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  1. Article: Ignoring Pantone matching system: A recipe for disaster.

    Singh, Ajmer

    Journal of anaesthesiology, clinical pharmacology

    2023  Volume 39, Issue 4, Page(s) 652–653

    Language English
    Publishing date 2023-12-20
    Publishing country India
    Document type Journal Article
    ZDB-ID 1401760-x
    ISSN 0970-9185
    ISSN 0970-9185
    DOI 10.4103/joacp.joacp_8_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4830: Show issues Location:
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  2. Article ; Online: Supramitral membrane with left atrial appendage thrombus: A rare entity.

    Singh, Ajmer

    Annals of cardiac anaesthesia

    2022  Volume 25, Issue 3, Page(s) 366–367

    Abstract: A 4-year-old child with supramitral membrane (SMM) causing severe mitral stenosis (MS) was taken for excision of the membrane. Intraoperative transesophageal echocardiography showed a large thrombus in the left atrial appendage (LAA) in addition to SMM. ... ...

    Abstract A 4-year-old child with supramitral membrane (SMM) causing severe mitral stenosis (MS) was taken for excision of the membrane. Intraoperative transesophageal echocardiography showed a large thrombus in the left atrial appendage (LAA) in addition to SMM. The case underscores the importance of this extremely rare association and prompt therapy to prevent catastrophic consequences.
    MeSH term(s) Atrial Appendage/diagnostic imaging ; Atrial Appendage/surgery ; Atrial Fibrillation/complications ; Child, Preschool ; Echocardiography ; Echocardiography, Transesophageal ; Humans ; Mitral Valve Stenosis/complications ; Mitral Valve Stenosis/diagnostic imaging ; Mitral Valve Stenosis/surgery ; Thrombosis/complications ; Thrombosis/diagnostic imaging ; Thrombosis/surgery
    Language English
    Publishing date 2022-07-07
    Publishing country India
    Document type Case Reports
    ZDB-ID 2106866-5
    ISSN 0974-5181 ; 0971-9784
    ISSN (online) 0974-5181
    ISSN 0971-9784
    DOI 10.4103/aca.aca_32_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: What Device is Seen in the Chest X-Ray?

    Singh, Ajmer / Mukati, Ravina

    Annals of cardiac anaesthesia

    2024  Volume 27, Issue 2, Page(s) 180–181

    MeSH term(s) Humans ; X-Rays ; Radiography
    Language English
    Publishing date 2024-04-12
    Publishing country India
    Document type Journal Article
    ZDB-ID 2106866-5
    ISSN 0974-5181 ; 0971-9784
    ISSN (online) 0974-5181
    ISSN 0971-9784
    DOI 10.4103/aca.aca_207_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Absent right superior vena cava and persistent left superior vena cava: An incidental finding.

    Joshi, Swati / Singh, Ajmer

    Annals of cardiac anaesthesia

    2023  Volume 26, Issue 4, Page(s) 433–434

    Abstract: A patient with Marfan syndrome undergoing Bentall operation was found to have an absent right superior vena cava and persistent left superior vena cava. The dilation of coronary sinus raised the suspicion of persistent left superior vena cava. The ... ...

    Abstract A patient with Marfan syndrome undergoing Bentall operation was found to have an absent right superior vena cava and persistent left superior vena cava. The dilation of coronary sinus raised the suspicion of persistent left superior vena cava. The diagnosis was confirmed by agitated saline contrast echocardiography and computed tomography of the chest.
    MeSH term(s) Humans ; Persistent Left Superior Vena Cava ; Vena Cava, Superior/diagnostic imaging ; Vena Cava, Superior/surgery ; Incidental Findings ; Echocardiography ; Coronary Sinus/diagnostic imaging
    Language English
    Publishing date 2023-11-10
    Publishing country India
    Document type Journal Article
    ZDB-ID 2106866-5
    ISSN 0974-5181 ; 0971-9784
    ISSN (online) 0974-5181
    ISSN 0971-9784
    DOI 10.4103/aca.aca_91_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A feature engineering-based machine learning technique to detect and classify lung and colon cancer from histopathological images.

    Chhillar, Indu / Singh, Ajmer

    Medical & biological engineering & computing

    2023  Volume 62, Issue 3, Page(s) 913–924

    Abstract: Globally, lung and colon cancers are among the most prevalent and lethal tumors. Early cancer identification is essential to increase the likelihood of survival. Histopathological images are considered an appropriate tool for diagnosing cancer, which is ... ...

    Abstract Globally, lung and colon cancers are among the most prevalent and lethal tumors. Early cancer identification is essential to increase the likelihood of survival. Histopathological images are considered an appropriate tool for diagnosing cancer, which is tedious and error-prone if done manually. Recently, machine learning methods based on feature engineering have gained prominence in automatic histopathological image classification. Furthermore, these methods are more interpretable than deep learning, which operates in a "black box" manner. In the medical profession, the interpretability of a technique is critical to gaining the trust of end users to adopt it. In view of the above, this work aims to create an accurate and interpretable machine-learning technique for the automated classification of lung and colon cancers from histopathology images. In the proposed approach, following the preprocessing steps, texture and color features are retrieved by utilizing the Haralick and Color histogram feature extraction algorithms, respectively. The obtained features are concatenated to form a single feature set. The three feature sets (texture, color, and combined features) are passed into the Light Gradient Boosting Machine (LightGBM) classifier for classification. And their performance is evaluated on the LC25000 dataset using hold-out and stratified 10-fold cross-validation (Stratified 10-FCV) techniques. With a test/hold-out set, the LightGBM with texture, color, and combined features classifies the lung and colon cancer images with 97.72%, 99.92%, and 100% accuracy respectively. In addition, a stratified 10-fold cross-validation method also revealed that LightGBM's combined or color features performed well, with an excellent mean auc_mu score and a low mean multi_logloss value. Thus, this proposed technique can help histologists detect and classify lung and colon histopathology images more efficiently, effectively, and economically, resulting in more productivity.
    MeSH term(s) Humans ; Colonic Neoplasms/diagnostic imaging ; Machine Learning ; Algorithms ; Lung/diagnostic imaging
    Language English
    Publishing date 2023-12-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 282327-5
    ISSN 1741-0444 ; 0025-696X ; 0140-0118
    ISSN (online) 1741-0444
    ISSN 0025-696X ; 0140-0118
    DOI 10.1007/s11517-023-02984-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 294: Show issues Location:
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  6. Article ; Online: Remote Embolization of an Atrial Septal Occluder Device.

    Singh, Ajmer / Nanda, Chinmaya / Mehta, Yatin

    Journal of cardiothoracic and vascular anesthesia

    2024  Volume 38, Issue 4, Page(s) 1054–1055

    MeSH term(s) Humans ; Septal Occluder Device/adverse effects ; Echocardiography, Transesophageal ; Postoperative Complications ; Embolization, Therapeutic ; Heart Septal Defects, Atrial/diagnostic imaging ; Heart Septal Defects, Atrial/surgery ; Cardiac Catheterization ; Treatment Outcome
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Letter
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2024.01.002
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    Zs.MO 31: Show issues

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  7. Article ; Online: Impact of intraoperative haemoadsorption on outcomes of patients undergoing aortic surgery: a single-centre, prospective, observational study.

    Mehta, Yatin / Singh, Ajmer / Singh, Mandeep / Bhan, Anil / Trehan, Naresh

    Interdisciplinary cardiovascular and thoracic surgery

    2024  Volume 38, Issue 4

    Abstract: Objectives: To investigate the impact of a cytokine haemoadsorption (HA) device (CytoSorb®) on inflammatory markers and patients' outcome during aortic root surgery.: Methods: Prospective, observational study including all-comers with quasi- ... ...

    Abstract Objectives: To investigate the impact of a cytokine haemoadsorption (HA) device (CytoSorb®) on inflammatory markers and patients' outcome during aortic root surgery.
    Methods: Prospective, observational study including all-comers with quasi-randomization by strictly alternating inclusion (1:1 basis). Sixty patients undergoing elective aortic surgery were assigned to either HA group (n = 30) with intraoperative HA, or a control (C) group (n = 30). Primary outcomes were: (i) impact of HA on haemodynamic stability and need for vasopressors (vasoactive-inotropic score) and (ii) sequential organ failure assessment (SOFA) score. Secondary parameters included the impact of HA on the course of hyperinflammation using interleukin-6 and procalcitonin, duration of mechanical ventilation, and lengths of intensive care unit and hospital stay.
    Results: Noradrenaline requirement was significantly reduced in the HA group postoperatively compared to the C group (HA: 0.03 µg/kg/min vs C: 0.08 µg/kg/min, P = 0.004 at 2 h, and HA: 0.02 µg/kg/min vs C: 0.04 µg/kg/min, P = 0.004 at 24 h). This translated into a significantly lower vasoactive-inotropic score in the HA group. SOFA score was less in the HA group at all time points and reached statistical significance 2 h postoperatively (HA: 5.77 vs C: 7.43, P < 0.001). Intraoperative HA significantly reduced interleukin-6 levels (P < 0.05) at all time points, and procalcitonin at 2 h after discontinuation from cardiopulmonary bypass (P = 0.005). The duration of ventilation, intensive care unit and hospital stays were shorter in the HA group compared to the C group.
    Conclusions: Intraoperative HA has the potential to mitigate hyperinflammatory response leading to improved haemodynamics after aortic root surgery, thereby shortening the duration of ventilation, and lengths of intensive care unit and hospital stay. However, it must be evaluated in larger cohorts.
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Journal Article
    ISSN 2753-670X
    ISSN (online) 2753-670X
    DOI 10.1093/icvts/ivae050
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  8. Article ; Online: Successful Extracorporeal Cytokine Hemoadsorption in a Marfan Syndrome Patient with COVID-19 Undergoing Redo Bentall Procedure.

    Singh, Ajmer / Nanda, Chinmaya / Mehta, Yatin / Bhan, Anil

    The American journal of case reports

    2023  Volume 24, Page(s) e940383

    Abstract: BACKGROUND Patients with COVID-19 undergoing emergency or complex surgical procedures are at increased risk of developing perioperative complications. CytoSorb is a blood purification therapy used to remove circulating cytokines in conditions of ... ...

    Abstract BACKGROUND Patients with COVID-19 undergoing emergency or complex surgical procedures are at increased risk of developing perioperative complications. CytoSorb is a blood purification therapy used to remove circulating cytokines in conditions of hyperinflammation. This report is of a patient with COVID-19 requiring redo replacement of the aortic valve and aorta due to aortic aneurysm of the ascending aorta (Bentall procedure) associated with Marfan syndrome. The patient was successfully treated with extracorporeal cytokine hemoadsorption. CASE REPORT A 34-year-old man with Marfan syndrome, who had undergone a Bentall procedure in 2018, was admitted with symptoms of worsening dyspnea, tachycardia, fever, and confirmed COVID-19. Further diagnostic workup revealed dehiscence of the aortic root as well as moderate aortic regurgitation, in the context of a hyperinflammatory state. Anti-infective treatment was initiated. Given the severity of symptoms, COVID-19, echocardiography findings, and risk of aortic rupture, urgent Bentall surgery was performed. Additionally, a CytoSorb hemoadsorber was integrated into the cardiopulmonary bypass circuit to attenuate the anticipated systemic hyperinflammation. Intraoperatively, several blood products were administered due to excessive bleeding from the friable tissues and the pre-existing anemia and thrombocytopenia. Treatment was associated with marked improvements in vital parameters and inflammatory markers, and weaning from the ventilator and inotropes was possible after 48 hours. The remaining time in hospital was uneventful. CONCLUSIONS This report supports the findings from recent studies and reports that extracorporeal cytokine hemoadsorption has a role to play in reducing the systemic effects of cytokine storm associated with complex surgery involving cardiopulmonary bypass alongside severe infections, including COVID-19.
    MeSH term(s) Male ; Humans ; Adult ; Marfan Syndrome/complications ; COVID-19 ; Aortic Valve Insufficiency/etiology ; Aortic Valve Insufficiency/surgery ; Aorta ; Cytokines
    Chemical Substances Cytokines
    Language English
    Publishing date 2023-09-26
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.940383
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  9. Article ; Online: What flow is this!

    Singh, Ajmer / Nanda, Chinmaya / Mishra, Manisha / Mehta, Yatin

    Annals of cardiac anaesthesia

    2023  Volume 26, Issue 2, Page(s) 204–205

    Language English
    Publishing date 2023-09-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2106866-5
    ISSN 0974-5181 ; 0971-9784
    ISSN (online) 0974-5181
    ISSN 0971-9784
    DOI 10.4103/aca.aca_23_21
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  10. Article: Unexpected values of mixed venous blood analysis: Back to basics before sampling.

    Singh, Ajmer / Nanda, Chinmaya / Mehta, Yatin

    Journal of anaesthesiology, clinical pharmacology

    2023  Volume 39, Issue 3, Page(s) 509–510

    Language English
    Publishing date 2023-04-19
    Publishing country India
    Document type Journal Article
    ZDB-ID 1401760-x
    ISSN 0970-9185
    ISSN 0970-9185
    DOI 10.4103/joacp.joacp_537_21
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    In stock of ZB MED Cologne/Königswinter

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