LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 3 of total 3

Search options

  1. Article ; Online: A huge infected necrotic submucosal leiomyoma in association with advanced uterovaginal prolapse.

    Lopes-Costa, Pedro Vitor / Andrade, Virginia Araújo / Silva, Rozirene Araujo / da Silva, Benedito Borges

    European journal of obstetrics, gynecology, and reproductive biology

    2018  Volume 223, Page(s) 145–146

    MeSH term(s) Aged ; Female ; Humans ; Leiomyoma/complications ; Leiomyoma/pathology ; Necrosis ; Pelvic Organ Prolapse/complications ; Pelvic Organ Prolapse/pathology ; Uterine Neoplasms/complications ; Uterine Neoplasms/pathology ; Uterus/pathology
    Language English
    Publishing date 2018-02-21
    Publishing country Ireland
    Document type Case Reports ; Letter
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2018.02.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 837: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: CYP19A1 gene expression in the peripheral blood of Brazilian women with breast cancer relapse.

    Barros-Oliveira, Maria da Conceição / Costa-Silva, Danylo Rafhael / Campos-Verdes, Larysse Cardoso / Pereira, Renato de Oliveira / Silva, Rozirene Araújo / Moura-Borges, Paulo de Tarso / Sousa, Emerson Brandão / Pinho-Sobral, André Luiz / Lopes-Costa, Pedro Vitor / Dos Santos, Alesse Ribeiro / Soares-Lopes, Ione Maria Ribeiro / Viana, Jackeline Lopes / Melo, Mariella de Almeida / Manes Neto, Fidelis / Coelho, Eid Gonçalves / Pires E Cruz, Maria do Socorro / Costa-Silva, Vladimir / Gebrim, Luiz Henrique / Da Silva, Benedito Borges

    BMC cancer

    2020  Volume 20, Issue 1, Page(s) 480

    Abstract: Background: The CYP19A1 gene, which encodes the enzyme responsible for androgen aromatization into estrogens, may play an important role in breast cancer aggressiveness. However, no study has evaluated CYP19A1 gene expression in the peripheral blood of ... ...

    Abstract Background: The CYP19A1 gene, which encodes the enzyme responsible for androgen aromatization into estrogens, may play an important role in breast cancer aggressiveness. However, no study has evaluated CYP19A1 gene expression in the peripheral blood of women with relapsed breast cancer.
    Methods: In this cross-sectional study, CYP19A1 gene expression was quantified by RT-PCR in the peripheral blood of 146 women with breast cancer who were first divided into two groups according to the expression of CYP19A1 (low and high); each group had 73 patients. Subsequently, women were divided into two groups: those without recurrence (control, n = 85) and those with recurrence (study, n = 61). Statistical analysis of the data was performed using ANOVA, the Mann-Whitney, Chi-square or Fisher's exact test (p <  0.05).
    Results: There were no significant differences between the relative expression of CYP19A1 mRNA in the low expression group and the high expression group according to the variables studied. There were no significant differences in CYP19A1 gene expression in the study and control groups (p = 0.8461). In the relapse group, CYP19A1 gene expression was significantly higher in the hybrid luminal subtype than in the triple-negative subtype (p = 0.0321), whereas it was significantly lower in HER2-negative cases than in HER2-positive cases (p <  0.0376). Women with locoregional recurrence showed higher expression than women with distant recurrence (p <  0.0001).
    Conclusions: The present study found no significant differences between women with high and low expression of the CYP19A1 gene mRNA or between those in the study group and the control group. However, in women with recurrence, there was increased expression of CYP19A1 mRNA in those who had the luminal hybrid subtype and locoregional relapse and decreased expression in those negative for HER2.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Aromatase/blood ; Aromatase/genetics ; Breast Neoplasms/blood ; Breast Neoplasms/genetics ; Female ; Gene Expression ; Genes, erbB-2 ; Humans ; Middle Aged ; Neoplasm Recurrence, Local/blood ; Neoplasm Recurrence, Local/genetics ; RNA, Messenger/blood ; Reverse Transcriptase Polymerase Chain Reaction
    Chemical Substances RNA, Messenger ; Aromatase (EC 1.14.14.1) ; CYP19A1 protein, human (EC 1.14.14.1)
    Language English
    Publishing date 2020-05-27
    Publishing country England
    Document type Journal Article
    ISSN 1471-2407
    ISSN (online) 1471-2407
    DOI 10.1186/s12885-020-06978-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: A rare case of primary breast angiosarcoma in a male: a case report.

    da Silva, Benedito Borges / Eulálio Filho, Walberto Monteiro Neiva / Costa, Pedro Vitor Lopes / Silva, Rozirene Araújo / Junior, Ariton Mendes Conde / Chagas, Diego Cipriano / de Almeida Melo, Mariella / Neto, Fidelis Manes / Tavares, Cleciton Braga / de Sousa Júnior, Edilson Carvalho / Coelho, Eid Gonçalves / Campelo, Viriato / Gebrim, Luis Henrique / da Silva Junior, Raimundo Gerônimo

    BMC cancer

    2018  Volume 18, Issue 1, Page(s) 978

    Abstract: Background: Sarcomas account for less than 1% of primary breast cancers, and breast angiosarcomas are responsible for only 0.05% of all breast malignancies. The male breast has the same potential for malignant transformation as the female breast. ... ...

    Abstract Background: Sarcomas account for less than 1% of primary breast cancers, and breast angiosarcomas are responsible for only 0.05% of all breast malignancies. The male breast has the same potential for malignant transformation as the female breast. However, due to anatomical differences in the breast and the low incidence of angiosarcoma, it is difficult to determine how male breasts can be affected by this type of tumor.
    Case presentation: A 36-year-old male patient was admitted to the hospital with a palpable lump in his right breast. Lymphadenopathy was negative. Ultrasonography showed a hypoechoic mass with partially defined contours, measuring 4.0 × 3.0 cm, with muscle infiltration. Histological examination revealed a malignant tumor. Radical mastectomy was then performed with clear surgical margins. The patient began chemotherapy with paclitaxel. Following the second cycle of chemotherapy, he presented with headache and seizures due to a frontal lobe metastasis. Twenty days after the onset of neurological symptoms, the patient died.
    Conclusions: Primary angiosarcomas of the male breast are extremely rare. This is the sixth case published in the literature. It is in agreement with other studies in the literature concerning clinical presentation and poor prognosis. Treatment consists in surgical removal of the tumor with clear margins and without axillary lymphadenectomy.
    MeSH term(s) Adult ; Brain Neoplasms/secondary ; Breast Neoplasms, Male/pathology ; Breast Neoplasms, Male/therapy ; Chemotherapy, Adjuvant ; Hemangiosarcoma/pathology ; Hemangiosarcoma/therapy ; Humans ; Male ; Paclitaxel/therapeutic use
    Chemical Substances Paclitaxel (P88XT4IS4D)
    Language English
    Publishing date 2018-10-16
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1471-2407
    ISSN (online) 1471-2407
    DOI 10.1186/s12885-018-4895-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top