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Article: Putrescine ameliorates detrimental effects of 2,4-D herbicide on growth and antioxidant enzymes activity of tomato

Singh, Himani / Singh, N. B.

International journal of vegetable science. 2021 July 04, v. 27, no. 4

2021

Abstract: The herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) at higher doses has detrimental effects on tomato (Solanum lycopersicum L.). Putrescine (Put) mitigates 2,4-D induced damage by regulating antioxidants level. Responses of Put-treated tomato to 2,4-D ... ...

Abstract	The herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) at higher doses has detrimental effects on tomato (Solanum lycopersicum L.). Putrescine (Put) mitigates 2,4-D induced damage by regulating antioxidants level. Responses of Put-treated tomato to 2,4-D induced oxidative damage through physiological activities were evaluated. Physiological and biochemical effects of concentrations of 0.5 and 1 mM (D1 and D2) of 2,4-D, with, and without, Put (0.1 mM), were compared. The high dose of 2,4-D caused declines in growth and photosynthetic pigments accompanied by decreased protein, sugar levels, and nitrate reductase (NR) activity compared to untreated plants. The high dose of 2,4-D enhanced accumulation of reactive oxygen species (ROS) with negative effects on lipid, protein contents, and membrane stability. Tomato plants were used to elucidate effects of 2,4-D generated ROS through H₂O₂ (26.9%) and malondialdehyde (MDA) (82.6%) in the plant antioxidant system. The low 2,4-D dose stimulated growth. In the presence of 2,4-D decrease in catalase activity was associated with a higher amount of thiobarbituric acid-reactive substances which cause membrane peroxidation. In Put-treated plants, deleterious effects of 2,4-D were reduced. The Put-treatment might act as a signal that reduces oxidative damage by triggering activity of antioxidant enzymes leading to improved growth and photosynthesis rate.
Keywords	2,4-D ; Solanum lycopersicum ; catalase ; lipids ; malondialdehyde ; nitrate reductase ; peroxidation ; photosynthesis ; putrescine ; sugars ; tomatoes
Language	English
Dates of publication	2021-0704
Size	p. 327-343.
Publishing place	Taylor & Francis
Document type	Article
ZDB-ID	2390923-7
ISSN	1540-7357 ; 1548-1697 ; 1931-5279 ; 1931-5260 ; 1049-6467 ; 1548-1689
ISSN (online)	1540-7357 ; 1548-1697 ; 1931-5279
ISSN	1931-5260 ; 1049-6467 ; 1548-1689
DOI	10.1080/19315260.2020.1793256
Database	NAL-Catalogue (AGRICOLA)

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Article: Encapsulated oil powder: Processing, properties, and applications

Singh, Himani / Kumar, Yogesh / Meghwal, Murlidhar

Journal of food process engineering. 2022 Aug., v. 45, no. 8

2022

Abstract: This review aimed to evaluate the applicability of microencapsulation of different oils (such as fish oil, sunflower oil, soyabean oil, palm oil, flaxseed oil, sesame oil, virgin coconut oil, and rice bran oil) by freeze drying, coacervation, fluidized ... ...

Abstract	This review aimed to evaluate the applicability of microencapsulation of different oils (such as fish oil, sunflower oil, soyabean oil, palm oil, flaxseed oil, sesame oil, virgin coconut oil, and rice bran oil) by freeze drying, coacervation, fluidized bed coating, extrusion, and spray drying. Microencapsulation is the process of creating a functional barrier between the core and the wall material to avoid chemical and physical reactions and maintain the biological, functional, and physicochemical characteristics of the core material. The use of microencapsulated oils (oil powder) in food products provide a significant application in enhancing their functionalities due to the functional benefits of oils. However, utilization of simply oil leads to oxidation and other reactions causing deterioration of finished products quality. Microencapsulated oil has good oxidative stability, thermostability, shelf‐life, and biological activity. Also, microencapsulation helps control the volatility and release properties of essential oils. This review focuses on the role of microencapsulation in increasing the stability, functional properties, and benefits of oils in various food products. PRACTICAL APPLICATION: The comprehensive review on oil powder will be very useful for developing convenient and easily usable oil powder. The oil powder developed will have longer self‐life, stability, and better health benefits. Oil powder can be used as a fortification in meat, dairy, and bakery products to enhance the nutritional value, fatty acids intakes, mouth feel, and textural properties. Such work will help the academic field as well as the industries to develop food products.
Keywords	bioactive properties ; coconut oil ; extrusion ; fish oils ; linseed oil ; meat ; microencapsulation ; mouthfeel ; nutritive value ; oxidation ; oxidative stability ; palm oils ; rice bran oil ; sesame oil ; shelf life ; soybean oil ; sunflower oil ; thermal stability
Language	English
Dates of publication	2022-08
Publishing place	John Wiley & Sons, Inc.
Document type	Article
Note	REVIEW
ZDB-ID	752358-0
ISSN	0145-8876
ISSN	0145-8876
DOI	10.1111/jfpe.14047
Database	NAL-Catalogue (AGRICOLA)

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Article: A Reversible Cause of Cutaneous Rash in a Patient With Alcohol Consumption.

Haider, Asim / Gurjar, Hitesh / Ghazanfar, Haider / Singh, Himani / Siddiqa, Ayesha

Cureus

2023 Volume 15, Issue 2, Page(s) e35011

Abstract: The most common cutaneous manifestations of alcoholism include urticarial reaction, flushing, porphyria cutanea tarda, psoriasis, rosacea, seborrheic dermatitis, and pruritus. Here, we present a case of a young male with a history of alcohol abuse who ... ...

Abstract	The most common cutaneous manifestations of alcoholism include urticarial reaction, flushing, porphyria cutanea tarda, psoriasis, rosacea, seborrheic dermatitis, and pruritus. Here, we present a case of a young male with a history of alcohol abuse who presented with non-blanching, petechial, and perifollicular macular rash secondary to vitamin C deficiency in view of poor oral intake. The rash improved significantly with vitamin C supplementation. Although rare in developed countries, clinicians should keep vitamin C deficiency as a differential diagnosis for skin rash in alcohol consumers.
Language	English
Publishing date	2023-02-15
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.35011
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Submassive Pulmonary Embolism Treated With Catheter-Directed Thrombolysis in Resource-Limited Setting: A Case Report and Review of Literature.

Gurjar, Hitesh / Singh, Himani / Gurjar, Barkha

Cureus

2022 Volume 14, Issue 1, Page(s) e21760

Abstract: We describe a case of a young male who presented with acute onset progressively worsening shortness of breath for four days duration. He used to smoke cigarettes, and his profession required prolonged periods of standing. He underwent a two-dimensional ... ...

Abstract	We describe a case of a young male who presented with acute onset progressively worsening shortness of breath for four days duration. He used to smoke cigarettes, and his profession required prolonged periods of standing. He underwent a two-dimensional echocardiogram showing right ventricular (RV) strain and computed tomography (CT) showing thrombus in the left major pulmonary artery. His pulmonary embolism severity index (PESI) score was high, predicting higher short-term mortality. Treatment options including risks and benefits were discussed with the patient, and he underwent catheter-directed thrombolysis (CDT) with rapid resolution of symptoms, oxygen saturation, and pulmonary artery pressures (PAP). He was discharged home safely after successful treatment of his condition.
Language	English
Publishing date	2022-01-31
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.21760
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A Rare Case Report of Impacted Foreign Body (Sewing Needle) in Upper Neck.

Datta, Ginni / Singh, Gurchand / Singh, Himani / Bhavana, S

Annals of maxillofacial surgery

2022 Volume 12, Issue 1, Page(s) 76–78

Abstract: The rationale: A 19-year-old female presented to the Otorhinolaryngology Department.: Patient concerns: Pain over the right side of the neck below the angle of the mandible following a fall on a pin cushion after a fight with her brother. She ... ...

Abstract	The rationale: A 19-year-old female presented to the Otorhinolaryngology Department. Patient concerns: Pain over the right side of the neck below the angle of the mandible following a fall on a pin cushion after a fight with her brother. She reported that the wound might have been caused by a sewing needle lodged in the pin cushion. Diagnosis: X-ray soft-tissue neck lateral view revealed a radiopaque linear shadow on the right side of the neck at the level of the C1-C2 vertebrae. On contrast-enhanced computed tomography, a linear (needle-like) foreign body at the level of C1-C2 was approximately 1.6 cm deep from the skin. The internal jugular vein seemed to be compressed between the needle and vertebrae. Treatment: Foreign body was explored and removed under general anaesthesia by an open lateral cervical approach. Outcomes: The patient's postoperative recovery was uneventful. Take-away lesson: Due to early diagnosis, management, and a team of experienced surgeons, anaesthesiologists, and support staff, any morbidity or mortality was avoided.
Language	English
Publishing date	2022-08-16
Publishing country	India
Document type	Case Reports
ZDB-ID	2696991-9
ISSN	2249-3816 ; 2231-0746
ISSN (online)	2249-3816
ISSN	2231-0746
DOI	10.4103/ams.ams_63_22
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Physical and thermal properties of various ajwain (Trachyspermum ammi L.) seed varieties as a function of moisture content

Singh, Himani / Meghwal, Murlidhar

Journal of food process engineering. 2020 Feb., v. 43, no. 2

2020

Abstract: Ajwain seeds are used as spice and have high medicinal values. The ajwain seed varieties selected were set at 8, 12, 16, and 20% moisture content on dry basis (db) for this study. The geometrical dimensions showed linear increment with the increase in ... ...

Abstract	Ajwain seeds are used as spice and have high medicinal values. The ajwain seed varieties selected were set at 8, 12, 16, and 20% moisture content on dry basis (db) for this study. The geometrical dimensions showed linear increment with the increase in moisture content of ajwain seeds. The true density and porosity increased from 1,069 to 1,697 kg m−3 and 15.84–42.88%, respectively, across the three varieties of ajwain seeds with the increasing moisture content. The bulk density showed a decreasing trend of 1049.81–857.14 kg m−3 with the increasing moisture content. The coefficient of friction was also found to increase for all the varieties, but the maximum friction was found for the cardboard surface and the minimum friction was observed in case of aluminium sheet. The thermal diffusivity of seeds decreased from 4.09 to 2.46 m2 s−1 with the increasing moisture content. Thermal conductivity and specific heat showed a marked increase with increasing moisture content. Varietal differences among the ajwain seeds of variety AA‐1, AA‐2, and AA‐93 were also studied at 5% significance level. Significant differences were observed between the three ajwain varieties, namely AA‐1, AA‐2, and AA‐93 in context to their physical and thermal properties. PRACTICAL APPLICATIONS: The physical and thermal properties of ajwain seeds will be useful in designing of processes and equipment required for its processing. These properties give detailed information about the quality of the seeds, its acceptability to consumers and the behavior of the ajwain post production, during storage and consumption and post consumption. The knowledge on physical properties such as seed size, shape, volume, surface area, mass, density, porosity helps in designing the separating, storing, handling, and drying systems. The grading and sizing machineries will be based on the size and shape of the ajwian seeds. The density and porosity of the ajwain seeds will help in sizing the hoppers and storage containers. The density of seeds will also play role in separation based on density or specific gravities. The frictional properties like coefficient of friction and angle of repose will help in designing the storage bins, chutes, hoppers, screw conveyers, threshers, and forage harvesters. Thermal properties of ajwain seeds will be useful in analyzing and designing of equipment involving heat transfer, such as in case of cooking, sterilizing and drying.
Keywords	Trachyspermum ammi ; aluminum ; angle of repose ; bins (containers) ; bulk density ; cardboard ; chutes ; conveyors ; cooking ; drying ; forage harvesters ; friction ; heat transfer ; porosity ; seed size ; seeds ; specific gravity ; specific heat ; spices ; sterilizing ; surface area ; thermal conductivity ; thermal diffusivity ; water content
Language	English
Dates of publication	2020-02
Publishing place	John Wiley & Sons, Inc.
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	752358-0
ISSN	0145-8876
ISSN	0145-8876
DOI	10.1111/jfpe.13310
Database	NAL-Catalogue (AGRICOLA)

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Article: Putrescine ameliorates detrimental effects of 2,4-D herbicide on growth and antioxidant enzymes activity of tomato

Singh, Himani / Singh, N. B.

International journal of vegetable science

2021 Volume 27, Issue 1/6, Page(s) 327

Language	English
Document type	Article
ZDB-ID	2390923-7
ISSN	1931-5260
Database	Current Contents Nutrition, Environment, Agriculture

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Article ; Online: Lipid-Based Nanocarriers in the Treatment of Glioblastoma Multiforme (GBM): Challenges and Opportunities.

Gupta, Tanisha / Sahoo, Rakesh K / Singh, Himani / Katke, Sumeet / Chaurasiya, Akash / Gupta, Umesh

AAPS PharmSciTech

2023 Volume 24, Issue 4, Page(s) 102

Abstract: Glioblastoma multiforme (also known as glioblastoma; GBM) is one of the most malignant types of brain tumors that occurs in the CNS. Treatment strategies for glioblastoma are majorly comprised of surgical resection, radiotherapy, and chemotherapy along ... ...

Abstract	Glioblastoma multiforme (also known as glioblastoma; GBM) is one of the most malignant types of brain tumors that occurs in the CNS. Treatment strategies for glioblastoma are majorly comprised of surgical resection, radiotherapy, and chemotherapy along with combination therapy. Treatment of GBM is itself a tedious task but the involved barriers in GBM are one of the main impediments to move one step closer to the treatment of GBM. Basically, two of the barriers are of utmost importance in this regard, namely blood brain barrier (BBB) and blood brain tumor barrier (BBTB). This review will address different challenges and barriers in the treatment of GBM along with their etiology. The role and recent progress of lipid-based nanocarriers like liposomes, solid lipid nanocarriers (SLNs), nanostructured lipid carriers (NLCs), lipoplexes, and lipid hybrid carriers in the effective management of GBM will be discussed in detail.
MeSH term(s)	Humans ; Glioblastoma/drug therapy ; Drug Delivery Systems ; Drug Carriers/therapeutic use ; Brain Neoplasms/drug therapy ; Lipids
Chemical Substances	Drug Carriers ; Lipids
Language	English
Publishing date	2023-04-11
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2052070-0
ISSN	1530-9932 ; 1530-9932
ISSN (online)	1530-9932
ISSN	1530-9932
DOI	10.1208/s12249-023-02555-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Modulation of inflammatory and oxidative stress biomarkers due to dexamethasone exposure in chicken splenocytes

Ambwani, Sonu / Dolma, Rigzin / Sharma, Raunak / Kaur, Amandip / Singh, Himani / Ruj, Anamitra / Ambwani, Tanuj Kumar

Veterinary Immunology and Immunopathology. 2023 Aug., v. 262 p.110632-

2023

Abstract: Dexamethasone (DEXA) is a potent corticosteroid, commonly used for treating inflammatory, hypersensitive and allergic conditions. It is administered to birds with tumours. Many studies were conducted on its immunosuppressive effects; however none of the ... ...

Abstract	Dexamethasone (DEXA) is a potent corticosteroid, commonly used for treating inflammatory, hypersensitive and allergic conditions. It is administered to birds with tumours. Many studies were conducted on its immunosuppressive effects; however none of the similar study is available employing chicken splenocytes culture system. The present study was conducted to assess DEXA induced alterations in inflammatory and oxidative stress biomarkers in chicken splenocytes due to its in vitro exposure. The maximum non-cytotoxic dose (MNCD) was evaluated and was further used for conducting lymphocytes proliferation assay (LPA), antioxidant assays (lipid peroxidation, GSH, superoxide dismutase and nitric oxide assays) and assessment of mRNA levels of various genes (IL-1β, IL-6, IL-10, LITAF, iNOS, NF-κB1, Nrf-2, Caspase-3 and -9) through qPCR. The MNCD was determined to be 30 ng/ml in chicken splenocytes culture system. DEXA caused reduction in B and T lymphocytes proliferation indicating its immunosuppressive effects, however improved the antioxidant status of the exposed splenocytes. The expression levels of IL-1β, IL-6, iNOS, LITAF and NF-κB1 were significantly reduced while IL-10 was enhanced, which signify potent anti-inflammatory potential of DEXA. NF-κB is a major transcription factor that regulates genes responsible for both, innate and adaptive immune responses and elicits inflammation. The nuclear factor erythroid 2-related factor 2 (Nrf-2) level was found to be up-regulated. Nrf-2 plays important role in combating the oxidant stress and its increased expression could be the reason of improved antioxidant status of DEXA exposed cells. Present findings indicated that DEXA exhibited modulation in anti-inflammatory, immunomodulatory and antioxidant mediators in chicken splenocytes.
Keywords	adrenal cortex hormones ; anti-inflammatory activity ; antioxidants ; biomarkers ; caspase-3 ; chickens ; dexamethasone ; immunopathology ; immunosuppression ; inflammation ; interleukin-10 ; interleukin-6 ; lipid peroxidation ; nitric oxide ; oxidants ; oxidative stress ; splenocytes ; superoxide dismutase ; transcription factors ; Glucocorticoids ; Chicken ; Cytokines ; Nrf-2 ; Antioxidant ; iNOS
Language	English
Dates of publication	2023-08
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	754160-0
ISSN	1873-2534 ; 0165-2427
ISSN (online)	1873-2534
ISSN	0165-2427
DOI	10.1016/j.vetimm.2023.110632
Database	NAL-Catalogue (AGRICOLA)

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Article: Grinding characteristics and energy consumption in cryogenic and ambient grinding of ajwain seeds at varied moisture contents

Singh, Himani / Meghwal, Murlidhar / Prabhakar, Pramod K. / Kumar, Nitin

Powder technology. 2022 June, v. 405

2022

Abstract: The study on cryogenic and ambient grinding of ajwain seeds was envisaged to understand the energy consumption pattern during different grinding processes as a function of moisture content 8, 12, 16 and 20% (db) for AA-1, AA-2 and AA-93 varieties of ... ...

Abstract	The study on cryogenic and ambient grinding of ajwain seeds was envisaged to understand the energy consumption pattern during different grinding processes as a function of moisture content 8, 12, 16 and 20% (db) for AA-1, AA-2 and AA-93 varieties of ajwain seeds. The grinding time was found to increase from 57.6 ± 0.01 to 180 ± 0.08 s, whereas feed rate was found to decrease from 6.25 ± 0.07 to 2.00 ± 0.12 kg h⁻¹ with the increasing moisture content. This resulted in more power consumption ranging from 0.012 ± 0.08 to 0.037 ± 0.007 kW h⁻¹ in all the ajwain varieties for the selected moisture range under cryogenic and ambient grinding conditions. But the specific energy consumption was found to be higher in case of ambient grinding conditions. Also, the various energy models such as Kick's, Rittinger's and Bond's work index were found to increase significantly (p < 0.05) with increasing moisture content ranging from 1.02 to 13.22 kJ kg⁻¹, 0.55 to 21.92 kJ kg⁻¹ and 15.31 to 195.31 kJ kg⁻¹, respectively. The cryogenic grinding was found to be more energy efficient than ambient grinding. Moreover, cryogenic grinding results in more yield and good quality product with uniform particle size distribution and lower powder density. This study will help the food processing industries while grinding spices and for designing of appropriate grinder specifically for grinding ajwain seeds.
Keywords	energy efficiency ; energy use and consumption ; particle size distribution ; specific energy ; water content
Language	English
Dates of publication	2022-06
Publishing place	Elsevier B.V.
Document type	Article
ISSN	0032-5910
DOI	10.1016/j.powtec.2022.117531
Database	NAL-Catalogue (AGRICOLA)

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