Article ; Online: Malformations of the craniocervical junction (Chiari type I and syringomyelia: classification, diagnosis and treatment).
2009 Volume 10 Suppl 1, Page(s) S1
Abstract: Chiari disease (or malformation) is in general a congenital condition characterized by an anatomic defect of the base of the skull, in which the cerebellum and brain stem herniate through the foramen magnum into the cervical spinal canal. The onset of ... ...
| Abstract | Chiari disease (or malformation) is in general a congenital condition characterized by an anatomic defect of the base of the skull, in which the cerebellum and brain stem herniate through the foramen magnum into the cervical spinal canal. The onset of Chiari syndrome symptoms usually occurs in the second or third decade (age 25 to 45 years). Symptoms may vary between periods of exacerbation and remission. The diagnosis of Chiari type I malformation in patients with or without symptoms is established with neuroimaging techniques. The most effective therapy for patients with Chiari type I malformation/syringomyelia is surgical decompression of the foramen magnum, however there are non-surgical therapy to relieve neuropathic pain: either pharmacological and non-pharmacological. Pharmacological therapy use drugs that act on different components of pain. Non-pharmacological therapies are primarily based on spinal or peripheral electrical stimulation. It is important to determine the needs of the patients in terms of health-care, social, educational, occupational, and relationship issues, in addition to those derived from information aspects, particularly at onset of symptoms. Currently, there is no consensus among the specialists regarding the etiology of the disease or how to approach, monitor, follow-up, and treat the condition. It is necessary that the physicians involved in the care of people with this condition comprehensively approach the management and follow-up of the patients, and that they organize interdisciplinary teams including all the professionals that can help to increase the quality of life of patients. |
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| MeSH term(s) | Arnold-Chiari Malformation/classification ; Arnold-Chiari Malformation/complications ; Arnold-Chiari Malformation/diagnosis ; Arnold-Chiari Malformation/psychology ; Arnold-Chiari Malformation/therapy ; Humans ; Syringomyelia/etiology |
| Language | English |
| Publishing date | 2009-12-17 |
| Publishing country | England |
| Document type | Journal Article ; Research Support, Non-U.S. Gov't ; Review |
| ZDB-ID | 2041355-5 |
| ISSN | 1471-2474 ; 1471-2474 |
| ISSN (online) | 1471-2474 |
| ISSN | 1471-2474 |
| DOI | 10.1186/1471-2474-10-S1-S1 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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