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Book: Differential diagnoses in surgical pathology: Breast

Simpson, Jean F. / Sanders, Melinda E.

(Differential diagnoses in surgical pathology)

2017

Title variant	Breast
Author's details	Jean F. Simpson, Melinda E. Sanders
Series title	Differential diagnoses in surgical pathology
Keywords	Breast Neoplasms / diagnosis ; Breast Neoplasms / pathology ; Diagnosis, Differential ; Pathology, Surgical / methods
Language	English
Size	ix, 270 Seiten, Illustrationen
Publisher	Wolters Kluwer
Publishing place	Philadelphia
Publishing country	United States
Document type	Book
Note	Includes bibliographical references and index ; Zugang zur Online-Ausgabe über Code
HBZ-ID	HT019640041
ISBN	978-1-4963-0065-2 ; 9781496375391 ; 1-4963-0065-3 ; 1496375394
Database	Catalogue ZB MED Medicine, Health

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2018 A 485

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Book: Breast specimen radiography

Rubin, Eva / Simpson, Jean F.

needle localization and radiographic pathologic correlation

1998

Author's details	Eva Rubin ; Jean F. Simpson
Language	English
Size	XII, 206 S. : zahlr. Ill.
Publisher	Lippincott-Raven
Publishing place	Philadelphia u.a.
Publishing country	United States
Document type	Book
HBZ-ID	HT008745367
ISBN	0-3975-1667-3 ; 978-0-3975-1667-4
Database	Catalogue ZB MED Medicine, Health

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1998 A 4821

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Article: Update on atypical epithelial hyperplasia and ductal carcinoma in situ.

Simpson, Jean F

Pathology

2008 Volume 41, Issue 1, Page(s) 36–39

Abstract: Atypical ductal hyperplasia (ADH) as an indicator of increased risk for developing breast cancer is well established. Refinement in its molecular characterisation, especially as it relates to risk, continues to be challenging, largely because of its ... ...

Abstract	Atypical ductal hyperplasia (ADH) as an indicator of increased risk for developing breast cancer is well established. Refinement in its molecular characterisation, especially as it relates to risk, continues to be challenging, largely because of its small and very focal nature. Also a challenge is appropriate management of ADH when present on core biopsy. Additional support for ductal carcinoma in situ (DCIS) as a precursor to invasive cancer, as well as recent molecular characterisation of DCIS are presented. The importance of margin assessment in cases of DCIS and the limited role for sentinel lymph node biopsy in this setting are reviewed.
MeSH term(s)	Biopsy, Needle ; Breast Neoplasms/diagnosis ; Breast Neoplasms/epidemiology ; Breast Neoplasms/pathology ; Carcinoma, Intraductal, Noninfiltrating/diagnosis ; Carcinoma, Intraductal, Noninfiltrating/pathology ; Diagnosis, Differential ; Female ; Humans ; Hyperplasia/diagnosis ; Hyperplasia/pathology ; Risk Factors ; Sentinel Lymph Node Biopsy
Language	English
Publishing date	2008-11-19
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	7085-3
ISSN	1465-3931 ; 0031-3025
ISSN (online)	1465-3931
ISSN	0031-3025
DOI	10.1080/00313020802568097
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 723: Show issues

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Book: Breast

Simpson, Jean F / Sanders, Melinda E

(Differential diagnoses in surgical pathology)

2017

Author's details	Jean F. Simpson, Melinda E. Sanders
Series title	Differential diagnoses in surgical pathology
MeSH term(s)	Breast Neoplasms/diagnosis ; Breast Neoplasms/pathology ; Diagnosis, Differential ; Pathology, Surgical/methods
Language	English
Size	ix, 270 pages :, illustrations
Document type	Book
ISBN	9781496300652 ; 1496300653
Database	Catalogue of the US National Library of Medicine (NLM)

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Article ; Online: Using hospital discharge data for injury research or surveillance? An observational study illustrating the impact of administrative change.

Davie, Gabrielle / Barson, Dave / Simpson, Jean C / Lilley, Rebbecca / Gulliver, Pauline / Cryer, Colin

Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention

2019 Volume 25, Issue 6, Page(s) 540–545

Abstract: Introduction: Hospital discharge data provide an important basis for determining priorities for injury prevention and monitoring trends in incidence. This study aims to illustrate the impact of a recent change in administrative practice on estimates of ... ...

Abstract	Introduction: Hospital discharge data provide an important basis for determining priorities for injury prevention and monitoring trends in incidence. This study aims to illustrate the impact of a recent change in administrative practice on estimates of hospitalised injury incidence and to investigate the extent to which different case selection affects trends in injury incidence rates. Methods: New Zealand (NZ) hospital discharges (2000-2014) with a primary diagnosis of injury were identified. Additional case selection criteria included first admissions only, and for serious injury, a high threat-to-life estimate. Comparisons were made, over time and by District Health Board, between hospitalised injury incidence estimates that included, or not, short-stay emergency department (SSED) discharges. Results: Of the 1 229 772 injury hospital discharges, 365 114 were SSED; 16% of the annual total in 2000, 38% in 2014. Identification of readmissions prior to the exclusion of SSED discharges resulted in 30 724 cases being erroneously removed. Age-standardised rates of hospitalised injury over the 15-year period increased by, on average, 2.7% per year when SSED discharges were included; there was minimal secular change (-0.2%) when SSEDs were excluded. For serious hospitalised injury, the annual increase was 2.3% when SSED was included compared with 1.1% when SSEDs were excluded. Conclusion: Spurious trends in hospitalised injury incidence can result when administrative practices are not appropriately accounted for. Exclusion of SSED discharges before the identification of readmissions and the use of a severity threshold are recommended to minimise the reporting bias in NZ hospitalised injury incidence estimates.
MeSH term(s)	Data Collection/statistics & numerical data ; Emergency Service, Hospital/statistics & numerical data ; Health Services Research ; Hospital Records/standards ; Hospitalization/statistics & numerical data ; Humans ; Incidence ; New Zealand/epidemiology ; Patient Discharge/statistics & numerical data ; Wounds and Injuries/epidemiology
Language	English
Publishing date	2019-05-09
Publishing country	England
Document type	Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
ZDB-ID	1433667-4
ISSN	1475-5785 ; 1353-8047
ISSN (online)	1475-5785
ISSN	1353-8047
DOI	10.1136/injuryprev-2019-043201
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 4910: Show issues

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Article ; Online: Artifactual Displacement of Ductal Carcinoma In Situ (ADDCIS) (Toothpaste Effect): A Mimicker of Invasive Ductal Carcinoma.

Shabihkhani, Maryam / Simpson, Jean F / White, Marissa J / Cimino-Mathews, Ashley / Argani, Pedram

The American journal of surgical pathology

2019 Volume 44, Issue 1, Page(s) 120–128

Abstract: Needle tract displacement is a recognized mimicker of invasive ductal carcinoma (IDC). Artifactual displacement of ductal carcinoma in situ (ADDCIS) unassociated with needle tracts may occur secondary to mechanical compression of breast specimens but has ...

Abstract	Needle tract displacement is a recognized mimicker of invasive ductal carcinoma (IDC). Artifactual displacement of ductal carcinoma in situ (ADDCIS) unassociated with needle tracts may occur secondary to mechanical compression of breast specimens but has not been systematically studied. We identified 16 cases of ADDCIS unassociated with needle tract changes; the majority (75%) were internal referrals to the breast pathology service to rule out IDC, 19% were received as external diagnostic consultations to rule out IDC, and 6% were routine second review cases originally diagnosed as IDC at an outside hospital. The majority (62.5%) of ADDCIS occurred in lumpectomies, whereas 25% occurred in mastectomies and 12.5% in core biopsies. ADDCIS foci ranged from <1 to 5 mm; however, all ADDCIS spanning >4 mm demonstrated a linear pattern of displacement. In all cases, ADDCIS involved mammary stroma in a nonlobular distribution; in half, ADDCIS extended between benign lobules. Immunohistochemistry revealed no myoepithelial cells around the ADDCIS (n=7), adding to the concern for IDC. However, in contrast to most IDC, ADDCIS lacked stromal reaction and showed degenerative, smudged chromatin. None of the 9 patients with significant follow-up (mean, 7 y) developed metastasis. All received further local therapy for DCIS (5 radiation, 4 completion mastectomy); 1 received adjuvant systemic therapy (hormone therapy for contralateral IDC). In conclusion, ADDCIS mimics IDC, particularly given its permeative pattern and absence of myoepithelial cells. ADDCIS is most common in lumpectomies but can occur in mastectomies or core biopsies. Diagnostic clues include smudged nuclear chromatin, lack of stromal response, and linear pattern of displacement in larger lesions. The benign follow-up without systemic therapy supports our view that ADDCIS does not represent true IDC.
MeSH term(s)	Adult ; Aged ; Artifacts ; Breast Neoplasms/pathology ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Intraductal, Noninfiltrating/pathology ; Diagnosis, Differential ; Female ; Humans ; Middle Aged ; Neoplasm Invasiveness ; Prospective Studies
Language	English
Publishing date	2019-09-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	752964-8
ISSN	1532-0979 ; 0147-5185
ISSN (online)	1532-0979
ISSN	0147-5185
DOI	10.1097/PAS.0000000000001370
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1356: Show issues

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Article ; Online: The pathologist as a teacher.

Simpson, Jean F / Washington, Kay

American journal of clinical pathology

2012 Volume 138, Issue 3, Page(s) 320

MeSH term(s)	Education, Medical, Graduate ; Fellowships and Scholarships ; Humans ; Internship and Residency ; Pathology/education
Language	English
Publishing date	2012-09
Publishing country	England
Document type	Editorial
ZDB-ID	2944-0
ISSN	1943-7722 ; 0002-9173
ISSN (online)	1943-7722
ISSN	0002-9173
DOI	10.1309/AJCPDUMLZI2LT1SB
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Ud II Zs.91: Show issues

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Article ; Online: Preventing unintentional childhood injury at home: injury circumstances and interventions.

Simpson, Jean C / Nicholls, Jane

International journal of injury control and safety promotion

2012 Volume 19, Issue 2, Page(s) 141–151

Abstract: New Zealand's (NZ) preschoolers carry the greatest injury burden among children aged 0-14 years. These injuries commonly occur at home. To identify how NZ addresses child injury the 1990s national injury datasets and associated free text were examined ... ...

Abstract	New Zealand's (NZ) preschoolers carry the greatest injury burden among children aged 0-14 years. These injuries commonly occur at home. To identify how NZ addresses child injury the 1990s national injury datasets and associated free text were examined retrospectively, NZ injury circumstances and interventions were compared to internationally recognised hazards and best practice, and whether NZ interventions addressed common circumstances of injury was assessed. Certain injuries, often associated with activities of daily living, were not addressed by interventions, although most interventions advocated internationally are implemented in NZ. Possible reasons for main injuries not being addressed were the specificity and variable effectiveness of interventions, normality of many injury circumstances, difficulties in evaluating complex environments, and the need for active intervention. There is considerable scope for NZ to improve its child safety. It is unlikely that simple solutions will be found for complex circumstances in which injury events occur. Strategies to address multifaceted problems requiring changes to personal, social and societal factors are required, with evaluation methods able to match their complexity.
MeSH term(s)	Accidental Falls/prevention & control ; Accidents, Home/prevention & control ; Asphyxia/epidemiology ; Asphyxia/prevention & control ; Burns/epidemiology ; Burns/prevention & control ; Child, Preschool ; Drowning/epidemiology ; Drowning/prevention & control ; Health Promotion ; Humans ; New Zealand/epidemiology ; Poisoning/epidemiology ; Poisoning/prevention & control ; Public Policy ; Retrospective Studies ; Safety/legislation & jurisprudence ; Safety/standards ; Wounds and Injuries/epidemiology ; Wounds and Injuries/prevention & control
Language	English
Publishing date	2012
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2011468-0
ISSN	1745-7319 ; 0929-8347 ; 1387-3059 ; 1566-0974 ; 1745-7300
ISSN (online)	1745-7319
ISSN	0929-8347 ; 1387-3059 ; 1566-0974 ; 1745-7300
DOI	10.1080/17457300.2011.635208
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Motorcyclists' perceptions and experiences of riding and risk and their advice for safety.

Simpson, Jean C / Wilson, Suzanne / Currey, Nandika

Traffic injury prevention

2015 Volume 16, Issue 2, Page(s) 159–167

Abstract: Objective: To examine the knowledge, observations, and perceptions of motorcycle riders on the risks of on-road motorcycling and potential safety measures to give insight and guidance in developing policies, programs, and legislation to improve the ... ...

Abstract	Objective: To examine the knowledge, observations, and perceptions of motorcycle riders on the risks of on-road motorcycling and potential safety measures to give insight and guidance in developing policies, programs, and legislation to improve the safety of motorcyclists. Methods: Individual and focus group interviews were conducted with dealers and a cross section of motorcyclists from selected regions across New Zealand. The interviews were analyzed and coded to identify common themes and diverse perspectives on why people rode motorcycles, riders' perceptions on risk, and possible safety strategies for on-road motorcycling. Findings and discussion: Motorcycling has major benefits for riders, although most riders perceived that the risks could be severe and they were susceptible to injury. Their observations on the threats and barriers to safety focused on 3 components: the rider, the motorcycle, and the environment. Risks included inexperience, not riding to the conditions, choice of motorcycle, protective clothing and conspicuity, and speed. The underlying risk of being on 2 wheels was accentuated by the availability of high-power motorcycles. The threats perceived in the environment included the behavior of other road users, especially car drivers, and the poor road conditions and surrounds encountered. Conclusions: Riders identified risks that have been recognized in the road safety literature as well as risks for which there are no engineering or scientific solutions. To effectively increase motorcyclist safety, recognition of the commonalities and the differences between motorcyclists' perspectives and proposed strategies is needed. This approach is more likely to engage riders and thus support positive behavior change among riders and drivers.
MeSH term(s)	Accidents, Traffic/prevention & control ; Focus Groups ; Humans ; Motorcycles ; New Zealand ; Qualitative Research ; Risk Assessment ; Risk-Taking ; Safety ; Wounds and Injuries/prevention & control
Language	English
Publishing date	2015
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2089818-6
ISSN	1538-957X ; 1538-9588
ISSN (online)	1538-957X
ISSN	1538-9588
DOI	10.1080/15389588.2014.911852
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Can we know what to do when DCIS is diagnosed?

Sanders, Melinda E / Simpson, Jean F

Oncology (Williston Park, N.Y.)

2011 Volume 25, Issue 9, Page(s) 852–856

Abstract: Utilizing routine histopathologic parameters obtained from appropriately handled lumpectomy and mastectomy specimens, a rational therapeutic plan based on epidemiologic and outcome-based data can be devised for any patient diagnosed with ductal carcinoma ...

Abstract	Utilizing routine histopathologic parameters obtained from appropriately handled lumpectomy and mastectomy specimens, a rational therapeutic plan based on epidemiologic and outcome-based data can be devised for any patient diagnosed with ductal carcinoma in situ (DCIS). In order to make a sound decision when weighing the current treatment options for DCIS--which include excision alone, excision plus radiation, and mastectomy--the following are mandatory: 1) assurance of an accurate diagnosis, 2) assessment of DCIS size and grade, and 3) careful margin evaluation. Accurate grading of DCIS is critical, since high nuclear grade and the presence of necrosis are highly predictive of the inability to achieve adequate margins, of local recurrence, and of the probability of missed areas of invasion. Margin status is the single most important determinant of local control following breast conservation for DCIS; numerous studies have shown that as the margin width increases, the risk of local failure decreases. The pros and cons of irradiating conservatively treated patients with DCIS should be carefully weighed on a case-by-case basis. Despite the 20-year-old dogma that all patients treated with breast conservation should receive postoperative radiation, a subset of patients who can be successfully treated by excision alone has been identified.
MeSH term(s)	Biomarkers, Tumor/analysis ; Breast Neoplasms/diagnosis ; Breast Neoplasms/pathology ; Breast Neoplasms/therapy ; Carcinoma, Intraductal, Noninfiltrating/diagnosis ; Carcinoma, Intraductal, Noninfiltrating/pathology ; Carcinoma, Intraductal, Noninfiltrating/therapy ; Combined Modality Therapy ; Diagnosis, Differential ; Female ; Humans ; Sentinel Lymph Node Biopsy
Chemical Substances	Biomarkers, Tumor
Language	English
Publishing date	2011-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	1067950-9
ISSN	0890-9091
ISSN	0890-9091
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Zs.A 3168: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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