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  1. Article ; Online: Diagnosis and management of post-tuberculosis lung disease.

    Silva, Denise Rossato / Mello, Fernanda Carvalho de Queiroz / Migliori, Giovanni Battista

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2023  Volume 49, Issue 2, Page(s) e20230055

    MeSH term(s) Humans ; Lung Diseases/diagnosis ; Tuberculosis ; Lung
    Language Portuguese
    Publishing date 2023-05-15
    Publishing country Brazil
    Document type Editorial
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20230055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effect of vaccination on COVID-19 hospitalizations and mortality.

    Dantas Filho, Fábio Fernandes / D'Ávila, Karen Gomes / Silva, Denise Rossato

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2023  Volume 49, Issue 4, Page(s) e20230254

    MeSH term(s) Humans ; COVID-19/prevention & control ; Vaccination
    Language Portuguese
    Publishing date 2023-09-18
    Publishing country Brazil
    Document type Editorial
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20230254
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  3. Article ; Online: Severe acute respiratory syndrome coronavirus 2 seroprevalence among patients with pulmonary tuberculosis.

    Dias, Natan José Dutra / Silva, Maiana Silva da / Barbosa, Márcia Silva / Pereira, Giovana Rodrigues / Silva, Denise Rossato

    Revista da Associacao Medica Brasileira (1992)

    2023  Volume 69, Issue 9, Page(s) e20230661

    Abstract: Objective: The objective of this study was to estimate the seroprevalence of severe acute respiratory syndrome coronavirus 2 antibodies in patients with tuberculosis.: Methods: This cross-sectional study was conducted at an outpatient tuberculosis ... ...

    Abstract Objective: The objective of this study was to estimate the seroprevalence of severe acute respiratory syndrome coronavirus 2 antibodies in patients with tuberculosis.
    Methods: This cross-sectional study was conducted at an outpatient tuberculosis clinic in Alvorada, RS, Brazil, with data collection between October and December 2020. Outpatients aged>18 years with active pulmonary tuberculosis, no prior history of coronavirus disease 2019, and no suspected coronavirus disease 2019 were included in the study. Whole blood samples were collected to perform the severe acute respiratory syndrome coronavirus 2 antibodies test.
    Results: During the study period, 52 patients met the inclusion and were included in the analysis. Severe acute respiratory syndrome coronavirus 2 antibodies were positive in 16 (30.8%) patients. Male sex was more frequent among patients with negative severe acute respiratory syndrome coronavirus 2 antibodies than in patients with positive severe acute respiratory syndrome coronavirus 2 antibodies (86.1 vs. 56.3%, p=0.031). Contact with coronavirus disease 2019 case was more common in patients with positive severe acute respiratory syndrome coronavirus 2 antibodies compared with patients with negative severe acute respiratory syndrome coronavirus 2 antibodies (87.5 vs. 8.3%, p<0.0001). In a multivariate analysis, in a model including the variables such as male sex and contact with coronavirus disease 2019 case, only contact with coronavirus disease 2019 was independently associated with positive severe acute respiratory syndrome coronavirus 2 antibodies (OR 77.0, 95%CI 11.5-512.4, p<0.0001).
    Conclusion: This study revealed a seroprevalence of 30.8% severe acute respiratory syndrome coronavirus 2 among patients with tuberculosis.
    MeSH term(s) Humans ; Male ; SARS-CoV-2 ; Cross-Sectional Studies ; Seroepidemiologic Studies ; COVID-19/epidemiology ; Tuberculosis, Pulmonary/epidemiology ; Outpatients
    Language English
    Publishing date 2023-09-18
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 731969-1
    ISSN 1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X
    ISSN (online) 1806-9282
    ISSN 0104-4230 ; 0004-5241 ; 0102-843X
    DOI 10.1590/1806-9282.20230661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 654: Show issues Location:
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  4. Article ; Online: Audience response system smartphone application as an adjunct to tuberculosis teaching for medical students during the coronavirus disease 2019 pandemic.

    Cabral, Vagner Kunz / Cionek, Otávio Augusto Gonçalves Dias / Loureiro, Marcelle Martinez / Simbine, Rosa Elisa Bernardo / Silva, Denise Rossato

    Revista da Associacao Medica Brasileira (1992)

    2023  Volume 70, Issue 1, Page(s) e20231132

    Abstract: Objective: The growing availability of devices for mobile learning has created new opportunities for teaching. With the development of smartphone apps based on audience response systems, there is a possibility to quickly assess student knowledge. The ... ...

    Abstract Objective: The growing availability of devices for mobile learning has created new opportunities for teaching. With the development of smartphone apps based on audience response systems, there is a possibility to quickly assess student knowledge. The education of health professionals, including medical students, is an essential strategy for tuberculosis control. In the context of the coronavirus disease 2019 pandemic, audience response systems are very useful as online assessment tools. The aim of this study was to use the audience response systems Socrative to assess medical students during a class on tuberculosis.
    Methods: This is a quasi-experimental before-and-after study, with pre- and post-tests carried out through the Socrative app, respectively, before and after a lecture on tuberculosis for medical students. Also, a cross-sectional study was carried out after the course to evaluate the participant's satisfaction through an electronic, structured questionnaire with a Likert-type scale.
    Results: A total of 126 students were included in the study. The overall mean pre- and post-test scores were 5.98±1.59 and 8.37±1.36, respectively, with a statistically significant difference (p<0.0001). Almost all students were totally satisfied with the use of Socrative on pre- and post-tests.
    Conclusion: This study describes how the use of Socrative in a tuberculosis class was well received by students. In addition, the baseline knowledge on tuberculosis was low in some topics, with some improvement after the lecture. These findings emphasize the need to further improve the students' knowledge on tuberculosis and help instructors customize the lecture based on the gaps identified in the Socrative assessment.
    MeSH term(s) Humans ; Mobile Applications ; Students, Medical ; Smartphone ; Cross-Sectional Studies ; Pandemics ; Educational Measurement ; COVID-19 ; Tuberculosis
    Language English
    Publishing date 2023-12-18
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 731969-1
    ISSN 1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X
    ISSN (online) 1806-9282
    ISSN 0104-4230 ; 0004-5241 ; 0102-843X
    DOI 10.1590/1806-9282.20231132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  5. Article ; Online: Effects of COVID-19 on tuberculosis control: past, present, and future.

    Silva, Denise Rossato / Mello, Fernanda Carvalho de Queiroz / Migliori, Giovanni Battista

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2022  Volume 48, Issue 2, Page(s) e20220102

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Tuberculosis/prevention & control
    Language Portuguese
    Publishing date 2022-05-13
    Publishing country Brazil
    Document type Editorial
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20220102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Tuberculosis Series 2021.

    Silva, Denise Rossato / Mello, Fernanda Carvalho de Queiroz / Migliori, Giovanni Battista

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2021  Volume 47, Issue 2, Page(s) e20210109

    MeSH term(s) Antitubercular Agents ; Humans ; Tuberculosis
    Chemical Substances Antitubercular Agents
    Language Portuguese
    Publishing date 2021-04-30
    Publishing country Brazil
    Document type Editorial
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20210109
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Migration and medical screening for tuberculosis.

    Silva, Denise Rossato / Mello, Fernanda Carvalho de Queiroz / Johansen, Fernanda Dockhorn Costa / Centis, Rosella / D'Ambrosio, Lia / Migliori, Giovanni Battista

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2023  Volume 49, Issue 2, Page(s) e20230051

    Abstract: Vulnerable populations, such as migrants and refugees, have an increased risk of tuberculosis disease, especially in the first years after arrival in the host country. The presence of migrants and refugees in Brazil exponentially grew over the period ... ...

    Abstract Vulnerable populations, such as migrants and refugees, have an increased risk of tuberculosis disease, especially in the first years after arrival in the host country. The presence of migrants and refugees in Brazil exponentially grew over the period between 2011 and 2020, and approximately 1.3 million migrants from the Global South were estimated to be residing in Brazil, most of whom from Venezuela and Haiti. Tuberculosis control programs for migrants can be divided into pre- and post-migration screening strategies. Pre-migration screening aims to identify cases of tuberculosis infection (TBI) and can be carried out in the country of origin (pre-entry) or in the destination country (at entry). Pre-migration screening can also detect migrants at an increased risk of developing tuberculosis in the future. High-risk migrants are then followed up in post-migration screening. In Brazil, migrants are considered a priority group for the active search for tuberculosis cases. However, there is no recommendation or plan regarding screening for TBI in migrants and refugees. Ensuring prevention, diagnosis, and treatment for TBI and tuberculosis disease in migrant populations is an important aspect of tuberculosis control and elimination. In this review article, we address epidemiological aspects and access to health care for migrants in Brazil. In addition, the migration medical screening for tuberculosis was reviewed.
    MeSH term(s) Humans ; Mass Screening/methods ; Incidence ; Tuberculosis/diagnosis ; Tuberculosis/epidemiology ; Tuberculosis/prevention & control ; Latent Tuberculosis/diagnosis ; Latent Tuberculosis/epidemiology ; Transients and Migrants
    Language Portuguese
    Publishing date 2023-04-28
    Publishing country Brazil
    Document type Review ; Journal Article
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20230051
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  8. Article ; Online: Impact of COVID-19 pandemic on tuberculosis and latent tuberculosis infection diagnosis in healthcare workers.

    Rott Monaiar, Luciana / Gomes D'Avila, Karen / Soccol, Emanuelle Bianchi / Santos, André Kulzer / Lima de Braga, Raimunda Sinthia / Fernandes Dantas Filho, Fábio / Silva, Denise Rossato

    Journal of occupational and environmental medicine

    2024  

    Abstract: Objectives: To compare the prevalence of LTBI and TB in the pre-pandemic period (2017-2019) with the pandemic period (2020-2022), in a group of HCW.: Methods: Retrospective study. Data on TB diagnosis was retrieved from the hospital information ... ...

    Abstract Objectives: To compare the prevalence of LTBI and TB in the pre-pandemic period (2017-2019) with the pandemic period (2020-2022), in a group of HCW.
    Methods: Retrospective study. Data on TB diagnosis was retrieved from the hospital information system database. All HCWs who underwent tuberculin skin test (TST) from January 2017 to December 2022 were included in the study.
    Results: In the pre-pandemic period (2017-2019), 163 HCW out of 710 were TST positive (22.9%), and in the pandemic period (2020-2022), 85 HCW out of 449 were TST positive (18.9%) (p = 0.11). There were 10 HCW diagnosed with TB in the pre-pandemic period (incidence: 41.7/100,000) and 2 in the pandemic period (incidence: 8.3/100,000) (p < 0.0001).
    Conclusions: This study showed that TB incidence was reduced during the pandemic period in HCW. TST positivity was also reduced, although not statistically significant.
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1223932-x
    ISSN 1536-5948 ; 1076-2752
    ISSN (online) 1536-5948
    ISSN 1076-2752
    DOI 10.1097/JOM.0000000000003127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 155: Show issues Location:
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  9. Article ; Online: Tuberculosis series 2020.

    Silva, Denise Rossato / Mello, Fernanda Carvalho de Queiroz / Migliori, Giovanni Battista

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2020  Volume 46, Issue 2, Page(s) e20200027

    MeSH term(s) Antitubercular Agents/therapeutic use ; Humans ; Tuberculosis/diagnosis ; Tuberculosis/drug therapy
    Chemical Substances Antitubercular Agents
    Language Portuguese
    Publishing date 2020-03-02
    Publishing country Brazil
    Document type Editorial
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20200027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Shortened tuberculosis treatment regimens: what is new?

    Silva, Denise Rossato / Mello, Fernanda Carvalho de Queiroz / Migliori, Giovanni Battista

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2020  Volume 46, Issue 2, Page(s) e20200009

    Abstract: Given the global burden of tuberculosis, shortened treatment regimens with existing or repurposed drugs are needed to contribute to tuberculosis control. The long duration of treatment of drug-susceptible tuberculosis (DS-TB) is associated with ... ...

    Abstract Given the global burden of tuberculosis, shortened treatment regimens with existing or repurposed drugs are needed to contribute to tuberculosis control. The long duration of treatment of drug-susceptible tuberculosis (DS-TB) is associated with nonadherence and loss to follow up, and the treatment success rate of multidrug-resistant tuberculosis (MDR-TB) is low (approximately 50%) with longer regimens. In this review article, we report recent advances and ongoing clinical trials aimed at shortening regimens for DS-TB and MDR-TB. We discuss the role of high-dose rifampin, as well as that of clofazimine and linezolid in regimens for DS-TB. There are at least 5 ongoing clinical trials and 17 observational studies and clinical trials evaluating shorter regimens for DS-TB and MDR-TB, respectively. We also report the results of observational studies and clinical trials evaluating a standardized nine-month moxifloxacin-based regimen for MDR-TB. Further studies, especially randomized clinical trials, are needed to evaluate regimens including newer drugs, drugs proven to be or highly likely to be efficacious, and all-oral drugs in an effort to eliminate the need for injectable drugs.
    MeSH term(s) Antitubercular Agents/therapeutic use ; Clinical Protocols ; Clinical Trials as Topic ; Clofazimine/therapeutic use ; Humans ; Linezolid/therapeutic use ; Rifampin/therapeutic use ; Tuberculosis/drug therapy ; Tuberculosis, Multidrug-Resistant/drug therapy
    Chemical Substances Antitubercular Agents ; Clofazimine (D959AE5USF) ; Linezolid (ISQ9I6J12J) ; Rifampin (VJT6J7R4TR)
    Language Portuguese
    Publishing date 2020-03-23
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20200009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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