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  1. Book ; Thesis: Änderungsgenehmigungen im Atom- und Strahlenschutzrecht

    Siegmann, Dirk

    (Studien zum internationalen Wirtschaftsrecht und Atomenergierecht ; 84)

    1993  

    Author's details Dirk Siegmann
    Series title Studien zum internationalen Wirtschaftsrecht und Atomenergierecht ; 84
    Language German
    Size 171 S.
    Publisher Heymann
    Publishing place Köln u.a.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Göttingen, 1992
    ISBN 3452226913 ; 9783452226914
    Database Former special subject collection: coastal and deep sea fishing

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  2. Book ; Thesis: Änderungsgenehmigungen im Atom- und Strahlenschutzrecht

    Siegmann, Dirk

    (Studien zum internationalen Wirtschaftsrecht und Atomenergierecht ; 84)

    1993  

    Author's details Dirk Siegmann
    Series title Studien zum internationalen Wirtschaftsrecht und Atomenergierecht ; 84
    Keywords Atomrecht. Genehmigung
    Language German
    Size 171 S.
    Publisher Heymann
    Publishing place Köln u.a.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Göttingen, 1992
    ISBN 3452226913 ; 9783452226914
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Book: Aenderungsgenehmigungen im Atom- und Strahlenschutzrecht

    Siegmann, Dirk

    1993  Volume 84, Page(s) 171

    Keywords Atomrecht ; Strahlenschutzrecht ; Strahlenschutz ; Strahlenschutzverordnung ; Strahlenschutzvorsorgegesetz ; Aenderungsgenehmigung
    Language German
    Document type Book
    Database OPAC and Environmental database (ULIDAT) of The Federal Environment Agency (UBA)

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  4. Article: Stimulation of quiescent 3T3 cells by phosphatidic acid-containing liposomes.

    Siegmann, D W

    Biochemical and biophysical research communications

    1987  Volume 145, Issue 1, Page(s) 228–233

    Abstract: Liposomes containing phosphatidic acid were capable of stimulating DNA synthesis in quiescent Swiss 3T3 cells while liposomes composed of other phospholipids were not. These results show that liposomes, which are usually employed to deliver non-lipid ... ...

    Abstract Liposomes containing phosphatidic acid were capable of stimulating DNA synthesis in quiescent Swiss 3T3 cells while liposomes composed of other phospholipids were not. These results show that liposomes, which are usually employed to deliver non-lipid molecules into cells, can themselves have profound effects on cell growth. The possible mechanism of phosphatidic acid-mediated cell stimulation and its relation to other growth factors are discussed.
    MeSH term(s) Animals ; Cell Division/drug effects ; Cells, Cultured ; DNA Replication/drug effects ; Kinetics ; Liposomes ; Mice ; Phosphatidic Acids/pharmacology
    Chemical Substances Liposomes ; Phosphatidic Acids
    Language English
    Publishing date 1987-05-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205723-2
    ISSN 0006-291X ; 0006-291X
    ISSN (online) 0006-291X
    ISSN 0006-291X
    DOI 10.1016/0006-291x(87)91310-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: TEPPICHBODEN IM KRANKENHAUS (ZUSAMMENFASSUNG VON 2 TITELN)

    Siegmann D

    Teppich- und Fussbodenzeitung

    1973  Volume 21, Issue 7, Page(s) 29–31

    Keywords Einrichtung und Ausstattung ; Teppichboden ; Krankenhaus ; Deutschland
    Language German
    Size zahlreiche Literaturhinweise
    Publishing place Guenzburg
    Document type Article
    ISSN 0342-6149
    Database Health Care Literature Information Network (HECLINET)

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  6. Article: TEPPICHBODEN IM KRANKENHAUS (ZUSAMMENFASSUNG VON 2 TITELN)

    Siegmann D

    Teppich- und Fussbodenzeitung

    1973  Volume 21, Issue 7, Page(s) 29–31

    Keywords Einrichtung und Ausstattung ; Teppichboden ; Krankenhaus ; Deutschland
    Language German
    Size zahlreiche Literaturhinweise
    Publishing place Guenzburg
    Document type Article
    ISSN 0342-6149
    Database bibnet.org

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  7. Article ; Online: New Constraint on the Local Relic Neutrino Background Overdensity with the First KATRIN Data Runs.

    Aker, M / Batzler, D / Beglarian, A / Behrens, J / Berlev, A / Besserer, U / Bieringer, B / Block, F / Bobien, S / Bornschein, B / Bornschein, L / Böttcher, M / Brunst, T / Caldwell, T S / Carney, R M D / Chilingaryan, S / Choi, W / Debowski, K / Descher, M /
    Díaz Barrero, D / Doe, P J / Dragoun, O / Drexlin, G / Edzards, F / Eitel, K / Ellinger, E / Engel, R / Enomoto, S / Felden, A / Formaggio, J A / Fränkle, F M / Franklin, G B / Friedel, F / Fulst, A / Gauda, K / Gavin, A S / Gil, W / Glück, F / Grössle, R / Gumbsheimer, R / Hannen, V / Haußmann, N / Helbing, K / Hickford, S / Hiller, R / Hillesheimer, D / Hinz, D / Höhn, T / Houdy, T / Huber, A / Jansen, A / Karl, C / Kellerer, F / Kellerer, J / Kleifges, M / Klein, M / Köhler, C / Köllenberger, L / Kopmann, A / Korzeczek, M / Kovalík, A / Krasch, B / Krause, H / La Cascio, L / Lasserre, T / Le, T L / Lebeda, O / Lehnert, B / Lokhov, A / Machatschek, M / Malcherek, E / Mark, M / Marsteller, A / Martin, E L / Melzer, C / Mertens, S / Mostafa, J / Müller, K / Neumann, H / Niemes, S / Oelpmann, P / Parno, D S / Poon, A W P / Poyato, J M L / Priester, F / Ráliš, J / Ramachandran, S / Robertson, R G H / Rodejohann, W / Rodenbeck, C / Röllig, M / Röttele, C / Ryšavý, M / Sack, R / Saenz, A / Salomon, R / Schäfer, P / Schimpf, L / Schlösser, M / Schlösser, K / Schlüter, L / Schneidewind, S / Schrank, M / Schwemmer, A / Šefčík, M / Sibille, V / Siegmann, D / Slezák, M / Spanier, F / Steidl, M / Sturm, M / Telle, H H / Thorne, L A / Thümmler, T / Titov, N / Tkachev, I / Urban, K / Valerius, K / Vénos, D / Vizcaya Hernández, A P / Weinheimer, C / Welte, S / Wendel, J / Wiesinger, C / Wilkerson, J F / Wolf, J / Wüstling, S / Wydra, J / Xu, W / Zadoroghny, S / Zeller, G

    Physical review letters

    2022  Volume 129, Issue 1, Page(s) 11806

    Abstract: We report on the direct search for cosmic relic neutrinos using data acquired during the first two science campaigns of the KATRIN experiment in 2019. Beta-decay electrons from a high-purity molecular tritium gas source are analyzed by a high-resolution ... ...

    Abstract We report on the direct search for cosmic relic neutrinos using data acquired during the first two science campaigns of the KATRIN experiment in 2019. Beta-decay electrons from a high-purity molecular tritium gas source are analyzed by a high-resolution MAC-E filter around the end point at 18.57 keV. The analysis is sensitive to a local relic neutrino overdensity ratio of η<9.7×10^{10}/α (1.1×10^{11}/α) at a 90% (95%) confidence level with α=1 (0.5) for Majorana (Dirac) neutrinos. A fit of the integrated electron spectrum over a narrow interval around the end point accounting for relic neutrino captures in the tritium source reveals no significant overdensity. This work improves the results obtained by the previous neutrino mass experiments at Los Alamos and Troitsk. We furthermore update the projected final sensitivity of the KATRIN experiment to η<1×10^{10}/α at 90% confidence level, by relying on updated operational conditions.
    Language English
    Publishing date 2022-07-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.129.011806
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Bound on 3+1 Active-Sterile Neutrino Mixing from the First Four-Week Science Run of KATRIN.

    Aker, M / Altenmüller, K / Beglarian, A / Behrens, J / Berlev, A / Besserer, U / Bieringer, B / Blaum, K / Block, F / Bornschein, B / Bornschein, L / Böttcher, M / Brunst, T / Caldwell, T S / La Cascio, L / Chilingaryan, S / Choi, W / Díaz Barrero, D / Debowski, K /
    Deffert, M / Descher, M / Doe, P J / Dragoun, O / Drexlin, G / Dyba, S / Edzards, F / Eitel, K / Ellinger, E / Engel, R / Enomoto, S / Fedkevych, M / Felden, A / Formaggio, J A / Fränkle, F M / Franklin, G B / Friedel, F / Fulst, A / Gauda, K / Gil, W / Glück, F / Grössle, R / Gumbsheimer, R / Höhn, T / Hannen, V / Haußmann, N / Helbing, K / Hickford, S / Hiller, R / Hillesheimer, D / Hinz, D / Houdy, T / Huber, A / Jansen, A / Köllenberger, L / Karl, C / Kellerer, J / Kippenbrock, L / Klein, M / Kopmann, A / Korzeczek, M / Kovalík, A / Krasch, B / Krause, H / Lasserre, T / Le, T L / Lebeda, O / Le Guennic, N / Lehnert, B / Lokhov, A / Lopez Poyato, J M / Müller, K / Machatschek, M / Malcherek, E / Mark, M / Marsteller, A / Martin, E L / Melzer, C / Mertens, S / Niemes, S / Oelpmann, P / Osipowicz, A / Parno, D S / Poon, A W P / Priester, F / Röllig, M / Röttele, C / Rest, O / Robertson, R G H / Rodenbeck, C / Ryšavý, M / Sack, R / Saenz, A / Schaller, A / Schäfer, P / Schimpf, L / Schlösser, M / Schlösser, K / Schlüter, L / Schrank, M / Schulz, B / Šefčík, M / Seitz-Moskaliuk, H / Sibille, V / Siegmann, D / Slezák, M / Spanier, F / Steidl, M / Sturm, M / Sun, M / Telle, H H / Thümmler, T / Thorne, L A / Titov, N / Tkachev, I / Trost, N / Vénos, D / Valerius, K / Vizcaya Hernández, A P / Wüstling, S / Weber, M / Weinheimer, C / Weiss, C / Welte, S / Wendel, J / Wilkerson, J F / Wolf, J / Xu, W / Yen, Y-R / Zadoroghny, S / Zeller, G

    Physical review letters

    2021  Volume 126, Issue 9, Page(s) 91803

    Abstract: We report on the light sterile neutrino search from the first four-week science run of the KATRIN experiment in 2019. Beta-decay electrons from a high-purity gaseous molecular tritium source are analyzed by a high-resolution MAC-E filter down to 40 eV ... ...

    Abstract We report on the light sterile neutrino search from the first four-week science run of the KATRIN experiment in 2019. Beta-decay electrons from a high-purity gaseous molecular tritium source are analyzed by a high-resolution MAC-E filter down to 40 eV below the endpoint at 18.57 keV. We consider the framework with three active neutrinos and one sterile neutrino. The analysis is sensitive to the mass, m_{4}, of the fourth mass state for m_{4}^{2}≲1000  eV^{2} and to active-to-sterile neutrino mixing down to |U_{e4}|^{2}≳2×10^{-2}. No significant spectral distortion is observed and exclusion bounds on the sterile mass and mixing are reported. These new limits supersede the Mainz results for m_{4}^{2}≲1000  eV^{2} and improve the Troitsk bound for m_{4}^{2}<30  eV^{2}. The reactor and gallium anomalies are constrained for 100<Δm_{41}^{2}<1000  eV^{2}.
    Language English
    Publishing date 2021-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.126.091803
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Origin and characterization of short DNA chains in Escherichia coli.

    Siegmann, D W / Werner, R

    European journal of biochemistry

    1981  Volume 120, Issue 3, Page(s) 497–509

    Abstract: One of the major problems in the study of DNA replications involves the presence of numerous short, non-nascent DNA chains in the cell. Such chains often contaminate nascent DNA preparations, making accurate analysis of the replicative DNA difficult. ... ...

    Abstract One of the major problems in the study of DNA replications involves the presence of numerous short, non-nascent DNA chains in the cell. Such chains often contaminate nascent DNA preparations, making accurate analysis of the replicative DNA difficult. This complication can be avoided by the use of hydroxyapatite chromatography. Previous results from this laboratory had shown that short nascent DNA chains could be eluted from hydroxyapatite at low phosphate concentrations because of their non-covalent association with protein. Additional data now indicate that this isolation procedure yields a DNA preparation which contains only nascent DNA and is essentially free of non-nascent chains. 5'-Terminal labelling patterns and molecular weight distributions show that only nascent DNA chains from the DNA-protein complex and can therefore be separated from non-nascent chains if the isolation is performed under non-denaturing conditions. The protein involved in the complex appears to be rather specific for DNA chains in the replication fork since short chains resulting from the excision of dUMP immediately after replication also form the DNA-protein complex. Using this isolation technique, the 5'-terminal nucleotides of nascent DNA chains were determined in an effort to learn something about the chain initiation process. DNA was pulse-labeled in several ways, purified by hydroxyapatite chromatography, and labeled at the 5' end with [32P]phosphate. Two-dimensional thin-layer chromatography of the 32P-labeled nucleotides, obtained after enzymatic hydrolysis, revealed that all four deoxyribonucleotides are present at the 5' end in approximately equal amounts. In most cases, this 5'-terminal nucleotide distribution does not vary significantly, even when the conditions of pulse-labeling are changed. Only if the cells are allowed to run out of thymine is a variation in the relative amounts of 5'-end nucleotides detected. In this case, the amount of dTMP at the 5' end decreases significantly, reflecting the low thymine levels and indicating that the cell can compensate for this deficiency by utilizing other available nucleotides. From these results, it appears that DNA chain initiation is essentially random with respect to the nucleotide used in the initiation process.
    MeSH term(s) Chemical Phenomena ; Chemistry ; Chromatography/methods ; DNA Replication ; DNA, Bacterial/metabolism ; Deoxyribonucleotides/analysis ; Escherichia coli/metabolism ; Molecular Weight
    Chemical Substances DNA, Bacterial ; Deoxyribonucleotides
    Language English
    Publishing date 1981-12
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 3032-6
    ISSN 1432-1033 ; 0014-2956
    ISSN (online) 1432-1033
    ISSN 0014-2956
    DOI 10.1111/j.1432-1033.1981.tb05728.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Novel structure at 5'-ends of nascent DNA chains.

    Siegmann, D W / Werner, R

    Proceedings of the National Academy of Sciences of the United States of America

    1976  Volume 73, Issue 10, Page(s) 3438–3442

    Abstract: Because of their association with protein short nascent DNA chains in Escherichia coli can be separated from other cellular DNA by chromatography on hydroxylapatite. Protein-free DNA chains of less than 500 nucleotides in length are resistant to ... ...

    Abstract Because of their association with protein short nascent DNA chains in Escherichia coli can be separated from other cellular DNA by chromatography on hydroxylapatite. Protein-free DNA chains of less than 500 nucleotides in length are resistant to degradation from the 5'-end by alkaline phosphatase [orthophosphoric-monoester phosphohydrolase (alkaline optimum); EC 3.1.3.1] and spleen phosphodiesterase (oligonucleate 3'-nucleotidohydrolase; EC 3.1.4.18). In contrast, DNA chains containing more than 500 nucleotides are degradable. From these results we conclude that short nascent DNA chains are structurally modified at their 5'-ends. The nature of this structure and its possible functions are discussed.
    MeSH term(s) Alkaline Phosphatase/metabolism ; Animals ; DNA Replication ; DNA, Bacterial/analysis ; DNA, Bacterial/biosynthesis ; Dogs ; Molecular Weight ; Phosphoric Diester Hydrolases/metabolism
    Chemical Substances DNA, Bacterial ; Alkaline Phosphatase (EC 3.1.3.1) ; Phosphoric Diester Hydrolases (EC 3.1.4.-)
    Language English
    Publishing date 1976-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.73.10.3438
    Database MEDical Literature Analysis and Retrieval System OnLINE

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