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  1. Article ; Online: Comparing the SARS-CoV-2-specific antibody response in human milk after homologous and heterologous booster vaccinations

    Sien J. Mulleners / Hannah G. Juncker / Eliza J. M. Ruhé / Aniko Korosi / Johannes B. van Goudoever / Marit J. van Gils / Britt J. van Keulen

    Communications Biology, Vol 6, Iss 1, Pp 1-

    2023  Volume 7

    Abstract: The longitudinal SARS-CoV-2-specific antibody response in human milk of lactating women receiving an mRNA-based booster vaccine indicates that both homologous and heterologous boosters enhance SARS-CoV-2-specific antibodies in human milk. ...

    Abstract The longitudinal SARS-CoV-2-specific antibody response in human milk of lactating women receiving an mRNA-based booster vaccine indicates that both homologous and heterologous boosters enhance SARS-CoV-2-specific antibodies in human milk.
    Keywords Biology (General) ; QH301-705.5
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Comparison of SARS-CoV-2-Specific Antibodies in Human Milk after mRNA-Based COVID-19 Vaccination and Infection

    Hannah G. Juncker / Sien J. Mulleners / Marit J. van Gils / Tom P. L. Bijl / Christianne J. M. de Groot / Dasja Pajkrt / Aniko Korosi / Johannes B. van Goudoever / Britt J. van Keulen

    Vaccines, Vol 9, Iss 1475, p

    2021  Volume 1475

    Abstract: SARS-CoV-2-specific antibodies are secreted into human milk of infected or vaccinated lactating women and might provide protection to the breastfed infant against COVID-19. Differences in antibody response after these types of exposure are unknown. In ... ...

    Abstract SARS-CoV-2-specific antibodies are secreted into human milk of infected or vaccinated lactating women and might provide protection to the breastfed infant against COVID-19. Differences in antibody response after these types of exposure are unknown. In this longitudinal cohort study, we compared the antibody response in human milk following SARS-CoV-2 vaccination or infection. We analyzed 448 human milk samples of 28 lactating women vaccinated with the SARS-CoV-2 vaccine BNT162b2 as well as 82 human milk samples of 18 lactating women with a prior SARS-CoV-2 infection. The levels of SARS-CoV-2-specific IgA in human milk were determined over a period of 70 days both after vaccination and infection. The amount of SARS-CoV-2-specific IgA in human milk was similar after SARS-CoV-2 vaccination and infection. After infection, the variability in IgA levels was higher than after vaccination. Two participants with detectable IgA prior to vaccination were analyzed separately and showed higher IgA levels following vaccination compared to both groups. In conclusion, breastfed infants of mothers who have been vaccinated with the BNT162b2 vaccine receive human milk with similar amounts of SARS-CoV-2-specific antibodies compared to infants of previously infected mothers.
    Keywords breastmilk ; immunization (vaccination) ; SARS-CoV-2 ; immunoglobulin A ; BNT162b2 mRNA COVID-19 vaccine ; COVID-19 ; Medicine ; R
    Subject code 630
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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