, Iss 6, Pp 1825-

    Formicidae), in Chinese mainland

    2022  Volume 1829

    Abstract: In January 2022, we received ant specimens collected from three field colonies from Shantou City, Guangdong Province, China. They were identified as the little fire ant, Wasmannia auropunctata, through morphological and molecular analyses. Wasmannia ... ...

    Abstract In January 2022, we received ant specimens collected from three field colonies from Shantou City, Guangdong Province, China. They were identified as the little fire ant, Wasmannia auropunctata, through morphological and molecular analyses. Wasmannia auropunctata is listed as one of the 100 most dangerous invasive species by the International Union for Conservation of Nature (IUCN) and has spread from its native range in South America to every continent except Antarctica. DNA analysis of mitochondrial cytochrome c oxidase subunit I (COI) in nine specimens of W. auropunctata found that they had a close genetic relationship with specimens from Argentina. This study represents the first formal record of the establishment of W. auropunctata outdoor in Chinese mainland. However, the invasion stage and occurrence degree of W. auropunctata in China are not clear to date. The implementation of quarantine measures, investigation of the occurrence and distribution, and development of monitoring and control strategies are needed to actively respond to the threat posed by this highly invasive ant.
    Keywords little fire ant ; morphological identification ; mitochondrial cytochrome c oxidase subunit I ; Agriculture (General) ; S1-972
    Subject code 590
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: An algorithm of image mosaic based on binary tree and eliminating distortion error.

    Zhong Qu / Xue-Ming Wei / Si-Qi Chen

    PLoS ONE, Vol 14, Iss 1, p e

    2019  Volume 0210354

    Abstract: The traditional image mosaic result based on SIFT feature points extraction, to some extent, has distortion errors: the larger the input image set, the greater the spliced panoramic distortion. To achieve the goal of creating a high-quality panorama, a ... ...

    Abstract The traditional image mosaic result based on SIFT feature points extraction, to some extent, has distortion errors: the larger the input image set, the greater the spliced panoramic distortion. To achieve the goal of creating a high-quality panorama, a new and improved algorithm based on the A-KAZE feature is proposed in this paper. This includes changing the way reference image are selected and putting forward a method for selecting a reference image based on the binary tree model, which takes the input image set as the leaf node set of a binary tree and uses the bottom-up approach to construct a complete binary tree. The root node image of the binary tree is the ultimate panorama obtained by stitching. Compared with the traditional way, the novel method improves the accuracy of feature points detection and enhances the stitching quality of the panorama. Additionally, the improved method proposes an automatic image straightening model to rectify the panorama, which further improves the panoramic distortion. The experimental results show that the proposed method cannot only enhance the efficiency of image stitching processing, but also reduce the panoramic distortion errors and obtain a better quality panoramic result.
    Keywords Medicine ; R ; Science ; Q
    Subject code 006
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Biologics for psoriasis patients under 18 years of age

    Yu-Xin Zheng / Li-Ran Ye / Bing-Xi Yan / Si-Qi Chen / Sui-Qing Cai / Xiao-Yong Man

    Frontiers in Medicine, Vol

    Real-world evidence from the Chinese psoriasis real world evidence research group

    2022  Volume 9

    Abstract: BackgroundTreatment for pediatric psoriasis is challenging because of the lack of real-world evidence, especially for biological therapies.ObjectivesThis study evaluated the efficacy and safety of biologics in children with psoriasis based on real-world ... ...

    Abstract BackgroundTreatment for pediatric psoriasis is challenging because of the lack of real-world evidence, especially for biological therapies.ObjectivesThis study evaluated the efficacy and safety of biologics in children with psoriasis based on real-world evidence.MethodsPediatric psoriasis patients aged <18 years who were treated with biologics in our hospital (2020–2022) were prospectively analyzed. Patients treated with adalimumab, secukinumab, or ixekizumab were followed up for at least 16 weeks, and 22 of 38 patients completed the 52-week observation period. Dermatologist raters were blinded to ensure the reliability of the PASI, BSA, and PGA score assessments. PASI 75 or PGA 0/1 at week 12 represented an efficient indicator.ResultsThirty-eight patients (20 males and 18 females; median age, 12.6 ± 4.1 years) were enrolled, and none were lost to follow-up. All participants were diagnosed with psoriasis, including plaque psoriasis (n = 36), nail psoriasis (n = 1), and pustular psoriasis (n = 1). Within 12 weeks, all patients achieved scores above PASI 75 and PGA 0/1. The average time to reach PASI 75 was 4.3 ± 2.0, 3.2 ± 1.8, and 2.4 ± 0.4 weeks in patients using adalimumab, secukinumab, and ixekizumab, respectively, and, 27.2% (3/11), 86.4% (19/22), and 75.0% (3/4) of these patients achieved PASI 100 at week 12, respectively. Moreover, 18 of 20 patients with plaque psoriasis maintained ≥PASI 75 after 52 weeks. The most commonly reported adverse effect was upper respiratory tract infection, and no severe adverse effects were reported.ConclusionsOur real-world data demonstrated the safety and effectiveness of adalimumab, secukinumab, and ixekizumab in children with psoriasis.
    Keywords pediatric psoriasis ; biologics ; adalimumab ; secukinumab ; ixekizumab ; Medicine (General) ; R5-920
    Subject code 616
    Language English
    Publishing date 2022-09-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: The Ras/ERK signaling pathway couples antimicrobial peptides to mediate resistance to dengue virus in Aedes mosquitoes.

    Wen-Quan Liu / Si-Qi Chen / Hao-Qiang Bai / Qi-Mei Wei / Sheng-Nan Zhang / Chen Chen / Yi-Han Zhu / Tang-Wei Yi / Xiao-Pu Guo / Si-Yuan Chen / Meng-Jie Yin / Chen-Feng Sun / Shao-Hui Liang

    PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e

    2020  Volume 0008660

    Abstract: Aedes mosquitoes can transmit dengue and several other severe vector-borne viral diseases, thereby influencing millions of people worldwide. Insects primarily control and clear the viral infections via their innate immune systems. Mitogen-Activated ... ...

    Abstract Aedes mosquitoes can transmit dengue and several other severe vector-borne viral diseases, thereby influencing millions of people worldwide. Insects primarily control and clear the viral infections via their innate immune systems. Mitogen-Activated Protein Kinases (MAPKs) and antimicrobial peptides (AMPs) are both evolutionarily conserved components of the innate immune systems. In this study, we investigated the role of MAPKs in Aedes mosquitoes following DENV infection by using genetic and pharmacological approaches. We demonstrated that knockdown of ERK, but not of JNK or p38, significantly enhances the viral replication in Aedes mosquito cells. The Ras/ERK signaling is activated in both the cells and midguts of Aedes mosquitoes following DENV infection, and thus plays a role in restricting the viral infection, as both genetic and pharmacological activation of the Ras/ERK pathway significantly decreases the viral titers. In contrast, inhibition of the Ras/ERK pathway enhances DENV infection. In addition, we identified a signaling crosstalk between the Ras/ERK pathway and DENV-induced AMPs in which defensin C participates in restricting DENV infection in Aedes mosquitoes. Our results reveal that the Ras/ERK signaling pathway couples AMPs to mediate the resistance of Aedes mosquitoes to DENV infection, which provides a new insight into understanding the crosstalk between MAPKs and AMPs in the innate immunity of mosquito vectors during the viral infection.
    Keywords Arctic medicine. Tropical medicine ; RC955-962 ; Public aspects of medicine ; RA1-1270
    Subject code 570
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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