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Article: Patienten-zentrierte digitale Implantologie. Minimalinvasiv und regenerativ: Implantattherapie bei reduzierter Kieferkammbreite mit volldigitalem Workflow. Fallbericht einer Split-Mouth-Behandlung.

Raabe, Clemens / Janner, Simone F M / Abou-Ayash, Samir

2021 Volume 131, Issue 5, Page(s) 437–441

Abstract: Modern treatment protocols in implant dentistry focus on lower morbidity and patient-centered outcomes, in addition to commonly applied treatment success criteria. Prosthetically-driven digital planning followed by static computer-assisted implant ... ...

Title translation	Comprehensive Digital Workflow and Computer-Assisted Implant Surgery in a Patient with Reduced Crest Width. Case Report of a Split-Mouth Approach.
Abstract	Modern treatment protocols in implant dentistry focus on lower morbidity and patient-centered outcomes, in addition to commonly applied treatment success criteria. Prosthetically-driven digital planning followed by static computer-assisted implant surgery (sCAIS) may minimize the need for bone augmentation by ideally utilizing the residual crest and thereby improve patient satisfaction. A healthy 37-year-old female suffered from agenesis of both second mandibular premolars and presented wide single-tooth gaps on both sides of the mandible with a moderate (left) and pronounced (right) horizontal bone deficiency. 3D implant planning allowed ideal implant positioning in the residual bone volume while respecting critical anatomical structures. This enabled a flapless sCAIS procedure without bone grafting in the left mandible. On the right side, the insufficient bone volume was augmented simultaneously to the sCAIS using GBR. The clinical and radiographic parameters showed a good oral health status in the 1-year postop examination. The final implant position presented a minimal angular and horizontal deviation from the initial planning. The patient was highly satisfied with the two applied methods but preferred the flapless procedure.
MeSH term(s)	Adult ; Computers ; Dental Implantation, Endosseous ; Dental Implants ; Female ; Humans ; Mouth ; Surgery, Computer-Assisted ; Workflow
Chemical Substances	Dental Implants
Language	German
Publishing date	2021-05-05
Publishing country	Switzerland
Document type	Case Reports ; Journal Article
ZDB-ID	2754538-6
ISSN	2296-6498
ISSN	2296-6498
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Article ; Online: Inter- and intraindividual variability in virtual single-tooth implant positioning.

Raabe, Clemens / Biel, Philippe / Dulla, Fabrice A / Janner, Simone F M / Abou-Ayash, Samir / Couso-Queiruga, Emilio

Clinical oral implants research

2023

Abstract: Objectives: The purpose of this prospective study was to determine the inter- and intraindividual variability in virtual single-tooth implant positioning based on the level of expertise, specialty, total time spent, and the use of a prosthetic tooth ... ...

Abstract	Objectives: The purpose of this prospective study was to determine the inter- and intraindividual variability in virtual single-tooth implant positioning based on the level of expertise, specialty, total time spent, and the use of a prosthetic tooth setup. Materials and methods: Virtual implant planning was performed on matched pre- and post-extraction intraoral scans (IOS), and cone-beam computed tomography scans of 15 patients. Twelve individual examiners, involving six novices and experts from oral surgery and prosthodontics positioned the implants, first based on anatomical landmarks utilizing only the post-extraction, and second with the use of the pre-extraction IOS as a setup. The time for implant positioning was recorded. After 1 month, all virtual plannings were performed again. The individual implant positions were superimposed to obtain 3D deviations using a software algorithm. Results: An interindividual variability with mean angular, crestal, and apical positional deviations of 3.8 ± 1.94°, 1.11 ± 0.55, and 1.54 ± 0.66 mm, respectively, was found. When assessing intraindividual variability, deviations of 3.28 ± 1.99°, 0.78 ± 0.46, and 1.12 ± 0.61 mm, respectively, were observed. Implants planned by experts exhibited statistically lower deviations compared to those planned by novices. Longer planning times resulted in lower deviations in the experts' group but not in the novices. Oral surgeons demonstrated lower crestal, but not angular and apical deviations than prosthodontists. The use of a setup only led to minor adjustments. Conclusions: Substantial inter- and intraindividual variability exists during implant positioning utilizing specialized software planning. The level of expertise and the time invested influenced the deviations of the implant position during the planning sequence.
Language	English
Publishing date	2023-11-15
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	1067626-0
ISSN	1600-0501 ; 0905-7161
ISSN (online)	1600-0501
ISSN	0905-7161
DOI	10.1111/clr.14203
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Article: Through-and-through cystic lesion: spontaneous healing after needle aspiration and conventional root-canal therapy

von Arx, Thomas / Kissling- Jeger, Franziska B / Simone, Simone F M

Swiss dental journal

2020 Volume 130, Issue 1, Page(s) 31–35

Abstract: Inflammation-related pathologies such as apical periodontitis or radicular cysts are frequent lesions of the jawbones. Typically, a radiolucency is present that is not always distinguishable from other pathologies. A surgical approach would allow for ... ...

Title translation	Tunnelierende zystische Läsion: Spontanheilung nach Aspiration und Wurzelkanalbehandlung
Abstract	Inflammation-related pathologies such as apical periodontitis or radicular cysts are frequent lesions of the jawbones. Typically, a radiolucency is present that is not always distinguishable from other pathologies. A surgical approach would allow for tissue harvesting with further histopathologic processing. However, in the present case report of a cystic and large tunnelling lesion in the anterior maxilla, a conservative treatment with diagnostic needle aspiration and subsequent root-canal therapy was chosen. The long-term follow-up (eight years) including cone-beam computed tomography demonstrates a complete healing of the former bone defect with reestablishment of the vestibular and palatal cortices as well as absence of pain and other clinical symptoms.
MeSH term(s)	Cone-Beam Computed Tomography ; Humans ; Maxilla ; Periapical Periodontitis ; Radicular Cyst ; Root Canal Therapy
Language	German
Publishing date	2020-01-06
Publishing country	Switzerland
Document type	Case Reports ; Journal Article
ZDB-ID	2754538-6
ISSN	2296-6498
ISSN	2296-6498
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Article ; Online: Unique air inclusions within the nasopalatine duct indicating its presence radiographically: a case presentation.

von Arx, Thomas / Bornstein, Michael M / Janner, Simone F M

Surgical and radiologic anatomy : SRA

2020 Volume 42, Issue 7, Page(s) 817–821

Abstract: The anterior maxilla is characterized by the nasopalatine canal that originates bilaterally from the anterior nasal floor, subsequently fuses, and terminates at the incisive foramen in the anterior palate. Embryologically, this structure forms within the ...

Abstract	The anterior maxilla is characterized by the nasopalatine canal that originates bilaterally from the anterior nasal floor, subsequently fuses, and terminates at the incisive foramen in the anterior palate. Embryologically, this structure forms within the primary palate, and contains the neurovascular bundle, but also continuous epithelialized bands. The latter, termed nasopalatine ducts, usually degenerate and/or obliterate before birth. However, in some individuals, the ducts may remain partially or completely patent. The present case report describes for the first time in the literature a rare finding of air inclusions within the anatomical area of the nasopalatine canal indicating the presence of a nasopalatine duct as visualized with cone beam computed tomography. The patient was asymptomatic and the radiographic findings were seen incidentally. An endoscopic inspection of the anterior nasal cavities confirmed the presence of the nasal openings of the partially patent nasopalatine ducts.
MeSH term(s)	Anatomic Variation ; Cone-Beam Computed Tomography ; Endoscopy ; Female ; Humans ; Incidental Findings ; Middle Aged ; Nasal Cavity/abnormalities ; Nasal Cavity/diagnostic imaging ; Palate, Hard/abnormalities ; Palate, Hard/diagnostic imaging
Language	English
Publishing date	2020-02-10
Publishing country	Germany
Document type	Case Reports ; Journal Article
ZDB-ID	632839-8
ISSN	1279-8517 ; 0930-312X ; 0930-1038
ISSN (online)	1279-8517
ISSN	0930-312X ; 0930-1038
DOI	10.1007/s00276-020-02428-4
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Article: Bioceramic root repair material (BCRRM) for root-end obturation in apical surgery. An analysis of 174 teeth after 1 year.

von Arx, Thomas / Janner, Simone F M / Haenni, Stefan / Bornstein, Michael M

Swiss dental journal

2020 Volume 130, Issue 5, Page(s) 390–396

Abstract: The objective of this paper was the analysis of the 1-year outcome of teeth treated with apical surgery and a recently introduced bioceramic root repair material (BCRRM) for root-end filling. Patients were consecutively enrolled from 2015 to 2017. Apical ...

Abstract	The objective of this paper was the analysis of the 1-year outcome of teeth treated with apical surgery and a recently introduced bioceramic root repair material (BCRRM) for root-end filling. Patients were consecutively enrolled from 2015 to 2017. Apical surgery included the modern technique, i.e. the use of a surgical microscope, ultrasonic preparation of a root-end cavity, and retrofilling with BCRRM. The cohort comprised 150 patients with 174 treated teeth. Patients were recalled one year after surgery for a clinical and radiographic re-examination. Three experienced observers evaluated the periapical radiographs with regard to periapical healing utilizing the healing criteria established by Rud et al. (1972) and Molven et al. (1987). Based on the clinical findings and the radiographic assessment, healing was judged as successful, uncertain, or failed. Study parameters included gender, age, type of treated tooth, and type of BCRRM (regular vs. fast set putty). At the 1-year follow-up, 170 teeth could be reexamined (drop-out rate 2.3%). Healing outcome was categorized as successful in 94.1%, uncertain in 4.1%, and failed in 1.8%. No significant differences were observed when comparing the success rates among the different subcategories of study parameters. The lowest success rate was noted in mandibular premolars (86.7%) but without reaching statistical significance. In conclusion, BCRRM appears to be a biocompatible root-end filling material showing excellent 1-year results. The success rate was similar to recently reported success rates for BCRRM in apical surgery.
MeSH term(s)	Acrylic Resins ; Follow-Up Studies ; Humans ; Root Canal Filling Materials ; Root Canal Obturation ; Treatment Outcome
Chemical Substances	Acrylic Resins ; Repair Material ; Root Canal Filling Materials
Language	English
Publishing date	2020-04-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2754538-6
ISSN	2296-6498
ISSN	2296-6498
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Article ; Online: The influence of guided sleeve height, drilling distance, and drilling key length on the accuracy of static Computer-Assisted Implant Surgery.

El Kholy, Karim / Janner, Simone F M / Schimmel, Martin / Buser, Daniel

Clinical implant dentistry and related research

2018 Volume 21, Issue 1, Page(s) 101–107

Abstract: Objective: The aim of this study was to evaluate the effect of guided sleeve height, drilling distance, and guided key height on accuracy of static Computer-Assisted Implant Surgery (sCAIS).: Materials and methods: Pre and post-operative positions of ...

Abstract	Objective: The aim of this study was to evaluate the effect of guided sleeve height, drilling distance, and guided key height on accuracy of static Computer-Assisted Implant Surgery (sCAIS). Materials and methods: Pre and post-operative positions of implants placed in duplicate dental models were compared and recorded after placement of implants according to a standardized treatment planning and execution sCAIS protocol. Guided sleeve heights: 2 mm, 4 mm, 6 mm and guided key heights: 1 mm and 3 mm were equally randomized in six test groups with varying implant lengths (10-16 mm) and surgical drilling protocols. The mean crestal and apical three-dimensional (3D) deviation, as well as the angular deviation were calculated for each group. Data was analyzed using multivariate analysis anova. P values less than .05 were considered statistically significant. All P values of post-hoc tests were corrected for multiple testing using Bonferroni-Holm's adjustment method. Results: 3D implant positioning accuracy was not significantly affected by the difference in sleeve height alone or by the implant length alone (P > .05). However, 3D and angular deviation values became significantly higher as the total drilling distance below the guided sleeve increased and significantly became lower as the guided key height above the sleeve increased. 18 mm drilling distance resulted in a significantly higher deviation, when compared to 14 mm or 16 mm drilling distances, irrespective of sleeve height or implant length (P < .01). 3 mm key height resulted in significantly less 3D deviation than 1 mm key height (P < .01). Conclusion: Decreasing the drilling distance below the guided sleeve, by using shorter sleeve heights or shorter implants can significantly increase the accuracy of sCAIS.
MeSH term(s)	Dental Implantation, Endosseous/instrumentation ; Dental Implantation, Endosseous/methods ; Dental Implants ; Humans ; Surgery, Computer-Assisted/methods
Chemical Substances	Dental Implants
Language	English
Publishing date	2018-12-27
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	2094300-3
ISSN	1708-8208 ; 1523-0899
ISSN (online)	1708-8208
ISSN	1523-0899
DOI	10.1111/cid.12705
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Zs.A 5945: Show issues

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Article ; Online: A 10-year Follow-up Study of 119 Teeth Treated with Apical Surgery and Root-end Filling with Mineral Trioxide Aggregate.

von Arx, Thomas / Jensen, Simon S / Janner, Simone F M / Hänni, Stefan / Bornstein, Michael M

Journal of endodontics

2019 Volume 45, Issue 4, Page(s) 394–401

Abstract: Introduction: The objective of this clinical study was to assess the long-term outcome (clinical signs/symptoms and radiographic healing) of teeth treated with apical surgery and mineral trioxide aggregate (MTA) for root-end filling.: Methods: One ... ...

Abstract	Introduction: The objective of this clinical study was to assess the long-term outcome (clinical signs/symptoms and radiographic healing) of teeth treated with apical surgery and mineral trioxide aggregate (MTA) for root-end filling. Methods: One hundred ninety-five patients were recalled 1, 5, and 10 years after apical surgery for clinical and radiographic examinations. Three calibrated observers evaluated the periapical radiographs independently. The evolution of the cases over time was analyzed. Healing classification of teeth was divided into "healed" versus "not healed" teeth using well-established clinical and radiographic healing criteria. The potential influence of sex, age, type of treated tooth, type of MTA, and first-time versus repeat surgery on healing outcome was statistically analyzed. Results: The inception cohort included 195 teeth. The dropout rate after 10 years amounted to 39% (n = 76). Of the 119 teeth available for the 10-year analysis, 97 teeth were classified as healed (81.5%). No significant differences were found with regard to the rate of healed cases for the subcategories of the parameters of age, sex, type of MTA, and first-time or repeat surgery. Concerning the type of treated tooth, the rate of healed maxillary molars (95.2%) differed significantly (P = .035) from the rate of healed maxillary premolars (66.7%). The predictive value of the cases classified as healed at 1 year and remaining so over the 10-year observation period was 86.8%. Conclusions: This 10-year follow-up study of teeth treated with apical surgery and MTA as root-end filling material showed an acceptable rate of healed cases. Many of the lost teeth had been extracted because of longitudinal root fractures during the observation period.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Aluminum Compounds/therapeutic use ; Apicoectomy/methods ; Calcium Compounds/therapeutic use ; Child ; Cohort Studies ; Drug Combinations ; Female ; Follow-Up Studies ; Humans ; Male ; Maxilla ; Middle Aged ; Molar ; Oxides/therapeutic use ; Radiography, Dental ; Retrograde Obturation/methods ; Root Canal Filling Materials/therapeutic use ; Silicates/therapeutic use ; Time Factors ; Tooth Apex/diagnostic imaging ; Tooth Apex/surgery ; Treatment Outcome ; Young Adult
Chemical Substances	Aluminum Compounds ; Calcium Compounds ; Drug Combinations ; Oxides ; Root Canal Filling Materials ; Silicates ; mineral trioxide aggregate
Language	English
Publishing date	2019-03-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	752412-2
ISSN	1878-3554 ; 0099-2399
ISSN (online)	1878-3554
ISSN	0099-2399
DOI	10.1016/j.joen.2018.12.015
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Article ; Online: Radiographic Assessment of Bone Healing Using Cone-beam Computed Tomographic Scans 1 and 5 Years after Apical Surgery.

von Arx, Thomas / Janner, Simone F M / Hänni, Stefan / Bornstein, Michael M

Journal of endodontics

2019 Volume 45, Issue 11, Page(s) 1307–1313

Abstract: Introduction: The objective of this long-term study was to evaluate radiographic healing in cone-beam computed tomographic (CBCT) scans taken 1 and 5 years after apical surgery.: Methods: In the context of a prospective clinical study, postsurgical ... ...

Abstract	Introduction: The objective of this long-term study was to evaluate radiographic healing in cone-beam computed tomographic (CBCT) scans taken 1 and 5 years after apical surgery. Methods: In the context of a prospective clinical study, postsurgical CBCT scans were taken 1 and 5 years after apical surgery. Three calibrated observers independently assessed buccolingual CBCT images oriented along the longitudinal axis of the treated roots. Radiographic periapical healing was categorized as "fully, partially, or not healed" for each of the following study parameters: the resection plane, the cortical plate, the apical area, and the overall bone healing. The analysis included the interobserver agreement (Fleiss kappa values), the comparison of 5- and 1-year ratings, and the changes of healing categories from 1-5 years (McNemar-Bowker tests). Data were analyzed statistically for the detection of significant differences. Results: CBCT images of 41 teeth (in 41 patients) with 47 treated roots were evaluated. At 5 years, all studied parameters had higher rates of fully healed cases compared with the rate at 1 year. The resection plane and apical area parameters each were judged in 72.3% as fully healed at 5 years, whereas the cortical plate and overall bone healing parameters showed clearly lower fully healed rates (42.6% and 38.3%, respectively). Fully healed cases at 1 year remained so at 5 years in 87.5%-100% depending on the study parameter. Conclusions: This 5-year CBCT follow-up study of apical surgery showed a marked improvement of radiographic healing from 1-5 years but to a varying degree regarding the different study parameters. Although new hard tissue formation at the resection plane and within the former apical defect was advanced in most cases at 5 years, the reestablishment of the cortical bone plate clearly lagged behind.
MeSH term(s)	Cone-Beam Computed Tomography ; Follow-Up Studies ; Humans ; Periapical Diseases/surgery ; Prospective Studies ; Tomography, X-Ray Computed ; Tooth Apex/surgery
Language	English
Publishing date	2019-09-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	752412-2
ISSN	1878-3554 ; 0099-2399
ISSN (online)	1878-3554
ISSN	0099-2399
DOI	10.1016/j.joen.2019.08.008
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Article ; Online: Influence of surgical guide support and implant site location on accuracy of static Computer-Assisted Implant Surgery.

El Kholy, Karim / Lazarin, Rafael / Janner, Simone F M / Faerber, Karin / Buser, Ramona / Buser, Daniel

Clinical oral implants research

2019 Volume 30, Issue 11, Page(s) 1067–1075

Abstract: Objective: To investigate the effect of surgical guide support and implant site location on the accuracy of static Computer-Assisted Implant Surgery (sCAIS) in partially edentulous patients.: Materials and methods: 375 replica implants were inserted ... ...

Abstract	Objective: To investigate the effect of surgical guide support and implant site location on the accuracy of static Computer-Assisted Implant Surgery (sCAIS) in partially edentulous patients. Materials and methods: 375 replica implants were inserted in 85 study models. Surgical implant placement was done using static 3D printed surgical guides, which were designed to be supported either by all the teeth present in the model (full arch), or by 4-teeth), 3-teeth or 2-teeth. Each study model included three single-tooth gap (STG) situations; one extraction socket site and two implants placed in a distal extension situation. Preplanned and postoperative implant positions were compared using the treatment-evaluation tool in digital software. 3-dimensional and angular deviations were measured. Statistical analysis was done using ANOVA, and pairwise t tests and Bonferroni-Holm's adjustment were applied as a post hoc test. Results: Accuracy of surgical guides used in sCAIS was significantly affected by the number and type of teeth used for its support. Guides supported by 4 teeth were not significantly different from accuracy of full-arch-supported guides (p > .05). Guide support by posterior teeth was associated with an increased level of accuracy, when compared to anterior teeth guide support. Implants placed in extraction sockets were associated with significantly higher 3D and angular deviation values (p < .05), and surgical guides with a distal extension situation resulted in significantly higher deviation values (p < .05). Conclusion: The number and location of teeth supporting the surgical guide can significantly influence the accuracy of sCAIS, with 4 teeth providing equal accuracy to full-arch guides in (STG) situations.
MeSH term(s)	Computer-Aided Design ; Dental Implantation, Endosseous ; Humans ; Imaging, Three-Dimensional ; Mouth, Edentulous ; Printing, Three-Dimensional ; Surgery, Computer-Assisted
Language	English
Publishing date	2019-08-20
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	1067626-0
ISSN	1600-0501 ; 0905-7161
ISSN (online)	1600-0501
ISSN	0905-7161
DOI	10.1111/clr.13520
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Article ; Online: Mandibular implant-supported fixed complete dental prostheses on implants with ultrashort and standard length: A pilot treatment.

Schimmel, Martin / Janner, Simone F M / Joda, Tim / Wittneben, Julia G / McKenna, Gerald / Brägger, Urs

The Journal of prosthetic dentistry

2020 Volume 126, Issue 2, Page(s) 137–143

Abstract: Edentulous patients may be restored with complete-arch implant-supported fixed complete dental prostheses (IFCDPs) on angled distal implants or on parallel implants distributed equally across the mandible to increase the area of support. A treatment is ... ...

Abstract	Edentulous patients may be restored with complete-arch implant-supported fixed complete dental prostheses (IFCDPs) on angled distal implants or on parallel implants distributed equally across the mandible to increase the area of support. A treatment is presented to introduce the clinical concept of providing edentulous patients with an implant-supported fixed complete dental prosthesison parallel tissue-level implants in the mandible with standard length implants interforaminally and ultrashort implants distally. A structured prosthetic approach was used for the tooth arrangement with a modified workflow as per the Biofunctional Prosthetic System adapted for static computer-aided implant surgery (s-CAIS) and computer-aided design and computer-aided manufacturing (CAD-CAM) of the screw-retained implant-supported fixed complete dental prosthesis. The concept offered advantages in challenging anatomic, surgical, and prosthetic conditions; providing distal nonangled abutments and implant platforms, which were straightforward to clean. If necessary, the prosthesis could have been easily converted into a removable overdenture using the existing digital prosthetic arrangement. Should implant removal be required, the extrashort implants can be removed with minimal surgical risk or morbidity.
MeSH term(s)	Computer-Aided Design ; Dental Implants ; Dental Prosthesis Design ; Dental Prosthesis, Implant-Supported ; Denture, Overlay ; Follow-Up Studies ; Humans ; Jaw, Edentulous/surgery ; Mandible/surgery
Chemical Substances	Dental Implants
Language	English
Publishing date	2020-07-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	218157-5
ISSN	1097-6841 ; 0022-3913
ISSN (online)	1097-6841
ISSN	0022-3913
DOI	10.1016/j.prosdent.2020.04.013
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