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  1. Book ; Online ; E-Book: Integrated diabetes care

    Simmons, David / Wenzel, Helmut / Zgibor, Janice C.

    a multidisciplinary approach

    2017  

    Author's details David Simmons, Helmut Wenzel, Janice C. Zgibor editors
    Language English
    Size 1 Online-Ressoure (xiii, 250 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019157353
    ISBN 978-3-319-13389-8 ; 9783319133881 ; 3-319-13389-6 ; 3319133888
    DOI 10.1007/978-3-319-13389-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Adverse pregnancy outcomes in women with type 1 or type 2 diabetes.

    Simmons, David

    The lancet. Diabetes & endocrinology

    2021  Volume 9, Issue 3, Page(s) 129–131

    MeSH term(s) Cohort Studies ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes, Gestational ; Female ; Humans ; Pregnancy ; Pregnancy Outcome/epidemiology ; Pregnancy in Diabetics/epidemiology ; Pregnant Women
    Language English
    Publishing date 2021-01-28
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2213-8595
    ISSN (online) 2213-8595
    DOI 10.1016/S2213-8587(20)30427-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Paradigm Shifts in the Management of Diabetes in Pregnancy: The Importance of Type 2 Diabetes and Early Hyperglycemia in Pregnancy: The 2020 Norbert Freinkel Award Lecture.

    Simmons, David

    Diabetes care

    2021  Volume 44, Issue 5, Page(s) 1075–1081

    Abstract: For over 50 years, the diagnosis of gestational diabetes mellitus (GDM) has been based upon an oral glucose tolerance test at 24-28 weeks' gestation. This is the time during pregnancy when insulin resistance is increasing and hyperglycemia develops among ...

    Abstract For over 50 years, the diagnosis of gestational diabetes mellitus (GDM) has been based upon an oral glucose tolerance test at 24-28 weeks' gestation. This is the time during pregnancy when insulin resistance is increasing and hyperglycemia develops among those with insufficient insulin secretory capacity to maintain euglycemia. The Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study and the two major randomized controlled trials of treating GDM are based upon recruitment of women at this time during pregnancy. Meanwhile, the increasing prevalence of type 2 diabetes in pregnancy, with its significant risk of adverse pregnancy outcomes, has led to a need to identify undiagnosed diabetes as near to conception as possible. Screening for undiagnosed diabetes early in pregnancy also identifies women with hyperglycemia less than overt diabetes, yet at increased risk of adverse pregnancy outcomes. Such women are more insulin resistant-with higher blood pressure, triglycerides, perinatal mortality, and neonatal hypoglycemia with a greater need for insulin treatment-than those with GDM diagnosed at 24-28 weeks' gestation. Currently, there is uncertainty over how to diagnose GDM early in pregnancy and the benefits and harms from using the current management regimen. Randomized controlled trials testing the criteria for, and treatment of, GDM early in pregnancy are urgently needed to address this existing equipoise. In the meantime, the importance of early or "prevalent GDM" (i.e., mild hyperglycemia present from early [before] pregnancy) warrants interim criteria and thresholds for medication, which may differ from those in use for GDM diagnosed at 24-28 weeks' gestation.
    MeSH term(s) Female ; Humans ; Infant, Newborn ; Pregnancy ; Awards and Prizes ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes, Gestational/diagnosis ; Glucose Tolerance Test ; Hyperglycemia/diagnosis ; Hyperglycemia/drug therapy ; Pregnancy Outcome ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2021-04-27
    Publishing country United States
    Document type Journal Article ; Lecture ; Research Support, Non-U.S. Gov't
    ZDB-ID 441231-x
    ISSN 1935-5548 ; 0149-5992
    ISSN (online) 1935-5548
    ISSN 0149-5992
    DOI 10.2337/dci20-0055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Modernizing medicine in Zimbabwe

    Simmons, David S.

    HIV/AIDS and traditional healers

    2012  

    Author's details David S. Simmons
    Keywords Traditional medicine ; Healers ; Medical anthropology ; HIV infections ; AIDS (Disease)
    Subject code 614.5/993920096891
    Language English
    Size XII, 224 S. : Ill.
    Edition 1. print.
    Publisher Vanderbilt Univ. Press
    Publishing place Nashville
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT017151197
    ISBN 978-0-8265-1807-1 ; 0-8265-1807-9
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: The new gestational diabetes: Treatment, evidence and consent.

    Simmons, David

    The Australian & New Zealand journal of obstetrics & gynaecology

    2020  Volume 60, Issue 5, Page(s) 816–817

    MeSH term(s) Diabetes, Gestational ; Female ; Glucose Tolerance Test ; Humans ; Informed Consent ; Pregnancy
    Language English
    Publishing date 2020-09-14
    Publishing country Australia
    Document type Letter ; Comment
    ZDB-ID 390815-x
    ISSN 1479-828X ; 0004-8666
    ISSN (online) 1479-828X
    ISSN 0004-8666
    DOI 10.1111/ajo.13233
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The benefits of the use of the new International Association of Diabetes in Pregnancy Study Groups guidelines for gestational diabetes mellitus.

    Simmons, David

    The Australian & New Zealand journal of obstetrics & gynaecology

    2020  Volume 60, Issue 3, Page(s) 486–488

    MeSH term(s) Diabetes, Gestational/diagnosis ; Female ; Glucose Tolerance Test ; Humans ; Practice Guidelines as Topic ; Pregnancy
    Language English
    Publishing date 2020-06-06
    Publishing country Australia
    Document type Editorial
    ZDB-ID 390815-x
    ISSN 1479-828X ; 0004-8666
    ISSN (online) 1479-828X
    ISSN 0004-8666
    DOI 10.1111/ajo.13167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The benefits of the use of the new International Association of Diabetes in Pregnancy Study Groups guidelines for Gestational Diabetes Mellitus.

    Simmons, David

    The Australian & New Zealand journal of obstetrics & gynaecology

    2020  Volume 60, Issue 5, Page(s) E17

    MeSH term(s) Diabetes, Gestational ; Female ; Humans ; Pregnancy
    Language English
    Publishing date 2020-10-12
    Publishing country Australia
    Document type Letter ; Comment
    ZDB-ID 390815-x
    ISSN 1479-828X ; 0004-8666
    ISSN (online) 1479-828X
    ISSN 0004-8666
    DOI 10.1111/ajo.13215
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Timing of gestational diabetes diagnosis: A novel precision approach to hyperglycaemia in pregnancy?

    Meek, Claire L / Simmons, David

    Diabetic medicine : a journal of the British Diabetic Association

    2023  Volume 40, Issue 11, Page(s) e15191

    MeSH term(s) Pregnancy ; Female ; Humans ; Diabetes, Gestational/diagnosis ; Hyperglycemia/diagnosis ; Hyperglycemia/prevention & control ; Pregnancy in Diabetics ; Pregnancy Outcome
    Language English
    Publishing date 2023-08-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 605769-x
    ISSN 1464-5491 ; 0742-3071 ; 1466-5468
    ISSN (online) 1464-5491
    ISSN 0742-3071 ; 1466-5468
    DOI 10.1111/dme.15191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Defining gestational diabetes: not just about cutoffs.

    Simmons, David / Sweeting, Arianne

    The lancet. Diabetes & endocrinology

    2023  Volume 11, Issue 5, Page(s) 303–304

    MeSH term(s) Pregnancy ; Female ; Humans ; Diabetes, Gestational/diagnosis
    Language English
    Publishing date 2023-03-31
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2213-8595
    ISSN (online) 2213-8595
    DOI 10.1016/S2213-8587(23)00092-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Glass formation and dynamics of model polymer films with one

    Ghanekarade, Asieh / Simmons, David S

    Soft matter

    2023  Volume 19, Issue 43, Page(s) 8413–8422

    Abstract: Polymers and other glass-forming liquids can exhibit profound alterations in dynamics in the nanoscale vicinity of interfaces, over a range appreciably exceeding that of typical interfacial thermodynamic gradients. The understanding of these dynamical ... ...

    Abstract Polymers and other glass-forming liquids can exhibit profound alterations in dynamics in the nanoscale vicinity of interfaces, over a range appreciably exceeding that of typical interfacial thermodynamic gradients. The understanding of these dynamical gradients is particularly complicated in systems with internal or external nanoscale dimensions, where a gradient nucleated at one interface can impinge on a second, potentially distinct, interface. To better understand the interactions that govern system dynamics and glass formation in these cases, here we simulate the baseline case of a glass-forming polymer film, over a wide range of thickness, supported on a dynamically neutral substrate that has little effect on nearby dynamics. We compare these results to our prior simulations of freestanding films. Results indicate that dynamical gradients in our simulated systems, as measured based upon translational relaxation, are simply truncated when they impinge on a secondary surface that is locally dynamically neutral. Altered film behavior can be described almost entirely by gradient effects down to the thinnest films probed, with no evidence for finite-size effects sometimes posited to play a role in these systems. Finally, our simulations predict that linear gradient overlap effects in the presence of symmetric dynamically active interfaces yield a non-monotonic variation of the whole free standing film stretching exponent (relaxation time distribution breadth). The maximum relaxation time distribution breadth in simulation is found at a film thickness of 4-5 times the interfacial gradient range. Observation of this maximum in experiment would provide an important validation that the gradient behavior observed in simulation persists to experimental timescales. If validated, observation of this maximum would potentially also enable determination of the dynamic gradient range from experimental mean-film measurements of film dynamics.
    Language English
    Publishing date 2023-11-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2191476-X
    ISSN 1744-6848 ; 1744-683X
    ISSN (online) 1744-6848
    ISSN 1744-683X
    DOI 10.1039/d3sm00719g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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