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Article: The impact of the COVID-19 pandemic on the characteristics of melanoma: a single-centre cohort study.

Śmigielska, Paulina / Sławińska, Martyna / Sikorska, Monika / Sobjanek, Michał

2023 Volume 40, Issue 5, Page(s) 638–641

Abstract: Introduction: The COVID-19 pandemic had, in a broad sense, a negative impact on populational health and well-being. Countries around the world struggled to address a spike in demand for the management of viral pneumonia and, at the same time, to ... ...

Abstract	Introduction: The COVID-19 pandemic had, in a broad sense, a negative impact on populational health and well-being. Countries around the world struggled to address a spike in demand for the management of viral pneumonia and, at the same time, to efficiently treat the conditions which deteriorate severely when the treatment is delayed. Several studies published so far have analysed the impact of the COVID-19 pandemic on skin cancer epidemiology and management, however the results have been inconsistent. Aim: To examine the influence of the COVID-19 pandemic on the cutaneous melanoma epidemiology diagnosed in a tertiary referral centre in Northern Poland. Material and methods: This was a retrospective study that gathered the data on all the cutaneous melanoma cases treated in our facility during the official lockdown period in Poland and compared them to those diagnosed during the corresponding period from before the pandemic. Results: The number of cutaneous melanoma cases diagnosed during the pandemic decreased substantially. Interestingly, it was mostly due to a decrease in the number of patients with cutaneous melanoma localised on the trunk and early melanoma cases (melanoma in situ and pT1a stage). Conclusions: Our data suggest that, similarly to the reports emerging worldwide, the COVID-19 pandemic impaired the capability of our healthcare system to diagnose and treat cutaneous melanoma in our region. The data are limited, and further research will be necessary to determine the whole extent of those changes, especially the long-term effects.
Language	English
Publishing date	2023-11-09
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2596142-1
ISSN	1642-395X
ISSN	1642-395X
DOI	10.5114/ada.2023.132247
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Article ; Online: Diffuse Cutaneous Mastocytosis: A Current Understanding of a Rare Disease.

Rydz, Agnieszka / Lange, Magdalena / Ługowska-Umer, Hanna / Sikorska, Monika / Nowicki, Roman J / Morales-Cabeza, Cristina / Alvarez-Twose, Iván

International journal of molecular sciences

2024 Volume 25, Issue 3

Abstract: Mastocytosis is a heterogeneous disease characterized by the expansion and accumulation of neoplastic mast cells in various tissues. Diffuse cutaneous mastocytosis (DCM) is a rare and most severe form of cutaneous mastocytosis, which typically occurs in ... ...

Abstract	Mastocytosis is a heterogeneous disease characterized by the expansion and accumulation of neoplastic mast cells in various tissues. Diffuse cutaneous mastocytosis (DCM) is a rare and most severe form of cutaneous mastocytosis, which typically occurs in childhood. There have been reports of a familial DCM with specific gene mutations, indicating both sporadic and hereditary factors involved in its pathogenesis. DCM is associated with severe MC mediator-related symptoms and an increased risk of anaphylaxis. The diagnosis is based on the appearance of skin lesions, which typically show generalized thickening, erythroderma, blistering dermographism, and a positive Darier's sign. Recognition, particularly in infants, is challenging due to DCMs resemblance to other bullous skin disorders. Therefore, in unclear cases, a skin biopsy is crucial. Treatment focuses on symptom management, mainly including antihistamines and mast cell stabilizers. In extremely severe cases, systemic steroids, tyrosine kinase inhibitors, phototherapy, or omalizumab may be considered. Patients should be equipped with an adrenaline autoinjector. Herein, we conducted a comprehensive review of literature data on DCM since 1962, which could help to better understand both the management and prognosis of DCM, which depends on the severity of skin lesions, intensity of mediator-related symptoms, presence of anaphylaxis, and treatment response.
MeSH term(s)	Infant ; Humans ; Anaphylaxis/etiology ; Anaphylaxis/pathology ; Rare Diseases/pathology ; Mastocytosis, Cutaneous/diagnosis ; Mastocytosis, Cutaneous/therapy ; Mastocytosis/diagnosis ; Mastocytosis/therapy ; Mastocytosis/pathology ; Skin/pathology ; Lupus Erythematosus, Cutaneous/pathology ; Mast Cells/pathology
Language	English
Publishing date	2024-01-23
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25031401
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Article ; Online: More than a hundred thousand respondents within 48 h: How the power of social media helped to understand pregnancy loss in Poland - A retrospective population-based cohort study.

Wojcicki, Jakub / Wawrysiuk, Sara / Sochacki-Wojcicka, Nicole / Podlinska, Olga / Pietrych, Lukasz / Szpotanska-Sikorska, Monika

European journal of obstetrics, gynecology, and reproductive biology

2023 Volume 289, Page(s) 29–35

Abstract: Background: Miscarriage is defined as the loss of pregnancy before 20-24 weeks of gestation, and it is the most common complication of early pregnancy. The aim of the study was to determine the prevalence and risk factors of spontaneous abortion in the ... ...

Abstract	Background: Miscarriage is defined as the loss of pregnancy before 20-24 weeks of gestation, and it is the most common complication of early pregnancy. The aim of the study was to determine the prevalence and risk factors of spontaneous abortion in the population of Polish females to provide a reference for clinical work. Methods: A cross-sectional self-administered on-line survey was distributed between 4th and 5th of October 2019 in the social media across Poland. A total of 100,026 recipients responded to the questionnaire and 93,636 valid respondents were included in the analyses. Results: Among respondents who had ever been pregnant, 31.2% reported at least one spontaneous abortion. The prevalence of miscarriage varied based on age, parity, place of residence and the education level. The first symptom of miscarriage was a vaginal bleeding (56.2%) and abdominal cramps (25.8%), while 43% of respondents had no symptoms and found out during doctor's visit. No medical assistance was required after complete spontaneous abortion in 39.2% of cases. Conclusions: Miscarriage is a common complication of pregnancy, but it is not yet fully understood. The goal of future medicine is to minimize the medicalization of spontaneous abortion and excessive medical intervention by raising awareness about natural miscarriage route.
MeSH term(s)	Pregnancy ; Female ; Humans ; Abortion, Spontaneous/epidemiology ; Abortion, Spontaneous/etiology ; Poland/epidemiology ; Retrospective Studies ; Cohort Studies ; Cross-Sectional Studies ; Social Media
Language	English
Publishing date	2023-08-12
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	190605-7
ISSN	1872-7654 ; 0301-2115 ; 0028-2243
ISSN (online)	1872-7654
ISSN	0301-2115 ; 0028-2243
DOI	10.1016/j.ejogrb.2023.08.008
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Article: Agminated blue nevi: a case series and updated dermoscopic review.

Sławińska, Martyna / Balicka, Urszula / Kamińska-Winciorek, Grażyna / Sikorska, Monika / Nowicki, Roman J / Sobjanek, Michał

Postepy dermatologii i alergologii

2022 Volume 39, Issue 6, Page(s) 1069–1076

Abstract: Blue nevi, usually presenting as solitary, bluish, asymptomatic macules or nodules, are formed by collections of dermal melanocytes that failed to complete their migration from the neural crest to the dermo-epidermal junction. The term "agminated blue ... ...

Abstract	Blue nevi, usually presenting as solitary, bluish, asymptomatic macules or nodules, are formed by collections of dermal melanocytes that failed to complete their migration from the neural crest to the dermo-epidermal junction. The term "agminated blue nevi" refers to multiple lesions grouped, linear, or arranged in a blashkoid distribution. It is a relatively rare phenomenon with less than 35 cases reported in the literature, but only 14 cases with dermoscopic features. We report another 4 cases along with an updated dermoscopic review.
Language	English
Publishing date	2022-09-09
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2596142-1
ISSN	1642-395X
ISSN	1642-395X
DOI	10.5114/ada.2022.119416
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Article: Significance of Dermoscopy in Association with Clinical Features in Differentiation of Basal Cell Carcinoma and Benign Trichoblastic Tumours.

Sławińska, Martyna / Płaszczyńska, Anna / Lakomy, Joanna / Pastuszak, Krzysztof / Biernat, Wojciech / Sikorska, Monika / Nowicki, Roman J / Sobjanek, Michał

Cancers

2022 Volume 14, Issue 16

Abstract: Background: Although basal cell carcinoma (BCC) can, in the majority of cases, be diagnosed based on clinical and dermoscopic assessment, a potential overlap with benign adnexal skin tumours seems to exist, including trichoblastic tumours (TT). Methods: ... ...

Abstract	Background: Although basal cell carcinoma (BCC) can, in the majority of cases, be diagnosed based on clinical and dermoscopic assessment, a potential overlap with benign adnexal skin tumours seems to exist, including trichoblastic tumours (TT). Methods: Retrospective analysis of clinical and dermoscopic features of benign TT and BCC cases was performed to develop a diagnostic algorithm with a potential utility in clinical practice. Results: In the study, 502 histopathologically confirmed BCC cases were compared with 61 TT (including 44 TB (72.13%), 10 TE (16.39%) and 7 DTE (11.48%]). Patients in the BCC group were statistically older (mean age was 71.4 vs. 64.4 years, respectively; p = 0.009). BCC presented generally as larger tumours (mean tumour size 11.0 vs. 8.2 mm for the TT group; p = 0.001) and was more frequently associated with clinically visible ulceration (59.4% vs. 19.7%, respectively; p < 0.001). Comparison of lesion morphology, clinically visible pigmentation, and anatomical location did not show significant differences between the analysed groups. Dermoscopically visible ulceration was significantly more common in the BCC group compared to the TT group (52.2% vs. 14.8%; p < 0.0001). Pigmented structures, specifically brown dots and brown globules, were significantly more prevalent in the TT group (32.8% vs. 11.4%; p = 0.0001 and 29.5% vs. 8.2%; p <0.0001). Similarly, TT more commonly than BCC showed the presence of cloudy/starry milia-like cysts (26.2% vs. 11.6%; p = 0.0031) and yellow globules (16.4% vs. 7.2%; p = 0.033). Conclusions: Despite differences in frequency of clinical and dermoscopic features between BCC and TT in the studied group, differential diagnosis based on these variables is not reliable. Histopathological examination remains a diagnostic gold standard in differentiation of BCC and TT.
Language	English
Publishing date	2022-08-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers14163964
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Article ; Online: Changes in Knowledge about Umbilical Cord Blood Banking and Genetic Tests among Pregnant Women from Polish Urban and Rural Areas between 2010-2012 and 2017.

Szubert, Maria / Ilowiecka, Malwina / Wilczynski, Jacek / Szpotanska-Sikorska, Monika / Wojtyla, Cezary

International journal of environmental research and public health

2020 Volume 17, Issue 16

Abstract: The aim of this study was to evaluate knowledge of umbilical cord blood (UBC) banking and prenatal genetic diagnosis among pregnant women from rural and urban areas, and how this knowledge changed within a five-year period. A survey by questionnaire was ... ...

Abstract	The aim of this study was to evaluate knowledge of umbilical cord blood (UBC) banking and prenatal genetic diagnosis among pregnant women from rural and urban areas, and how this knowledge changed within a five-year period. A survey by questionnaire was conducted between 2010 and 2012, and in 2017 in public hospitals; the study population comprised 6128 women, with 2797 patients from the years 2010-2012 and 3331 from the year 2017. 41% of the studied population declared that they were living in rural areas. In the 2010-2012 period, fewer women from rural areas knew about UBC banking. In 2017 that same relative difference in knowledge persisted, but the percentage of women who now knew about this procedure rose significantly in both studied groups. Prenatal diagnosis was more familiar for urban inhabitants both in 2010 and 2017 but as with the UBC data, a trend of growing awareness was also seen in pregnant women from rural areas. Knowledge of new techniques such as UBC banking and genetic tests has grown among pregnant women during the time frame of our study, but there is still a need to emphasize the benefits of these two possibilities to pregnant women, especially among rural inhabitants.
MeSH term(s)	Adult ; Blood Banks ; Female ; Fetal Blood ; Genetic Testing ; Humans ; Poland ; Pregnancy ; Pregnant Women ; Rural Population ; Urban Population ; Young Adult
Keywords	covid19
Language	English
Publishing date	2020-08-08
Publishing country	Switzerland
Document type	Journal Article
ISSN	1660-4601
ISSN (online)	1660-4601
DOI	10.3390/ijerph17165744
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Article ; Online: Depression, sexual satisfaction, and other psychological issues in women with polycystic ovary syndrome.

Stapinska-Syniec, Angelika / Grabowska, Klaudia / Szpotanska-Sikorska, Monika / Pietrzak, Bronislawa

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

2018 Volume 34, Issue 7, Page(s) 597–600

Abstract: Polycystic ovary syndrome (PCOS) increases the risk of depression, poor quality of life, and low sexual satisfaction of women. The aim of the study was to evaluate the prevalence of these disorders and to assess the need for psychological consultation at ...

Abstract	Polycystic ovary syndrome (PCOS) increases the risk of depression, poor quality of life, and low sexual satisfaction of women. The aim of the study was to evaluate the prevalence of these disorders and to assess the need for psychological consultation at the time of PCOS diagnosis. A case-control single-center study of 250 women who were diagnosed with PCOS voluntarily filled in an anonymous, interactive questionnaire. The inquiry form included 27 questions covering the woman's characteristics, satisfaction with their outer appearance and sexual life, as well as the Beck Depression Inventory (BDI). Based on the BDI, 52% (130/250) of studied women presented depressive symptoms. This group had significantly higher body mass index (29.5 ± 8.1 vs. 24.6 ± 5.8; p<.001) and a lower level of self-attractiveness than other studied women (3.3 ± 2.2 vs. 5.4 ± 2.3; p<.001). Forty two percent (106/250) of women viewed themselves as unattractive. A correlation between reduced sexual satisfaction and a sense of low attractiveness was noted (r = 0.465, p<.001). Sixty four percent (160/250) of women believed that psychological consultation should be offered to all PCOS women. Treatment of PCOS women should be multidisciplinary and include psychological counseling, especially in obese PCOS women with inadequate family support and dissatisfied with their sexual life.
MeSH term(s)	Adolescent ; Adult ; Body Mass Index ; Case-Control Studies ; Depression/epidemiology ; Depression/etiology ; Female ; Humans ; Middle Aged ; Personal Satisfaction ; Polycystic Ovary Syndrome/complications ; Polycystic Ovary Syndrome/epidemiology ; Polycystic Ovary Syndrome/physiopathology ; Polycystic Ovary Syndrome/psychology ; Quality of Life ; Self Concept ; Sexual Behavior/psychology ; Surveys and Questionnaires ; Young Adult
Language	English
Publishing date	2018-01-16
Publishing country	England
Document type	Journal Article
ZDB-ID	639237-4
ISSN	1473-0766 ; 0951-3590
ISSN (online)	1473-0766
ISSN	0951-3590
DOI	10.1080/09513590.2018.1427713
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Zs.A 2284: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Unintended pregnancies and family planning among women after kidney or liver transplantation.

Szpotanska-Sikorska, Monika / Mazanowska, Natalia / Kociszewska-Najman, Bozena / Wielgos, Miroslaw / Pietrzak, Bronislawa

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

2018 Volume 33, Issue 8, Page(s) 1346–1352

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Adult ; Contraception Behavior/statistics & numerical data ; Cross-Sectional Studies ; Family Planning Services/statistics & numerical data ; Female ; Humans ; Kidney Transplantation ; Liver Transplantation ; Pregnancy ; Pregnancy, Unplanned ; Surveys and Questionnaires ; Time Factors ; Transplant Recipients/statistics & numerical data
Language	English
Publishing date	2018-09-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2077261-0
ISSN	1476-4954 ; 1057-0802 ; 1476-7058
ISSN (online)	1476-4954
ISSN	1057-0802 ; 1476-7058
DOI	10.1080/14767058.2018.1518420
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Zs.A 3510: Show issues

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Article ; Online: Reproductive life planning in women after kidney or liver transplantation.

Szpotanska-Sikorska, Monika / Mazanowska, Natalia / Madej, Anna / Kociszewska-Najman, Bozena / Wielgos, Miroslaw / Pietrzak, Bronislawa

Clinical transplantation

2018 Volume 32, Issue 9, Page(s) e13378

Abstract: Introduction: To estimate reproductive life planning in post-transplant women and to identify factors affecting their pregnancy intentions.: Material and methods: A survey study on reproductive life planning was conducted in 217 women of childbearing ...

Abstract	Introduction: To estimate reproductive life planning in post-transplant women and to identify factors affecting their pregnancy intentions. Material and methods: A survey study on reproductive life planning was conducted in 217 women of childbearing age who underwent kidney or liver transplantation. The results were compared with data obtained from 816 healthy women surveyed by the Polish Centre for Public Opinion Research. Data were summarized using descriptive statistics. Results: Post-transplant women express a similar desire to have a child as women in the general population (42% vs 40%, respectively; P = 0.638). A comparable majority of childless women would like to give birth (65% vs 77%, P = 0.350). More post-transplant women who have one child give up on future procreation plans (80% vs 46%, P < 0.001). The main factors affecting post-transplant reproductive life planning were age (OR:0.79; 95% CI: 0.73-0.85), number of live births (OR:0.22; 95% CI: 0.11-0.43), and use of drugs contraindicated in pregnancy (OR:0.27; 95% CI: 0.11-0.63). Conclusions: Women after kidney or liver transplantation, especially childless, have a similar willingness to become mothers as those in the general population. For post-transplant women who have already given birth, it is worth considering contraceptive counseling because these women more often choose to not attempt another pregnancy.
MeSH term(s)	Adolescent ; Adult ; Attitude to Health ; Family Planning Services/statistics & numerical data ; Female ; Follow-Up Studies ; Humans ; Infertility, Female/prevention & control ; Intention ; Kidney Transplantation/methods ; Kidney Transplantation/psychology ; Liver Transplantation/methods ; Liver Transplantation/psychology ; Middle Aged ; Patient-Centered Care ; Pregnancy ; Reproductive Behavior/psychology ; Surveys and Questionnaires ; Young Adult
Language	English
Publishing date	2018-09-17
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	639001-8
ISSN	1399-0012 ; 0902-0063
ISSN (online)	1399-0012
ISSN	0902-0063
DOI	10.1111/ctr.13378
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Article ; Online: Contraceptive awareness and birth control selection in female kidney and liver transplant recipients.

Szpotanska-Sikorska, Monika / Pietrzak, Bronislawa / Wielgos, Miroslaw

Contraception

2014 Volume 90, Issue 4, Page(s) 435–439

Abstract: Objective(s): Interest has increased regarding the issue of contraception in transplant recipients. The purpose of this study was to assess birth control selection and the role of contraceptive counseling sessions in female kidney transplant (KT) and ... ...

Abstract	Objective(s): Interest has increased regarding the issue of contraception in transplant recipients. The purpose of this study was to assess birth control selection and the role of contraceptive counseling sessions in female kidney transplant (KT) and liver transplant (LT) recipients. Study design: A cross-sectional single-center survey study of 217 female organ recipients (KT, 137 and LT, 80), aged 18-45 years, met the study criteria. Patients were asked 43 questions regarding their pre- and posttransplantation use of contraceptive methods, birth control awareness, contraception counseling and the factors determining the selection of effective contraception (hormonal contraception, intrauterine devices and female sterilization). Results: Thirty-three percent (5/15) of patients who had undergone the transplantation within 1 year prior to study inclusion were unaware of the necessity to use contraception. Both of the groups studied did not differ significantly in terms of the rates of pre- and posttransplantation consultations on effective contraception (KT: 26% vs. 34%; p=0.153 and LT 38% vs. 35%; p=0.729). Effective posttransplantation contraception was used by one in three patients, as indicated by posttransplantation consultations (KT: 30% vs. LT: 29%; p=0.910). The following factors affected the posttransplantation use of effective contraception: the presence of posttransplantation counseling on effective contraception [odds ratio (OR): 6.67; 95% confidence interval (CI): 2.12-20.1] and infrequent sexual activity prior to transplantation (OR: 0.56; 95% CI: 0.35-0.89). Conclusion(s): The selection of effective contraception in KT and LT recipients remain suboptimal. Despite the low numbers of women who received contraceptive counseling in this study, consultation was nonetheless associated with choosing an effective method of contraception. Implication: Current literature and data regarding contraception among female organ transplant recipients remain limited and are predominantly limited to a single population. The purpose of the study was to assess the level of satisfaction and the reasons underlying birth control selection in female kidney and LT recipients.
MeSH term(s)	Adolescent ; Adult ; Condoms ; Contraception Behavior ; Contraceptive Agents, Female ; Cross-Sectional Studies ; Directive Counseling ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Intrauterine Devices ; Kidney Transplantation/psychology ; Liver Transplantation/psychology ; Middle Aged ; Postoperative Period ; Sexual Behavior ; Sterilization, Tubal ; Young Adult
Chemical Substances	Contraceptive Agents, Female
Language	English
Publishing date	2014-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	80106-9
ISSN	1879-0518 ; 0010-7824
ISSN (online)	1879-0518
ISSN	0010-7824
DOI	10.1016/j.contraception.2014.04.014
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