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Book ; Online: Media, informação e literacia: rumos e perspetivas

Simões, Rita Basílio / Marques, Maria Beatriz / Figueira, João

2020

Abstract: Media, informação e literacia: rumos e perspetivas reúne um leque diversificado de olhares e de vozes sobre a relação entre Media, Informação e Literacia, na tentativa de documentar rumos e discutir perspetivas aparentemente triunfantes no contexto ... ...

Abstract	Media, informação e literacia: rumos e perspetivas reúne um leque diversificado de olhares e de vozes sobre a relação entre Media, Informação e Literacia, na tentativa de documentar rumos e discutir perspetivas aparentemente triunfantes no contexto internacional e num horizonte interdisciplinar. No seu conjunto, esses contributos alimentam o acidentado, mas vital debate sobre o impacto das alterações sociais e tecnológicas no conceito de literacia e o lugar das literacias nas sociedades democráticas
Size	1 electronic resource (602 pages)
Publisher	Coimbra University Press
Document type	Book ; Online
Note	Portuguese ; Open Access
HBZ-ID	HT020678664
ISBN	9789892618906 ; 9892618904
DOI	10.14195/978-989-26-1891-3
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Online: Pessoas e Ideias em Trânsito: Percursos e Imaginários

Simões, Rita Basílio / Serrano, Clara / Neto, Sérgio / Miranda, João

2017

Size	1 electronic resource ( pages)
Publisher	Coimbra University Press
Document type	Book ; Online
Note	Open Access
HBZ-ID	HT020589284
ISBN	9789892613628 ; 9892613627
DOI	10.14195/978-989-26-1362-8
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Online: Justiça e Comunicação: o diálogo (im)possível ("Justice and communication: the (im)possible dialogue")

Simões, Rita Basílio / Camponez, Carlos / Peixinho, Ana Teresa

2013

Abstract: The growing porosity of the boundaries between the justice system and the media should be considered with reference to the demands of the present age. It is difficult for contemporary societies to deal with a justice system that is closed in upon itself ... ...

Abstract	The growing porosity of the boundaries between the justice system and the media should be considered with reference to the demands of the present age. It is difficult for contemporary societies to deal with a justice system that is closed in upon itself and oriented by a strict rationality. They demand more scrutiny of judicial decisions, clearer and more transparent discursive practices, and more accountability to the public and the media. However, these societies do not have any structure for mediating social reality and the formation of communicative opinion, which means that the communicational exchanges that take place in the various fields of collective life are amplified by being managed within a broad public area and used to construct a multiplicity of relations.ALT_QUEBRA_LINHADespite the areas of tension involved, the justice system and the media are, we believe, in a position to foster a better understanding, not only on a normative level, given the public responsibilities accruing to both institutions in contemporary democracies, but also empirically, as this book attempts to show. In fact, by stimulating reflection about the boundaries that join and separate the different levels of formal public deliberation, as represented by the courts, and the informal level represented by the media, this collection of texts manages to redeem the traditional theorization in this domain from a revived scepticism
Size	1 electronic resource (197 pages)
Publisher	Coimbra University Press
Document type	Book ; Online
Note	Open Access
HBZ-ID	HT020589210
ISBN	9789892605401 ; 9892605403
DOI	10.14195/978-989-26-0770-2
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Insights into cork weathering regarding colour, chemical and cellular changes in view of outdoor applications.

Miranda, Isabel / Lourenço, Ana / Simões, Rita / Athayde, João / Pereira, Helena

PloS one

2024 Volume 19, Issue 4, Page(s) e0301384

Abstract: A comprehensive analysis of outdoor weathering and soil burial of cork during 1-year experiments was carried out with measurements of CIELAB color parameters, cellular observations by scanning electron microscopy, and surface chemical features analysed ... ...

Abstract	A comprehensive analysis of outdoor weathering and soil burial of cork during 1-year experiments was carried out with measurements of CIELAB color parameters, cellular observations by scanning electron microscopy, and surface chemical features analysed by ATR-FTIR and wet chemical analysis. Cork applied in outdoor conditions above and below ground retained its physical structure and integrity without signs of deterioration or fracturing. The cellular structure was maintained with some small changes at the one-cell layer at the surface, featuring cellular expansion and minute cell wall fractures. Surface color and chemistry showed distinct results for outdoor exposure and soil burial. The weathered cork surfaces acquired a lighter color while the soil buried cork surfaces became darker. With outdoor weathering, the cork polar solubles increased (13.0% vs. 7.6% o.d. mass) while a substantial decrease of lignin occurred (about 28% of the original lignin was removed) leading to a suberin-enriched cork surface. The chemical impact on lignin is therefore responsible for the surface change towards lighter colors. Soil-burial induced hydrolysis of ester bonds of suberin and xylan, and the lignin-enriched cork surface displayed a dark brown color. FTIR and wet chemical results were consistent. Overall cork showed a considerable structural and physical stability that allows its application in outdoor conditions, namely for building façades or other surfacing applications. Architects and designers should take into account the color dynamics of the cork surfaces.
MeSH term(s)	Lignin/chemistry ; Color ; Weather ; Soil
Chemical Substances	Lignin (9005-53-2) ; Soil
Language	English
Publishing date	2024-04-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0301384
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Cuticular Waxes and Cutin in

Pereira, Helena / Simões, Rita / Miranda, Isabel

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 17

Abstract: This study presents for the first time an analysis of the content and chemical composition of the cuticular waxes and cutin in the leaves of the widespread and important tropical ... ...

Abstract	This study presents for the first time an analysis of the content and chemical composition of the cuticular waxes and cutin in the leaves of the widespread and important tropical species
MeSH term(s)	Terminalia ; Sao Tome and Principe ; Plant Leaves ; Fatty Acids
Chemical Substances	cutin (54990-88-4) ; Fatty Acids
Language	English
Publishing date	2023-08-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28176365
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Deep learning-based tools to distinguish plan-specific from generic deviations in EPID-based in vivo dosimetry.

Olaciregui-Ruiz, Igor / Simões, Rita / Jan-Jakob, Sonke

Medical physics

2023 Volume 51, Issue 2, Page(s) 854–869

Abstract: Background: Dose distributions calculated with electronic portal imaging device (EPID)-based in vivo dosimetry (EIVD) differ from planned dose distributions due to generic and plan-specific deviations. Generic deviations are characteristic to a class of ...

Abstract	Background: Dose distributions calculated with electronic portal imaging device (EPID)-based in vivo dosimetry (EIVD) differ from planned dose distributions due to generic and plan-specific deviations. Generic deviations are characteristic to a class of plans. Examples include limitations in EIVD dose reconstruction, inaccuracies in treatment planning system (TPS) calculations and systematic machine deviations. Plan-specific deviations have an unpredictable character. Examples include discrepancies between the patient model used for dose calculation and the patient position or anatomy during delivery, random machine deviations, and data transfer, human or software errors. During the inspection work performed with traditional γ-evaluation statistical methods: (i) generic deviations raise alerts that need to be inspected but that rarely lead to action as their root cause is usually understood and (ii) the detection of relevant plan-specific deviations may be hindered by the presence of generic deviations. Purpose: To investigate whether deep learning-based tools can help in identifying γ-alerts raised by generic deviations and in improving the detectability of plan-specific deviations. Methods: A 3D U-Net was trained as an autoencoder to reconstruct underlying patterns of generic deviations in γ-distributions. The network was trained for four treatment disease sites differently affected by generic deviations: volumetric modulated arc therapy (VMAT) lung (no known deviations), VMAT prostate (TPS inaccuracies), VMAT head-and-neck (EIVD limitations) and intensity modulated radiation therapy (IMRT) breast (large EIVD limitations). The network was trained with virtual non-transit γ-distributions: 60 train/10 validation for the VMAT sites and 30 train/10 validation for IMRT breast. It was hypothesized that in vivo γ-distributions obtained in the presence of plan-specific deviations would differ from those seen during training. For each disease site, the sensitivity of γ-analysis and the network to detect (synthetically introduced) patient-related deviations was compared by receiver operator characteristic analysis. The investigated deviations were patient positioning errors, weight gain or loss, and tumor volume changes. The clinical relevance was illustrated qualitatively with 793 in vivo clinical cases (141 lung, 136 head-and-neck, 209 prostate and 307 breast). Results: Error detectability of patient-related deviations was better with the network than with γ-analysis. The average area under the curve values over all sites were 0.86 ± 0.12(1SD) and 0.69 ± 0.25(1SD), respectively. Regarding in vivo clinical results, the percentage of cases differently classified by γ-analysis and the network was 1%, 19%, 18% and 64% for lung, head-and-neck, prostate, and breast, respectively. In head-and-neck and breast cases, 45 γ-only alerts were examined, of which 43 were attributed to EPID dose reconstruction limitations. For prostate, all 15 investigated γ-only alerts were due to known TPS inaccuracies. All 59 investigated network alerts were explained by either patient-related deviations or EPID acquisition incidents. Some patient-related deviations detected by the network were not detected by γ-analysis. Conclusions: Deep learning-based tools trained to reconstruct underlying patterns of generic deviations in γ-distributions can be used to (i) automatically identify false positives within the set of γ-alerts and (ii) improve the detection of plan-specific deviations, hence minimizing the likelihood of false negatives. The presented method provides clear additional value to the γ-alert management process for large scale EIVD systems.
MeSH term(s)	Male ; Humans ; Radiotherapy Planning, Computer-Assisted/methods ; Radiometry ; In Vivo Dosimetry ; Deep Learning ; Radiotherapy Dosage ; Radiotherapy, Intensity-Modulated/methods
Language	English
Publishing date	2023-12-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	188780-4
ISSN	2473-4209 ; 0094-2405
ISSN (online)	2473-4209
ISSN	0094-2405
DOI	10.1002/mp.16895
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Choosing the right questions - A systematic review of patient reported outcome measures used in radiotherapy and proton beam therapy.

Fairweather, Danielle / Taylor, Rachel M / Simões, Rita

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

2023 Volume 191, Page(s) 110071

Abstract: The implementation of PROMs into clinical practice has been shown to improve quality of care. This systematic review aims to identify which PROMs are suitable for implementation within routine clinical practice in a radiotherapy or PBT service.The ... ...

Abstract	The implementation of PROMs into clinical practice has been shown to improve quality of care. This systematic review aims to identify which PROMs are suitable for implementation within routine clinical practice in a radiotherapy or PBT service.The bibliographic databases MEDLINE, EMBASE and EMCARE were searched. Articles published between 1st January 2008 to 1st June 2023, that reported PROMs being utilised as an outcome measure were included. Inclusion criteria also included being written in English, involving human patients, aged 16 and above, receiving external beam radiotherapy or PBT for six defined tumour sites. PROMs identified within the included articles were subjected to quality assessment using the COSMIN reporting guidelines. Results are reported as per PRISMA guidelines. A total of 268 studies were identified in the search, of which 52 fulfilled the inclusion criteria. The use of 39 different PROMs was reported. The PROMs identified were mostly tumour or site-specific quality of life (n = 23) measures but also included generic cancer (n = 3), health-related quality-of-life (n = 6), and symptom specific (n = 7) measures.None of the PROMs identified received a high GRADE score for good content. There were 13 PROMs that received a moderate GRADE score. The remaining PROMs either had limited evidence of development and validation within the patient cohorts investigated, or lacked relevance or comprehensiveness needed for routine PROMs collection in a radiotherapy or PBT service.This review highlights that there are a wide variety of PROMs being utilised within radiotherapy research, but most lack specificity to radiotherapy side-effects. There is a risk that by using non-specific PROMs in clinical practice, patients might not receive the supportive care that they need.
MeSH term(s)	Humans ; Proton Therapy ; Quality of Life ; Patient Reported Outcome Measures ; Neoplasms/radiotherapy ; Outcome Assessment, Health Care
Language	English
Publishing date	2023-12-22
Publishing country	Ireland
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	605646-5
ISSN	1879-0887 ; 0167-8140
ISSN (online)	1879-0887
ISSN	0167-8140
DOI	10.1016/j.radonc.2023.110071
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Variation in Leaf Cutin Content and Chemical Composition along One Annual Cycle in the Mediterranean Cork Oak (Quercus suber L.)

Simões, Rita / Miranda, Isabel / Pereira, Helena

Forests. 2023 Feb. 07, v. 14, no. 2

2023

Abstract: Cork oak (Quercus suber L.) has high economic value given by its sustainable production of cork, and ecological importance in the Mediterranean region. The species is well adapted to the dry climate, namely through the sclerophyllous nature of its leaves ...

Abstract	Cork oak (Quercus suber L.) has high economic value given by its sustainable production of cork, and ecological importance in the Mediterranean region. The species is well adapted to the dry climate, namely through the sclerophyllous nature of its leaves with a well-developed cuticle, including cutin and cuticular waxes that contribute to protection against drought. Leaves of cork oaks were collected along one annual cycle, starting from the young leaves in May to the one-year-old leaves in March. Leaf cutin content and chemical composition were determined by transesterification subsequently to the determination of cuticular waxes, and leaf features, and were analyzed along the leaf cycle. Cutin is a major component of the cuticle, representing on average 72.4% of the cutin and cuticular waxes. Cutin amounted to 71.0 g/1000 g of dry leaves, without significant seasonal mass proportion variation, while cutin coverage increased from May to December (429.7 μg/cm² and 575.4 μg/cm², respectively). In contrast, a clear seasonality was found in cuticular wax mass proportion and coverage (18.4 g/1000 g of dry leaves and 113.5 μg/cm² in May, and 28.5 g/1000 g and 235.2 μg/cm² in September). Cutin is a glyceridic polyester composed by long-chain acids, mainly ω-hydroxyacids, followed by fatty acids with a few ω-diacids and alcohols, and by a substantial proportion of aromatics. Cutin composition varied along time with a proportional increase in ω-hydroxyacids (45.8% in May; 50.8% in December), and a significant decrease in aromatics (24.2% in May and 8.5% in March). The cuticle seasonal development in the cork oak contributes to protect the leaves and the trees from the dry summer conditions.
Keywords	Quercus suber ; aromatic compounds ; chemical composition ; cork ; cutin ; drought ; dry climates ; economic valuation ; epicuticular wax ; leaves ; polyesters ; seasonal development ; summer ; transesterification ; Mediterranean region
Language	English
Dates of publication	2023-0207
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2527081-3
ISSN	1999-4907
ISSN	1999-4907
DOI	10.3390/f14020334
Database	NAL-Catalogue (AGRICOLA)

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Article: Effect of Seasonal Variation on Leaf Cuticular Waxes’ Composition in the Mediterranean Cork Oak (Quercus suber L.)

Simões, Rita / Miranda, Isabel / Pereira, Helena

Forests. 2022 Aug. 04, v. 13, no. 8

2022

Abstract: Quercus suber L. (cork oak) leaves were analyzed along one annual cycle for cuticular wax content and chemical composition. This species, well adapted to the long dry summer conditions prevailing in the Mediterranean, has a leaf life span of about one ... ...

Abstract	Quercus suber L. (cork oak) leaves were analyzed along one annual cycle for cuticular wax content and chemical composition. This species, well adapted to the long dry summer conditions prevailing in the Mediterranean, has a leaf life span of about one year. The cuticular wax revealed a seasonal variation with a coverage increase from the newly expanded leaves (115.7 µg/cm² in spring) to a maximum value in fully expanded leaves (235.6 µg/cm² after summer). Triterpenoids dominated the wax composition throughout the leaf life cycle, corresponding in young leaves to 26 µg/cm² (22.6% of the total wax) and 116.0 µg/cm² (49% of the total wax) in mature leaves, with lupeol constituting about 70% of this fraction. The total aliphatic compounds increased from 39 µg/cm² (young leaves) to 71 µg/cm² (mature leaves) and then decreased to 22 µg/cm² and slightly increased during the remaining period. The major aliphatic compounds were fatty acids, mostly with C₁₆ (hexadecanoic acid) and C₂₈ (octacosanoic acid) chain lengths. Since pentacyclic triterpenoids are located almost exclusively within the cutin matrix (intracuticular wax), the increase in the cyclic-to-acyclic component ratio after summer shows an extensive deposition of intracuticular waxes in association with the establishment of mechanical and thermal stability and of water barrier properties in the mature leaf cuticle.
Keywords	Quercus suber ; chemical composition ; cutin ; epicuticular wax ; leaves ; longevity ; lupeol ; palmitic acid ; seasonal variation ; spring ; summer ; thermal stability
Language	English
Dates of publication	2022-0804
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2527081-3
ISSN	1999-4907
ISSN	1999-4907
DOI	10.3390/f13081236
Database	NAL-Catalogue (AGRICOLA)

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Article: Cutin extraction and composition determined under differing depolymerisation conditions in cork oak leaves

Simões, Rita / Miranda, Isabel / Pereira, Helena

Phytochemical analysis. 2022 Jan., v. 33, no. 1

2022

Abstract: INTRODUCTION: Cutin is a biopolyester involved in waterproofing aerial plant organs, including leaves. Cutin quantification and compositional profiling require depolymerisation, namely by methanolysis, but specific protocols are not available. OBJECTIVES: ...

Abstract	INTRODUCTION: Cutin is a biopolyester involved in waterproofing aerial plant organs, including leaves. Cutin quantification and compositional profiling require depolymerisation, namely by methanolysis, but specific protocols are not available. OBJECTIVES: Investigate how different methanolysis conditions regarding catalyst concentration effect cutin depolymerisation and monomer release, to better define protocols for cutin content determination and composition profiling. MATERIAL AND METHODS: Cork oak (Quercus suber) dewaxed leaves were reacted with five sodium methoxide (NaOMe) concentrations. Extracts were analysed: glycerol by high‐performance liquid chromatography (HPLC) and long‐chain lipids by gas chromatography–mass spectrometry (GC–MS). RESULTS: Cutin was completely removed by 3% NaOMe (8.4% of dewaxed leaves), while mild 0.1% and 0.01% NaOMe methanolysis only depolymerised 14% of total cutin. Reactivity of cutin ester bonds is not homogeneous and glyceridic ester bonds are more easily cleaved, releasing the existing glycerol already under the mildest conditions (0.53% with 0.01% NaOMe and 0.41% with 3% NaOMe). The composition of cutin extracts varies with depolymerisation extent, with easier release of alkanoic acids and alkanols, respectively, 34.9% and 8.8% of total monomers at 0.1% NaOMe, while ω‐hydroxyacids (49.3% of total monomers) and α,ω‐diacids (9.0% of the monomers) are solubilised under more intensive reactive conditions. CONCLUSION: Cutin of Quercus suber leaves is confirmed as a glyceridic polyester of ω‐hydroxyacids and alkanoic acids, with minor content of α,ω‐diacids, and including coumarate moieties. The protocol for the determination of cutin content and compositional profiling was established regarding catalyst concentration. The molar composition of cutin suggests a macromolecular assembly based on glycerol linked to lipid oligomeric chains with moderate cross‐linking.
Keywords	Quercus suber ; biopolyesters ; catalysts ; crosslinking ; cutin ; depolymerization ; gas chromatography-mass spectrometry ; glycerol ; high performance liquid chromatography ; lipids ; methanolysis ; phytochemicals ; sodium ; solubilization
Language	English
Dates of publication	2022-01
Size	p. 127-135.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	1073576-8
ISSN	1099-1565 ; 0958-0344
ISSN (online)	1099-1565
ISSN	0958-0344
DOI	10.1002/pca.3075
Database	NAL-Catalogue (AGRICOLA)

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