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  1. Article ; Online: Evaluation of process indicators of a medication review service between pharmacists and physicians.

    Marques, Tatiane C / Silva, Rafaella de Oliveira Santos / Dos Santos Júnior, Genival A / de Jesus Júnior, Francisco C / Silvestre, Carina C / Rocha, Kérilin S S / da Rocha, Chiara E / Brito, Giselle de Carvalho / de Lyra-Jr, Divaldo P

    Journal of evaluation in clinical practice

    2019  Volume 26, Issue 5, Page(s) 1448–1456

    Abstract: Rationale, aims and objectives: Literature have showed inconclusive or contradictory results regarding medication review services effectiveness in optimizing process indicators. Thus, this study aimed to evaluate the process indicators of a medication ... ...

    Abstract Rationale, aims and objectives: Literature have showed inconclusive or contradictory results regarding medication review services effectiveness in optimizing process indicators. Thus, this study aimed to evaluate the process indicators of a medication review service between pharmacists and physicians.
    Method: This quasi-experimental study was conducted between March 2013 and February 2014 with patients who were receiving care in a medication review service in a teaching hospital in northeastern Brazil. The main process indicators were number of pharmaceutical consultations; identification and resolution of drug-related problems (DRP) and pharmaceutical interventions that were classified according to type and degree of acceptance. Descriptive statistics were used to report data. The statistical significance of the association between variables was evaluated using the Mantel-Haenszel chi-square test. The 95% confidence interval was considered, and differences were deemed statistically significant if P ≤ .05.
    Results: A total of 146 patients attended the medication review service. The number of consultations per patient ranged from one to five (2.1 ± 1.1). The service identified 366 DRP, most of which were indication (67.5%). Patients who had four to five pharmaceutical consultations were 1.14 times more likely to have their DRP identified (χ
    Conclusion: The collaborative medication review service optimized the process indicators. Drug-related problems identification and resolution required more than three pharmaceutical consultations. Most of the pharmaceutical interventions were accepted by prescribers. Thus, collaborative medication review services may be fundamental to the construction of more effective and safe health systems.
    MeSH term(s) Brazil ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Pharmacists ; Pharmacy Service, Hospital ; Physicians ; Referral and Consultation
    Language English
    Publishing date 2019-12-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1327355-3
    ISSN 1365-2753 ; 1356-1294
    ISSN (online) 1365-2753
    ISSN 1356-1294
    DOI 10.1111/jep.13332
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Development and content validation of an instrument to document the dispensing of prescribed medicines.

    Cerqueira-Santos, Sabrina / Rocha, Kérilin S S / Boaventura, Thays C / Jesus, Elisdete M S / Silvestre, Carina C / Alves, Bárbara M C Sodré- / de Lyra, Divaldo P

    Journal of clinical pharmacy and therapeutics

    2019  Volume 44, Issue 3, Page(s) 430–439

    Abstract: What is known and objective: Qualified dispensing is fundamental for the promotion of the rational use of medicines. Documentation is an indicator of quality and one of the essential steps in the care process. However, in Brazil, there are no models of ... ...

    Abstract What is known and objective: Qualified dispensing is fundamental for the promotion of the rational use of medicines. Documentation is an indicator of quality and one of the essential steps in the care process. However, in Brazil, there are no models of clinical documentation applicable to dispensing practices. Thus, the objective of this study was to develop and validate an instrument to document the dispensing process of prescribed medicines.
    Methods: A methodological development study was carried out from February 2017 to October 2017 in two stages, which were (i) the development of the instrument and (ii) content validation of the proposed instrument. The development phase comprised three stages, which were (i) the elaboration of the prototype based on a previously performed systematic review, (ii) academic brainstorming and (iii) a pre-Delphi consensus. The content validation process was performed using the Delphi technique. The instrument was sent to 40 experts with experience in dispensing, and the consensus among them was calculated using the content validity index (CVI). The study was approved by the Ethics Committee, and all participants signed an informed consent document detailing the terms of the study.
    Results: In the development stage, three versions of the instrument were generated, which were the prototype, version 1 (changed after academic brainstorming) and version 2 (changed after the pre-Delphi). In the content validation process of version 2 of the instrument, 23 experts returned their evaluation in the first round of the Delphi process and 17 in the second. All the items obtained a CVI >0.83, which resulted in the validation of the instrument. The final instrument comprised the following sections: general information, the identification of technical and legal problems of prescriptions, the conduct for the resolution of the technical and legal problems of prescriptions, medication dispensed, suspected drug-related problems, verbal guidance, written guidance, referral and the referral result.
    What is new and conclusion: The developed and validated instrument presents the main variables that should be documented during the dispensing process.
    MeSH term(s) Adult ; Brazil ; Delphi Technique ; Documentation/standards ; Female ; Humans ; Prescription Drugs/standards
    Chemical Substances Prescription Drugs
    Language English
    Publishing date 2019-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 639006-7
    ISSN 1365-2710 ; 0269-4727
    ISSN (online) 1365-2710
    ISSN 0269-4727
    DOI 10.1111/jcpt.12803
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Perceptions of nurses, pharmacists and physicians about medication reconciliation: A multicenter study.

    Aires-Moreno, Giulyane T / Silvestre, Carina C / Araújo, Dyego C S A / Matos, Vanessa T G / Marcon de Oliveira, Vanessa / Ferreira, Cristiane M / Vasconcelos-Pereira, Erica F / Lira, Ana R P / Chemello, Clarice / Oliveira, Layse M S / Oliveira-Filho, Alfredo D / Lyra, Divaldo P

    Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

    2020  Volume 28, Issue 11, Page(s) 1435–1439

    Language English
    Publishing date 2020-09-21
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 1378024-4
    ISSN 1319-0164
    ISSN 1319-0164
    DOI 10.1016/j.jsps.2020.09.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Quality analysis of research on the use of benzodiazepines by elderly patients in the emergency room: a systematic review.

    Couto, Ana Teresa R / Silva, Daniel T / Silvestre, Carina C / Lyra, Divaldo P / Quintans, Lucindo J

    European journal of clinical pharmacology

    2013  Volume 69, Issue 7, Page(s) 1343–1350

    Abstract: Purpose: To analyze the quality of research on the use of benzodiazepines (BZDs) in the emergency room by the elderly population through the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) initiative.: Methods: A ... ...

    Abstract Purpose: To analyze the quality of research on the use of benzodiazepines (BZDs) in the emergency room by the elderly population through the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) initiative.
    Methods: A systematic review was carried out according to the following steps: (1) identification of studies, in which studies were selected from different combinations of the descriptors "elderly-aged," "benzodiazepines," and "emergency room" in the EMBASE-MEDLINE, SciELO, Scopus, and Web of Science databases; (2) evaluation of studies, in which the title, abstract, and full text of the studies were assessed; (3) evaluation of the methodological quality of the studies. The criteria used were those included in the STROBE recommendations.
    Results: At the end of the selection process, only six articles were identified which met the specific criteria. The sample sizes in these studies varied from 118 to 1,611 patients. More than half (4) of the studies did not describe the type of design used, whereas all collected demographic data and analyzed details on the use of BZDs, such as type administered and/or its relationship to the symptoms, were shown. No article fully complied with the STROBE criteria.
    Conclusions: This review shows a lack of methodological quality in the studies performed to date that have evaluated the use of BZDs in elderly patients in emergency rooms. These findings should guide future research in this subject area, providing a more complete approach on aspects related to the use of medications by this specific population.
    MeSH term(s) Aged, 80 and over ; Aging ; Benzodiazepines/therapeutic use ; Biomedical Research/methods ; Biomedical Research/standards ; Emergency Service, Hospital ; Humans ; Psychotropic Drugs/therapeutic use ; Quality Control ; Research Design/standards
    Chemical Substances Psychotropic Drugs ; Benzodiazepines (12794-10-4)
    Language English
    Publishing date 2013-02-13
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review ; Systematic Review
    ZDB-ID 121960-1
    ISSN 1432-1041 ; 0031-6970
    ISSN (online) 1432-1041
    ISSN 0031-6970
    DOI 10.1007/s00228-012-1439-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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