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  1. Book: Bacteriophage therapy

    Azeredo, Joana / Sillankorva, Sanna

    from lab to clinical practice

    (Methods in molecular biology ; 1693 ; Springer protocols)

    2018  

    Author's details edited by Joana Azeredo, Sanna Sillankorva
    Series title Methods in molecular biology ; 1693
    Springer protocols
    Collection
    Keywords Bacteriophages ; fastidious bacteria ; anaerobic bacteria ; biofilm ; Synthetic biology
    Subject code 570
    Language English
    Size xi, 303 Seiten, Illustrationen, Diagramme, 25.4 cm x 17.8 cm
    Publisher Humana Press
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT019552997
    ISBN 978-1-4939-7394-1 ; 1-4939-7394-0 ; 9781493973958 ; 1493973959
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 7042 -1693- verfügbar in Königswinter Königswinter

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  2. Book ; Online: Antibiotic Alternatives and Combinational Therapies for Bacterial Infections

    Sillankorva, Sanna / Olívia Pereira, Maria / Henriques, Mariana

    2019  

    Keywords Science: general issues ; Medical microbiology & virology ; Microbiology (non-medical) ; Antibacterial ; Bacteriophages ; Probiotics ; antibiotic resistance ; Antibiofilm ; antibiotic derivatives
    Size 1 electronic resource (222 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230540
    ISBN 9782889457892 ; 2889457893
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Isolation of Bacteriophages for Clinically Relevant Bacteria.

    Sillankorva, Sanna / Hyman, Paul

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2734, Page(s) 3–12

    Abstract: The isolation of bacteriophages targeting most clinically relevant bacteria is reasonably straightforward as long as its targeted host does not have complex chemical, physical, and environmental requirements. Often, sewage, soil, feces, and different ... ...

    Abstract The isolation of bacteriophages targeting most clinically relevant bacteria is reasonably straightforward as long as its targeted host does not have complex chemical, physical, and environmental requirements. Often, sewage, soil, feces, and different body fluids are used for bacteriophage isolation procedures, and following enrichment, it is common to obtain more than a single phage in a sample. This chapter describes a simple method for the enrichment and isolation of bacteriophages from liquid and solid samples that can be adapted for different clinically important aerobic bacteria.
    MeSH term(s) Bacteriophages ; Bacteria ; Sewage ; Feces ; Soil
    Chemical Substances Sewage ; Soil
    Language English
    Publishing date 2023-12-08
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3523-0_1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Polymeric Microneedles for Health Care Monitoring: An Emerging Trend.

    Pereira, Raquel L / Vinayakumar, K B / Sillankorva, Sanna

    ACS sensors

    2024  

    Abstract: Bioanalyte collection by blood draw is a painful process, prone to needle phobia and injuries. Microneedles can be engineered to penetrate the epidermal skin barrier and collect analytes from the interstitial fluid, arising as a safe, painless, and ... ...

    Abstract Bioanalyte collection by blood draw is a painful process, prone to needle phobia and injuries. Microneedles can be engineered to penetrate the epidermal skin barrier and collect analytes from the interstitial fluid, arising as a safe, painless, and effective alternative to hypodermic needles. Although there are plenty of reviews on the various types of microneedles and their use as drug delivery systems, there is a lack of systematization on the application of polymeric microneedles for diagnosis. In this review, we focus on the current state of the art of this field, while providing information on safety, preclinical and clinical trials, and market distribution, to outline what we believe will be the future of health monitoring.
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2379-3694
    ISSN (online) 2379-3694
    DOI 10.1021/acssensors.4c00612
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Bacteriophage Control of Infectious Biofilms.

    Meneses, Luciana / Sillankorva, Sanna / Azeredo, Joana

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2734, Page(s) 141–150

    Abstract: Biofilm formation, a strategy of bacterial survival, is a significant concern in different areas, including health, where infectious biofilms are very difficult to combat with conventional antimicrobial therapies. Bacteriophages, the viruses that infect ... ...

    Abstract Biofilm formation, a strategy of bacterial survival, is a significant concern in different areas, including health, where infectious biofilms are very difficult to combat with conventional antimicrobial therapies. Bacteriophages, the viruses that infect bacteria, are promising agents to prevent and control biofilm-related infections. This chapter describes a series of standard procedures that can be used to study the potential of bacteriophages for biofilm control, from biofilm formation to bacteriophage treatment and evaluation of its efficacy.
    MeSH term(s) Bacteriophages ; Biofilms ; Anti-Bacterial Agents ; Bacteria
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-12-08
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3523-0_9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Isolation of Bacteriophages for Clinically Relevant Bacteria.

    Sillankorva, Sanna

    Methods in molecular biology (Clifton, N.J.)

    2017  Volume 1693, Page(s) 23–30

    Abstract: A number of bacteriophages deposited in different culture collections target clinically relevant bacterial hosts. In this chapter, we describe a method for isolating bacteriophage plaques for the most common bacteria involved in nosocomial infections. ...

    Abstract A number of bacteriophages deposited in different culture collections target clinically relevant bacterial hosts. In this chapter, we describe a method for isolating bacteriophage plaques for the most common bacteria involved in nosocomial infections.
    MeSH term(s) Bacteria/classification ; Bacteria/virology ; Bacteriophages/isolation & purification ; Cross Infection/microbiology ; Host Specificity ; Humans
    Language English
    Publishing date 2017-11-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-4939-7395-8_3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Designing an antimicrobial film for wound applications incorporating bacteriophages and ε-poly-l-lysine.

    Pinto, Ana M / Pereira, Raquel / Martins, Artur J / Pastrana, Lorenzo M / Cerqueira, Miguel A / Sillankorva, Sanna

    International journal of biological macromolecules

    2024  Volume 268, Issue Pt 2, Page(s) 131963

    Abstract: Alginate-based dressings have been shown to promote wound healing, leveraging the unique properties of alginate. This work aimed to develop and characterize flexible individual and bilayered films to deliver bacteriophages (phages) and ε-Poly-l-lysine (ε- ...

    Abstract Alginate-based dressings have been shown to promote wound healing, leveraging the unique properties of alginate. This work aimed to develop and characterize flexible individual and bilayered films to deliver bacteriophages (phages) and ε-Poly-l-lysine (ε-PLL). Films varied in different properties. The moisture content, swelling and solubility increased with higher alginate concentrations. The water vapour permeability, crucial in biomedical films to balance moisture levels for effective wound healing, reached optimal levels in bilayer films, indicating these will be able to sustain an ideal moist environment. The bilayer films showed improved ductility (lower tensile strength and increased elongation at break) compared to individual films. The incorporated phages maintained viability for 12 weeks under vacuum and refrigerated conditions, and their release was sustained and gradual. Antibacterial immersion tests showed that films with phages and ε-PLL significantly inhibited Pseudomonas aeruginosa PAO1 growth (>3.1 Log CFU/cm
    Language English
    Publishing date 2024-04-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.131963
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2374: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Antibiofilm Efficacy of the Pseudomonas aeruginosa Pbunavirus vB_PaeM-SMS29 Loaded onto Dissolving Polyvinyl Alcohol Microneedles

    Sillankorva, Sanna / Pires, Liliana / Pastrana, Lorenzo M / Bañobre-López, Manuel

    Viruses

    2022  Volume 14, Issue 5

    Abstract: Resistant bacteria prevail in most chronic skin wounds and other biofilm-related topical skin infections. Bacteriophages (phages) have proven their antimicrobial effectiveness for treating different antibiotic-resistant and multidrug-resistant bacterial ... ...

    Abstract Resistant bacteria prevail in most chronic skin wounds and other biofilm-related topical skin infections. Bacteriophages (phages) have proven their antimicrobial effectiveness for treating different antibiotic-resistant and multidrug-resistant bacterial infections, but not all phages are effective against biofilms. Phages possessing depolymerases can reach different biofilm layers; however, those that do not have depolymerase activity struggle to penetrate and navigate in the intricate 3D biofilm structure and mainly infect bacteria lodged in the outer biofilm layers. To address this,
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Bacteriophages ; Biofilms ; Myoviridae ; Polyvinyl Alcohol/pharmacology ; Pseudomonas aeruginosa
    Chemical Substances Anti-Bacterial Agents ; Polyvinyl Alcohol (9002-89-5)
    Language English
    Publishing date 2022-05-05
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14050964
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Bacteriophage Delivery Systems for Food Applications: Opportunities and Perspectives.

    Costa, Maria J / Pastrana, Lorenzo M / Teixeira, José A / Sillankorva, Sanna M / Cerqueira, Miguel A

    Viruses

    2023  Volume 15, Issue 6

    Abstract: Currently, one-third of all food produced worldwide is wasted or lost, and bacterial contamination is one of the main reasons. Moreover, foodborne diseases are a severe problem, causing more than 420,000 deaths and nearly 600 million illnesses yearly, ... ...

    Abstract Currently, one-third of all food produced worldwide is wasted or lost, and bacterial contamination is one of the main reasons. Moreover, foodborne diseases are a severe problem, causing more than 420,000 deaths and nearly 600 million illnesses yearly, demanding more attention to food safety. Thus, new solutions need to be explored to tackle these problems. A possible solution for bacterial contamination is using bacteriophages (phages), which are harmless to humans; these natural viruses can be used to prevent or reduce food contamination by foodborne pathogens. In this regard, several studies showed the effectiveness of phages against bacteria. However, when used in their free form, phages can lose infectivity, decreasing the application in foods. To overcome this problem, new delivery systems are being studied to incorporate phages and ensure prolonged activity and controlled release in food systems. This review focuses on the existent and new phage delivery systems applied in the food industry to promote food safety. Initially, an overview of phages, their main advantages, and challenges is presented, followed by the different delivery systems, focused in methodologies, and biomaterials that can be used. In the end, examples of phage applications in foods are disclosed and future perspectives are approached.
    MeSH term(s) Humans ; Bacteriophages ; Food Contamination/prevention & control ; Food Safety/methods ; Foodborne Diseases/prevention & control ; Foodborne Diseases/microbiology ; Bacteria
    Language English
    Publishing date 2023-05-29
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15061271
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Editorial: Phage-bacteria interplay: Future therapeutic approaches against antibiotic resistant bacteria.

    Silva-Valenzuela, Cecilia A / Molina-Quiroz, Roberto C / Sillankorva, Sanna

    Frontiers in cellular and infection microbiology

    2022  Volume 12, Page(s) 1124187

    MeSH term(s) Bacteriophages ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Bacteria ; Phage Therapy
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-12-30
    Publishing country Switzerland
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2022.1124187
    Database MEDical Literature Analysis and Retrieval System OnLINE

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