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  1. Article ; Online: Correction: Visible-light acridinium-based organophotoredox catalysis in late-stage synthetic applications.

    Singh, Praveen P / Singh, Jaya / Srivastava, Vishal

    RSC advances

    2024  Volume 14, Issue 8, Page(s) 5600

    Abstract: This corrects the article DOI: 10.1039/D3RA01364B.]. ...

    Abstract [This corrects the article DOI: 10.1039/D3RA01364B.].
    Language English
    Publishing date 2024-02-13
    Publishing country England
    Document type Published Erratum
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d4ra90011a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Trios Lidisi Veneer, Transforming Smiles Using an Intraoral Scanner - A Case Report.

    Pandey, Laxmi / Bhatt, Akanksha / Samant, Praveen Singh / Singh, Jaya

    Indian journal of dental research : official publication of Indian Society for Dental Research

    2024  Volume 34, Issue 4, Page(s) 461–463

    Abstract: Introduction: The need to perform restorations with a natural appearance is one of the most challenging aspects of dentistry, and reproducing the colour of natural teeth in restorations is a clinical challenge due to the complex optical characteristics ... ...

    Abstract Introduction: The need to perform restorations with a natural appearance is one of the most challenging aspects of dentistry, and reproducing the colour of natural teeth in restorations is a clinical challenge due to the complex optical characteristics of dentition. Various procedures have been advocated in the literature to correct dental anomalies, particularly in the aesthetic region, such as tooth discoloration due to fluorosis or dentition spacing due to changes in tooth shape, such as peg laterals.
    Clinical applications: Veneer are one of the most commonly used treatment modalities in such cases. As the use of ceramics necessitates the use of more opaque restorative materials or different thickness, obtaining adequate results in terms of the final colour of the restoration becomes increasingly difficult. The purpose of this study is to present a clinical case of smile rehabilitation in the anterior region with facets made of lithium disilicate, with the goal of achieving colour uniformity and demonstrating the benefits and achieving smile aesthetics.
    Takeaway lessons: Technological advancement such as intraoral scanner for impression making have significant improved the success of prosthesis. This case report presents conservative and aesthetic procedure in the management of closing the space in maxillary anterior region using lithium disilicate laminate veneers with trios software.
    MeSH term(s) Humans ; Dental Veneers ; Esthetics, Dental ; Dental Porcelain ; Smiling ; Female ; Adult ; Dental Prosthesis Design ; Computer-Aided Design
    Chemical Substances Dental Porcelain (12001-21-7) ; lithia disilicate
    Language English
    Publishing date 2024-04-19
    Publishing country India
    Document type Case Reports ; Journal Article
    ZDB-ID 1354886-4
    ISSN 1998-3603 ; 0970-9290
    ISSN (online) 1998-3603
    ISSN 0970-9290
    DOI 10.4103/ijdr.ijdr_430_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Visible-light acridinium-based organophotoredox catalysis in late-stage synthetic applications.

    Singh, Praveen P / Singh, Jaya / Srivastava, Vishal

    RSC advances

    2023  Volume 13, Issue 16, Page(s) 10958–10986

    Abstract: The field of photoredox catalysis has been transformed by the use of organic photocatalysts, which give access to re-activities that were previously only possible with transition-metal photocatalysts. Recent advancements in the use of an acridinium ... ...

    Abstract The field of photoredox catalysis has been transformed by the use of organic photocatalysts, which give access to re-activities that were previously only possible with transition-metal photocatalysts. Recent advancements in the use of an acridinium photocatalyst in organic synthesis are covered in this review. Both the late-stage functionalization of biorelevant molecules and the activation of inert chemical bonds are explored, with an emphasis on their mechanistic features.
    Language English
    Publishing date 2023-04-06
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra01364b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Oncocytoma of the parotid gland: A rare benign tumour.

    Singh, Jaya / Chandra, Akhilesh / Srilatha, Tumpuri / Jain, Trupti / Raja, Dinesh / Agrawal, Rahul

    Journal of oral and maxillofacial pathology : JOMFP

    2023  Volume 27, Issue Suppl 1, Page(s) S41–S44

    Abstract: Oncocytomas are one of the infrequent neoplasms seen in the oral cavity accounting for less than 2% of all neoplasms in the oral cavity with less than 1% chance of malignant transformation. They affect the major salivary glands and have a female ... ...

    Abstract Oncocytomas are one of the infrequent neoplasms seen in the oral cavity accounting for less than 2% of all neoplasms in the oral cavity with less than 1% chance of malignant transformation. They affect the major salivary glands and have a female predilection. The cognisance of the unique clinical and histopathological features is very important to conclude a confirmatory diagnosis. This paper reviews a case of oncocytoma presented in our department and also elucidates the diagnostic criteria for the same.
    Language English
    Publishing date 2023-02-04
    Publishing country India
    Document type Case Reports
    ZDB-ID 2390999-7
    ISSN 1998-393X ; 0973-029X
    ISSN (online) 1998-393X
    ISSN 0973-029X
    DOI 10.4103/jomfp.jomfp_437_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Molecular machinery regulating mitochondrial calcium levels: The nuts and bolts of mitochondrial calcium dynamics.

    Tanwar, Jyoti / Singh, Jaya Bharti / Motiani, Rajender K

    Mitochondrion

    2020  Volume 57, Page(s) 9–22

    Abstract: Mitochondria play vital role in regulating the cellular energetics and metabolism. Further, it is a signaling hub for cell survival and apoptotic pathways. One of the key determinants that calibrate both cellular energetics and survival functions is ... ...

    Abstract Mitochondria play vital role in regulating the cellular energetics and metabolism. Further, it is a signaling hub for cell survival and apoptotic pathways. One of the key determinants that calibrate both cellular energetics and survival functions is mitochondrial calcium (Ca
    MeSH term(s) Calcium/metabolism ; Citric Acid Cycle ; Cytochromes c/metabolism ; Gene Expression Regulation ; Humans ; Mitochondria/metabolism ; Mitochondrial Permeability Transition Pore/metabolism ; Mitochondrial Proteins/metabolism ; Reactive Oxygen Species/metabolism
    Chemical Substances Mitochondrial Permeability Transition Pore ; Mitochondrial Proteins ; Reactive Oxygen Species ; Cytochromes c (9007-43-6) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2020-12-11
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2056923-3
    ISSN 1872-8278 ; 1567-7249
    ISSN (online) 1872-8278
    ISSN 1567-7249
    DOI 10.1016/j.mito.2020.12.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Evaluation of salivary oxidative stress in oral lichen planus using malonaldehyde.

    Singh, Shruti / Singh, Jaya / Biradar, Basavaprabhu C / Sonam, Manjari / Chandra, Shaleen / Samadi, Fahad M

    Journal of oral and maxillofacial pathology : JOMFP

    2022  Volume 26, Issue 1, Page(s) 26–30

    Abstract: Background: Oral lichen planus is a chronic, mucocutaneous, inflammatory disease, with an unknown etiology. Reactive oxygen species and oxidative damage to the tissues might be the cause. Malonaldehyde (MDA), a low molecular weight end product of lipid ... ...

    Abstract Background: Oral lichen planus is a chronic, mucocutaneous, inflammatory disease, with an unknown etiology. Reactive oxygen species and oxidative damage to the tissues might be the cause. Malonaldehyde (MDA), a low molecular weight end product of lipid peroxidation reaction is a suitable biomarker of endogenous DNA damage. monitoring the oxidant-antioxidant status of saliva may serve as an efficient marker of disease development in oral lichen planus patients.
    Aim and objectives: To evaluate salivary oxidative stress in oral lichen planus subject using MDA and compare it with control subjects. Furthermore, to compare MDA levels in erosive and hypertrophic lichen planus.
    Materials and methods: The current study is case-control study. Unstimulated salivary samples in the morning hours were taken from oral lichen planus subjects (
    Results: The data were expressed as the mean ± standard deviation and the statistical analysis was done using Student's
    Conclusion: The higher level of MDA in patients with oral lichen planus suggests that free radicals and the resulting oxidative damage may be important in the pathogenesis of oral lichen planus lesions.
    Language English
    Publishing date 2022-03-31
    Publishing country India
    Document type Journal Article
    ZDB-ID 2390999-7
    ISSN 1998-393X ; 0973-029X
    ISSN (online) 1998-393X
    ISSN 0973-029X
    DOI 10.4103/jomfp.jomfp_333_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Attitudes Of Recently Admitted Undergraduate Medical Students Towards Learning Communication-Skills: A Cross-Sectional Study From Chitwan Medical College.

    Timilsina, Sameer / Karki, Sirisa / Singh, Jaya Prasad

    Advances in medical education and practice

    2019  Volume 10, Page(s) 963–969

    Abstract: Background and purpose: The success story of a modern-day physician centers substantially on the knowledge of proper communication-skills with patients and their bedside relatives. Therefore, it has become extremely important to start a communication- ... ...

    Abstract Background and purpose: The success story of a modern-day physician centers substantially on the knowledge of proper communication-skills with patients and their bedside relatives. Therefore, it has become extremely important to start a communication-skills course early on in undergraduate medical study, but to date, this has been given relatively little or no emphasis. In the present study, an attempt was made to assess the attitude of undergraduate medical newbies towards learning communication-skills, and the association between attitude and various student characteristics.
    Patients and methods: A total of 99 recently admitted undergraduate medical students at Chitwan Medical College were included in the study, and their attitude towards communication-skills training was measured using the Communication Skills Attitude Scale (CSAS).
    Results: A positive learning attitude was found in over 50% of participants. The idea of a requirement of communication-skills curriculum was associated with a positive learning attitude. Gender, age, and past educational institute were not associated with communication skills learning attitude.
    Conclusion: This study provides perceptions of newly admitted undergraduate medical students towards communication-skills learning. We suggest the integration of communication-skills curriculum into the undergraduate medical syllabus, with an acceptable, focused, and interesting teaching module.
    Language English
    Publishing date 2019-11-15
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2578539-4
    ISSN 1179-7258
    ISSN 1179-7258
    DOI 10.2147/AMEP.S229951
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Prevalence of oral cancer and oral epithelial dysplasia among North Indian population: A retrospective institutional study.

    Singh, Shruti / Singh, Jaya / Chandra, Shaleen / Samadi, Fahad Mansoor

    Journal of oral and maxillofacial pathology : JOMFP

    2020  Volume 24, Issue 1, Page(s) 87–92

    Abstract: Background: Despite our sincere and serious efforts, oral cancer (particularly oral squamous cell carcinoma [OSCC]) is the major cause of morbidity and mortality in the Indian population. Oral precancerous lesions show quite high malignant ... ...

    Abstract Background: Despite our sincere and serious efforts, oral cancer (particularly oral squamous cell carcinoma [OSCC]) is the major cause of morbidity and mortality in the Indian population. Oral precancerous lesions show quite high malignant transformation rate. Epidemiological data of oral epithelial dysplasia (OED) and OSCC could help in early diagnosis and thus may improve the prognosis. The current study aims to retrospectively analyze the epidemiological profile of patients with different grades of OED and OSCCs.
    Materials and methods: The current study is a retrospective analysis of OED and OSCC reported in 5 years in our institution from 2014 to 2018. Data for the analysis were attained from the case sheets from the patients diagnosed with OED and OSCC.
    Results: The mean prevalence of OED and OSCC was 5.71% and 9.85%, respectively. Among the dysplastic lesions, severe dysplasia was more common, while well-differentiated squamous cell carcinoma was more common among the carcinomatous lesions. The peak age prevalence of both the lesions was third to fifth decade. Males were more frequently affected than females, with buccal mucosa being the most common site.
    Conclusion: The data attained from this study highlight the need for community-based screening and awareness programs for general population and thus obtain a healthier society.
    Language English
    Publishing date 2020-05-08
    Publishing country India
    Document type Journal Article
    ZDB-ID 2390999-7
    ISSN 1998-393X ; 0973-029X
    ISSN (online) 1998-393X
    ISSN 0973-029X
    DOI 10.4103/jomfp.JOMFP_347_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Expression of β-catenin in oral leukoplakia and oral submucous fibrosis: An immunohistochemical study.

    Chowdhury, Pritha / Nagamalini, B R / Singh, Jaya / Ashwini, B K / Sharada / Swaminathan, Uma

    Journal of oral and maxillofacial pathology : JOMFP

    2021  Volume 25, Issue 1, Page(s) 124–130

    Abstract: Background: Oral potentially malignant disorders have increased propensity to turn malignant than its apparently normal counterparts. Histopathological examination, although gold standard, needs adjunct technique to give accurate diagnosis. ... ...

    Abstract Background: Oral potentially malignant disorders have increased propensity to turn malignant than its apparently normal counterparts. Histopathological examination, although gold standard, needs adjunct technique to give accurate diagnosis. Immunohistochemistry has proved to be a promising adjunct to aid in the diagnosis so far. The quest for a definitive marker is still on. Beta-catenin (β-catenin), a structural protein has been evaluated to identify its likely role in malignant transformation of potentially malignant lesions and possibly designate it as one of the identifiable signature molecules in the transformation.
    Aim and objective: To evaluate and estimate the expression of β-catenin in different grades of dysplasia, oral submucous fibrosis (OSMF) and normal mucosa and compare the same.
    Methodology: A total number of 40 cases including different grades of dysplasia, OSMF and normal mucosa were immunohistochemically stained, location and intensity of its expression were evaluated for β-catenin. The results were statistically analyzed using the one-way analysis of variance and Chi-square test.
    Results: The expression of β-Catenin in the cytoplasm as well as in the nucleus increased from mild-to-moderate dysplasia to OSMF and to severe epithelial dysplasia in an increasing order. The expression is seen to translocate from membranous to cytoplasm to nucleus indicating a proliferative potential in these group of lesions.
    Conclusion: β-catenin is a promising marker which indicates the malignant transformation potential in the higher grades of dysplasia and OSMF.
    Language English
    Publishing date 2021-05-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2390999-7
    ISSN 1998-393X ; 0973-029X
    ISSN (online) 1998-393X
    ISSN 0973-029X
    DOI 10.4103/jomfp.JOMFP_41_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Diagnostic efficacy of neutrophil to lymphocyte ratio (NLR) in oral potentially malignant disorders and oral cancer.

    Singh, Shruti / Singh, Jaya / Ganguly, Roop / Chandra, Shaleen / Samadi, Fahad M / Suhail, Shaista

    Indian journal of pathology & microbiology

    2021  Volume 64, Issue 2, Page(s) 243–249

    Abstract: Background and aims: Inflammation is considered to be the seventh hallmark of cancer and plays a pivotal role in all stages of tumor development. Systemic inflammatory responses in particular neutrophil to lymphocyte ratio (NLR) have garnered immense ... ...

    Abstract Background and aims: Inflammation is considered to be the seventh hallmark of cancer and plays a pivotal role in all stages of tumor development. Systemic inflammatory responses in particular neutrophil to lymphocyte ratio (NLR) have garnered immense attention of current researchers and its role is well proven in various solid malignancies. Its prognostic role in oral cancer have been extensively studied. However, its diagnostic role is yet to be explored. The current study aims to investigate diagnostic utility of NLR in oral potentially malignant disorders and oral cancer, when compared to normal subjects.
    Methods: A total of 150 subjects were involved in the study, a total of 2.5 ml of blood was drawn from the median cubital vein of the patient in an EDTA vial and hematological parameters were assessed using Erba-Transasia B7256 Autoanalyzer and reassessed manually by two experts.
    Statistical analysis: The NLR values were recorded and tabulated as Mean ± S.D. and comparisons were analyzed using Kruskal Wallis and Mann Whitney post hoc U test. ROC curve analysis was performed to estimate cut-off values.
    Results: The NLR values when compared between the 3 groups were statistically significant (P < 0.001). The cut off value between disease and normal subject was 2.33, while the cut-off value between potentially malignant and malignant condition is 3.20.
    Conclusion: NLR can be a valuable diagnostic adjunct in oral cancer and potentially malignant disorders of oral cavity.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor ; Carcinoma, Squamous Cell/blood ; Carcinoma, Squamous Cell/diagnosis ; Female ; Humans ; Inflammation/pathology ; Lymphocyte Count ; Lymphocytes/cytology ; Male ; Middle Aged ; Mouth Neoplasms/blood ; Mouth Neoplasms/diagnosis ; Neutrophils/cytology ; Young Adult
    Chemical Substances Biomarkers, Tumor
    Language English
    Publishing date 2021-05-04
    Publishing country India
    Document type Journal Article
    ZDB-ID 197621-7
    ISSN 0974-5130 ; 0377-4929
    ISSN (online) 0974-5130
    ISSN 0377-4929
    DOI 10.4103/IJPM.IJPM_114_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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