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  1. Article ; Online: Seroprevalence of Chikungunya Virus, Jamaica, and New Tools for Surveillance.

    Freitas, Andre R R / Pezzi, Laura / Cavalcanti, Luciano P G / Simon, Fabrice

    Emerging infectious diseases

    2022  Volume 28, Issue 8, Page(s) 1736–1737

    MeSH term(s) Antibodies, Viral ; Chikungunya Fever/epidemiology ; Chikungunya virus/genetics ; Dengue Virus ; Humans ; Jamaica/epidemiology ; Seroepidemiologic Studies
    Chemical Substances Antibodies, Viral
    Language English
    Publishing date 2022-07-25
    Publishing country United States
    Document type Letter
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2808.220558
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chikungunya: risks for travellers.

    Simon, Fabrice / Caumes, Eric / Jelinek, Tomas / Lopez-Velez, Rogelio / Steffen, Robert / Chen, Lin H

    Journal of travel medicine

    2023  Volume 30, Issue 2

    Abstract: Rationale for review: Chikungunya outbreaks continue to occur, with changing epidemiology. Awareness about chikungunya is low both among the at-risk travellers and healthcare professionals, which can result in underdiagnosis and underreporting. This ... ...

    Abstract Rationale for review: Chikungunya outbreaks continue to occur, with changing epidemiology. Awareness about chikungunya is low both among the at-risk travellers and healthcare professionals, which can result in underdiagnosis and underreporting. This review aims to improve awareness among healthcare professionals regarding the risks of chikungunya for travellers.
    Key findings: Chikungunya virus transmission to humans occurs mainly via daytime-active mosquitoes, Aedes aegypti and Aedes albopictus. The areas where these mosquitoes live is continuously expanding, partly due to climate changes. Chikungunya is characterized by an acute onset of fever with joint pain. These symptoms generally resolve within 1-3 weeks, but at least one-third of the patients suffer from debilitating rheumatologic symptoms for months to years. Large outbreaks in changing regions of the world since the turn of the 21st century (e.g. Caribbean, La Réunion; currently Brazil, India) have resulted in growing numbers of travellers importing chikungunya, mainly to Europe and North America. Viremic travellers with chikungunya infection have seeded chikungunya clusters (France, United States of America) and outbreaks (Italy in 2007 and 2017) in non-endemic countries where Ae. albopictus mosquitoes are present. Community preventive measures are important to prevent disease transmission by mosquitoes. Individual preventive options are limited to personal protection measures against mosquito bites, particularly the daytime-active mosquitos that transmit the chikungunya virus. Candidate vaccines are on the horizon and regulatory authorities will need to assess environmental and host risk factors for persistent sequelae, such as obesity, age (over 40 years) and history of arthritis or inflammatory rheumatologic disease to determine which populations should be targeted for these chikungunya vaccines.
    Conclusions/recommendations: Travellers planning to visit destinations with active CHIKV circulation should be advised about the risk for chikungunya, prevention strategies, the disease manifestations, possible chronic rheumatologic sequelae and, if symptomatic, seek medical evaluation and report potential exposures.
    MeSH term(s) Animals ; Humans ; Adult ; Chikungunya Fever ; Chikungunya virus ; Europe ; France ; Aedes ; Arthritis, Rheumatoid
    Language English
    Publishing date 2023-01-17
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taad008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chikungunya in U.S. Travelers: A Double Challenge.

    Simon, Fabrice / Demoux, Anne-Laurence

    The American journal of tropical medicine and hygiene

    2018  Volume 99, Issue 1, Page(s) 239

    MeSH term(s) Chikungunya Fever ; Chikungunya virus ; Dengue ; Humans ; United States
    Language English
    Publishing date 2018-07-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.18-0170
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Biodefence research: what to fund now?

    Simon, Fabrice / Savini, Hélène / Tournier, Jean-Nicolas / Ficko, Cécile

    The Lancet. Infectious diseases

    2021  Volume 21, Issue 11, Page(s) 1487–1488

    MeSH term(s) Biomedical Research ; Bioterrorism/prevention & control ; Financial Management ; Humans
    Language English
    Publishing date 2021-10-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(21)00622-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Role and Limits of COVID-19 Vaccines in the Delicate Transition from Pandemic Mitigation to Endemic Control.

    Mura, Marie / Simon, Fabrice / Pommier de Santi, Vincent / Tangy, Frédéric / Tournier, Jean-Nicolas

    Vaccines

    2022  Volume 10, Issue 9

    Abstract: The recent surge of COVID-19 related to the Omicron variant emergence has thrown a harsh light upon epidemic control in the near future. This should lead the scientific and medical community to question the long-term vaccine strategy for SARS-CoV-2 ... ...

    Abstract The recent surge of COVID-19 related to the Omicron variant emergence has thrown a harsh light upon epidemic control in the near future. This should lead the scientific and medical community to question the long-term vaccine strategy for SARS-CoV-2 control. We provide here a critical point of view regarding the virological evolution, epidemiological aspects, and immunological drivers for COVID-19 control, including a vaccination strategy. Overall, we need more innovations in vaccine development to reduce the COVID-19 burden long term. The most adequate answer might be better cooperation between universities, biotech and pharmaceutical companies.
    Language English
    Publishing date 2022-09-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10091555
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Chronic chikungunya, still to be fully understood.

    Rodríguez-Morales, Alfonso J / Simon, Fabrice

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2019  Volume 86, Page(s) 133–134

    Language English
    Publishing date 2019-07-29
    Publishing country Canada
    Document type Editorial
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2019.07.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Dengue, chikungunya and Zika and mass gatherings: What happened in Brazil, 2014.

    Gautret, Philippe / Simon, Fabrice

    Travel medicine and infectious disease

    2016  Volume 14, Issue 1, Page(s) 7–8

    MeSH term(s) Brazil/epidemiology ; Chikungunya Fever/epidemiology ; Chikungunya Fever/prevention & control ; Chikungunya Fever/virology ; Crowding ; Dengue/epidemiology ; Dengue/prevention & control ; Dengue/virology ; Disease Outbreaks ; Epidemiological Monitoring ; Humans ; Zika Virus Infection/epidemiology ; Zika Virus Infection/prevention & control ; Zika Virus Infection/virology
    Language English
    Publishing date 2016-01
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2015.12.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: What chikungunya teaches us about COVID-19.

    Simon, Fabrice / Watson, Hugh / Meynard, Jean-Baptiste / de Santi, Vincent Pommier / Tournier, Jean-Nicolas

    The Lancet. Infectious diseases

    2021  Volume 21, Issue 8, Page(s) 1070–1071

    MeSH term(s) COVID-19/complications ; Chikungunya Fever/complications ; Cost of Illness ; Humans ; SARS-CoV-2
    Language English
    Publishing date 2021-05-19
    Publishing country United States
    Document type Letter
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(21)00272-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Post-exposure prophylaxis in Ebola virus disease: don't forget the psychological factors.

    Savini, Hélène / Ficko, Cécile / Simon, Fabrice

    The Lancet. Infectious diseases

    2018  Volume 18, Issue 4, Page(s) 378

    MeSH term(s) Hemorrhagic Fever, Ebola ; Humans ; Post-Exposure Prophylaxis
    Language English
    Publishing date 2018-03-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(18)30131-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A novel framework for the treatment of arboviral diseases.

    Barnay, José-Luis / Cabie, André / Simon, Fabrice

    The Lancet. Infectious diseases

    2018  Volume 18, Issue 11, Page(s) 1178–1179

    MeSH term(s) Arbovirus Infections/epidemiology ; Disease Outbreaks ; Humans
    Language English
    Publishing date 2018-10-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(18)30572-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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