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  1. Book ; Online: New Frontiers in Cementitious and Lime-Based Materials and Composites

    Signorini, Cesare / Sola, Antonella / Chakraborty, Sumit / Volpini, Valentina

    2022  

    Keywords Technology: general issues ; History of engineering & technology ; durability ; hardened properties ; green composite ; fresh properties ; recycled concrete aggregates ; natural coarse aggregates ; enzyme-induced calcite precipitation ; microbial-induced calcite precipitation ; geotechnical engineering ; geoenvironmental engineering ; precast concrete wall ; interfacial bonding strength ; joint concrete ; interface processing ; washed rough surface ; roughness ; storage time ; cement mortar ; End-of-Life Tyre ; waste ; surface treatment ; compressive strength ; flexural strength ; workability ; fly ash ; freezing shaft sinking ; shaft lining structure ; uneven pressure ; hybrid fiber-reinforced concrete ; crack ; autogenous self-healing ; curing conditions ; supplementary cementitious materials (SCMs) ; GRC-PC ; integrated wall panels ; composite method ; shrinkage properties ; dissipation energy density ; high-strength concrete ; Weibull distribution ; damage mechanics ; constitutive model ; repeated impact ; ACI 544-2R ; high temperatures ; fire ; residual strength ; lime-cement mortar ; air-entrained agent ; heritage conservation ; reconstruction and restoration of historical buildings ; properties ; mechanical ; electrical resistivity ; ecofriendly ternary concrete ; SCBA ; SF ; coastal cemented soil ; nano silica ; iron tailings ; mechanical properties ; microscopic mechanism ; granite dust ; stabilizer ; particle size ; plasticity ; unconfined compression strength ; cement ; lime ; sustainable materials ; fibre-reinforced composite ; recycled aggregates
    Language 0|e
    Size 1 electronic resource (264 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021608760
    ISBN 9783036535449 ; 3036535446
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Re: Marie-Aimée Perrouine-Verbe, Marcus J. Drake, Laura Thomas. The Challenges of Real-life Bladder Diary Use and Interpretation. Eur Urol Focus 2022;8:11-7.

    Signorini, Claudia / Carmignani, Luca

    European urology focus

    2022  Volume 8, Issue 6, Page(s) 1871

    MeSH term(s) Humans ; Urinary Bladder
    Language English
    Publishing date 2022-05-11
    Publishing country Netherlands
    Document type Letter ; Comment
    ISSN 2405-4569
    ISSN (online) 2405-4569
    DOI 10.1016/j.euf.2022.04.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A new Rayleigh-like wave in guided propagation of antiplane waves in couple stress materials.

    Nobili, A / Radi, E / Signorini, C

    Proceedings. Mathematical, physical, and engineering sciences

    2020  Volume 476, Issue 2235, Page(s) 20190822

    Abstract: Motivated by the unexpected appearance of shear horizontal Rayleigh surface waves, we investigate the mechanics of antiplane wave reflection and propagation in couple stress (CS) elastic materials. Surface waves arise by mode conversion at a free surface, ...

    Abstract Motivated by the unexpected appearance of shear horizontal Rayleigh surface waves, we investigate the mechanics of antiplane wave reflection and propagation in couple stress (CS) elastic materials. Surface waves arise by mode conversion at a free surface, whereby bulk travelling waves trigger inhomogeneous modes. Indeed, Rayleigh waves are perturbations of the travelling mode and stem from its reflection at grazing incidence. As is well known, they correspond to the real zeros of the Rayleigh function. Interestingly, we show that the same generating mechanism sustains a new inhomogeneous wave, corresponding to a purely imaginary zero of the Rayleigh function. This wave emerges from 'reflection' of a bulk standing mode: This produces a new type of Rayleigh-like wave that travels
    Language English
    Publishing date 2020-03-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 209241-4
    ISSN 1471-2946 ; 1364-5021 ; 0962-8444 ; 0080-4630 ; 0950-1207
    ISSN (online) 1471-2946
    ISSN 1364-5021 ; 0962-8444 ; 0080-4630 ; 0950-1207
    DOI 10.1098/rspa.2019.0822
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 46/95: Show issues

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  4. Article ; Online: Re: Maria S. Lindgren, Peter Bue, Nessn Azawi, et al. The DaBlaCa-13 Study: Short-term, Intensive Chemoresection Versus Standard Adjuvant Intravesical Instillations in Non-muscle-invasive Bladder Cancer-A Randomized Controlled Trial. Eur Urol 2020;78:856-62.

    Signorini, Claudia / Maffezzini, Massimo

    European urology

    2021  Volume 79, Issue 5, Page(s) e135–e136

    Language English
    Publishing date 2021-02-13
    Publishing country Switzerland
    Document type Letter ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2021.01.034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1247: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 294: Show issues

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  5. Article: Mechanical Performance of Fiber Reinforced Cement Composites Including Fully-Recycled Plastic Fibers

    Signorini, Cesare / Volpini, Valentina

    Fibers. 2021 Mar. 01, v. 9, no. 3

    2021  

    Abstract: The use of virgin and recycled plastic macro fibers as reinforcing elements in construction materials has recently gained increasing attention from researchers. Specifically, recycled fibers have become more attractive owing to their large-scale ... ...

    Abstract The use of virgin and recycled plastic macro fibers as reinforcing elements in construction materials has recently gained increasing attention from researchers. Specifically, recycled fibers have become more attractive owing to their large-scale availability, negligible cost, and low environmental footprint. In this work, we investigate the benefits related to the use of fully-recycled synthetic fibers as dispersed reinforcement in Fiber Reinforced Cement Composites (FRCCs). In light of the reference performance of FRCCs including virgin polypropylene (PP) fibers only, the mechanical response of composites reinforced with polyolefin filaments treated with a sol-gel silica coating and polyethylene terephthalate (PET)/polyethylene (PE) cylindrical draw-wire fibers is here assessed through three-point bending tests. Remarkably, recycled polyolefins lead to a notable enhancement in terms of peak strength and post-crack energy dissipation capability. This improvement is ascribed to both the flattened shape of fibers and the surface coating, which turns out to be very effective at strengthening the fiber-to-matrix bond. On the other hand, PET/PE fibrous reinforcement generally leads to a lower toughness, if compared to the virgin fibers. However, no reduction in terms of peak stress is evidenced. Balancing the significance of mechanical performance and environmental sustainability in the framework of a circular economy approach, both fully-recycled fibers at hand can be regarded as promising candidates for innovative structural applications.
    Keywords cement ; circular economy ; ecological footprint ; energy ; polyethylene terephthalates ; polyolefin ; polypropylenes ; silica
    Language English
    Dates of publication 2021-0301
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2723193-8
    ISSN 2079-6439
    ISSN 2079-6439
    DOI 10.3390/fib9030016
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: Targeting functionalised carbon nanotubes at the interphase of Textile Reinforced Mortar (TRM) composites

    Signorini, Cesare / Nobili, Andrea

    Composites. 2021 May, v. 144

    2021  

    Abstract: Tensile performance of textile reinforced inorganic matrix composites strongly depends on the matrix-to-fabric bond strength, that is the weak chain in the system. In this work, we investigate the role of multi-walled carbon nanotubes (MWCNT) dispersion ... ...

    Abstract Tensile performance of textile reinforced inorganic matrix composites strongly depends on the matrix-to-fabric bond strength, that is the weak chain in the system. In this work, we investigate the role of multi-walled carbon nanotubes (MWCNT) dispersion in an amorphous silica nano-coating for AR-glass and carbon fabric Textile Reinforced Mortar (TRM) composites. Two lime mortars are considered at 56-day curing. Comparative mechanical testing in uni-axial tension show remarkable enhancements in terms of mean ductility, strength and energy dissipation capabilities. Besides, coating successfully hinders telescopic failure and delamination, which significantly narrows data scattering and benefits design limits. Crack pattern analysis reveals that coating promotes diffuse cracking in the specimen, with gradual and progressive damage buildup. Indeed, mean crack width and mean crack spacing are consistently reduced. BET, optical and E-SEM microscopy supports the action mechanism of the coating, that promotes wettability, surface roughening and imparts a remarkable increase in the specific surface area of the reinforcement.
    Keywords carbon ; carbon nanotubes ; delamination ; energy ; fabrics ; interphase ; microscopy ; silica ; surface area ; wettability
    Language English
    Dates of publication 2021-05
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2012223-8
    ISSN 1359-835X
    ISSN 1359-835X
    DOI 10.1016/j.compositesa.2021.106330
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Redox Homeostasis and Nrf2-Regulated Mechanisms Are Relevant to Male Infertility.

    Signorini, Cinzia / Saso, Luciano / Ghareghomi, Somayyeh / Telkoparan-Akillilar, Pelin / Collodel, Giulia / Moretti, Elena

    Antioxidants (Basel, Switzerland)

    2024  Volume 13, Issue 2

    Abstract: Infertility represents a significant global health challenge, affecting more than 12% of couples worldwide, and most cases of infertility are caused by male factors. Several pathological pathways are implicated in male infertility. The main mechanisms ... ...

    Abstract Infertility represents a significant global health challenge, affecting more than 12% of couples worldwide, and most cases of infertility are caused by male factors. Several pathological pathways are implicated in male infertility. The main mechanisms involved are driven by the loss of reduction-oxidation (redox) homeostasis and the resulting oxidative damage as well as the chronic inflammatory process. Increased or severe oxidative stress leads to sperm plasma membrane and DNA oxidative damage, dysregulated RNA processing, and telomere destruction. The signaling pathways of these molecular events are also regulated by Nuclear factor-E2-related factor 2 (Nrf2). The causes of male infertility, the role of oxidative stress in male infertility and the Keap1-Nrf2 antioxidant pathway are reviewed. This review highlights the regulatory role of Nrf2 in the balance between oxidants and antioxidants as relevant mechanisms to male fertility. Nrf2 is involved in the regulation of spermatogenesis and sperm quality. Establishing a link between Nrf2 signaling pathways and the regulation of male fertility provides the basis for molecular modulation of inflammatory processes, reactive oxygen species generation, and the antioxidant molecular network, including the Nrf2-regulated antioxidant response, to improve male reproductive outcomes.
    Language English
    Publishing date 2024-02-03
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox13020193
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Human Sperm as an In Vitro Model to Assess the Efficacy of Antioxidant Supplements during Sperm Handling: A Narrative Review.

    Moretti, Elena / Signorini, Cinzia / Corsaro, Roberta / Giamalidi, Maria / Collodel, Giulia

    Antioxidants (Basel, Switzerland)

    2023  Volume 12, Issue 5

    Abstract: Spermatozoa are highly differentiated cells that produce reactive oxygen species (ROS) due to aerobic metabolism. Below a certain threshold, ROS are important in signal transduction pathways and cellular physiological processes, whereas ROS ... ...

    Abstract Spermatozoa are highly differentiated cells that produce reactive oxygen species (ROS) due to aerobic metabolism. Below a certain threshold, ROS are important in signal transduction pathways and cellular physiological processes, whereas ROS overproduction damages spermatozoa. Sperm manipulation and preparation protocols during assisted reproductive procedures-for example, cryopreservation-can result in excessive ROS production, exposing these cells to oxidative damage. Thus, antioxidants are a relevant topic in sperm quality. This narrative review focuses on human spermatozoa as an in vitro model to study which antioxidants can be used to supplement media. The review comprises a brief presentation of the human sperm structure, a general overview of the main items of reduction-oxidation homeostasis and the ambivalent relationship between spermatozoa and ROS. The main body of the paper deals with studies in which human sperm have been used as an in vitro model to test antioxidant compounds, including natural extracts. The presence and the synergic effects of different antioxidant molecules could potentially lead to more effective products in vitro and, in the future, in vivo.
    Language English
    Publishing date 2023-05-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox12051098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Can Dietary n-3 Polyunsaturated Fatty Acids Affect Apelin and Resolvin in Testis and Sperm of Male Rabbits?

    Mattioli, Simona / Moretti, Elena / Castellini, Cesare / Signorini, Cinzia / Corsaro, Roberta / Angelucci, Elisa / Collodel, Giulia

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 17

    Abstract: Apelin and other novel adipokines have been associated with normal and pathological reproductive conditions in humans and animals. In this paper, we used a rabbit model to investigate if apelin and resolvin (RvD1) in testis and sperm are associated with ... ...

    Abstract Apelin and other novel adipokines have been associated with normal and pathological reproductive conditions in humans and animals. In this paper, we used a rabbit model to investigate if apelin and resolvin (RvD1) in testis and sperm are associated with the oxidative status of semen and serum testosterone of rabbits fed different diets enriched with flaxseed (alpha-linolenic acid, ALA) or with fish oil (eicosapentaenoic acid, EPA, docosapentaenoic acid, DPAn-3, and docosahexaenoic acid, DHA). Apelin and RvD1 were detected by ELISA and apelin and the apelin receptor by immunofluorescence. Increased levels of apelin in testes from both enriched diets were shown, particularly in the interstitial tissue of the FLAX group. The FLAX diet enhanced serum testosterone, and both enriched diets showed higher levels of malondialdehyde and RvD1 in the testis. In ejaculated sperm, apelin and its receptor were localized in the entire tail of the control and both treated groups. The ryanodine receptor was investigated in rabbit testis; the fluorescent signal was increased in mature elongated spermatids of the FLAX group. In conclusion, this data seems to indicate that FLAX increases the amount of apelin in testis, suggesting an involvement of this adipokine in male reproduction and probably a role in the resolution of the inflammatory status.
    MeSH term(s) Male ; Animals ; Humans ; Rabbits ; Testis ; Apelin ; Seeds ; Spermatozoa ; Fatty Acids ; Adipokines ; Docosahexaenoic Acids ; Testosterone
    Chemical Substances Apelin ; Fatty Acids ; Adipokines ; Docosahexaenoic Acids (25167-62-8) ; Testosterone (3XMK78S47O)
    Language English
    Publishing date 2023-08-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28176188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  10. Article ; Online: The relevance of sperm morphology in male infertility.

    Moretti, Elena / Signorini, Cinzia / Noto, Daria / Corsaro, Roberta / Collodel, Giulia

    Frontiers in reproductive health

    2022  Volume 4, Page(s) 945351

    Abstract: This brief report concerns the role of human sperm morphology assessment in different fields of male infertility: basic research, genetics, assisted reproduction technologies, oxidative stress. One of the best methods in studying sperm morphology is ... ...

    Abstract This brief report concerns the role of human sperm morphology assessment in different fields of male infertility: basic research, genetics, assisted reproduction technologies, oxidative stress. One of the best methods in studying sperm morphology is transmission electron microscopy (TEM) that enables defining the concept of sperm pathology and classifying alterations in non-systematic and systematic. Non-systematic sperm defects affect head and tail in variable ratio, whereas the rare systematic defects are characterized by a particular anomaly that marks most sperm of an ejaculate. TEM analysis and fluorescence
    Language English
    Publishing date 2022-08-03
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-3153
    ISSN (online) 2673-3153
    DOI 10.3389/frph.2022.945351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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