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  1. Article ; Online: Balancing risks and benefits: nuisance medication and cognitive decline in late-life.

    Karp, Jordan F / Erisman, Matthew / Singh, Jasmine

    International psychogeriatrics

    2023  Volume 36, Issue 2, Page(s) 89–91

    MeSH term(s) Humans ; Cognitive Dysfunction/drug therapy ; Risk Factors
    Language English
    Publishing date 2023-06-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1038825-4
    ISSN 1741-203X ; 1041-6102
    ISSN (online) 1741-203X
    ISSN 1041-6102
    DOI 10.1017/S1041610223000534
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Two Puzzling Cases of Headache: A Case Series

    Singh, Jasmine / Azad, Chandrika

    Journal of Pediatric Neurology

    2023  

    Abstract: Migraine and epilepsy are important causes of morbidity in adolescents and young adults. Mostly the diagnosis is readily made by using the predefined criteria. However, in extremely rare cases, children who present with typical symptoms of migraine with ... ...

    Abstract Migraine and epilepsy are important causes of morbidity in adolescents and young adults. Mostly the diagnosis is readily made by using the predefined criteria. However, in extremely rare cases, children who present with typical symptoms of migraine with aura or familial hemiplegic migraine might have an underlying etiology of epilepsy. We hereby present the case of two children who presented with migraine-like symptoms but on detailed workup revealed an underlying epilepsy. Both patients responded to antiepileptic medications. These cases highlight the importance of a detailed history and comprehensive investigation plan for such patients to prevent erroneous diagnosis and migraine prophylaxis.
    Keywords headache ; migraine ; epilepsy ; seizures ; migralepsy
    Language English
    Publishing date 2023-07-28
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ISSN 1875-9041 ; 1304-2580
    ISSN (online) 1875-9041
    ISSN 1304-2580
    DOI 10.1055/s-0043-1771351
    Database Thieme publisher's database

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  3. Article: Adrenocorticotropic Hormone Induced Status Dystonicus in a Child with West Syndrome.

    Singh, Jasmine / Aulakh, Roosy

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2021  Volume 26, Issue 8, Page(s) 961–962

    Abstract: Dystonia is a movement disorder characterized by involuntary sustained or intermittent muscle contraction causing repetitive twisting movements and abnormal postures. Status dystonicus (SD) is an enigmatic disease of cryptic etiology. We hereby report a ... ...

    Abstract Dystonia is a movement disorder characterized by involuntary sustained or intermittent muscle contraction causing repetitive twisting movements and abnormal postures. Status dystonicus (SD) is an enigmatic disease of cryptic etiology. We hereby report a child with West syndrome (WS) who went on to develop SD following intramuscular adrenocorticotropic hormone (ACTH) injection. An 11-month-old male child presented with complaints of flexor spasms for 2 months. The diagnosis of WS was confirmed by electroencephalography (EEG), which showed hypsarrhythmia. Intramuscular ACTH was added, and oral trihexyphenidyl was started for dystonia. On day 7 of ACTH, the child developed frequent opisthotonic posturing. Management protocol for grade IV SD was initiated. Administration of N-terminal of ACTH in rat locus coeruleus has been shown to produce human dystonia-like movement and abnormal posturing.
    How to cite this article: Singh J, Aulakh R. Adrenocorticotropic Hormone Induced Status Dystonicus in a Child with West Syndrome. Indian J Crit Care Med 2022;26(8):961-962.
    Language English
    Publishing date 2021-01-30
    Publishing country India
    Document type Case Reports
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-24289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Acute demyelinating encephalomyelitis in a child with pulmonary tuberculosis.

    Singh, Jasmine / Sharma, Pallavi / Randev, Shivani / Kaur, Narinder / Kumar, Pankaj / Guglani, Vishal

    Paediatrics and international child health

    2024  , Page(s) 1–3

    Abstract: Tuberculosis is a leading cause of mortality in children worldwide. One of the greatest challenges in its management is the difficulty of diagnosis as the manifestations are non-specific and often mimic other illnesses. Neurological infection occurs in ... ...

    Abstract Tuberculosis is a leading cause of mortality in children worldwide. One of the greatest challenges in its management is the difficulty of diagnosis as the manifestations are non-specific and often mimic other illnesses. Neurological infection occurs in approximately 1% of patients diagnosed with tuberculosis, and usually takes the form of tuberculous meningitis or tuberculoma. An 11-year-old girl who was diagnosed with acute disseminated encephalomyelitis, a rare immunological manifestation of tuberculosis, is presented. She recovered completely after a course of high-dose systemic corticosteroids in addition to anti-tuberculosis treatment. Considering the immense burden of this infectious disease, recognition and understanding of the uncommon manifestations are important to enable appropriate and timely treatment.
    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2649065-1
    ISSN 2046-9055 ; 2046-9047
    ISSN (online) 2046-9055
    ISSN 2046-9047
    DOI 10.1080/20469047.2024.2335422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Spontaneous bacterial peritonitis: A rare manifestation of expanded dengue syndrome.

    Kaur, Jaspreet / Singh, Jasmine / Cheema, Yuvraj Singh

    Turkish journal of emergency medicine

    2022  Volume 23, Issue 3, Page(s) 188–190

    Abstract: Abdominal pain is a usual presentation in dengue virus infection. The commonly reported causes of abdominal pain in dengue fever are pancreatitis, peptic ulcer disease, hepatitis, and acalculous cholecystitis. Spontaneous bacterial peritonitis (SBP) is a ...

    Abstract Abdominal pain is a usual presentation in dengue virus infection. The commonly reported causes of abdominal pain in dengue fever are pancreatitis, peptic ulcer disease, hepatitis, and acalculous cholecystitis. Spontaneous bacterial peritonitis (SBP) is a very unusual and rarely reported cause. The etiology of the acute abdomen along with nonresolving fever in dengue infection should be carefully diagnosed and managed accordingly. We report the case of a young female with no previous comorbidities who presented with complaints of fever and abdominal pain. On detailed investigations, she was diagnosed suffering from SBP, a rare type of expanded dengue syndrome.
    Language English
    Publishing date 2022-09-28
    Publishing country India
    Document type Case Reports
    ISSN 2452-2473
    ISSN 2452-2473
    DOI 10.4103/2452-2473.357336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Peripheral Perfusion Index as a Marker of Sepsis in Preterm Neonates.

    Singh, Jasmine / Jain, Suksham / Chawla, Deepak / Randev, Shivani / Khurana, Supreet

    Journal of tropical pediatrics

    2022  Volume 68, Issue 2

    Abstract: Background: Neonatal sepsis is a major contributor to neonatal mortality in India. Blood culture, the gold standard for the diagnosis of sepsis takes 48-72 h while the serological markers have suboptimal diagnostic test characteristics. Perfusion index ( ...

    Abstract Background: Neonatal sepsis is a major contributor to neonatal mortality in India. Blood culture, the gold standard for the diagnosis of sepsis takes 48-72 h while the serological markers have suboptimal diagnostic test characteristics. Perfusion index (PI) is a real time, non-invasive marker that can detect microcirculatory changes before other clinical manifestation of sepsis.
    Objective: To determine the diagnostic accuracy of PI in detecting hospital-acquired sepsis before overt clinical manifestations.
    Study design: A prospective observational study conducted in the Neonatal Intensive Care Unit (NICU) of a tertiary care hospital.
    Participants: Preterm neonates admitted to NICU.
    Methods: PI was continuously monitored in all enrolled neonates. Clinical sepsis was defined using the NeonatalKrankenhaus-Infektions-Surveillance-System (NeoKISS). The time of fall of PI below 0.88 and time of clinical sepsis as per NeoKISS were noted and the difference was calculated.
    Results: Among 65 preterm neonates (gestational age: 31.5 ± 2.6 weeks, birth weight: 1350, IQR 1100-1700 g), a total of 86 events of suspected sepsis were noted, of which 69 were sepsis screen positive. Fifteen events were associated with culture positive sepsis. PI yielded a sensitivity of 89.47% (95% CI 78.48-96.04%), specificity of 56% (95% CI 34.93-75.60%), positive predictive value of 82.26% (95% CI 74.70-87.92%) and negative predictive value of 70% (95% CI 50.36-84.29%) in detection of hospital-acquired sepsis.
    Conclusion: PI might serve as an early, non-invasive marker of hospital-acquired sepsis in preterm neonates.
    MeSH term(s) Biomarkers ; Humans ; Infant ; Infant, Newborn ; Intensive Care Units, Neonatal ; Microcirculation ; Perfusion Index ; Sepsis/diagnosis
    Chemical Substances Biomarkers
    Language English
    Publishing date 2022-02-11
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 800065-7
    ISSN 1465-3664 ; 0449-3281 ; 0142-6338
    ISSN (online) 1465-3664
    ISSN 0449-3281 ; 0142-6338
    DOI 10.1093/tropej/fmac014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: Single-shot Quantum Signal Processing Interferometry

    Sinanan-Singh, Jasmine / Mintzer, Gabriel L. / Chuang, Isaac L. / Liu, Yuan

    2023  

    Abstract: Quantum systems of infinite dimension, such as bosonic oscillators, provide vast resources for quantum sensing. Yet, a general theory on how to manipulate such bosonic modes for sensing beyond parameter estimation is unknown. We present a general ... ...

    Abstract Quantum systems of infinite dimension, such as bosonic oscillators, provide vast resources for quantum sensing. Yet, a general theory on how to manipulate such bosonic modes for sensing beyond parameter estimation is unknown. We present a general algorithmic framework, quantum signal processing interferometry (QSPI), for quantum sensing at the fundamental limits of quantum mechanics, i.e., the Heisenberg sensing limit, by generalizing Ramsey-type interferometry. Our QSPI sensing protocol relies on performing nonlinear polynomial transformations on the oscillator's quadrature operators by generalizing quantum signal processing (QSP) from qubits to hybrid qubit-oscillator systems. We use our QSPI sensing framework to make binary decisions on a displacement channel in the single-shot limit. Theoretical analysis suggests the sensing accuracy given a single-shot qubit measurement can approach the Heisenberg-limit scaling. We further concatenate a series of such binary decisions to perform parameter estimation in a bit-by-bit fashion. Numerical simulations are performed to support these statements. Our QSPI protocol offers a unified framework for quantum sensing using continuous-variable bosonic systems beyond parameter estimation and establishes a promising avenue toward efficient and scalable quantum control and quantum sensing schemes beyond the NISQ era.

    Comment: 20 pages, 8 figures, 1 table
    Keywords Quantum Physics ; Electrical Engineering and Systems Science - Signal Processing
    Subject code 539
    Publishing date 2023-11-22
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: The “Blast” Behind Jerky Eyes

    Singh, Jasmine / Randev, Shivani / Azad, Chandrika / Kaur, Harkirat / Guglani, Vishal

    Indian Journal of Medical and Paediatric Oncology

    (Special Issue: Imaging Guidelines: Part—2)

    2023  Volume 44, Issue 03, Page(s) 353–355

    Abstract: Opsoclonus is defined as hyperkinetic, omnidirectional, spontaneous, and involuntary chaotic eye movements. Opsoclonus-myoclonus-ataxia syndrome is addressed by many names including “dancing eyes-dancing feet syndrome,” “Kinsbourne syndrome,” and “ ... ...

    Series title Special Issue: Imaging Guidelines: Part—2
    Abstract Opsoclonus is defined as hyperkinetic, omnidirectional, spontaneous, and involuntary chaotic eye movements. Opsoclonus-myoclonus-ataxia syndrome is addressed by many names including “dancing eyes-dancing feet syndrome,” “Kinsbourne syndrome,” and “infantile polymyoclonia.” The early accounts of the clinical syndrome date back to 1962 when Marcel Kinsbourne described six cases of this phenotype. However, it was not until 1968 the association with occult neuroblastoma was first reported. We report the video of a 1-year-old boy who presented with this syndrome for a duration of 3 months. He was diagnosed to have an abdominal neuroblastoma and was treated with resection of the tumor and administration of intramuscular adrenocorticotropic hormone. He showed complete resolution of symptoms. The syndrome is difficult to recognize and might be confused with seizures, tremors, or chorea; hence, it is important that residents learnt to recognize this syndrome and look for an underlying tumor actively.
    Keywords neuroblastoma ; paraneoplastic syndrome ; opsoclonus-myoclonus-ataxia syndrome
    Language English
    Publishing date 2023-05-12
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2181724-8
    ISSN 0975-2129 ; 0971-5851 ; 0975-2129
    ISSN (online) 0975-2129
    ISSN 0971-5851 ; 0975-2129
    DOI 10.1055/s-0043-1761264
    Database Thieme publisher's database

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  9. Article ; Online: Infantile Tremor Syndrome Followed by West Syndrome: Effect or Continuation of Spectrum?

    Azad, Chandrika / Singh, Jasmine / Guglani, Vishal

    Journal of tropical pediatrics

    2020  Volume 66, Issue 5, Page(s) 556–560

    Abstract: Background: Infantile tremor syndrome (ITS) is a nutritional deficiency syndrome, frequently reported from the Indian subcontinent caused by vitamin B12 deficiency. The West syndrome (WS), on the other hand, is a type of epileptic encephalopathy with ... ...

    Abstract Background: Infantile tremor syndrome (ITS) is a nutritional deficiency syndrome, frequently reported from the Indian subcontinent caused by vitamin B12 deficiency. The West syndrome (WS), on the other hand, is a type of epileptic encephalopathy with variable etiology.
    Case series: We present a series of five children who presented with symptoms consistent with ITS and received standard intramuscular vitamin B12 therapy to which good response was observed. All these children were readmitted with WS with a time lag varying from 2 to 12 months. Magnetic resonance imaging brain and metabolic screen were within normal limits. Three out of five patients responded well to adrenocorticotropic hormone (ACTH), remaining two required additional drugs. We hypothesize that WS could have developed after ITS due to developmental desynchronization.
    Conclusion: In the Indian scenario, it is particularly important to be aware of appearance of WS after ITS, because of high prevalence of ITS and devastating nature of WS.
    MeSH term(s) Adrenocorticotropic Hormone/therapeutic use ; Brain/diagnostic imaging ; Child ; Humans ; Infant ; Injections, Intramuscular ; Magnetic Resonance Imaging ; Spasms, Infantile/diagnosis ; Spasms, Infantile/drug therapy ; Spasms, Infantile/etiology ; Syndrome ; Tremor/drug therapy ; Tremor/etiology ; Vitamin B 12/administration & dosage ; Vitamin B 12/therapeutic use ; Vitamin B 12 Deficiency/drug therapy
    Chemical Substances Adrenocorticotropic Hormone (9002-60-2) ; Vitamin B 12 (P6YC3EG204)
    Language English
    Publishing date 2020-03-31
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 800065-7
    ISSN 1465-3664 ; 0449-3281 ; 0142-6338
    ISSN (online) 1465-3664
    ISSN 0449-3281 ; 0142-6338
    DOI 10.1093/tropej/fmaa014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: History and Epidemiology of Cancer Pain.

    Copenhaver, David J / Huang, Ming / Singh, Jasmine / Fishman, Scott M

    Cancer treatment and research

    2021  Volume 182, Page(s) 3–15

    Abstract: Pain is indelibly associated with the cancer experience. A systematic review and meta-analysis indicate that the prevalence of cancer pain is 55% during anticancer treatment, 66.4% in advanced, metastatic, or terminal disease, and 39.3% after curative ... ...

    Abstract Pain is indelibly associated with the cancer experience. A systematic review and meta-analysis indicate that the prevalence of cancer pain is 55% during anticancer treatment, 66.4% in advanced, metastatic, or terminal disease, and 39.3% after curative treatment.
    MeSH term(s) Cancer Pain/epidemiology ; Cancer Pain/etiology ; Humans ; Neoplasms/complications ; Neoplasms/epidemiology ; Prevalence
    Language English
    Publishing date 2021-09-20
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ISSN 0927-3042
    ISSN 0927-3042
    DOI 10.1007/978-3-030-81526-4_1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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