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  1. AU="Simi Jacob"
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  1. Article ; Online: Streptomyces sp. RP1A-12 mediated control of peanut stem rot caused by Sclerotium rolfsii

    Simi Jacob / Ramgopal Rao Sajjalaguddam / Hari Kishan Sudini

    Journal of Integrative Agriculture, Vol 17, Iss 4, Pp 892-

    2018  Volume 900

    Abstract: Sclerotium rolfsii Sacc. is a destructive soilborne fungal pathogen with a wide host range that includes peanuts. Biological control offers an interesting alternative to fungicides for sustainable management of soilborne diseases. The current ... ...

    Abstract Sclerotium rolfsii Sacc. is a destructive soilborne fungal pathogen with a wide host range that includes peanuts. Biological control offers an interesting alternative to fungicides for sustainable management of soilborne diseases. The current investigation is aimed at evaluating one potential biocontrol agent Streptomyces sp. RP1A-12 for growth promotion and the management of peanut stem rot disease caused by S. rolfsii under field conditions. Preliminary studies conducted under in vitro and the greenhouse conditions showed promising results against the stem rot pathogen. Further in vitro and pot experiments conducted to assess Streptomyces sp. RP1A-12 for its growth promoting abilities using whole organisms have shown an increase in seed germination, root and shoot length. Other parameters like nodule number and plant biomass were also significantly increased over control treatments indicating that the test bioagent possesses growth promoting abilities along with disease suppression capabilities. Subsequently field studies were carried out for two consecutive rainy seasons. The bioagent was applied as whole organism and partially purified crude metabolites. Results indicate the bioagent reduced stem rot disease incidence by 64–67% and 22–49% respectively in two field trials conducted with notable increase in yield. Partially purified Streptomyces sp. RP1A-12 metabolites exhibited an even greater effect in reducing the incidence and severity of stem rot compared to the pathogen inoculated control.
    Keywords peanut ; stem rot ; Sclerotium rolfsii ; Streptomyces sp ; crude metabolites ; Agriculture (General) ; S1-972
    Subject code 630
    Language English
    Publishing date 2018-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Evaluation of In-vitro Anthelminthic Activity of Catharanthus roseus Extract

    Swati Agarwal / Simi Jacob / Nikkita Chettri / Saloni Bisoyi / Ayesha Tazeen / A. B. Vedamurthy / V. Krishna / H. Joy Hoskeri

    International Journal of Pharmaceutical Sciences and Drug Research, Vol 3, Iss 3, Pp 211-

    2011  Volume 213

    Abstract: Helminthes infections are chronic illnesses in human beings and in cattle. Pherithema posthuma a helminthes is commonly known as earth-worms. Although the use of alternate drugs has been as a remedial measure against the resistant strains of helminth ... ...

    Abstract Helminthes infections are chronic illnesses in human beings and in cattle. Pherithema posthuma a helminthes is commonly known as earth-worms. Although the use of alternate drugs has been as a remedial measure against the resistant strains of helminth parasites, and as a means of reducing the cost of controlling helminthic diseases. Catharanthus roseus is a medicinally valuable plant and possess various pharmacological properties. Catharanthus roseus has been traditionally used as an anthelminthic agent. To justify the ethnomedical claims, the anthelminthic property of Catharanthus roseus was evaluated using Pherithema posthuma as an experimental model. Piperazine citrate was used as the standard reference. Among the various concentrations tested, ethanol extract at 200 mg/ml showed efficient paralysis effect (6.67 min) than other treated groups, whereas ethanol extract 250 mg/ml showed significant anthelminthic activity with death time of 46.33 min. Standard drug at 50 mg/ml showed paralysis at 31.33 min and death time was 40.67 min. This investigation revealed that ethanol extract of Catharanthus roseus showed significant anthelminthic activity against Pheretima posthuma. Ethanol extract also proved to be efficient than the standard drug. This investigation supported the ethnomedical claims of Catharanthus roseus as an anthelminthic plant.
    Keywords Apocynaceae ; Catharanthus roseus ; anthelminthic activity ; Pheretima posthuma ; ethanol extract ; Therapeutics. Pharmacology ; RM1-950 ; Medicine ; R
    Subject code 630
    Language English
    Publishing date 2011-07-01T00:00:00Z
    Publisher International Journal of Pharmaceutical Sciences and Drug Research
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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