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  1. Book ; Audio / Video ; Thesis: Studien zur Gen-Expression und zum DNA-Bindungsverhalten der humanen Krab-Zinkfingerproteine Kox1 und Kox19

    Sina, Christian

    2004  

    Author's details vorgelegt von Christian Sina
    Language German
    Size 1 CD-ROM, 12 cm
    Publishing country Germany
    Document type Book ; Audio / Video ; Thesis
    Thesis / German Habilitation thesis Rostock, Univ., Diss., 2004
    HBZ-ID HT014022110
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2004 MO 165 order for loan Magazin

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  2. Article: Liebe Leserinnen und Leser,

    Sina, Christian

    Aktuelle Ernährungsmedizin

    2023  Volume 48, Issue 06, Page(s) 386–386

    Abstract: ich freue mich außerordentlich, in Vertretung unseres geschätzten Herausgebers, Prof. Stephan Bischoff, dieses Editorial verfassen zu dürfen. ...

    Abstract ich freue mich außerordentlich, in Vertretung unseres geschätzten Herausgebers, Prof. Stephan Bischoff, dieses Editorial verfassen zu dürfen.
    Language German
    Publishing date 2023-12-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2063356-7
    ISSN 1438-9916 ; 0341-0501
    ISSN (online) 1438-9916
    ISSN 0341-0501
    DOI 10.1055/a-2135-1741
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  3. Article ; Online: Personalized nutrition as the catalyst for building food-resilient cities.

    Ziolkovska, Anna / Sina, Christian

    Nature food

    2024  Volume 5, Issue 4, Page(s) 267–269

    MeSH term(s) Humans ; Cities ; Nutritional Status ; Food Supply ; Precision Medicine/methods
    Language English
    Publishing date 2024-04-01
    Publishing country England
    Document type Journal Article
    ISSN 2662-1355
    ISSN (online) 2662-1355
    DOI 10.1038/s43016-024-00959-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Sehr geehrte Leserinnen und Leser,

    Sina, Christian

    Aktuelle Ernährungsmedizin

    2022  Volume 47, Issue 05, Page(s) 343–343

    Abstract: mangelernährte Menschen haben das Recht auf wirksame Versorgung – Die Deutsche Gesellschaft für Ernährungsmedizin unterzeichnet Vienna Declaration zu krankheitsassoziierter Mangelernährung! ...

    Abstract mangelernährte Menschen haben das Recht auf wirksame Versorgung – Die Deutsche Gesellschaft für Ernährungsmedizin unterzeichnet Vienna Declaration zu krankheitsassoziierter Mangelernährung!
    Language German
    Publishing date 2022-10-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2063356-7
    ISSN 1438-9916 ; 0341-0501
    ISSN (online) 1438-9916
    ISSN 0341-0501
    DOI 10.1055/a-1859-2199
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  5. Article: Impacts of the SARS-CoV-2 pandemic on the dietary practices of university students in Germany.

    Dreyer, Jana O / Brandt, Alexander C / Lichtenstein, Silke / Sina, Christian / Smollich, Martin

    Frontiers in nutrition

    2024  Volume 11, Page(s) 1302308

    Abstract: Purpose: The dietary practices (DPs) of university students are influenced by many external factors. Therefore, we investigate how the DPs of students in Germany changed during the SARS-CoV-2 pandemic, what the main motivations were for those changes, ... ...

    Abstract Purpose: The dietary practices (DPs) of university students are influenced by many external factors. Therefore, we investigate how the DPs of students in Germany changed during the SARS-CoV-2 pandemic, what the main motivations were for those changes, and what effect the closure of university catering had on the DPs of students.
    Methods: A total of 560 students from two universities in Lübeck (Germany) were surveyed online during a pilot phase. The final online questionnaire was subsequently administered at 10 other German universities (399 respondents). The questionnaire surveyed sociodemographic factors, dietary habits, food consumption frequencies, and the relevance of university catering before and during the SARS-CoV-2 pandemic.
    Results: Regarding changes in DPs, similarities to previous studies were found, especially positive eating behaviors and an increasing interest in health- and nutrition-related sustainability. Students prepared meals freshly more often during the pandemic; consumed legumes, plant-based meats and dairy alternatives more often; and reduced their consumption of meat and milk compared to before the pandemic. The consumption frequency of sweets also decreased. It was observed that students consider eating communal in the university canteen to be highly relevant for their social interactions, which was only possible to a limited extent during the pandemic.
    Conclusion: In Germany, the DPs of university students as well as criteria regarding health and sustainability changed during the first 2 years of the SARS-CoV-2 pandemic. The social aspect of DPs became evident due to closed university catering. Still, changes in dietary patterns and eating habits were positively related to health and revealed some differences in the cross section of the population.
    Language English
    Publishing date 2024-03-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2024.1302308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online ; Thesis: Host genome – microbiome interaction and its influence on chronic inflammation in the skin in the mouse

    Hartmann, Adina-Malin [Verfasser] / Ibrahim, Saleh [Akademischer Betreuer] / Sina, Christian [Akademischer Betreuer]

    2024  

    Author's details Adina-Malin Hartmann ; Akademische Betreuer: Saleh Ibrahim, Christian Sina
    Keywords Naturwissenschaften ; Science
    Subject code sg500
    Language English
    Publisher Zentrale Hochschulbibliothek Lübeck
    Publishing place Lübeck
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  7. Article ; Online: Inadequate Choline Intake in Pregnant Women in Germany.

    Roeren, Merle / Kordowski, Anna / Sina, Christian / Smollich, Martin

    Nutrients

    2022  Volume 14, Issue 22

    Abstract: Choline is an essential nutrient that is involved in various developmental processes during pregnancy. While the general adequate choline intake (AI) for adults has been set at 400 mg/day by the European Food Safety Authority (EFSA), an AI of 480 mg/day ... ...

    Abstract Choline is an essential nutrient that is involved in various developmental processes during pregnancy. While the general adequate choline intake (AI) for adults has been set at 400 mg/day by the European Food Safety Authority (EFSA), an AI of 480 mg/day has been derived for pregnant women. To date, the choline intake of pregnant women in Germany has not been investigated yet. Therefore, in this survey, the total choline intake from dietary and supplementary sources in pregnant women was estimated using an online questionnaire. A total of 516 pregnant women participated in the survey, of which 283 met the inclusion criteria (13 to 41 weeks of gestational age, 19−45 years). 224 (79%) of the participants followed an omnivorous diet, 59 (21%) were vegetarian or vegan. Median choline intake was 260.4 (±141.4) mg/day, and only 19 women (7%) achieved the adequate choline intake. The median choline intake of omnivores was significantly higher than that of vegetarians/vegans (269.5 ± 141.5 mg/day vs. 205.2 ± 101.2 mg/day; p < 0.0001). 5% (13/283) of pregnant women took choline-containing dietary supplements. In these women, dietary supplements provided 19% of the total choline intake. Due to the importance of choline for the developmental processes during pregnancy, the study results prove the urgent need for an improved choline supply for pregnant women.
    MeSH term(s) Pregnancy ; Adult ; Female ; Humans ; Young Adult ; Middle Aged ; Choline ; Pregnant Women ; Germany ; Vegans ; Vegetarians
    Chemical Substances Choline (N91BDP6H0X)
    Language English
    Publishing date 2022-11-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14224862
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Gut Microbiome Analysis for Personalized Nutrition: The State of Science

    Simon, Marie‐Christine / Sina, Christian / Ferrario, Paola G. / Daniel, Hannelore

    Molecular Nutrition & Food Research. 2023 Jan., v. 67, no. 1 p.e2200476-

    2023  

    Abstract: Whereas most concepts of personalized nutrition (PN) in the past, included genotyping, recent years have brought new approaches that include microbiome analysis to optimize recommendations for diet and lifestyle changes. The new approach, offered by ... ...

    Institution Working Group “Personalized Nutrition” of the German Nutrition SocietyDepartment of Nutrition and Food Science, Nutrition and Microbiome, University of Bonn, 53115, Bonn, Germany
    Abstract Whereas most concepts of personalized nutrition (PN) in the past, included genotyping, recent years have brought new approaches that include microbiome analysis to optimize recommendations for diet and lifestyle changes. The new approach, offered by companies, that microbiome analysis provides a real benefit to either more concise recommendations or for increased compliance to PN, is largely lacking scientific validation. Although the microbiome field shows enormous proliferation, it has some major flaws that make its use in the public health domain currently critical. Starting with the quality and representative character of the stool samples, its processing and analysis as well as assembly of metagenome data and the interpretation. Moreover, there is still no consensus of what constitutes a “normal/healthy” microbiome, nor what features characterize a dysbiotic microbiome. And, based on hundreds of individual parameters and environmental factors, the intestinal microbiome shows a huge variability and consequently changing one factor—such as food intake—is likely to have a limited impact in achieving optimized health. The present review intends to summarize the state of consolidated knowledge on human gut microbiome in the context of diet and disease, its key features, and its influencing factors as well as its “add‐on” quality for PN offers.
    Keywords compliance ; diet ; food research ; genotyping ; humans ; intestinal microorganisms ; lifestyle ; metagenomics ; microbiome ; public health
    Language English
    Dates of publication 2023-01
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note REVIEW
    ZDB-ID 2160372-8
    ISSN 1613-4133 ; 1613-4125
    ISSN (online) 1613-4133
    ISSN 1613-4125
    DOI 10.1002/mnfr.202200476
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Influence of nutrients and metabolites on the differentiation of plasma cells and implications for autoimmunity.

    Föh, Bandik / Buhre, Jana Sophia / Sina, Christian / Ehlers, Marc

    Frontiers in immunology

    2022  Volume 13, Page(s) 1004644

    Abstract: The modulation of inflammatory (auto)immune reactions by nutrients and gut bacterial metabolites is of great interest for potential preventive and therapeutic strategies. B cell-derived plasma cells are major players in inflammatory (auto)immune ... ...

    Abstract The modulation of inflammatory (auto)immune reactions by nutrients and gut bacterial metabolites is of great interest for potential preventive and therapeutic strategies. B cell-derived plasma cells are major players in inflammatory (auto)immune responses and can exhibit pro- or anti-inflammatory effects through (auto)antibody-dependent and -independent functions. Emerging evidence indicates a key role of nutrients and microbial metabolites in regulating the differentiation of plasma cells as well as their differentiation to pro- or anti-inflammatory phenotypes. These effects might be mediated indirectly by influencing other immune cells or directly through B cell-intrinsic mechanisms. Here, we provide an overview of nutrients and metabolites that influence B cell-intrinsic signaling pathways regulating B cell activation, plasma cell differentiation, and effector functions. Furthermore, we outline important inflammatory plasma cell phenotypes whose differentiation could be targeted by nutrients and microbial metabolites. Finally, we discuss possible implications for inflammatory (auto)immune conditions.
    MeSH term(s) Plasma Cells ; Autoimmunity ; Cell Differentiation ; B-Lymphocytes ; Nutrients
    Language English
    Publishing date 2022-11-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.1004644
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Gut Microbiome Analysis for Personalized Nutrition: The State of Science.

    Simon, Marie-Christine / Sina, Christian / Ferrario, Paola G / Daniel, Hannelore

    Molecular nutrition & food research

    2022  Volume 67, Issue 1, Page(s) e2200476

    Abstract: Whereas most concepts of personalized nutrition (PN) in the past, included genotyping, recent years have brought new approaches that include microbiome analysis to optimize recommendations for diet and lifestyle changes. The new approach, offered by ... ...

    Abstract Whereas most concepts of personalized nutrition (PN) in the past, included genotyping, recent years have brought new approaches that include microbiome analysis to optimize recommendations for diet and lifestyle changes. The new approach, offered by companies, that microbiome analysis provides a real benefit to either more concise recommendations or for increased compliance to PN, is largely lacking scientific validation. Although the microbiome field shows enormous proliferation, it has some major flaws that make its use in the public health domain currently critical. Starting with the quality and representative character of the stool samples, its processing and analysis as well as assembly of metagenome data and the interpretation. Moreover, there is still no consensus of what constitutes a "normal/healthy" microbiome, nor what features characterize a dysbiotic microbiome. And, based on hundreds of individual parameters and environmental factors, the intestinal microbiome shows a huge variability and consequently changing one factor-such as food intake-is likely to have a limited impact in achieving optimized health. The present review intends to summarize the state of consolidated knowledge on human gut microbiome in the context of diet and disease, its key features, and its influencing factors as well as its "add-on" quality for PN offers.
    MeSH term(s) Humans ; Gastrointestinal Microbiome ; Nutritional Status ; Diet ; Microbiota ; Metagenome
    Language English
    Publishing date 2022-11-24
    Publishing country Germany
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2160372-8
    ISSN 1613-4133 ; 1613-4125
    ISSN (online) 1613-4133
    ISSN 1613-4125
    DOI 10.1002/mnfr.202200476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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