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  1. Article ; Online: Gene regulation: Context is everything.

    Singh, Narendra P

    Current biology : CB

    2021  Volume 31, Issue 19, Page(s) R1115–R1117

    Abstract: How transcription factors regulate a distinct set of target genes in different cell types is a fundamental question. A new study demonstrates how Ultrabithorax, a Hox transcription factor, acts as both a repressor and an activator in a cell type-specific ...

    Abstract How transcription factors regulate a distinct set of target genes in different cell types is a fundamental question. A new study demonstrates how Ultrabithorax, a Hox transcription factor, acts as both a repressor and an activator in a cell type-specific manner to alter chromatin accessibility and gene regulation.
    MeSH term(s) Chromatin/genetics ; Drosophila Proteins/metabolism ; Gene Expression Regulation, Developmental ; Homeodomain Proteins/genetics ; Transcription Factors/genetics ; Transcription Factors/metabolism
    Chemical Substances Chromatin ; Drosophila Proteins ; Homeodomain Proteins ; Transcription Factors
    Language English
    Publishing date 2021-10-12
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1071731-6
    ISSN 1879-0445 ; 0960-9822
    ISSN (online) 1879-0445
    ISSN 0960-9822
    DOI 10.1016/j.cub.2021.08.064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3208: Show issues Location:
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  2. Article: Diversification and Functional Evolution of HOX Proteins.

    Singh, Narendra Pratap / Krumlauf, Robb

    Frontiers in cell and developmental biology

    2022  Volume 10, Page(s) 798812

    Abstract: Gene duplication and divergence is a major contributor to the generation of morphological diversity and the emergence of novel features in vertebrates during evolution. The availability of sequenced genomes has facilitated our understanding of the ... ...

    Abstract Gene duplication and divergence is a major contributor to the generation of morphological diversity and the emergence of novel features in vertebrates during evolution. The availability of sequenced genomes has facilitated our understanding of the evolution of genes and regulatory elements. However, progress in understanding conservation and divergence in the function of proteins has been slow and mainly assessed by comparing protein sequences in combination with
    Language English
    Publishing date 2022-05-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2022.798812
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  3. Article ; Online: A biochemical and morphological study with multiple linear regression modeling-based impact prediction of ambient air pollutants on some native tree species of Haldwani City of Kumaun Himalaya, Uttarakhand, India.

    Goswami, Meera / Kumar, Vinod / Singh, Narendra / Kumar, Pankaj

    Environmental science and pollution research international

    2023  Volume 30, Issue 30, Page(s) 74900–74915

    Abstract: The current study was conducted around the province of Haldwani City, Uttarakhand, India, to understand the seasonal variation of ambient air pollutants ( ... ...

    Abstract The current study was conducted around the province of Haldwani City, Uttarakhand, India, to understand the seasonal variation of ambient air pollutants (PM
    MeSH term(s) Air Pollutants/analysis ; Trees ; Environmental Pollutants/analysis ; Linear Models ; Nitrogen Dioxide/analysis ; Environmental Monitoring ; Air Pollution/analysis ; Dust/analysis ; Ascorbic Acid/analysis ; India ; Plant Leaves/chemistry
    Chemical Substances Air Pollutants ; Environmental Pollutants ; Nitrogen Dioxide (S7G510RUBH) ; Dust ; Ascorbic Acid (PQ6CK8PD0R)
    Language English
    Publishing date 2023-05-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-27563-4
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  4. Article: Agreement between Azithromycin and Erythromycin to Determine Inducible Clindamycin-Resistant Phenotypes in Staphylococcus aureus Isolates

    Goyal, Nisha / Singh, Narendra Pal

    Journal of Laboratory Physicians

    2023  

    Abstract: Objectives: To evaluate agreement in the detection of inducible clindamycin resistance by test method using azithromycin disk with reference method using erythromycin disk and to determine prevalence of inducible clindamycin-resistant phenotypes among ... ...

    Abstract Objectives: To evaluate agreement in the detection of inducible clindamycin resistance by test method using azithromycin disk with reference method using erythromycin disk and to determine prevalence of inducible clindamycin-resistant phenotypes among Staphylococcus aureus isolates.
    Materials and Methods: A total of 133 nonduplicate isolates of S. aureus from clinical samples were included in this prospective study. Agreement between erythromycin (reference method) and azithromycin (test method) disks for detection of inducible clindamycin resistance in S. aureus isolates was assessed.
    Statistical Analysis: Chi-square test was used for analyzing categorical variables ( p  < 0.05 was considered significant).
    Results: The prevalence of inducible clindamycin resistance (iMLSB) was 15.8%. A 100% agreement was recorded between reference and test methods for detecting inducible clindamycin-resistant phenotypes. For the determination of constitutive-resistant phenotypes (cMLSB) among S. aureus isolates, the test method demonstrated an agreement of 94.1%.
    Conclusion: The present study demonstrated an agreement in the identification of inducible clindamycin-resistant phenotypes among S. aureus isolates by both erythromycin and azithromycin disks.
    Keywords inducible clindamycin resistance ; iMLSB ; constitutive-resistant phenotypes ; cMLSB ; clindamycin ; azithromycin
    Language English
    Publishing date 2023-07-18
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2461120-7
    ISSN 0974-7826 ; 0974-2727 ; 0974-7826
    ISSN (online) 0974-7826
    ISSN 0974-2727 ; 0974-7826
    DOI 10.1055/s-0043-1771244
    Database Thieme publisher's database

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  5. Book: Manual of pediatric critical care

    Singh, Narendra C.

    1997  

    Title variant Pediatric critical care
    Author's details Narendra C. Singh
    Keywords Critical Care / in infancy & childhood / handbooks ; Critical Care / methods / handbooks ; Emergencies / in infancy & childhood / handbooks ; Emergency Medicine / methods / handbooks
    Language English
    Size XVIII, 430 S. : Ill., graph. Darst.
    Edition 1. print
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT007957921
    ISBN 0-7216-5949-7 ; 978-0-7216-5949-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1997 A 8613 order for loan Magazin

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  6. Article ; Online: Characterization of Chemotaxis-Associated Gene Dysregulation in Myeloid Cell Populations in the Lungs during Lipopolysaccharide-Mediated Acute Lung Injury.

    Holloman, Bryan Latrell / Cannon, Alkeiver / Wilson, Kiesha / Singh, Narendra / Nagarkatti, Mitzi / Nagarkatti, Prakash

    Journal of immunology (Baltimore, Md. : 1950)

    2024  Volume 210, Issue 12, Page(s) 2016–2028

    Abstract: During endotoxin-induced acute lung injury (ALI), immune cell recruitment resulting from chemotaxis is mediated by CXC and CC chemokines and their receptors. In this study, we investigated the role of chemokines and their receptors in the regulation of ... ...

    Abstract During endotoxin-induced acute lung injury (ALI), immune cell recruitment resulting from chemotaxis is mediated by CXC and CC chemokines and their receptors. In this study, we investigated the role of chemokines and their receptors in the regulation of myeloid cell populations in the circulation and the lungs of C57BL/6J mice exhibiting LPS-mediated ALI using single-cell RNA sequencing. During ALI, there was an increase in the myeloid cells, M1 macrophages, monocytes, neutrophils, and other granulocytes, whereas there was a decrease in the residential alveolar macrophages and M2 macrophages. Interestingly, LPS triggered the upregulation of CCL3, CCL4, CXCL2/3, and CXCL10 genes associated with cellular migration of various subsets of macrophages, neutrophils, and granulocytes. Furthermore, there was an increase in the frequency of myeloid cells expressing CCR1, CCR3, CCR5, and CXCR2 receptors during ALI. MicroRNA sequencing studies of vehicle versus LPS groups identified several dysregulated microRNAs targeting the upregulated chemokine genes. This study suggests that chemokine ligand-receptors interactions are responsible for myeloid cell heterogenicity and cellular recruitment to the lungs during ALI. The single-cell transcriptomics allowed for an in-depth assessment and characterization of myeloid cells involved in immune cell trafficking during ALI.
    MeSH term(s) Animals ; Mice ; Chemotaxis ; Lipopolysaccharides ; Mice, Inbred C57BL ; Lung ; Chemokines ; Acute Lung Injury/chemically induced ; Acute Lung Injury/genetics ; Myeloid Cells ; Receptors, Chemokine/genetics
    Chemical Substances Lipopolysaccharides ; Chemokines ; Receptors, Chemokine
    Language English
    Publishing date 2024-01-04
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 3056-9
    ISSN 1550-6606 ; 0022-1767 ; 1048-3233 ; 1047-7381
    ISSN (online) 1550-6606
    ISSN 0022-1767 ; 1048-3233 ; 1047-7381
    DOI 10.4049/jimmunol.2200822
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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.37: Show issues Location:
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  7. Article: Management of Root Rot (Rhizoctonia solani) of Mothbean through Bio-Agents

    Godara, S.L. / Singh, Narendra

    Legume research. 2021 Nov., v. 44, no. 11

    2021  

    Abstract: Root rot caused by Rhizoctonia solani is an important disease of mothbean, under severe infestation it causes 58–68% losses in grain yield. Three-year field experiments were conducted in hot arid conditions at Bikaner, Rajasthan during kharif seasons ... ...

    Abstract Root rot caused by Rhizoctonia solani is an important disease of mothbean, under severe infestation it causes 58–68% losses in grain yield. Three-year field experiments were conducted in hot arid conditions at Bikaner, Rajasthan during kharif seasons with the objective to find out suitable eco-friendly management strategies for root rot. The experiment was conducted on cv. RMO-225 with six different combination of Trichoderma harzianum + Pseudomonas fluorescens bio- agents viz, seed treatment, soil treatment and their combinations against the root rot disease and compared with an untreated control. Results of experiment showed that all the treatments brought significant decline in disease incidence and consequently enhancement of grain yield compared to control. The treatment having combination of Trichoderma harzianum + Pseudomonas fluorescens seed treatment (4+4 g/kg seed) + soil application of T. harzianum + P. fluorescens (1.25 +1.25 kg in 50 kg FYM for each/ha) had minimum (21.78%) root rot incidence, highest grain yield (10.56 q/ha) and net return (Rs. 14,338/ha). The T. harzianum seed treatment 8 g/kg seed + soil application of T. harzianum 2.5kg in 100 kg FYM/ha was the next best treatment with 25.56 per cent disease incidence and 9.42 q/ha of grain yield. These treatments can provide an effective, economical and eco-friendly management of root rot of mothbean for cultivators.
    Keywords Pseudomonas fluorescens ; Thanatephorus cucumeris ; Trichoderma harzianum ; disease incidence ; grain yield ; legumes ; research ; root rot ; seed treatment ; soil treatment ; India
    Language English
    Dates of publication 2021-11
    Size p. 1392-1397.
    Publishing place Agricultural Research Communication Centre
    Document type Article
    ISSN 0976-0571
    DOI 10.18805/LR-4242
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Management of black scurf (Rhizoctonia solani) of Potato through organic approaches

    Patel, Vikee M. / Singh, Narendra

    Indian journal of agricultural research. 2021 Apr., v. 55, no. 2

    2021  

    Abstract: Black scurf (Rhizoctonia solani) disease of potato is becoming prominent in many potato growing districts of Gujarat state which reduce quality and market value of the produce, resulting in economic losses. The field experiment was conducted during rabi ... ...

    Abstract Black scurf (Rhizoctonia solani) disease of potato is becoming prominent in many potato growing districts of Gujarat state which reduce quality and market value of the produce, resulting in economic losses. The field experiment was conducted during rabi season of 2014-15 in naturally infested field with scurf pathogen at Potato Research Station, S.D. Agricultural University, Deesa (Gujarat) with the objective to find out suitable management strategies for black scurf through organic approaches (bio-agents and organic amendments). Among different bio-agents (Trichoderma viride, T. harzianum. Pseudomonas fluorescens and Bacillus subtilis) tested against black scurf, the tuber treatment with 2 per cent boric acid spray along with tuber treatment with T. viride @ 10 g/kg seed before sowing recorded the lowest disease incidence (15.33%) and index (0.38) with highest total tuber yield (324.68 q/ha) with maximum income 2,57,414/ha. When price computed with healthy and diseased tuber yield among treatments, the maximum income variation was (92,986/ha) recorded by the same treatment followed by the tuber treatment with 3% boric acid spray before sowing (68,440/ ha). In case of various organic amendments tested, soil application of mustard cake @ 10 q/ha registered minimum disease incidence (37.33%) and disease index (0.66) as compared to rest of the organic treatment with highest total tuber yield (327.20 q/ha) with maximum income 2,65,010/ha. When price computed with healthy and diseased tuber yield among treatments, the maximum income variation was (1,12,990/ha) recorded by the same treatment followed by the neem cake @ 10 q/ha (56,660/ha). These organic treatments can provide an effective and economical management of black scurf of potato for cultivaters.
    Keywords Bacillus subtilis ; Pseudomonas fluorescens ; Thanatephorus cucumeris ; Trichoderma viride ; agricultural colleges ; agricultural research ; boric acid ; disease incidence ; field experimentation ; income ; market value ; mustard oil cake ; neem cake ; pathogens ; potatoes ; prices ; soil treatment ; India
    Language English
    Dates of publication 2021-04
    Size p. 157-162.
    Publishing place Agricultural Research Communication Centre
    Document type Article
    ZDB-ID 2569845-X
    ISSN 0976-058X ; 0367-8245
    ISSN (online) 0976-058X
    ISSN 0367-8245
    DOI 10.18805/IJARe.A-5465
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Editorial: Enhancing allele mining for crop improvement amid the emerging challenge of climate change.

    Tripodi, Pasquale / Singh, Narendra Kumar / Abberton, Michael / Nankar, Amol N

    Frontiers in plant science

    2023  Volume 14, Page(s) 1197086

    Language English
    Publishing date 2023-05-26
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2023.1197086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Magnetically recoverable Ni-doped iron oxide/graphitic carbon nitride nanocomposites for the improved photocatalytic degradation of ciprofloxacin: Investigation of degradation pathways.

    Naga Lakshmi, Chinthalapudi / Irfan, Mohammad / Sinha, Rahul / Singh, Narendra

    Environmental research

    2023  Volume 242, Page(s) 117812

    Abstract: Developing efficient and effective photocatalysts is essential for organic dyes and antibiotic degradation in wastewater. Ni-doped α- ... ...

    Abstract Developing efficient and effective photocatalysts is essential for organic dyes and antibiotic degradation in wastewater. Ni-doped α-Fe
    MeSH term(s) Ciprofloxacin/chemistry ; Wastewater ; Light ; Nanocomposites/chemistry ; Environmental Pollutants ; Ferric Compounds ; Graphite ; Nitrogen Compounds
    Chemical Substances Ciprofloxacin (5E8K9I0O4U) ; graphitic carbon nitride ; ferric oxide (1K09F3G675) ; Wastewater ; Environmental Pollutants ; Ferric Compounds ; Graphite (7782-42-5) ; Nitrogen Compounds
    Language English
    Publishing date 2023-12-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.117812
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 726: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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