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  1. Article ; Online: Correction: Understanding the bacterial community structure associated with the Eichhornia crassipes rootzone.

    Singh, Chandra Kant / Sodhi, Kushneet Kaur / Singh, Dileep Kumar

    Molecular biology reports

    2024  Volume 51, Issue 1, Page(s) 251

    Language English
    Publishing date 2024-02-01
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-024-09227-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1140: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Heavy Metals as Catalysts in the Evolution of Antimicrobial Resistance and the Mechanisms Underpinning Co-selection.

    Singh, Chandra Kant / Sodhi, Kushneet Kaur / Shree, Pallee / Nitin, V

    Current microbiology

    2024  Volume 81, Issue 6, Page(s) 148

    Abstract: The menace caused by antibiotic resistance in bacteria is acknowledged on a global scale. Concerns over the same are increasing because of the selection pressure exerted by a huge number of different antimicrobial agents, including heavy metals. Heavy ... ...

    Abstract The menace caused by antibiotic resistance in bacteria is acknowledged on a global scale. Concerns over the same are increasing because of the selection pressure exerted by a huge number of different antimicrobial agents, including heavy metals. Heavy metals are non-metabolizable and recalcitrant to degradation, therefore the bacteria can expel the pollutants out of the system and make it less harmful via different mechanisms. The selection of antibiotic-resistant bacteria may be influenced by heavy metals present in environmental reservoirs. Through co-resistance and cross-resistance processes, the presence of heavy metals in the environment can act as co-selecting agents, hence increasing resistance to both heavy metals and antibiotics. The horizontal gene transfer or mutation assists in the selection of mutant bacteria resistant to the polluted environment. Hence, bioremediation and biodegradation are sustainable methods for the natural clean-up of pollutants. This review sheds light on the occurrence of metal and antibiotic resistance in the environment via the co-resistance and cross-resistance mechanisms underpinning co-selection emphasizing the dearth of studies that specifically examine the method of co-selection in clinical settings. Furthermore, it is advised that future research incorporate both culture- and molecular-based methodologies to further our comprehension of the mechanisms underlying bacterial co- and cross-resistance to antibiotics and heavy metals.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Drug Resistance, Bacterial ; Metals, Heavy ; Bacteria/genetics ; Environmental Pollutants
    Chemical Substances Anti-Bacterial Agents ; Metals, Heavy ; Environmental Pollutants
    Language English
    Publishing date 2024-04-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 134238-1
    ISSN 1432-0991 ; 0343-8651
    ISSN (online) 1432-0991
    ISSN 0343-8651
    DOI 10.1007/s00284-024-03648-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1446: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Editorial: New drugs, approaches, and strategies to combat antimicrobial resistance.

    Singh, Chandra Kant / Sodhi, Kushneet Kaur / Mubarak, Mohammad S

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1295623

    Language English
    Publishing date 2023-11-06
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1295623
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Understanding the bacterial community structure associated with the Eichhornia crassipes rootzone.

    Singh, Chandra Kant / Sodhi, Kushneet Kaur / Singh, Dileep Kumar

    Molecular biology reports

    2023  Volume 51, Issue 1, Page(s) 35

    Abstract: Background: Plant microbiome acts as an interface between plants and their environment, aiding in the functioning of the ecosystem, such as protection against abiotic and biotic stress along with improving nutrient uptake. The rhizosphere is an ... ...

    Abstract Background: Plant microbiome acts as an interface between plants and their environment, aiding in the functioning of the ecosystem, such as protection against abiotic and biotic stress along with improving nutrient uptake. The rhizosphere is an essential interface for the interaction between plants and microbes and plays a substantial part in the removal as well as uptake of heavy metals and antibiotics from contaminated locations. Eichhornia crassipes is a promising plant that contains a rich community of microbes in its rhizosphere. Microorganism's association with plants embodies a crucial pathway via which humans can also be exposed to antibiotic-resistant genes and bacteria.
    Methods and results: In our earlier study enhanced removal of ciprofloxacin was observed by plant growth-promoting Microbacterium sp. WHC1 in the presence of E. crassipes root exudates. Therefore, the V3-V4, hypervariable region of the 16 S rRNA gene was studied to assess the bacterial diversity and functional profiles of the microbiota associated with plant roots. Using the QIIME software program, 16 S rRNA data from the Next Generation Sequencing (NGS) platform was examined. Alpha diversity including Chao1, Observed Shannon, and Simpson index denote significantly higher bacterial diversity. Proteobacteria (79%) was the most abundant phylum which was present in the root samples followed by Firmicutes (8%) and Cyanobacteria (8%). Sulfuricurvum (36%) is the most abundant genus belonging to the family Helicobacteraceae and the species kujiense in the genus Sulfuricurvum is the most abundant species present in the root sample. Also, the bacterial communities in the rhizoplane of Eichhornia crassipes harbor the genes conferring resistance to beta-lactams, tetracycline, fluoroquinolones, and penams.
    Conclusion: Metagenomic studies on the E. crassipes microbiome showed that the bacterial communities constituting the root exudates of the Eichhornia aid them to survive in a polluted environment.
    MeSH term(s) Humans ; Eichhornia ; Ecosystem ; Anti-Bacterial Agents/metabolism ; Ciprofloxacin ; Fluoroquinolones ; Bacteria/genetics
    Chemical Substances Anti-Bacterial Agents ; Ciprofloxacin (5E8K9I0O4U) ; Fluoroquinolones
    Language English
    Publishing date 2023-12-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-023-08979-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1140: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Whole-genome sequencing of

    Sodhi, Kushneet Kaur / Singh, Chandra Kant / Kumar, Mohit / Singh, Dileep Kumar

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1144561

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-05-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1144561
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Perspective on the heavy metal pollution and recent remediation strategies.

    Sodhi, Kushneet Kaur / Mishra, Lokesh Chandra / Singh, Chandra Kant / Kumar, Mohit

    Current research in microbial sciences

    2022  Volume 3, Page(s) 100166

    Abstract: Heavy metal (HM) pollution is extremely deleterious because of the toxicity they exert on human beings, animals, and plants. HMs are recalcitrant to degradation, and hence persistent in the environment for a longer duration adding to the concern. HMs at ... ...

    Abstract Heavy metal (HM) pollution is extremely deleterious because of the toxicity they exert on human beings, animals, and plants. HMs are recalcitrant to degradation, and hence persistent in the environment for a longer duration adding to the concern. HMs at high concentrations have adverse effects on the production of food as they affect the metabolic activity of plants. HMs have serious implications for human health, reaching the tissue via direct ingestion, dermal contact, inhalation, and adsorption. Several methods have been explored for the eradication of HMs from the environment. Conventional methods of metal removal are constrained by the processing problems, expenses, and the generation of toxic sludge, therefore more research is now focused on the use of bacteria, fungi, plants, and diatoms for the removal of metal ions from the environment. In this context, this review article sheds light on the distribution of HMs in the environment, their sources, and the ecotoxicity they exert on the environment and living beings. The sustainable remedies to decontaminate the environment and the current knowledge and strategies to minimize HM toxicity are also discussed along with the recent developments in the use of nanoparticles and diatoms for HM removal.
    Language English
    Publishing date 2022-09-22
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2666-5174
    ISSN (online) 2666-5174
    DOI 10.1016/j.crmicr.2022.100166
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Basics of economics

    Singh, Chandra Kant, ed

    (Encyclopaedia of advanced economic theroy ; / Dr. Chandra Kant Singh, editor ; volume 1)

    2014  

    Author's details Dr. Chandra Kant Singh, editor
    Series title Encyclopaedia of advanced economic theroy
    / Dr. Chandra Kant Singh, editor ; volume 1
    Language English
    Size vi, 280 Seiten
    Publisher Koros Press Limited
    Publishing place London, UK
    Document type Book
    Note Enthält 6 Beiträge
    Database ECONomics Information System

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  8. Book: Modern economic theory

    Singh, Chandra Kant, ed

    (Encyclopaedia of advanced economic theroy ; / Dr. Chandra Kant Singh, editor ; volume 2)

    2014  

    Author's details Dr. Chandra Kant Singh, editor
    Series title Encyclopaedia of advanced economic theroy
    / Dr. Chandra Kant Singh, editor ; volume 2
    Language English
    Size viii, 271 Seiten
    Publisher Koros Press Limited
    Publishing place London, UK
    Document type Book
    Note Enthält 8 Beiträge
    Database ECONomics Information System

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  9. Book: Theory of international economics

    Singh, Chandra Kant, ed

    (Encyclopaedia of advanced economic theroy ; / Dr. Chandra Kant Singh, editor ; volume 3)

    2014  

    Author's details Dr. Chandra Kant Singh, editor
    Series title Encyclopaedia of advanced economic theroy
    / Dr. Chandra Kant Singh, editor ; volume 3
    Language English
    Size vi, 272 Seiten
    Publisher Koros Press Limited
    Publishing place London, UK
    Document type Book
    Note Enthält 7 Beiträge
    Database ECONomics Information System

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  10. Article: Amyand's Hernia: Rare Presentation of a Common Ailment.

    Singhal, Sanjeev / Singhal, Anu / Negi, Sanjay Singh / Tugnait, Rahul / Arora, Pankaj Kumar / Tiwari, Bishwanath / Malik, Pawan / Gupta, Lav / Bimal, Amit / Gupta, Abhishek / Gupta, Rahul / Chouhan, Pushkar / Singh, ChandraKant

    Case reports in gastrointestinal medicine

    2015  Volume 2015, Page(s) 629127

    Abstract: Inguinal hernia with vermiform appendix as content is known as Amyand's hernia. It is a rare entity but we encountered four cases within six months. A 52-year-old female had high grade fever and evidence of inflammatory pathology involving the ileocaecal ...

    Abstract Inguinal hernia with vermiform appendix as content is known as Amyand's hernia. It is a rare entity but we encountered four cases within six months. A 52-year-old female had high grade fever and evidence of inflammatory pathology involving the ileocaecal region. She was initially managed conservatively and subsequently underwent exploratory laparatomy. The appendix was perforated and herniating in the inguinal canal. Appendectomy was done with herniorrhaphy without mesh placement. A 74-year-old male with bilateral inguinal hernia, of which, the right side was more symptomatic, underwent open exploration. Operative findings revealed a lipoma of the sac and a normal appearing appendix as content. Contents were reduced without appendectomy and mesh hernioplasty was performed. A 63-year-old male with an obstructed right sided hernia underwent emergency inguinal exploration which revealed edematous caecum and appendix as content without any inflammation. Contents were reduced without any resection. Herniorrhaphy was performed without mesh placement. A 66-year-old male with an uncomplicated right inguinal hernia underwent elective surgery. The sac revealed an appendix with adhesions at the neck. Contents were reduced after adhesiolysis and hernioplasty was performed with mesh placement. Emphasis is made to the rarity of disease, variation in presentation, and difference in treatment modalities depending upon the state of appendix.
    Language English
    Publishing date 2015-10-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2627636-7
    ISSN 2090-6536 ; 2090-6528
    ISSN (online) 2090-6536
    ISSN 2090-6528
    DOI 10.1155/2015/629127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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