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  1. Article ; Online: Instrumented L5-S1 interbody graft with IFUSE implant using the reverse Bohlman technique.

    Chevillotte, Thomas / Darnis, Alice / Grobost, Pierre / Palmano, Marine / Guedj, Jérémie / Silvestre, Clément

    Neuro-Chirurgie

    2024  , Page(s) 101560

    Abstract: Background: In case of high sacral slope, anterior lumbosacral fusions can be performed by retroperitoneal or transperitoneal approach using a reversed Bohlman technique with an autologous corticocancellous fibular graft. The use of a trans-lumbosacral ... ...

    Abstract Background: In case of high sacral slope, anterior lumbosacral fusions can be performed by retroperitoneal or transperitoneal approach using a reversed Bohlman technique with an autologous corticocancellous fibular graft. The use of a trans-lumbosacral implant can avoid the iatrogenic effects but currently, there is no implant specifically designed for this fusion technique. Could the IFUSE implant from SI BONE replace a fibular graft to avoiding the iatrogenic effect induced by sampling during a Reverse Bohlman technique?
    Patients and methods: We present the case of a 38-year-old woman with L5S1 interbody pseudarthrosis after posterior fixation for grade 2 L5-S1 spondylolisthesis with isthmic lysis of L5, and that of a 69-year-old woman who underwent a posterior T4 fusion to the pelvis for degenerative scoliosis. Both required a trans-lumbosacral instrumented fusion via an anterior approach using the reverse Bohlman technique. Surgical technique was described.
    Results: There were no perioperative or postoperative complications. At 6 months, the patients reported a decrease in lumbar and radicular symptomatology. There were no infectious, neurological or vascular complications. CT-scans confirmed the good position and stability of the IFUSE implant.
    Discussion: We present an innovative interbody grafting technique adapted to spines with high pelvic incidence. The surgical technique is safe, minimally invasive, and reduces surgical iatrogeny. The short and medium-term results are positive but require longer-term follow-up and a larger cohort.
    Language English
    Publishing date 2024-04-13
    Publishing country France
    Document type Journal Article
    ZDB-ID 207146-0
    ISSN 1773-0619 ; 0028-3770 ; 0150-9586
    ISSN (online) 1773-0619
    ISSN 0028-3770 ; 0150-9586
    DOI 10.1016/j.neuchi.2024.101560
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    Uk I Zs.196: Show issues Location:
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  2. Article: Early Revision Surgery for Distal Adding-On Correction in Lenke 1 and 2 Adolescent Idiopathic Scoliosis.

    El Rachkidi, Rami / Silvestre, Clément / Roussouly, Pierre

    Cureus

    2022  Volume 14, Issue 11, Page(s) e30960

    Abstract: Objective To evaluate the outcome of an early revision strategy for postoperative distal adding-on (DAO) after Lenke 1 and 2 adolescent idiopathic scoliosis (AIS) surgery. Summary of background data Improper choice of the lowest instrumented vertebra ( ... ...

    Abstract Objective To evaluate the outcome of an early revision strategy for postoperative distal adding-on (DAO) after Lenke 1 and 2 adolescent idiopathic scoliosis (AIS) surgery. Summary of background data Improper choice of the lowest instrumented vertebra (LIV) is a major cause of postoperative imbalance and unsatisfactory results in AIS surgery. The long-term consequences of such imbalance remain unclear. Early corrective surgery has not been described. Methods We retrieved the records of operated AIS patients at the former institution of the senior author. There were 18 cases of early revision by one-level distal extension of instrumentation and fusion. Patients were reoperated based on progressive distal local imbalance and clinical lumbar asymmetry. Several local and global balance parameters were compared on serial long-standing radiographs before and after the index surgery, before and after the revision surgery, and at the last follow-up. The Kruskal-Wallis test was used for the comparison of the results. A value of p<0.05 was considered significant. Results All patients were female with a mean age of 13.9 years. The mean delay between the two surgeries was 8.4 months and the last follow-up was at 32.5 months after the revision surgery. Unsatisfactory results after the index surgery were reflected by a progressive increase in disc angulation below the lowest instrumented vertebra (LIV) and an increased tilt and rotation of the LIV+1. The clinical lumbar shift was also accentuated from 19 mm to 25 mm. Revision surgery significantly reduced local and global balance parameters. There was a decrease in the LIV translation (from 26 mm to 19 mm) and of the wedging below it (from 7.9° to 1.3°) and a better positioning of the LIV+1 with less tilt (from 14.6° to 3.6°), translation (from 22.2 mm to 13.8 mm) and rotation (from 20° to 15°). The clinical lumbar shift was reduced from 25 mm to 3.6 mm. Global coronal and sagittal balance were also ameliorated. All results were maintained at a mean follow-up of 32.5 months from the revision surgery. No complications were noted and there was no need for a blood transfusion. Conclusion The revision surgery proposed in this paper is simple with low morbidity and may be considered as a fine-tuning of the failed index surgery. Further studies are needed to evaluate the long-term consequences of treated and untreated postoperative distal adding-on in AIS surgery.
    Language English
    Publishing date 2022-11-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.30960
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  3. Article ; Online: Electrical impedance tomography in clinical use: Unnecessary technology or a unique angle in respiratory monitoring?

    Davies, Patrick / Silvestre, Catarina

    Pediatric pulmonology

    2020  Volume 55, Issue 4, Page(s) 845–846

    MeSH term(s) Electric Impedance ; Hamartoma ; Humans ; Infant ; Positive-Pressure Respiration ; Thoracic Wall ; Tomography
    Language English
    Publishing date 2020-01-29
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 632784-9
    ISSN 1099-0496 ; 8755-6863
    ISSN (online) 1099-0496
    ISSN 8755-6863
    DOI 10.1002/ppul.24668
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    Zs.A 2143: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article ; Online: Long-term clinical sequelae and socio-professional performance in craniopharyngioma patients.

    Cosme, Inês / Gomes, Ana R / Reis, Dinis / Nobre, Ema L / Alexandre, Maria I / Gomes, Vânia / Marques, Pedro / Silvestre, Catarina

    Minerva endocrinology

    2024  

    Abstract: Background: Craniopharyngioma (CP) is a rare tumor, leading to several post-treatment sequelae which may have significant clinical and social implications, including impaired academic performance or employability.: Methods: We conducted a ... ...

    Abstract Background: Craniopharyngioma (CP) is a rare tumor, leading to several post-treatment sequelae which may have significant clinical and social implications, including impaired academic performance or employability.
    Methods: We conducted a retrospective study involving CP patients followed at our center between 1986 and 2020. Data on demographics, clinical, imaging, and treatment characteristics were collected from the clinical records.
    Results: There were 33 patients (current mean age of 49.8±18.7 years), being 22 diagnosed in adulthood. The average follow-up duration was 16.03±9.3 years. Twelve patients were treated with surgery alone, while 21 underwent surgery and radiotherapy. Pituitary and hypothalamic deficits were more frequent in treated with surgery, whereas visual defects and metabolic diseases were more frequent in treated with surgery and radiotherapy. There were no differences between age of onset groups and type of sequelae. After diagnosis, nine patients concluded their academic training. In childhood-onset group, after diagnosis, one patient was retired, three continue studying and the others concluded schooling. In the other group, six patients were retired and two concluded schooling. There was no association between academic performance or employability and the type of treatment. CP patients academic performance was not worse comparing with general Portuguese population.
    Conclusions: Long-term sequelae may not be related with the age of CP onset, but may vary according to the type of treatment. There was a wide variety of clinical sequelae with extended follow-up, however academic performance and employability seemed not affected. CP diagnosis in an early period of life may not compromise the academic success of patients.
    Language English
    Publishing date 2024-02-15
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062786-2
    ISSN 2724-6116
    ISSN (online) 2724-6116
    DOI 10.23736/S2724-6507.22.03719-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2105: Show issues Location:
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  5. Article: The Ultrasound Renal Stress Test for the Assessment of Functional Renal Reserve in Kidney Transplantation: A Pilot Study in Living Donors.

    Nalesso, Federico / Martino, Francesca K / Bogo, Marco / Bettin, Elisabetta / Alessi, Marianna / Stefanelli, Lucia F / Silvestre, Cristina / Furian, Lucrezia / Calò, Lorenzo A

    Journal of clinical medicine

    2024  Volume 13, Issue 2

    Abstract: In the evolving landscape of nephrology and kidney transplants, assessing renal functional reserve (RFR) in living kidney donors is essential for ensuring donor safety and successful transplantation. This study explores the use of the Intra-Parenchymal ... ...

    Abstract In the evolving landscape of nephrology and kidney transplants, assessing renal functional reserve (RFR) in living kidney donors is essential for ensuring donor safety and successful transplantation. This study explores the use of the Intra-Parenchymal Renal Resistive Index Variation (IRRIV) test, a novel non-invasive method, to measure RFR in living donors. Our observational study included 11 participants undergoing living kidney donations, evaluated using the IRRIV-based Renal Stress Test (RST) before and 12 months post-nephrectomy. The study demonstrated significant changes in creatinine and eGFR CKD-EPI levels post-donation, with an average creatinine rise from 69 to 97 µmol/L and a reduction in eGFR from 104 to 66 mL/min/1.73 m
    Language English
    Publishing date 2024-01-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13020525
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  6. Article ; Online: Adaptive control with unknown mass estimation for a quadrotor-slung-load system.

    Yu, Gan / Xie, Wei / Cabecinhas, David / Cunha, Rita / Silvestre, Carlos

    ISA transactions

    2022  Volume 133, Page(s) 412–423

    Abstract: In aerial load transportation applications, knowing the mass of the load in advance is not always possible. The load dynamics depend on its mass and using a high-performance model-based controller with an inaccurate mass will introduce unmodeled ... ...

    Abstract In aerial load transportation applications, knowing the mass of the load in advance is not always possible. The load dynamics depend on its mass and using a high-performance model-based controller with an inaccurate mass will introduce unmodeled disturbances to the system that will negatively affect the closed-loop performance. This paper addresses the design of a trajectory tracking controller for a quadrotor with a slung-load that has an unknown mass. The proposed solution is an adaptive controller with online estimation designed using the backstepping technique. Nonlinear control laws for thrust and angular velocity, and an adaption law for mass estimation are proposed, which guarantee the convergence of the trajectory tracking and the estimation errors to zero, and are robust to variations in load mass. Simulation and experimental results are presented to assess the validity and performance of the proposed controller.
    Language English
    Publishing date 2022-06-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012746-7
    ISSN 1879-2022 ; 0019-0578
    ISSN (online) 1879-2022
    ISSN 0019-0578
    DOI 10.1016/j.isatra.2022.06.036
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  7. Article ; Online: Interstitial lung abnormalities: Real-world evidence.

    Rôlo Silvestre, Carina / Custódio, Catarina / Clemente, Susana / Rodrigues, Silvia / Furtado, Sofia Tello / Maio, Rui

    Health science reports

    2023  Volume 6, Issue 4, Page(s) e1216

    Language English
    Publishing date 2023-04-21
    Publishing country United States
    Document type Journal Article
    ISSN 2398-8835
    ISSN (online) 2398-8835
    DOI 10.1002/hsr2.1216
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  8. Book ; Online: robust synergistic hybrid feedback

    Casau, Pedro / Sanfelice, Ricardo G. / Silvestre, Carlos

    2022  

    Abstract: Synergistic hybrid feedback refers to a collection of feedback laws that allow for global asymptotic stabilization of a compact set through the following switching logic: given a collection of Lyapunov functions that are indexed by a logic variable, ... ...

    Abstract Synergistic hybrid feedback refers to a collection of feedback laws that allow for global asymptotic stabilization of a compact set through the following switching logic: given a collection of Lyapunov functions that are indexed by a logic variable, whenever the currently selected Lyapunov function exceeds the value of another function in the collection by a given margin, then a switch to the corresponding feedback law is triggered. This kind of feedback has been under development over the past decade and it has led to multiple solutions for global asymptotic stabilization on compact manifolds. The contributions of this paper include a synergistic controller design in which the logic variable is not necessarily constant between jumps, a synergistic hybrid feedback that is able to tackle the presence of parametric uncertainty, backstepping of adaptive synergistic hybrid feedbacks, and a demonstration of the proposed solutions to the problem of global obstacle avoidance.

    Comment: 17 pages, 2 figures, submitted for publication
    Keywords Electrical Engineering and Systems Science - Systems and Control
    Subject code 515
    Publishing date 2022-12-31
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Comment and questions on "Technical approach, outcomes, and exposure-related complications in patients undergoing anterior lumbar interbody fusion".

    Chevillotte, Thomas / Bordet, Marine / Millon, Antoine / Silvestre, Clément / Tresson, Philippe

    Journal of vascular surgery

    2021  Volume 74, Issue 1, Page(s) 349

    MeSH term(s) Humans ; Lumbosacral Region ; Spinal Fusion/adverse effects
    Language English
    Publishing date 2021-06-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 605700-7
    ISSN 1097-6809 ; 0741-5214
    ISSN (online) 1097-6809
    ISSN 0741-5214
    DOI 10.1016/j.jvs.2021.01.072
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    Zs.A 1933: Show issues Location:
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  10. Article: Characterization of

    Bernat-Silvestre, Cesar / Ma, Yingxuan / Johnson, Kim / Ferrando, Alejandro / Aniento, Fernando / Marcote, María Jesús

    Frontiers in plant science

    2022  Volume 13, Page(s) 817915

    Abstract: Lipid remodeling of Glycosylphosphatidylinositol (GPI) anchors is required for their maturation and may influence the localization and function of GPI-anchored proteins (GPI-APs). Maturation of GPI-anchors is well characterized in animals and fungi but ... ...

    Abstract Lipid remodeling of Glycosylphosphatidylinositol (GPI) anchors is required for their maturation and may influence the localization and function of GPI-anchored proteins (GPI-APs). Maturation of GPI-anchors is well characterized in animals and fungi but very little is known about this process in plants. In yeast, the GPI-lipid remodeling occurs entirely at the ER and is initiated by the remodeling enzyme Bst1p (Post-Glycosylphosphatidylinositol Attachment to Proteins inositol deacylase 1 -PGAP1- in mammals and
    Language English
    Publishing date 2022-02-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2022.817915
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