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  1. Article ; Online: ORAL CARCINOMA ARISING UNDER IMPLANT-SUPPORTED PROSTHESIS: PROGRESSION OF PROLIFERATIVE VERRUCOUS LEUKOPLAKIA INITIALLY MIMICKING LICHEN PLANUS.

    Silva, Paula Verona Ragusa / Palaçon, Mariana Paravani / Silveira, Heitor Albergoni / Martins, Karina Helen / Bufalino, Andreia / León, Jorge Esquiche

    The Journal of oral implantology

    2024  

    Language English
    Publishing date 2024-05-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 448462-9
    ISSN 1548-1336 ; 0160-6972
    ISSN (online) 1548-1336
    ISSN 0160-6972
    DOI 10.1563/aaid-joi-D-24-00056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Dual-Task Performance, Balance and Aerobic Capacity as Predictors of Falls in Older Adults with Cardiovascular Disease: A Comparative Study.

    Silveira, Heitor / Lima, Juliana / Plácido, Jessica / Ferreira, José Vinícius / Ferreira, Renan / Laks, Jerson / Deslandes, Andrea

    Behavioral sciences (Basel, Switzerland)

    2023  Volume 13, Issue 6

    Abstract: Cardiovascular diseases (CVD) are highly prevalent and strongly associated with the risk of falls in the elderly. Falls are associated with impairments in cognition and functional or gait performance; however, little is known about these associations in ... ...

    Abstract Cardiovascular diseases (CVD) are highly prevalent and strongly associated with the risk of falls in the elderly. Falls are associated with impairments in cognition and functional or gait performance; however, little is known about these associations in the elderly population with CVD. In this study, we aimed to clarify the possible associations of physical capacity and functional and cognitive outcomes with the incidence of falls in older adults with CVD. In this comparative study, 72 elderly patients were divided into fallers (
    Language English
    Publishing date 2023-06-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651997-5
    ISSN 2076-328X
    ISSN 2076-328X
    DOI 10.3390/bs13060488
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Lymphomatoid Papulosis "Type E" Affecting the Palate: A Detailed Case Report and Review of Literature.

    Silveira, Heitor Albergoni / Ragusa Silva, Paula Verona / Pimentel, Bruna Gonçalves / Nogueira, Gustavo Milhomens / Chahud, Fernando / Brunaldi, Mariângela Ottoboni / León, Jorge Esquiche

    The American Journal of dermatopathology

    2023  Volume 45, Issue 5, Page(s) 326–329

    Abstract: Abstract: Lymphomatoid papulosis (LyP) belongs to the spectrum of primary cutaneous CD30 + lymphoproliferative disorders, characterized by chronic, recurrent, self-healing papules, small nodules, or ulcers. The clinicopathological features of LyP can ... ...

    Abstract Abstract: Lymphomatoid papulosis (LyP) belongs to the spectrum of primary cutaneous CD30 + lymphoproliferative disorders, characterized by chronic, recurrent, self-healing papules, small nodules, or ulcers. The clinicopathological features of LyP can mimic overt lymphomas. To date, about 27 intraoral LyP cases have been reported. Of them, only 2 cases were diagnosed as angioinvasive LyP (type E). Herein, we report a 24-year-old Brazilian man who presented a large ulcerated lesion on the hard palate with rapid evolution. Remarkably, there was no involvement of the skin or other mucous membranes. Microscopy revealed a lymphoid infiltrate constituted by medium-sized to large atypical cells, with angiocentric and angiodestructive features. The atypical cells showed immunopositivity for CD3, CD8, CD30, CD56, granzyme B, perforin, and focally for MUM1/IRF4. Ki-67 highlighted almost all atypical lymphoid cells, whereas EBER1/2 was negative. After 2 months of follow-up, the lesion healed completely. Although rare, LyP type E should be included in the differential diagnosis of oral ulcers.
    MeSH term(s) Male ; Humans ; Young Adult ; Adult ; Lymphomatoid Papulosis/pathology ; Skin Neoplasms/pathology ; Skin/pathology ; Diagnosis, Differential ; Palate/pathology
    Language English
    Publishing date 2023-03-20
    Publishing country United States
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 448469-1
    ISSN 1533-0311 ; 0193-1091
    ISSN (online) 1533-0311
    ISSN 0193-1091
    DOI 10.1097/DAD.0000000000002405
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Lingual Actinomycosis Clinically Simulating Nodular Median Rhomboid Glossitis: Literature Review and Report of Additional Case.

    Reyes, Magdalena Raquel Torres / Dominguete, Matheus Henrique Lopes / Javaroni, Julia Biliato / da Silveira, Heitor Albergoni / Silva, Evânio Vilela / León, Jorge Esquiche

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2023  Volume 75, Issue 4, Page(s) 3984–3987

    Abstract: Actinomycosis is an uncommon, subacute to chronic, suppurative bacterial infection caused by Actinomyces Israelii. About 3% of all actinomycosis cases occur in the tongue, often affecting adult patients (mean age, 50 years). The clinical characteristics ... ...

    Abstract Actinomycosis is an uncommon, subacute to chronic, suppurative bacterial infection caused by Actinomyces Israelii. About 3% of all actinomycosis cases occur in the tongue, often affecting adult patients (mean age, 50 years). The clinical characteristics of actinomycosis can resemble malignant or benign tumors, and other infectious diseases. A 56-year-old woman was referred presenting an ulcerated lesion on the tongue 1 year ago. Intraoral examination revealed an edematous nodular lesion with an ulcerated surface, slightly symptomatic, on the midline dorsum of posterior tongue, suggesting nodular median rhomboid glossitis. Cytology smear was negative for fungus. After excisional biopsy, histopathological examination showed a chronic inflammatory infiltrate supported by a fibrovascular connective tissue stroma, and at the deepest part, broad basophilic areas surrounded by neutrophils, containing numerous filamentous bacilli, which were highlighted by Gram and Groccott-Gomori staining. The final diagnosis was lingual actinomycosis. Oral amoxicillin treatment (8/8 h for 2 weeks) was started, and after 1-month complete resolution was observed. Lingual actinomycosis is a rare lesion that must be recognized by dentists, because its early diagnosis and correct treatment reduce the possibility of a clinical complication that compromises the patient's quality of life. Noteworthy, when located on the midline dorsum of posterior tongue, actinomycosis can simulate nodular median rhomboid glossitis, expanding its spectrum of clinical differential diagnosis.
    Language English
    Publishing date 2023-06-30
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-023-04045-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Lip Granular Cell Tumor (GCT) in a Pediatric Patient: Critical Literature Review on Pediatric Intraoral GCT and Acquired and Congenital Intraoral Non-Neural GCT.

    Javaroni, Julia Biliato / Silveira, Heitor Albergoni / Reyes, Magdalena Raquel Torres / Mesquita, Ana Terezinha Marques / Rocha, Gabriela Fonseca / León, Jorge Esquiche

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2023  Volume 75, Issue 4, Page(s) 3920–3924

    Abstract: Granular cell tumor (GCT) is an uncommon benign neoplasm derived from Schwann cells, frequently affecting the oral cavity, skin, and gastrointestinal tract. On microscopy, pseudocarcinomatous squamous hyperplasia (PSH) and perineural involvement are ... ...

    Abstract Granular cell tumor (GCT) is an uncommon benign neoplasm derived from Schwann cells, frequently affecting the oral cavity, skin, and gastrointestinal tract. On microscopy, pseudocarcinomatous squamous hyperplasia (PSH) and perineural involvement are potential diagnostic pitfalls. GCT should be differentiated from non-neural GCT (NN-GCT). A 13-year-old male patient was referred presenting a nodular lesion on the upper lip several months ago. After excisional biopsy, microscopy revealed GCT without PSH but presenting multifocal perineural involvement. By immunohistochemistry, ALK was negative, whereas Rb and INI1 expression was intact. Moreover, with few intraoral NN-GCTs being assessed, recent studies suggest that acquired dermal NN-GCT subgroup seems to correspond to ALK-rearranged variants of epithelioid fibrous histiocytoma. Accordingly, further research on this topic is strongly encouraged.
    Language English
    Publishing date 2023-06-17
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-023-03957-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Non-Ulcerated and Ulcerated Necrotizing Sialometaplasia: Report of an Additional Case and Literature Review.

    Silva, Evânio Vilela / Silveira, Heitor Albergoni / Moreira, Thales Peres Candido / Augusto, Jefferson / Silva, Paula Verona Ragusa / Bufalino, Andreia / León, Jorge Esquiche

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2023  Volume 75, Issue 3, Page(s) 2302–2305

    Abstract: Necrotizing sialometaplasia (NS) is a rare, self-limiting, necrotizing inflammatory lesion, often involving the minor salivary glands of the palate. NS occurs often in men (60%) older than 45 years. Commonly, it presents as an ulcerative lesion, ... ...

    Abstract Necrotizing sialometaplasia (NS) is a rare, self-limiting, necrotizing inflammatory lesion, often involving the minor salivary glands of the palate. NS occurs often in men (60%) older than 45 years. Commonly, it presents as an ulcerative lesion, measuring 1 to 3 cm in diameter, with an evolution time of a few weeks or days, simulating malignancy. However, in some instances, the mucosal surface is intact, thus emphasizing the importance of considering NS in the differential diagnosis of oral ulcerative and non-ulcerative lesions. To date, 12 cases of non-ulcerated NS in the palate have been reported. Here, we report a 50-year-old male patient who presented a non-ulcerated, asymptomatic, nodular swelling 3 months ago, located on the hard palate, clinically suggesting salivary gland tumor or lymphoproliferative disorder. After biopsy, a diagnosis of non-ulcerated NS was established. After 4 weeks, the lesion evolved with complete resolution. After literature review, notably, unlike ulcerated NS, the non-ulcerated NS affected patients a decade younger (33 years vs. 45 years), with marked female predilection (83% vs. 40%) and not uncommon bilateral presentation (33% vs. 10%). NS should be considered in the differential diagnosis of ulcerative and non-ulcerative lesions affecting the palate.
    Language English
    Publishing date 2023-02-27
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-023-03609-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Intraoral epithelioid and spindle cell hemangioma associated with pseudoepitheliomatous hyperplasia: An immunohistochemical study.

    Silva, Evânio Vilela / Dominguete, Matheus Henrique Lopes / Martins, Karina Helen / Reyes, Magdalena Raquel Torres / Silveira, Heitor Albergoni / da Silva, Anderson Tangerino Ferreira / León, Jorge Esquiche

    Journal of cutaneous pathology

    2023  Volume 51, Issue 2, Page(s) 83–87

    MeSH term(s) Humans ; Hyperplasia ; Hemangioma ; Skin Neoplasms ; Skin Diseases ; Precancerous Conditions
    Language English
    Publishing date 2023-11-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 187078-6
    ISSN 1600-0560 ; 0303-6987
    ISSN (online) 1600-0560
    ISSN 0303-6987
    DOI 10.1111/cup.14555
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Intraoral primary syphilis mimicking lymphoproliferative disorder.

    E Silva, Larissa Doalla de Almeida / Silva, Evânio Vilela / Silveira, Heitor Albergoni / Silva, Herberth Campos / Chahud, Fernando / León, Jorge Esquiche / Mesquita, Ana Terezinha Marques

    Journal of cutaneous pathology

    2023  Volume 51, Issue 3, Page(s) 209–213

    Abstract: Syphilis can mimic, clinically and microscopically, many other diseases. By microscopy, typically syphilis presents with plasma cell infiltration, admixed with lymphocytes and macrophages, in lichenoid and/or perivascular/perineural distribution pattern. ...

    Abstract Syphilis can mimic, clinically and microscopically, many other diseases. By microscopy, typically syphilis presents with plasma cell infiltration, admixed with lymphocytes and macrophages, in lichenoid and/or perivascular/perineural distribution pattern. When exuberant, this inflammatory infiltrate can mimic a lymphoproliferative disorder (LPD), notably plasma cell neoplasia or lymphoma. To date, about 12 cases of secondary syphilis, all but one in extraoral location, suggesting initially a LPD, have been published. Here, to our knowledge, we report an unusual case of intraoral primary syphilis initially suggesting LPD, notably lymphoid hyperplasia (pseudolymphoma); however, mucosa-associated lymphoid tissue (MALT) lymphoma and follicular lymphoma could not be disregarded. Polyclonality of plasma cells on immunohistochemistry, in strict clinical correlation, was essential to arrive at the correct diagnosis.
    MeSH term(s) Humans ; Syphilis/diagnosis ; Syphilis/pathology ; Lymphoproliferative Disorders/diagnosis ; Lymphoproliferative Disorders/pathology ; Lymphoma, B-Cell, Marginal Zone/pathology ; Lymphocytes/pathology ; Diagnosis, Differential
    Language English
    Publishing date 2023-12-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 187078-6
    ISSN 1600-0560 ; 0303-6987
    ISSN (online) 1600-0560
    ISSN 0303-6987
    DOI 10.1111/cup.14567
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Pseudocarcinomatous Squamous Hyperplasia After Surgical Management Of Pediatric Ameloblastoma: An Immunohistochemical Study.

    Amaral, Eloísa Costa / Javaroni, Julia Biliato / Silveira, Heitor Albergoni / Trivellato, Alexandre Elias / Sverzut, Cássio Edvard / León, Jorge Esquiche

    Journal of maxillofacial and oral surgery

    2023  Volume 22, Issue 3, Page(s) 741–745

    Abstract: Pseudocarcinomatous squamous hyperplasia (PSH) affecting the jaws is uncommon. The mandible is the most common location, usually as a complication associated with osteomyelitis, medication-related osteonecrosis or osteoradionecrosis. Herein, we report an ...

    Abstract Pseudocarcinomatous squamous hyperplasia (PSH) affecting the jaws is uncommon. The mandible is the most common location, usually as a complication associated with osteomyelitis, medication-related osteonecrosis or osteoradionecrosis. Herein, we report an 8-year-old male patient presenting a solid ameloblastoma, plexiform type, who was treated by segmental mandibulectomy with bone grafting. Three months later, on the underlying graft, a sinus tract was observed, and a small bone fragment was resected which was diagnosed as bone sequestration associated with PSH. After 7-year follow-up, the patient is well, without alterations. To our knowledge, for the first time, we report in detail the immunohistochemical features of PSH which, in addition to epithelial component profile and chronic inflammatory cells, revealed a diffuse infiltration by dendritic cells, suggesting that epithelial cell-immune cell interactions in PSH pathogenesis should also be considered.
    Language English
    Publishing date 2023-04-08
    Publishing country India
    Document type Case Reports
    ZDB-ID 2502352-4
    ISSN 0974-942X ; 0972-8279
    ISSN (online) 0974-942X
    ISSN 0972-8279
    DOI 10.1007/s12663-023-01912-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Microscopical Diagnosis of Oral Leishmaniasis: Kinetoplast.

    Silveira, Heitor Albergoni / Panucci, Beatriz Zamboni Martins / Silva, Evanio Vilela / Mesquita, Ana Terezinha Marques / León, Jorge Esquiche

    Head and neck pathology

    2021  Volume 15, Issue 3, Page(s) 1085–1086

    MeSH term(s) Aged ; Humans ; Inclusion Bodies/pathology ; Leishmaniasis, Cutaneous/pathology ; Male ; Mouth Diseases/pathology
    Language English
    Publishing date 2021-02-18
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 2407834-7
    ISSN 1936-0568 ; 1936-055X
    ISSN (online) 1936-0568
    ISSN 1936-055X
    DOI 10.1007/s12105-021-01304-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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