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  1. Article: COVID-19: A Curious Abettor in the Occurrence of Stevens-Johnson Syndrome.

    Grover, Dheera / Singha, Meher / Parikh, Raj

    Cureus

    2022  Volume 14, Issue 3, Page(s) e23562

    Abstract: Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are immune-mediated life-threatening skin diseases. The condition is known to be caused by various infections, drugs (mainly antibiotics), or can be idiopathic. Amidst the novel ... ...

    Abstract Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are immune-mediated life-threatening skin diseases. The condition is known to be caused by various infections, drugs (mainly antibiotics), or can be idiopathic. Amidst the novel coronavirus 2019 (COVID-19) pandemic, there is an increasing number of SJS/TEN cases being reported. Viral infections are known to have decreased the threshold of drug reactions by inducing a pro-inflammatory state in the body. We report a case of TEN secondary to tamsulosin use in the setting of COVID-19 infection. There is only one documented case of tamsulosin-induced SJS, and no documented case of TEN secondary to tamsulosin use. Our patient was a 26-year-old male who presented to the hospital after a recent history of COVID-19 infection with a diffuse maculo-vesicular rash with bullae, involving the mucosa. The patient had recent use of tamsulosin on the day of presentation and there were bullae and erythematous rashes present in the oral mucosa as well as significant conjunctival erythema with pain on ocular movement on physical examination. His rash progressively worsened, involving greater than 30% of his body. A biopsy was done that showed full-thickness necrosis indicative of toxic epidermal necrolysis (TEN). We hypothesize that in our patient COVID-19 infections lowered the threshold for the development of SJS/TEN.
    Language English
    Publishing date 2022-03-28
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.23562
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Dangerous dog licks! - A rare case of epidural abscess secondary to

    Singha, Meher / Trejo Paredes, Camila / Alang, Neha / Wu, Ulysses

    IDCases

    2022  Volume 28, Page(s) e01483

    Abstract: We present a rare case of a 71-year-old female. She has a history of irritable bowel syndrome that is diet controlled. However she presented to the emergency department (ED) with a history of diarrhea, weakness, chills and right lower back pain for two ... ...

    Abstract We present a rare case of a 71-year-old female. She has a history of irritable bowel syndrome that is diet controlled. However she presented to the emergency department (ED) with a history of diarrhea, weakness, chills and right lower back pain for two days. She was found to have epidural abscesses secondary to
    Language English
    Publishing date 2022-03-29
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2022.e01483
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Clinico-Epidemiological Profile of Children Orphaned due to AIDS Residing in Care Giving Institutions in Coastal South India.

    Thapar, Rekha / Singha, Meher / Kumar, Nithin / Mithra, Prasanna / Unnikrishnan, Bhaskaran / Holla, Ramesh / Kulkarni, Vaman / Darshan, B B / Kumar, Avinash

    AIDS research and treatment

    2019  Volume 2019, Page(s) 4712908

    Abstract: Background: HIV/AIDS has a greater impact on children. Besides being orphaned by the untimely demise of one or both parents due to the disease, these children are more prone for discrimination by the society.: Methods: In this cross-sectional study ... ...

    Abstract Background: HIV/AIDS has a greater impact on children. Besides being orphaned by the untimely demise of one or both parents due to the disease, these children are more prone for discrimination by the society.
    Methods: In this cross-sectional study 86 children orphaned by AIDS residing in care giving institutions for HIV positive children in Mangalore were assessed for their clinico-epidemiological profile and nutritional status. Institutional Ethics Committee clearance was obtained before the commencement of the study. The collected data were analyzed using SPSS (Statistical Package for Social Sciences) version 11.5 and the results expressed in mean (standard deviation) and proportions. BMI was calculated and nutritional status assessed using WHO Z scores (BMI for Age) for children between 5 and 19 years separately for boys and girls.
    Results: The mean age of the children was 13.2 ± 3 years. Majority (
    Conclusion: From our study we draw conclusion that even though the children orphaned due to AIDS are rehabilitated in terms of having shelter and provision of education and health care, much needs to be done in terms of improving the nutritional status of these children and alleviating the discriminatory attitude of the society towards them.
    Language English
    Publishing date 2019-11-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2573930-X
    ISSN 2090-1259 ; 2090-1240
    ISSN (online) 2090-1259
    ISSN 2090-1240
    DOI 10.1155/2019/4712908
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Profile of cervical cancer patients attending Tertiary Care Hospitals of Mangalore, Karnataka: A 4 year retrospective study.

    Sharma, Aadhya / Kulkarni, Vaman / Bhaskaran, Unnikrishnan / Singha, Meher / Mujtahedi, Saad / Chatrath, Anshul / Sridhar, Mallika / Thapar, Rekha / Mithra, P Prasanna / Kumar, Nithin / Holla, Ramesh / Darshan, B B / Kumar, Avinash

    Journal of natural science, biology, and medicine

    2017  Volume 8, Issue 1, Page(s) 125–129

    Abstract: Objectives: To describe the sociodemographic characteristics and clinical profile of women presenting with cervical carcinoma and to identify factors associated with the timing of presentation and prognosis.: Materials and methods: A record-based ... ...

    Abstract Objectives: To describe the sociodemographic characteristics and clinical profile of women presenting with cervical carcinoma and to identify factors associated with the timing of presentation and prognosis.
    Materials and methods: A record-based descriptive study was carried out from 1
    Results: A total of 227 patients were included in the study. Mean (Standard Deviation) age of diagnosis of cervical cancer was found to be 55 ± 11 years. Majority of the women were Hindus (88.5%) and 51.0% of the women had occupational activities out of which manual labor was the most common. Forty-eight percent of the patients presented in the late stages. Squamous cell carcinoma was found to be the most common histological type. It was also observed that a slightly higher proportion of women with an age >49 years presented in late stages of the disease (
    Conclusions: Our study found out a higher proportion of late presentation by the patients. It emphasizes the need for the development and implementation of an efficient screening cum prevention program for cervical cancer and to continue active research in the domains of identifying all possible risk factors and steps to mitigate them.
    Language English
    Publishing date 2017-02-13
    Publishing country India
    Document type Journal Article
    ZDB-ID 2638867-4
    ISSN 2229-7707 ; 0976-9668
    ISSN (online) 2229-7707
    ISSN 0976-9668
    DOI 10.4103/0976-9668.198354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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