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  1. Book: Cancer epidemiology

    Silva, Isabel dos Santos

    principles and methods

    1999  

    Author's details by Isabel dos Santos Silva
    Keywords Neoplasms / epidemiology ; Epidemiologic Methods ; Krebs ; Epidemiologie
    Subject Krankheitsverbreitung ; Carcinom ; Malignom ; Maligner Tumor ; Neoplasma ; Karzinom ; Bösartiger Tumor ; Krebserkrankung
    Language English
    Size X, 442 S. : Ill., graph. Darst., Kt.
    Edition 2. ed.
    Publisher Internat. Agency for Research on Cancer
    Publishing place Lyon
    Publishing country France
    Document type Book
    HBZ-ID HT013079397
    ISBN 92-832-0405-0 ; 978-92-832-0405-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2001 A 3537 order for loan Magazin

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  2. Book: Cancer incidence and mortality in England and Wales

    Swerdlow, Anthony / Silva, Isabel dos Santos / Doll, Richard

    trends and risk factors

    2001  

    Author's details Anthony Swerdlow, Isabel dos Santos Silva and Richard Doll
    Language English
    Size X, 290 S. : graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT012970240
    ISBN 0-19-262748-1 ; 978-0-19-262748-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2001 A 1883 order for loan Magazin

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  3. Book: Atlas of cancer incidence in England and Wales 1968-85

    Swerdlow, Anthony / Silva, Isabel dos Santos

    (based on data from the cancer registries of England and Wales)

    1993  

    Author's details Anthony Swerdlow and Isabel dos Santos Silva
    Keywords Neoplasms / epidemiology / England / maps ; Neoplasms / epidemiology / Wales / maps ; Neoplasms / epidemiology / England / statistics ; Neoplasms / epidemiology / Wales / statistics ; Wales ; Krebs ; Atlas ; England
    Subject Weltatlas ; Bildatlas ; Topographischer Atlas ; Topografischer Atlas ; Atlanten ; Carcinom ; Malignom ; Maligner Tumor ; Neoplasma ; Karzinom ; Bösartiger Tumor ; Krebserkrankung
    Language English
    Size XIX, 275 S. : zahlr. Kt.
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT006420871
    ISBN 0-19-261993-4 ; 978-0-19-261993-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1994 A 4340 order for loan Magazin

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  4. Book ; Online: Epidemiología del Cáncer

    Silva, Isabel dos Santos

    US1.1

    Principios y métodos

    2013  

    Keywords PALTEX
    Language Spanish
    Publishing date 2013-11-19T20:37:59Z
    Publisher OPS
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  5. Book ; Online: Epidemiología del Cáncer

    Silva, Isabel dos Santos

    Principios y métodos

    2013  

    Keywords PALTEX
    Language Spanish
    Publishing date 2013-11-19T20:37:59Z
    Publisher OPS
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article: Oral microbiome and risk of malignant esophageal lesions in a high-risk area of China: A nested case-control study.

    Liu, Fangfang / Liu, Mengfei / Liu, Ying / Guo, Chuanhai / Zhou, Yunlai / Li, Fenglei / Xu, Ruiping / Liu, Zhen / Deng, Qiuju / Li, Xiang / Zhang, Chaoting / Pan, Yaqi / Ning, Tao / Dong, Xiao / Hu, Zhe / Bao, Huanyu / Cai, Hong / Silva, Isabel Dos Santos / He, Zhonghu /
    Ke, Yang

    Chinese journal of cancer research = Chung-kuo yen cheng yen chiu

    2021  Volume 32, Issue 6, Page(s) 742–754

    Abstract: Objective: We aimed to prospectively evaluate the association of oral microbiome with malignant esophageal lesions and its predictive potential as a biomarker of risk.: Methods: We conducted a case-control study nested within a population-based ... ...

    Abstract Objective: We aimed to prospectively evaluate the association of oral microbiome with malignant esophageal lesions and its predictive potential as a biomarker of risk.
    Methods: We conducted a case-control study nested within a population-based cohort with up to 8 visits of oral swab collection for each subject over an 11-year period in a high-risk area for esophageal cancer in China. The oral microbiome was evaluated with 16S ribosomal RNA (rRNA) gene sequencing in 428 pre-diagnostic oral specimens from 84 cases with esophageal lesions of severe squamous dysplasia and above (SDA) and 168 matched healthy controls. DESeq analysis was performed to identify taxa of differential abundance. Differential oral species together with subject characteristics were evaluated for their potential in predicting SDA risk by constructing conditional logistic regression models.
    Results: A total of 125 taxa including 37 named species showed significantly different abundance between SDA cases and controls (all P<0.05 & false discovery rate-adjusted Q<0.10). A multivariate logistic model including 11 SDA lesion-related species and family history of esophageal cancer provided an area under the receiver operating characteristic curve (AUC) of 0.89 (95% CI, 0.84-0.93). Cross-validation and sensitivity analysis, excluding cases diagnosed within 1 year of collection of the baseline specimen and their matched controls, or restriction to screen-endoscopic-detected or clinically diagnosed case-control triads, or using only bacterial data measured at the baseline, yielded AUCs>0.84.
    Conclusions: The oral microbiome may play an etiological and predictive role in esophageal cancer, and it holds promise as a non-invasive early warning biomarker for risk stratification for esophageal cancer screening programs.
    Language English
    Publishing date 2021-01-14
    Publishing country China
    Document type Journal Article
    ZDB-ID 1067584-x
    ISSN 1993-0631 ; 1000-9604
    ISSN (online) 1993-0631
    ISSN 1000-9604
    DOI 10.21147/j.issn.1000-9604.2020.06.07
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3157: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Book: A dictionary of epidemiology

    Porta, Miquel S / Greenland, Sander / Hernán, Miguel / Silva, Isabel dos Santos / Last, John M

    2014  

    Institution International Epidemiological Association,
    MeSH term(s) Epidemiology
    Language English
    Size xxxii, 343 pages :, illustrations
    Edition Six edition /
    Document type Book
    Note "A handbook sponsored by the IEA"--Cover.
    ISBN 9780199976720 ; 9780199976737 ; 0199976724 ; 0199976732
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Article ; Online: Breast MRI segmentation for density estimation: Do different methods give the same results and how much do differences matter?

    Doran, Simon J / Hipwell, John H / Denholm, Rachel / Eiben, Björn / Busana, Marta / Hawkes, David J / Leach, Martin O / Silva, Isabel Dos Santos

    Medical physics

    2017  Volume 44, Issue 9, Page(s) 4573–4592

    Abstract: Purpose: To compare two methods of automatic breast segmentation with each other and with manual segmentation in a large subject cohort. To discuss the factors involved in selecting the most appropriate algorithm for automatic segmentation and, in ... ...

    Abstract Purpose: To compare two methods of automatic breast segmentation with each other and with manual segmentation in a large subject cohort. To discuss the factors involved in selecting the most appropriate algorithm for automatic segmentation and, in particular, to investigate the appropriateness of overlap measures (e.g., Dice and Jaccard coefficients) as the primary determinant in algorithm selection.
    Methods: Two methods of breast segmentation were applied to the task of calculating MRI breast density in 200 subjects drawn from the Avon Longitudinal Study of Parents and Children, a large cohort study with an MRI component. A semiautomated, bias-corrected, fuzzy C-means (BC-FCM) method was combined with morphological operations to segment the overall breast volume from in-phase Dixon images. The method makes use of novel, problem-specific insights. The resulting segmentation mask was then applied to the corresponding Dixon water and fat images, which were combined to give Dixon MRI density values. Contemporaneously acquired T
    Results: Images are presented for two individual women, demonstrating how the difficulty of the problem is highly subject-specific. Dice and Jaccard coefficients comparing the semiautomated BC-FCM method, operating on Dixon source data, with expert manual segmentation are presented. The corresponding results for the method based on T
    Conclusions: Epidemiological results demonstrate that both methods of automated segmentation are suitable for the chosen application and that it is important to consider a range of factors when choosing a segmentation algorithm, rather than focus narrowly on a single metric such as the Dice coefficient.
    MeSH term(s) Algorithms ; Breast/diagnostic imaging ; Female ; Humans ; Longitudinal Studies ; Magnetic Resonance Imaging ; Radiography
    Language English
    Publishing date 2017-07-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 188780-4
    ISSN 2473-4209 ; 0094-2405
    ISSN (online) 2473-4209
    ISSN 0094-2405
    DOI 10.1002/mp.12320
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1210: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Dietary intake and nutritional adequacy prior to conception and during pregnancy: a follow-up study in the north of Portugal

    Pinto, Elisabete / Barros, Henrique / Silva, Isabel dos Santos

    Public health nutrition. 2009 July, v. 12, no. 7

    2009  

    Keywords diet ; food intake ; conception ; nutritional adequacy ; pregnancy ; women ; pregnant women ; longitudinal studies ; energy intake ; nutrient intake ; vitamin E ; vitamin A ; riboflavin ; folic acid ; dietary minerals ; calcium ; magnesium ; alcoholic beverages ; caffeine ; dietary supplements ; iron ; Portugal
    Language English
    Dates of publication 2009-07
    Size p. 922-931.
    Document type Article
    ZDB-ID 1436024-x
    ISSN 1475-2727 ; 1368-9800
    ISSN (online) 1475-2727
    ISSN 1368-9800
    DOI 10.1017/S1368980008003595
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 6998: Show issues

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  10. Article ; Online: Epidemiología del cáncer

    Silva Isabel dos Santos

    Revista Española de Salud Pública, Vol 74, Iss 2, Pp 00-

    principios y métodos

    2000  Volume 00

    Keywords Medicine ; R ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2000-01-01T00:00:00Z
    Publisher Ministerio de Sanidad y Consumo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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