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Article ; Online: Comparison of Radial Versus Femoral Access for Neuroendovascular Procedures in Very High Body Mass Index Individuals.

Kolb, Bradley / Joshi, Krishna / Sim, Justin / Radaideh, Yazan / Chen, Michael / Crowley, R Webster / Munich, Stephan

2023 Volume 184, Page(s) e32–e38

Abstract: Background: Femoral access (TFA) for neuroendovascular procedures may present a challenge in very high body mass index (BMI) individuals. Whether radial access (TRA) confers a comparative benefit in this specific population has not been studied.: ... ...

Abstract	Background: Femoral access (TFA) for neuroendovascular procedures may present a challenge in very high body mass index (BMI) individuals. Whether radial access (TRA) confers a comparative benefit in this specific population has not been studied. Methods: We retrospectively identified all patients undergoing neuroendovascular procedures at our center between 2017 and 2021 with BMI ≥35 kg/m Results: The primary outcome of any bleeding complication occurred in 7% of the femoral group and 2% of the radial group (odds ratio 4.2, 95% confidence interval 1.0-18.6, P = 0.0421). Radial access was also associated with significantly shorter mean procedure times (median 43 minutes for radial, median 58 minutes for femoral, P = 0.0009) and mean fluoroscopy exposure times (median 15 minutes for radial, median 20 minutes for femoral, P = 0.0003). There were no significant differences in nonaccess site complications, procedural failure, length of stay, or deaths during hospitalization. Conclusions: When compared to TRA, TFA was associated with a significantly greater rate of bleeding complications in very high BMI patients undergoing neuroendovascular procedures. Procedure time and fluoroscopy time were both significantly longer when using TFA compared to TRA in this patient population.
MeSH term(s)	Humans ; Body Mass Index ; Retrospective Studies ; Treatment Outcome ; Angiography ; Time Factors ; Radial Artery/surgery ; Catheterization, Peripheral/methods
Language	English
Publishing date	2023-12-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2023.12.007
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1159: Show issues

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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article: Predicting Chronic Subdural Hematoma Resolution and Time to Resolution Following Surgical Evacuation.

Chang, Cory L / Sim, Justin L / Delgardo, Mychael W / Ruan, Diana T / Connolly, E Sander

Frontiers in neurology

2020 Volume 11, Page(s) 677

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2020-07-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564214-5
ISSN	1664-2295
ISSN	1664-2295
DOI	10.3389/fneur.2020.00677
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Therapeutic Modulation of the Complement Cascade in Stroke.

Clarke, Alison R / Christophe, Brandon R / Khahera, Anadjeet / Sim, Justin L / Connolly, E Sander

Frontiers in immunology

2019 Volume 10, Page(s) 1723

Abstract: Stroke is a leading cause of death and disability worldwide and an increasing number of ischemic stroke patients are undergoing pharmacological and mechanical reperfusion. Both human and experimental models of reperfused ischemic stroke have implicated ... ...

Abstract	Stroke is a leading cause of death and disability worldwide and an increasing number of ischemic stroke patients are undergoing pharmacological and mechanical reperfusion. Both human and experimental models of reperfused ischemic stroke have implicated the complement cascade in secondary tissue injury. Most data point to the lectin and alternative pathways as key to activation, and C3a and C5a binding of their receptors as critical effectors of injury. During periods of thrombolysis use to treat stroke, acute experimental complement cascade blockade has been found to rescue tissue and improves functional outcome. Blockade of the complement cascade during the period of tissue reorganization, repair, and recovery is by contrast not helpful and in fact is likely to be deleterious with emerging data suggesting downstream upregulation of the cascade might even facilitate recovery. Successful clinical translation will require the right clinical setting and pharmacologic strategies that are capable of targeting the key effectors early while not inhibiting delayed repair. Early reports in a variety of disease states suggest that such pharmacologic strategies appear to have a favorable risk profile and offer substantial hope for patients.
MeSH term(s)	Complement Activation ; Complement C3a/immunology ; Complement C5a/immunology ; Humans ; Stroke/immunology ; Stroke/pathology ; Stroke/therapy ; Thrombolytic Therapy
Chemical Substances	Complement C3a (80295-42-7) ; Complement C5a (80295-54-1)
Language	English
Publishing date	2019-07-30
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2019.01723
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Spontaneous onset pseudophakic malignant glaucoma secondary to zonular weakness and cilio-lenticular block.

Wilde, Craig / Morales, Marco U / Kumudhan, Dharmalingham / Sim, Justin / Amoaku, Winfried

Oman journal of ophthalmology

2018 Volume 11, Issue 2, Page(s) 178–180

Abstract: Malignant glaucoma (MG), also known as aqueous misdirection and cilio-vitreo-lenticular block, is an infrequent cause of secondary angle closure glaucoma. Despite conventional treatment, it often has a poor visual outcome. It is recognized clinically by ... ...

Abstract	Malignant glaucoma (MG), also known as aqueous misdirection and cilio-vitreo-lenticular block, is an infrequent cause of secondary angle closure glaucoma. Despite conventional treatment, it often has a poor visual outcome. It is recognized clinically by raised intraocular pressure associated with shallowing of the peripheral and central anterior chamber in the presence of a patent peripheral iridotomy/iridectomy. Despite being known to occur after a variety of surgical procedures, it most commonly presents following filtration surgery in hypermetropic eyes with angle closure glaucoma. It can present within a range of postsurgical latencies, ranging from 1 day to many months. We describe a case of pseudophakic MG that was unusual in that it presented spontaneously many years following cataract surgery. We postulate the etiology of our spontaneous onset pseudophakic MG was the anterior subluxation of the large diameter intraocular lens secondary to zonular weakness.
Language	English
Publishing date	2018-06-08
Publishing country	India
Document type	Case Reports
ZDB-ID	2484272-2
ISSN	0974-7842 ; 0974-620X
ISSN (online)	0974-7842
ISSN	0974-620X
DOI	10.4103/ojo.OJO_34_2016
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Article ; Online: Fully Automated Segmentation Algorithm for Perihematomal Edema Volumetry After Spontaneous Intracerebral Hemorrhage.

Ironside, Natasha / Chen, Ching-Jen / Mutasa, Simukayi / Sim, Justin L / Ding, Dale / Marfatiah, Saurabh / Roh, David / Mukherjee, Sugoto / Johnston, Karen C / Southerland, Andrew M / Mayer, Stephan A / Lignelli, Angela / Connolly, Edward Sander

Stroke

2020 Volume 51, Issue 3, Page(s) 815–823

Abstract: Background and Purpose- Perihematomal edema (PHE) is a promising surrogate marker of secondary brain injury in patients with spontaneous intracerebral hemorrhage, but it can be challenging to accurately and rapidly quantify. The aims of this study are to ...

Abstract	Background and Purpose- Perihematomal edema (PHE) is a promising surrogate marker of secondary brain injury in patients with spontaneous intracerebral hemorrhage, but it can be challenging to accurately and rapidly quantify. The aims of this study are to derive and internally validate a fully automated segmentation algorithm for volumetric analysis of PHE. Methods- Inpatient computed tomography scans of 400 consecutive adults with spontaneous, supratentorial intracerebral hemorrhage enrolled in the Intracerebral Hemorrhage Outcomes Project (2009-2018) were separated into training (n=360) and test (n=40) datasets. A fully automated segmentation algorithm was derived from manual segmentations in the training dataset using convolutional neural networks, and its performance was compared with that of manual and semiautomated segmentation methods in the test dataset. Results- The mean volumetric dice similarity coefficients for the fully automated segmentation algorithm were 0.838±0.294 and 0.843±0.293 with manual and semiautomated segmentation methods as reference standards, respectively. PHE volumes derived from the fully automated versus manual (r=0.959;
MeSH term(s)	Adult ; Algorithms ; Automation ; Biomarkers ; Brain Edema/diagnostic imaging ; Brain Edema/etiology ; Cerebral Hemorrhage/complications ; Cerebral Hemorrhage/diagnostic imaging ; Female ; Hematoma/complications ; Humans ; Image Processing, Computer-Assisted ; Machine Learning ; Male ; Middle Aged ; Neuroimaging ; Tomography, X-Ray Computed ; Treatment Outcome
Chemical Substances	Biomarkers
Language	English
Publishing date	2020-02-12
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	80381-9
ISSN	1524-4628 ; 0039-2499 ; 0749-7954
ISSN (online)	1524-4628
ISSN	0039-2499 ; 0749-7954
DOI	10.1161/STROKEAHA.119.026764
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 448: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Fully Automated Segmentation Algorithm for Hematoma Volumetric Analysis in Spontaneous Intracerebral Hemorrhage.

Ironside, Natasha / Chen, Ching-Jen / Mutasa, Simukayi / Sim, Justin L / Marfatia, Saurabh / Roh, David / Ding, Dale / Mayer, Stephan A / Lignelli, Angela / Connolly, Edward Sander

Stroke

2019 Volume 50, Issue 12, Page(s) 3416–3423

Abstract: Background and Purpose- Hematoma volume measurements influence prognosis and treatment decisions in patients with spontaneous intracerebral hemorrhage (ICH). The aims of this study are to derive and validate a fully automated segmentation algorithm for ... ...

Abstract	Background and Purpose- Hematoma volume measurements influence prognosis and treatment decisions in patients with spontaneous intracerebral hemorrhage (ICH). The aims of this study are to derive and validate a fully automated segmentation algorithm for ICH volumetric analysis using deep learning methods. Methods- In-patient computed tomography scans of 300 consecutive adults (age ≥18 years) with spontaneous, supratentorial ICH who were enrolled in the ICHOP (Intracerebral Hemorrhage Outcomes Project; 2009-2018) were separated into training (n=260) and test (n=40) datasets. A fully automated segmentation algorithm was derived using convolutional neural networks, and it was trained on manual segmentations from the training dataset. The algorithm's performance was assessed against manual and semiautomated segmentation methods in the test dataset. Results- The mean volumetric Dice similarity coefficients for the fully automated segmentation algorithm when tested against manual and semiautomated segmentation methods were 0.894±0.264 and 0.905±0.254, respectively. ICH volumes derived from fully automated versus manual (
MeSH term(s)	Cerebral Hemorrhage/diagnostic imaging ; Cerebral Hemorrhage/pathology ; Deep Learning ; Hematoma/diagnostic imaging ; Hematoma/pathology ; Humans ; Image Interpretation, Computer-Assisted/methods ; Neuroimaging/methods
Language	English
Publishing date	2019-11-18
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80381-9
ISSN	1524-4628 ; 0039-2499 ; 0749-7954
ISSN (online)	1524-4628
ISSN	0039-2499 ; 0749-7954
DOI	10.1161/STROKEAHA.119.026561
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 448: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Central nervous system infection in the intensive care unit: Development and validation of a multi-parameter diagnostic prediction tool to identify suspected patients.

Andrade, Hugo Boechat / Ferreira da Silva, Ivan Rocha / Sim, Justin Lee / Mello-Neto, José Henrique / Theodoro, Pedro Henrique Nascimento / Torres da Silva, Mayara Secco / Varela, Margareth Catoia / Ramos, Grazielle Viana / Ramos da Silva, Aline / Bozza, Fernando Augusto / Soares, Jesus / Belay, Ermias D / Sejvar, James J / Cerbino-Neto, José / Japiassú, André Miguel

PloS one

2021 Volume 16, Issue 11, Page(s) e0260551

Abstract: Background: Central nervous system infections (CNSI) are diseases with high morbidity and mortality, and their diagnosis in the intensive care environment can be challenging. Objective: To develop and validate a diagnostic model to quickly screen ... ...

Abstract	Background: Central nervous system infections (CNSI) are diseases with high morbidity and mortality, and their diagnosis in the intensive care environment can be challenging. Objective: To develop and validate a diagnostic model to quickly screen intensive care patients with suspected CNSI using readily available clinical data. Methods: Derivation cohort: 783 patients admitted to an infectious diseases intensive care unit (ICU) in Oswaldo Cruz Foundation, Rio de Janeiro RJ, Brazil, for any reason, between 01/01/2012 and 06/30/2019, with a prevalence of 97 (12.4%) CNSI cases. Validation cohort 1: 163 patients prospectively collected, between 07/01/2019 and 07/01/2020, from the same ICU, with 15 (9.2%) CNSI cases. Validation cohort 2: 7,270 patients with 88 CNSI (1.21%) admitted to a neuro ICU in Chicago, IL, USA between 01/01/2014 and 06/30/2019. Prediction model: Multivariate logistic regression analysis was performed to construct the model, and Receiver Operating Characteristic (ROC) curve analysis was used for model validation. Eight predictors-age <56 years old, cerebrospinal fluid white blood cell count >2 cells/mm3, fever (≥38°C/100.4°F), focal neurologic deficit, Glasgow Coma Scale <14 points, AIDS/HIV, and seizure-were included in the development diagnostic model (P<0.05). Results: The pool data's model had an Area Under the Receiver Operating Characteristics (AUC) curve of 0.892 (95% confidence interval 0.864-0.921, P<0.0001). Conclusions: A promising and straightforward screening tool for central nervous system infections, with few and readily available clinical variables, was developed and had good accuracy, with internal and external validity.
MeSH term(s)	Adult ; Aged ; Brazil ; Central Nervous System Infections/diagnosis ; Chicago ; Critical Care ; Female ; Glasgow Coma Scale ; Humans ; Intensive Care Units ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Prognosis ; ROC Curve ; Retrospective Studies
Language	English
Publishing date	2021-11-29
Publishing country	United States
Document type	Journal Article ; Observational Study
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0260551
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Comparison of Radial Versus Femoral Access for Neuroendovascular Procedures in Very High Body Mass Index Individuals.

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Article: Predicting Chronic Subdural Hematoma Resolution and Time to Resolution Following Surgical Evacuation.

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Article ; Online: Therapeutic Modulation of the Complement Cascade in Stroke.

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Article: Spontaneous onset pseudophakic malignant glaucoma secondary to zonular weakness and cilio-lenticular block.

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Article ; Online: Fully Automated Segmentation Algorithm for Perihematomal Edema Volumetry After Spontaneous Intracerebral Hemorrhage.

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Article ; Online: Fully Automated Segmentation Algorithm for Hematoma Volumetric Analysis in Spontaneous Intracerebral Hemorrhage.

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In stock of ZB MED Cologne/Königswinter

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Article ; Online: Central nervous system infection in the intensive care unit: Development and validation of a multi-parameter diagnostic prediction tool to identify suspected patients.

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Kategorien

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Inter-library loan at ZB MED