LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 261

Search options

  1. Book ; Audio / Video ; Thesis: Freiwilliges Engagement im sozialen Bereich: Motivation von Ärztinnen und Ärzten, sich in der humanitären Hilfe zu engagieren

    Aschoff, Simon Nicolas

    2020  

    Author's details vorgelegt von Simon Nicolas Aschoff
    Language German
    Size 1 CD-ROM
    Publishing place Witten/Herdecke
    Publishing country Germany
    Document type Book ; Audio / Video ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Witten/Herdecke, 2021
    HBZ-ID HT021263808
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 MO 6 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book ; Online: Légiférer, gouverner et juger : Mélanges dhistoire du droit et des institutions (ixe-xxie siècles) offerts à Jean-Marie Cauchies à loccasion de ses 65 ans

    Bousmar, Éric / Desmette, Philippe / Simon, Nicolas

    2016  

    Abstract: Membre de lAcadémie royale de Belgique, Jean-Marie Cauchies a enseigné durant près de quarante années à lUniversité Saint-Louis - Bruxelles. En lui offrant ce Liber amicorum à loccasion de son soixante-cinquième anniversaire, ses collègues ont souhaité ... ...

    Abstract Membre de lAcadémie royale de Belgique, Jean-Marie Cauchies a enseigné durant près de quarante années à lUniversité Saint-Louis - Bruxelles. En lui offrant ce Liber amicorum à loccasion de son soixante-cinquième anniversaire, ses collègues ont souhaité honorer limportance de son œuvre scientifique dans le domaine de lhistoire du droit, des institutions et de la vie politique. Ils ont aussi voulu témoigner leur reconnaissance à lanimateur dinnombrables sociétés savantes. Les contributeurs belges et européens réunis pour cet hommage livrent ici une vingtaine détudes touchant les mécanismes du gouvernement et de la législation, mais aussi la mise en œuvre de la justice, tant en France et en Italie quen Suisse, aux Pays-Bas ou en Belgique. Dans la droite ligne des centres dintérêt de Jean-Marie Cauchies qui, médiéviste, na jamais négligé dans ses travaux les périodes plus récentes, le présent ouvrage embrasse la longue durée, du Moyen Âge à nos jours. Une biographie du jubilaire et la liste de ses publications témoignent également de la diversité et de la cohérence de ses approches
    Keywords History (General)
    Size 1 electronic resource ( pages)
    Publisher Presses de l'Université Saint-Louis
    Document type Book ; Online
    Note French ; Open Access
    HBZ-ID HT020323561
    ISBN 9782802804925 ; 2802804928
    DOI 10.4000/books.pusl.3134
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: An observational study of benzodiazepine prescription during inpatient alcohol detoxification for patients with versus without chronic pretreatment with high dosage baclofen.

    Simon, Nicolas

    Fundamental & clinical pharmacology

    2018  Volume 32, Issue 2, Page(s) 198–199

    MeSH term(s) Alcoholism/rehabilitation ; Baclofen/administration & dosage ; Benzodiazepines/administration & dosage ; Dose-Response Relationship, Drug ; Humans ; Inpatients
    Chemical Substances Benzodiazepines (12794-10-4) ; Baclofen (H789N3FKE8)
    Language English
    Publishing date 2018-01-12
    Publishing country England
    Document type Editorial
    ZDB-ID 639134-5
    ISSN 1472-8206 ; 0767-3981
    ISSN (online) 1472-8206
    ISSN 0767-3981
    DOI 10.1111/fcp.12354
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2247: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Book ; Online ; Thesis: Freiwilliges Engagement im sozialen Bereich: Motivation von Ärztinnen und Ärzten, sich in der humanitären Hilfe zu engagieren

    Aschoff, Simon Nicolas [Verfasser]

    2022  

    Author's details vorgelegt von Simon Nicolas Aschoff
    Keywords Soziale Probleme, Sozialarbeit ; Social problems, Social work
    Subject code sg360
    Language German
    Publisher Leipzig ; Deutsche Nationalbibliothek
    Publishing place Frankfurt am Main
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article: Proton Pump Inhibitors and Cancer: Current State of Play.

    Bridoux, Marie / Simon, Nicolas / Turpin, Anthony

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 798272

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-03-14
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.798272
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Comorbidities and the right dose: antipsychotics.

    Simon, Nicolas / Torrents, Romain / Azorin, Jean-Michel

    Expert opinion on drug metabolism & toxicology

    2022  Volume 18, Issue 7-8, Page(s) 507–518

    Abstract: Introduction: The effects of antipsychotic drugs are dose-dependent, which is particularly true for their efficacy, each antipsychotic having a specific dose-response curve. This may justify individualizing doses for these agents.: Areas covered: We ... ...

    Abstract Introduction: The effects of antipsychotic drugs are dose-dependent, which is particularly true for their efficacy, each antipsychotic having a specific dose-response curve. This may justify individualizing doses for these agents.
    Areas covered: We review the pharmacokinetic profiles of seven oral antipsychotics: haloperidol, risperidone, olanzapine, clozapine, quetiapine, ziprasidone, and aripiprazole. Their main indications are psychotic and affective disorders. They are prescribed in a very large population which may have comorbidities. Hence, we analyze the impact of the latter on the pharmacokinetic profiles of these antipsychotics, focusing on renal and hepatic impairment. Reviews and clinical trials were discussed based on a systematic literature search (PubMed) ranging from 1995 to 2022.
    Expert opinion: Factors liable to impact antipsychotic dosage are numerous and their subsequent effects often hard to predict, due to multilevel interactions and compensatory phenomena. In clinical practice, physicians must be aware of these potential effects, but base their decisions on monitoring antipsychotic plasma levels.
    MeSH term(s) Antipsychotic Agents ; Benzodiazepines/therapeutic use ; Clozapine ; Humans ; Olanzapine ; Quetiapine Fumarate ; Risperidone/therapeutic use
    Chemical Substances Antipsychotic Agents ; Benzodiazepines (12794-10-4) ; Quetiapine Fumarate (2S3PL1B6UJ) ; Clozapine (J60AR2IKIC) ; Risperidone (L6UH7ZF8HC) ; Olanzapine (N7U69T4SZR)
    Language English
    Publishing date 2022-08-22
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 2214462-6
    ISSN 1744-7607 ; 1742-5255
    ISSN (online) 1744-7607
    ISSN 1742-5255
    DOI 10.1080/17425255.2022.2113378
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6264: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Reply to the letter to the Editor "Prediction of lopinavir/ritonavir effectiveness in COVID-19 patients: a recall of basic pharmacology concepts".

    Simon, Nicolas / Alvarez, Jean Claude

    European journal of clinical pharmacology

    2020  Volume 77, Issue 5, Page(s) 793–794

    MeSH term(s) Antiviral Agents/therapeutic use ; COVID-19/drug therapy ; Humans ; Lopinavir ; Ritonavir ; SARS-CoV-2
    Chemical Substances Antiviral Agents ; Lopinavir (2494G1JF75) ; Ritonavir (O3J8G9O825)
    Language English
    Publishing date 2020-11-26
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 121960-1
    ISSN 1432-1041 ; 0031-6970
    ISSN (online) 1432-1041
    ISSN 0031-6970
    DOI 10.1007/s00228-020-03056-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 672: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Antipsychotic polypharmacy in schizophrenia: evolving evidence and rationale.

    Azorin, Jean-Michel / Simon, Nicolas

    Expert opinion on drug metabolism & toxicology

    2020  Volume 16, Issue 12, Page(s) 1175–1186

    Abstract: Introduction: Antipsychotic polypharmacy (APP), defined as the use of more than one antipsychotic, is common in schizophrenia. However, current guidelines consider that the level of evidence to support APP is weak and mostly recommend monotherapy.: ... ...

    Abstract Introduction: Antipsychotic polypharmacy (APP), defined as the use of more than one antipsychotic, is common in schizophrenia. However, current guidelines consider that the level of evidence to support APP is weak and mostly recommend monotherapy.
    Areas covered: Meta-analyses of randomized controlled trials (RCTs) on the efficacy and tolerability of APP, effectiveness studies on its use in clinical practice, as well as theoretical models liable to legitimate this use are reviewed and discussed on the basis of a systematic literature search (PubMed) ranging from 1995 to 2020.
    Expert opinion: There is now increasing evidence from both efficacy and effectiveness studies, that APP may be beneficial for some schizophrenia patients. The most evidence seems to be for the combination of clozapine and aripiprazole. The choice of this combination may fit in well with the dopamine supersensitivity hypothesis in schizophrenia. Guidelines should be revised, but further studies are needed to confirm the efficacy/effectiveness of this combination, especially in the case of first-episode schizophrenia.
    MeSH term(s) Antipsychotic Agents/administration & dosage ; Antipsychotic Agents/adverse effects ; Aripiprazole/administration & dosage ; Clozapine/administration & dosage ; Drug Therapy, Combination ; Humans ; Models, Theoretical ; Polypharmacy ; Practice Guidelines as Topic ; Randomized Controlled Trials as Topic ; Schizophrenia/drug therapy
    Chemical Substances Antipsychotic Agents ; Aripiprazole (82VFR53I78) ; Clozapine (J60AR2IKIC)
    Language English
    Publishing date 2020-09-28
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2214462-6
    ISSN 1744-7607 ; 1742-5255
    ISSN (online) 1744-7607
    ISSN 1742-5255
    DOI 10.1080/17425255.2020.1821646
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6264: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Profile of serious angioedema requiring an urgent advice from a national reference call center.

    Simon, Nicolas / Bocquet, Alexis / Boccon-Gibod, Isabelle / Bouillet, Laurence

    Medicine

    2022  Volume 101, Issue 31, Page(s) e29513

    Abstract: Angioedema (AE) is a reason for emergency care when it is severe. Care is difficult when the diagnostic is not known before the attack: mast cell (MC) or bradykinin (BK) mediated. One is very common but often benign, the other rare but potentially fatal. ...

    Abstract Angioedema (AE) is a reason for emergency care when it is severe. Care is difficult when the diagnostic is not known before the attack: mast cell (MC) or bradykinin (BK) mediated. One is very common but often benign, the other rare but potentially fatal. The French national reference center of angioedema (CREAK) provides emergency physicians with a hotline and a guideline to help them manage their patients. This study aimed to describe the clinical features of AE episodes prompting a call on the CREAK hotline and classify patients depending on the suspected cause of the AE. This is a retrospective study between March and August 2019. Each physician calling on the CREAK hotline was asked to fill a clinical description form for the AE emergency. Known patients of CREAK was excluded. Eighty four patients were included. Forty one (48.8%) in the angiotensin converting enzyme inhibitors induced acquired angioedema (ACEi-AAE), 39 (46.4%) in the mast cell induced angioedema, and 4 (4.8%) in the Bradykinin mediated angioedema. The mast cell induced angioedema patients have more history of hives (29.3%) than ACEi-AAE (2.4%, P = .0004). ACEi-AAE mainly affected the tongue (58.5% vs 25.6%, P = .003) and larynx (29.3% vs 13%, P = .001). In 65.5% of cases, the etiological diagnosis was not mentioned by the appellant, but made by the hotline. In 31% of cases, the hotline suggested the administration of a specific treatment not previously provided by the caller. All the doctors who called the hotline appreciate this tele-expertise especially in case of ACEi-AAE presumptions. In addition to providing rapid AE expertise, this service also allows to educate physicians in the management of AE irrespective of its origin.
    MeSH term(s) Angioedema/diagnosis ; Angioedema/etiology ; Angioedema/therapy ; Bradykinin/therapeutic use ; Call Centers ; Humans ; Retrospective Studies
    Chemical Substances Bradykinin (S8TIM42R2W)
    Language English
    Publishing date 2022-08-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000029513
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.171: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Four-year follow-up of surface contamination by antineoplastic drugs in a compounding unit.

    Saint-Lorant, Guillaume / Vasseur, Michèle / Allorge, Delphine / Beauval, Nicolas / Simon, Nicolas / Odou, Pascal

    Occupational and environmental medicine

    2023  Volume 80, Issue 3, Page(s) 146–153

    Abstract: Objectives: This study aimed to monitor the contamination by antineoplastic drugs on work surfaces in a compounding unit 4 years after its implementation.: Methods: This descriptive study was done in a unit performing on average 45 000 preparations ... ...

    Abstract Objectives: This study aimed to monitor the contamination by antineoplastic drugs on work surfaces in a compounding unit 4 years after its implementation.
    Methods: This descriptive study was done in a unit performing on average 45 000 preparations per year. Surface sampling points (N=23) were monitored monthly in the frame of routine activity from the opening of an anticancer drug compounding unit. Contamination with nine antineoplastic drugs (cyclophosphamide, ifosfamide, dacarbazine, 5-fluorouracil, methotrexate, gemcitabine, cytarabine, irinotecan and doxorubicin) was assessed on wipes with a local liquid chromatography coupled with a tandem mass spectrometer analysis. The contamination rate (CR, %) was prospectively monitored every month during the entire study period. The occurrence of critical incidents was also registered. The effect of each safety measure implemented during this period was also analysed.
    Results: Based on the 1104 samples collected between March 2016 and March 2020, the CR was 18.5%. If three different critical incidents among a vial breakage that occurred were individually considered, this CR was slightly lower than that in the literature. Eight months after opening and taking different corrective actions, the overall CR dropped from 42.39% to 11.52% (p<0.001). Contamination was limited to the area that includes the compounding room and, more precisely, the welder and the QC-Prep
    Conclusions: From the beginning of the study and from month to month, surface contamination was limited to the nearest sampling points to the compounding unit. This 4-year monitoring study allowed us to determine the intravenous conventional antineoplastic drugs and sampling points to be focused on.
    MeSH term(s) Humans ; Follow-Up Studies ; Antineoplastic Agents/analysis ; Antineoplastic Agents/chemistry ; Cyclophosphamide/adverse effects ; Cyclophosphamide/analysis ; Ifosfamide/analysis ; Fluorouracil/analysis ; Occupational Exposure/adverse effects ; Occupational Exposure/analysis ; Environmental Monitoring/methods
    Chemical Substances Antineoplastic Agents ; Cyclophosphamide (8N3DW7272P) ; Ifosfamide (UM20QQM95Y) ; Fluorouracil (U3P01618RT)
    Language English
    Publishing date 2023-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1180733-7
    ISSN 1470-7926 ; 1351-0711
    ISSN (online) 1470-7926
    ISSN 1351-0711
    DOI 10.1136/oemed-2022-108623
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Un I Zs.461: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top