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Article ; Online: Normality thresholds for ambulatory blood pressure monitoring (ABPM) in the European, American and Brazilian guidelines: is there a need for revision?

Silva, Ricardo Pereira / Rodrigues, Deyvison Henrique da Silva / Viana Junior, Antônio Brazil / Silva Junior, Geraldo Bezerra da

International journal of cardiology. Cardiovascular risk and prevention

2022 Volume 15, Page(s) 200148

Language	English
Publishing date	2022-08-27
Publishing country	Netherlands
Document type	Journal Article
ISSN	2772-4875
ISSN (online)	2772-4875
DOI	10.1016/j.ijcrp.2022.200148
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Article ; Online: Smartphone and application use in self-management of chronic kidney disease: a cross-sectional feasibility study.

Marinho, Christielle Lidianne Alencar / Gomes, Orlando Vieira / Silva Junior, Geraldo Bezerra da / Schwingel, Paulo Adriano

Sao Paulo medical journal = Revista paulista de medicina

2022 Volume 141, Issue 4, Page(s) e202278

Abstract: Introduction: Smartphone and application use can improve communication and monitoring of chronic diseases, including chronic kidney disease, through self-management and increased adherence to treatment.: Objective: To assess smartphone use in ... ...

Abstract	Introduction: Smartphone and application use can improve communication and monitoring of chronic diseases, including chronic kidney disease, through self-management and increased adherence to treatment. Objective: To assess smartphone use in patients with chronic kidney disease on dialysis and their willingness to use mobile applications as a disease self-management strategy. Design and setting: This was a cross-sectional study of chronic kidney disease patients on hemodialysis in the São Francisco Valley in the Northeast Region, Brazil. Methods: The questionnaire developed by the authors was administered between April and June 2021. Cronbach's alpha coefficient for the construct was 0.69. Associations between the dependent and independent variables were determined using univariate analysis. Multivariate analysis with logistic regression analysis was also performed. Results: A total of 381 patients were included, of whom 64% had a smartphone, although only 3.1% knew of a kidney disease-related application. However, 59.3% believed that using an application could help them manage their disease. Having a smartphone was associated with treatment adherence, higher educational attainment, and higher per capita income. Educational attainment remained an independent factor in multivariate analysis. Conclusion: More than 64% of patients had a smartphone, although few knew of applications developed for kidney disease. More than half of the population believed that technology use could benefit chronic kidney disease treatment. Smartphone ownership was more common among the younger population, with higher educational attainment and income, and was associated with greater adherence to hemodialysis sessions.
MeSH term(s)	Humans ; Smartphone ; Cross-Sectional Studies ; Self-Management ; Feasibility Studies ; Renal Insufficiency, Chronic/therapy
Language	English
Publishing date	2022-10-03
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	1203171-9
ISSN	1806-9460 ; 1516-3180 ; 0035-0362
ISSN (online)	1806-9460
ISSN	1516-3180 ; 0035-0362
DOI	10.1590/1516-3180.2022.0078.R2.09082022
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Article ; Online: Evaluation of the use of a Renal Health application by kidney transplant recipients.

Oliveira, Juliana Gomes Ramalho de / Sanders-Pinheiro, Hélady / Freitas Filho, Ronaldo Almeida de / Vasconcelos Filho, José Eurico / Askari, Marjan / Silva Júnior, Geraldo Bezerra da

Revista latino-americana de enfermagem

2023 Volume 31, Page(s) e3822

Abstract: Objective: to evaluate the use of a renal health application by kidney transplant recipients.: Method: a retrospective, observational study with a sample composed of individuals registered in the kidney transplant section of the application from July ...

Abstract	Objective: to evaluate the use of a renal health application by kidney transplant recipients. Method: a retrospective, observational study with a sample composed of individuals registered in the kidney transplant section of the application from July of 2018 to April of 2021. Demographic data, data entry, time of use, weight, blood pressure, blood glucose, creatinine, medication schedules, appointments, and tests were the variables collected. Descriptive analysis of the data was performed. Results: eight hundred and twenty-three downloads of the application were identified, and 12.3% of those were registered as kidney transplant recipients, the majority from southeastern Brazil (44.9%), 36±11 years old, and female (59.1%). Of the sample, 35.1% entered information such as creatinine (62%), weight (58.2%), and blood pressure (51.8%). Most used the application for one day (63.3%) and 13.9% for more than one hundred days. Those who used it for more than one day (36.7%) recorded weight (69%), medication intake (65.5%) and creatinine (62%), and scheduled appointments (69%). Conclusion: the kidney transplant recipient section of the Renal Health application generated interest in the young population, but showed low adherence throughout the assessed months. These results offer a relevant perspective on the implementation of mHealth technologies in kidney transplantation.
MeSH term(s)	Female ; Humans ; Adult ; Middle Aged ; Kidney Transplantation ; Creatinine ; Retrospective Studies ; Blood Glucose ; Blood Pressure
Chemical Substances	Creatinine (AYI8EX34EU) ; Blood Glucose
Language	Spanish
Publishing date	2023-01-27
Publishing country	Brazil
Document type	Observational Study ; Journal Article
ZDB-ID	2105698-5
ISSN	1518-8345 ; 1518-8345
ISSN (online)	1518-8345
ISSN	1518-8345
DOI	10.1590/1518-8345.6039.3822
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Article ; Online: ELMO CPAP: an innovative type of ventilatory support for COVID-19-related acute respiratory distress syndrome.

Beliero, Andréa Mazza / Lázaro, Ana Paula Pires / Zaranza, Marza de Sousa / Lima, Giovanna Mazza Cruz / Guimarães, Álvaro Rolim / Aragão, Nilcyeli Linhares / Meneses, Gdayllon Cavalcante / Holanda, Marcelo Alcantara / Albuquerque, Polianna Lemos Moura Moreira / Silva Júnior, Geraldo Bezerra da / Fernandes, Paula Frassinetti Castelo Branco Camurça

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

2024 Volume 49, Issue 6, Page(s) e20230227

Abstract: Objective: To assess whether the use of ELMO, a helmet for noninvasive ventilation created in Brazil, had a positive impact on the prognosis of patients with hypoxemic respiratory failure caused by severe COVID-19.: Methods: This is a retrospective ... ...

Abstract	Objective: To assess whether the use of ELMO, a helmet for noninvasive ventilation created in Brazil, had a positive impact on the prognosis of patients with hypoxemic respiratory failure caused by severe COVID-19. Methods: This is a retrospective study of 50 critically ill COVID-19 patients. Epidemiological, clinical, and laboratory data were collected on ICU admission, as well as before, during, and after ELMO use. Patients were divided into two groups (success and failure) according to the outcome. Results: ELMO use improved oxygenation parameters such as Pao2, Fio2, and the Pao2/Fio2 ratio, and this contributed to a gradual reduction in Fio2, without an increase in CO2, as determined by arterial blood gas analysis. Patients in the success group had significantly longer survival (p < 0.001), as determined by the Kaplan-Meier analysis, less need for intubation (p < 0.001), fewer days of hospitalization, and a lower incidence of acute kidney injury in comparison with those in the failure group. Conclusions: The significant improvement in oxygenation parameters, the longer survival, as reflected by the reduced need for intubation and by the mortality rate, and the absence of acute kidney injury suggest that the ELMO CPAP system is a promising tool for treating ARDS and similar clinical conditions.
MeSH term(s)	Humans ; Retrospective Studies ; COVID-19/therapy ; COVID-19/complications ; Respiratory Distress Syndrome/etiology ; Respiratory Distress Syndrome/therapy ; Respiratory Insufficiency/therapy ; Oxygen ; Acute Kidney Injury/complications
Chemical Substances	Oxygen (S88TT14065)
Language	Portuguese
Publishing date	2024-01-15
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2223157-2
ISSN	1806-3756 ; 1806-3713
ISSN (online)	1806-3756
ISSN	1806-3713
DOI	10.36416/1806-3756/e20230227
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Article ; Online: Thrombotic microangiopathy due to Bothrops erythromelas: a case report in Northeast Brazil.

Mota, Sandra Mara Brasileiro / Albuquerque, Polianna Lemos Moura Moreira / Silva Júnior, Geraldo Bezerra da / Daher, Elizabeth De Francesco

Revista do Instituto de Medicina Tropical de Sao Paulo

2020 Volume 62, Page(s) e53

Abstract: Bothrops erythromelas are serpents that belong to the Viperidae family, which are the main species responsible for human snakebites in Ceara State, Northeast Brazil. Thrombotic microangiopathy (TMA) is an uncommon group of disorders characterized by ... ...

Abstract	Bothrops erythromelas are serpents that belong to the Viperidae family, which are the main species responsible for human snakebites in Ceara State, Northeast Brazil. Thrombotic microangiopathy (TMA) is an uncommon group of disorders characterized by microangiopathic hemolytic anemia (MAHA), thrombocytopenia and acute kidney injury (AKI), and occurrence after snakebites have been rarely reported. In this report, we described the case of a 57 year-old-man without comorbidities who was bitten by a Bothrops erythromelas on his right ankle. He presented with pain, edema and local bleeding. Symptomatology and laboratory tests were compatible with the diagnosis of TMA. He received specific antivenom and fluids replacement without any anaphylactic reaction. The conservative treatment was effective and there was no need for red blood cells transfusion or plasmapheresis. The aim of this report was to describe the first case of thrombotic microangiopathy following Bothrops erythromelas envenoming in the Northeast Brazil, providing insights about important mechanistic pathways of Bothrops snakebite-associated TMA and how to change the prognosis of the disease.
MeSH term(s)	Animals ; Antivenins/administration & dosage ; Bothrops ; Brazil ; Humans ; Male ; Middle Aged ; Snake Bites/complications ; Thrombotic Microangiopathies/drug therapy ; Thrombotic Microangiopathies/etiology ; Thrombotic Microangiopathies/pathology ; Treatment Outcome
Chemical Substances	Antivenins
Language	English
Publishing date	2020-07-24
Publishing country	Brazil
Document type	Case Reports ; Journal Article
ZDB-ID	128928-7
ISSN	1678-9946 ; 0036-4665
ISSN (online)	1678-9946
ISSN	0036-4665
DOI	10.1590/s1678-9946202062053
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Article ; Online: Monitoring Renal Function in HIV Patients Without Kidney Disease Using Endothelial Biomarkers: A Prospective Pilot Study.

Cavalcante, Malena Gadelha / Gomes, Pedro Eduardo Andrade de Carvalho / Parente, Matheus de Sá Roriz / Meneses, Gdayllon Cavalcante / Silva Junior, Geraldo Bezerra da / Neto, Roberto da Justa Pires / Martins, Alice Maria Costa / Daher, Elizabeth De Francesco

AIDS research and human retroviruses

2023 Volume 39, Issue 9, Page(s) 468–474

Abstract: This study aimed to investigate the association between novel biomarkers and renal injury in people with HIV (PWH). A cohort study was carried out with PWH under chronic use of antiretroviral therapy (ART), followed at a public outpatient service. ... ...

Abstract	This study aimed to investigate the association between novel biomarkers and renal injury in people with HIV (PWH). A cohort study was carried out with PWH under chronic use of antiretroviral therapy (ART), followed at a public outpatient service. Clinical and laboratory parameters of the patients were evaluated year by year, from 2015 [at baseline (year 1, Y1)] to 2019 [year 5 (Y5)]. At baseline, biomarkers of renal damage (e.g., neutrophil gelatinase-associated lipocalin-NGAL, monocyte chemoattractant protein-1-MCP-1, and kidney injury molecule-1-KIM-1) and endothelial activation or glycocalyx damage [e.g., intercellular adhesion molecule 1 (ICAM-1), E-selectin, and syndecan-1] were quantified using enzyme-linked immunosorbent assays and their levels were used to classify patients into different groups. However, only syndecan-1 showed a significant correlation with serum creatinine (
MeSH term(s)	Humans ; Pilot Projects ; Syndecan-1 ; Cohort Studies ; Prospective Studies ; Creatinine ; HIV Infections/complications ; HIV Infections/drug therapy ; Kidney/physiology ; Kidney Diseases ; Biomarkers ; Glomerular Filtration Rate
Chemical Substances	Syndecan-1 ; Creatinine (AYI8EX34EU) ; Biomarkers
Language	English
Publishing date	2023-04-25
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639130-8
ISSN	1931-8405 ; 0889-2229
ISSN (online)	1931-8405
ISSN	0889-2229
DOI	10.1089/AID.2022.0113
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Article ; Online: Inability to work due to Chikungunya virus infection: impact on public service during the first epidemic in the State of Ceará, northeastern Brazil.

Bastos, Maria Luiza Almeida / Abreu, Francileudo Santos de / Silva Junior, Geraldo Bezerra da

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

2018 Volume 22, Issue 3, Page(s) 248–249

MeSH term(s)	Absenteeism ; Brazil/epidemiology ; Chikungunya Fever/epidemiology ; Employment/statistics & numerical data ; Epidemics ; Humans ; Public Sector
Language	English
Publishing date	2018-05-26
Publishing country	Brazil
Document type	Letter
ZDB-ID	2041400-6
ISSN	1678-4391 ; 1413-8670
ISSN (online)	1678-4391
ISSN	1413-8670
DOI	10.1016/j.bjid.2018.05.002
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Article ; Online: Complications, clinical manifestations of congenital syphilis, and aspects related to its prevention: an integrative review.

Rocha, Ana Fátima Braga / Araújo, Maria Alix Leite / Barros, Valéria Lima de / Américo, Camila Félix / Silva Júnior, Geraldo Bezerra da

Revista brasileira de enfermagem

2021 Volume 74, Issue 4, Page(s) e20190318

Abstract: Objectives: to identify the scientific evidence about the clinical complications and manifestations of congenital syphilis and aspects related to its prevention.: Methods: integrative review after a search in the databases LILACS and MEDLINE, carried ...

Abstract	Objectives: to identify the scientific evidence about the clinical complications and manifestations of congenital syphilis and aspects related to its prevention. Methods: integrative review after a search in the databases LILACS and MEDLINE, carried out in March 2018, using the descriptors "syphilis, congenital", "complications", and "signs and symptoms", leading to the selection of 27 researches. Results: the publications found were published from 1966 to 2017, and most of them were from Latin America and Africa. Negative outcomes, laboratory changes, and the clinical manifestations in congenital syphilis, whether early or delayed, were, respectively: low weight at birth, anemia, hepatosplenomegaly, and dental alterations. The lack of treatment of the pregnant women in the prenatal was the most common occasion in which the opportunity to prevent the complications of congenital syphilis was lost. Conclusions: the scientific evidences analyzed showed serious complications of congenital syphilis that could be avoided if early opportunities of diagnosing and treating the pregnant women are not lost during the prenatal.
MeSH term(s)	Female ; Humans ; Infant, Newborn ; Parturition ; Pregnancy ; Pregnancy Complications, Infectious/prevention & control ; Syphilis/complications ; Syphilis/diagnosis ; Syphilis/prevention & control ; Syphilis, Congenital/complications ; Syphilis, Congenital/prevention & control
Language	Portuguese
Publishing date	2021-07-14
Publishing country	Brazil
Document type	Journal Article ; Review
ZDB-ID	731983-6
ISSN	1984-0446 ; 0034-7167
ISSN (online)	1984-0446
ISSN	0034-7167
DOI	10.1590/0034-7167-2019-0318
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Article ; Online: Factors associated with prematurity in reported cases of congenital syphilis.

Araújo, Maria Alix Leite / Esteves, Ana Beatriz Barbosa / Rocha, Ana Fátima Braga / Silva Junior, Geraldo Bezerra da / Miranda, Angelica Espinosa

Revista de saude publica

2021 Volume 55, Page(s) 28

Abstract: Objective: To analyze the factors associated with prematurity in reported cases of congenital syphilis in the city of Fortaleza, Ceará, Brazil.: Methods: Cross-sectional study conducted in ten public maternity hospitals in Fortaleza, Ceará, Brazil. A ...

Abstract	Objective: To analyze the factors associated with prematurity in reported cases of congenital syphilis in the city of Fortaleza, Ceará, Brazil. Methods: Cross-sectional study conducted in ten public maternity hospitals in Fortaleza, Ceará, Brazil. A total of 478 reported cases of congenital syphilis were included in 2015, and data were collected from notification forms, from mothers' and babies' medical records and from prenatal cards. For the bivariate analysis, Pearson's chi-squared and Fisher's exact tests were used, considering p < 0.05. Multiple logistic regression was conducted, presenting odds ratio (OR) with a 95% confidence interval. Results: We found 15.3% prematurity in pregnant women with syphilis. The titration of the VDRL test > 1:8 at delivery (OR 2.46; 95%CI: 1.33-4.53; p = 0.004) and the non-treatment of the pregnant women or treatment with drugs other than penicillin during prenatal care (OR 3.52; 95%CI: 1.74-7.13; p< 0.001) were associated with higher chances of prematurity. Conclusion: The prematurity due to congenital syphilis is a preventable condition, provided that pregnant women with syphilis are treated appropriately. Weaknesses in prenatal care are associated with this outcome, which highlights the importance of public policies oriented to improve the quality of prenatal care.
MeSH term(s)	Brazil/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Pregnancy ; Pregnancy Complications, Infectious/epidemiology ; Prenatal Care ; Syphilis/complications ; Syphilis/epidemiology ; Syphilis, Congenital/epidemiology
Language	Portuguese
Publishing date	2021-05-17
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	732179-x
ISSN	1518-8787 ; 0034-8910
ISSN (online)	1518-8787
ISSN	0034-8910
DOI	10.11606/s1518-8787.2021055002400
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Article ; Online: Estimated glomerular filtration rate in clinical practice: Consensus positioning of the Brazilian Society of Nephrology (SBN) and Brazilian Society of Clinical Pathology and Laboratory Medicine (SBPC/ML).

Kirsztajn, Gianna Mastroianni / Silva Junior, Geraldo Bezerra da / Silva, Artur Quintiliano Bezerra da / Abensur, Hugo / Romão Junior, João Egídio / Bastos, Marcus Gomes / Calice-Silva, Viviane / Carmo, Lilian Pires de Freitas do / Sandes-Freitas, Tainá Veras de / Abreu, Patrícia Ferreira / Andreguetto, Bruna Dolci / Cortes, Luiz Gustavo Ferreira / Oliveira, Maria Gabriela de Lucca / Vieira, Luisane Maria Falci / Moura-Neto, José A / Andriolo, Adagmar

Jornal brasileiro de nefrologia

2024 Volume 46, Issue 3, Page(s) e20230193

Abstract: Chronic kidney disease (CKD) represents one of today's main public health problems. Serum creatinine measurement and estimation of the glomerular filtration rate (GFR) are the main tools for evaluating renal function. There are several equations to ... ...

Abstract	Chronic kidney disease (CKD) represents one of today's main public health problems. Serum creatinine measurement and estimation of the glomerular filtration rate (GFR) are the main tools for evaluating renal function. There are several equations to estimate GFR, and CKD-EPI equation (Chronic Kidney Disease - Epidemiology) is the most recommended one. There are still some controversies regarding serum creatinine measurement and GFR estimation, since several factors can interfere in this process. An important recent change was the removal of the correction for race from the equations for estimating GFR, which overestimated kidney function, and consequently delayed the implementation of treatments such as dialysis and kidney transplantation. In this consensus document from the Brazilian Societies of Nephrology and Clinical Pathology and Laboratory Medicine, the main concepts related to the assessment of renal function are reviewed, as well as possible existing controversies and recommendations for estimating GFR in clinical practice.
MeSH term(s)	Humans ; Glomerular Filtration Rate ; Nephrology ; Creatinine ; Brazil ; Consensus ; Renal Dialysis ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/therapy ; Pathology, Clinical
Chemical Substances	Creatinine (AYI8EX34EU)
Language	Portuguese
Publishing date	2024-04-05
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2057873-8
ISSN	2175-8239 ; 2175-8239
ISSN (online)	2175-8239
ISSN	2175-8239
DOI	10.1590/2175-8239-JBN-2023-0193en
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