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  1. Book ; Online: A Polynomial Time, Pure Differentially Private Estimator for Binary Product Distributions

    Singhal, Vikrant

    2023  

    Abstract: We present the first $\varepsilon$-differentially private, computationally efficient algorithm that estimates the means of product distributions over $\{0,1\}^d$ accurately in total-variation distance, whilst attaining the optimal sample complexity to ... ...

    Abstract We present the first $\varepsilon$-differentially private, computationally efficient algorithm that estimates the means of product distributions over $\{0,1\}^d$ accurately in total-variation distance, whilst attaining the optimal sample complexity to within polylogarithmic factors. The prior work had either solved this problem efficiently and optimally under weaker notions of privacy, or had solved it optimally while having exponential running times.
    Keywords Computer Science - Data Structures and Algorithms ; Computer Science - Cryptography and Security ; Computer Science - Machine Learning ; Statistics - Machine Learning
    Publishing date 2023-04-13
    Publishing country us
    Document type Book ; Online
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  2. Article: Post-COVID-19 Vaccination and Thyrotoxicosis (ASIA Syndrome): Single-Centre Experience from India with Review of Literature.

    Singhal, Vaibhav / Gupta, Sushil

    Indian journal of endocrinology and metabolism

    2024  Volume 27, Issue 6, Page(s) 524–529

    Abstract: Introduction: Thyrotoxicosis is not uncommon after immunization. It is known as 'autoimmune/autoinflammatory syndrome by adjuvants (ASIA syndrome)' and is caused by immunological reaction to adjuvants. However, there is insufficient information on ... ...

    Abstract Introduction: Thyrotoxicosis is not uncommon after immunization. It is known as 'autoimmune/autoinflammatory syndrome by adjuvants (ASIA syndrome)' and is caused by immunological reaction to adjuvants. However, there is insufficient information on thyrotoxicosis after COVID-19 vaccination in the Indian subcontinent.
    Aims/objectives: To investigate the spectrum of thyrotoxicosis after COVID-19 immunization.
    Settings and design: A single-centre retrospective study was conducted at a tertiary care academic institute in India.
    Materials and methods: We studied the clinical symptoms, biochemical markers, imaging characteristics and treatment of every patient who was diagnosed with thyrotoxicosis within 60 days of receiving the COVID-19 vaccine.
    Results: Following COVID-19 vaccination, we diagnosed ten people (mean age 39.9 years, range 22-63 years) with thyrotoxicosis [Graves' disease (GD,
    Conclusions: SAT, GD and GO may occur as a manifestation of ASIA syndrome, following immunization with COVISHIELD™ and COVAXIN
    Language English
    Publishing date 2024-01-11
    Publishing country India
    Document type Journal Article
    ZDB-ID 2600211-5
    ISSN 2230-9500 ; 2230-8210
    ISSN (online) 2230-9500
    ISSN 2230-8210
    DOI 10.4103/ijem.ijem_202_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Peritoneal flap technique for abdominal wall expansion in the management of complex ventral hernias: a multicentre study from India.

    Baig, S J / Singhal, V / Afaque, Md Y / Kakadiy, C / Varma, A

    Hernia : the journal of hernias and abdominal wall surgery

    2024  

    Abstract: Introduction: Large abdominal wall hernias often require techniques for wall expansion to improve surgical outcomes. The peritoneal flap hernioplasty (PF) is one such technique that utilizes the hernia sac to reconstruct the abdominal wall, however, ... ...

    Abstract Introduction: Large abdominal wall hernias often require techniques for wall expansion to improve surgical outcomes. The peritoneal flap hernioplasty (PF) is one such technique that utilizes the hernia sac to reconstruct the abdominal wall, however, with limited published data. It is a modification of the Rives-Stoppa mesh repair where a part of the bisected hernia sac is utilized to reconstruct the anterior fascia and the other part for the posterior fascia. We present a collated retrospective analysis of the outcomes from three centers performing PF with or without transverse abdominis release (TAR) in patients with complex ventral hernias.
    Methods: The PF was performed in patients with incisional hernias, both midline and lateral. The primary outcome measured was hernia recurrence. The secondary outcomes were to evaluate pain, surgical site infection, seroma, hematoma, wound dehiscence, pseudo-recurrence, Clavien-Dindo score for complications, and the patient's reported quality of life. The quality of life was assessed by oral questionnaires in the follow-up period.
    Results: We analyzed 63 patients (38 female, 25 male) with a mean width of hernia defect of 11 cm SD 4. Based on the European Hernia Society (EHS) classification 42 patients were W3 and 21 were W2 hernias. Fifty patients had a midline hernia, while the rest of the patients included transverse, subcostal, and rooftop incision hernias. The classical peritoneal flap procedure was done in 29 (46%) patients, while the peritoneal flap with TAR was done in 34 (54%) patients. Four patients had symptomatic seroma (6%), seven superficial surgical site infection (SSI) (11%), one deep SSI (1.5%), one skin necrosis (1.5%), and one anterior peritoneal flap necrosis (1.5%). No patient required postoperative ventilatory support. The mean pain score on day one was 3/10. There was no recurrence in the mean follow-up of 17 months (range 5 to 49 months). Overall, 58 of 63 (92%) patients reported being satisfied with their surgery.
    Conclusion: In our multicentre study, we found the PF technique with or without TAR for midline and non-midline ventral hernia leads to satisfactory outcomes in terms of low recurrence, low rate of complications, and a good quality of life in the medium to long term. It appears to be a useful technique in the surgeon's armamentarium to repair W2 and W3 hernias needing expansion of abdominal domain.
    Language English
    Publishing date 2024-04-03
    Publishing country France
    Document type Journal Article
    ZDB-ID 1388125-5
    ISSN 1248-9204 ; 1265-4906
    ISSN (online) 1248-9204
    ISSN 1265-4906
    DOI 10.1007/s10029-024-02993-2
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5390: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Readiness of the Stroke Treatment in India: Still an Uphill Task!

    Singhal, Vasudha / Prabhakar, Hemanshu

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2023  Volume 27, Issue 9, Page(s) 607–608

    Abstract: How to cite this ... ...

    Abstract How to cite this article
    Language English
    Publishing date 2023-09-14
    Publishing country India
    Document type Editorial
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-24525
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  5. Article ; Online: Metabolic health tracking using Ultrahuman M1 continuous glucose monitoring platform in non- and pre-diabetic Indians: a multi-armed observational study.

    Chaudhry, Monik / Kumar, Mohit / Singhal, Vatsal / Srinivasan, Bhuvan

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 6490

    Abstract: Continuous glucose monitoring (CGM) device adoption in non- and pre-diabetics for preventive healthcare has uncovered a paucity of benchmarking data on glycemic control and insulin resistance for the high-risk Indian/South Asian demographic. Furthermore, ...

    Abstract Continuous glucose monitoring (CGM) device adoption in non- and pre-diabetics for preventive healthcare has uncovered a paucity of benchmarking data on glycemic control and insulin resistance for the high-risk Indian/South Asian demographic. Furthermore, the correlational efficacy between digital applications-derived health scores and glycemic indices lacks clear supportive evidence. In this study, we acquired glycemic variability (GV) using the Ultrahuman (UH) M1 CGM, and activity metrics via the Fitbit wearable for Indians/South Asians with normal glucose control (non-diabetics) and those with pre-diabetes (N = 53 non-diabetics, 52 pre-diabetics) for 14 days. We examined whether CGM metrics could differentiate between the two groups, assessed the relationship of the UH metabolic score (MetSc) with clinical biomarkers of dysglycemia (OGTT, HbA1c) and insulin resistance (HOMA-IR); and tested which GV metrics maximally correlated with inflammation (Hs-CRP), stress (cortisol), sleep, step count and heart rate. We found significant inter-group differences for mean glucose levels, restricted time in range (70-110 mg/dL), and GV-by-SD, all of which improved across days. Inflammation was strongly linked with specific GV metrics in pre-diabetics, while sleep and activity correlated modestly in non-diabetics. Finally, MetSc displayed strong inverse relationships with insulin resistance and dysglycemia markers. These findings present initial guidance GV data of non- and pre-diabetic Indians and indicate that digitally-derived metabolic scores can positively influence glucose management.
    MeSH term(s) Humans ; Prediabetic State/diagnosis ; Blood Glucose/metabolism ; Insulin Resistance ; Blood Glucose Self-Monitoring ; Continuous Glucose Monitoring ; Inflammation ; Glucose
    Chemical Substances Blood Glucose ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2024-03-18
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-56933-2
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  6. Article: Upper extremity mass with lipomatous axillary involvement and multiple level encasement of the brachial plexus.

    Moorefield, Amanda K / Singhal, Virender

    Radiology case reports

    2022  Volume 17, Issue 12, Page(s) 4893–4898

    Abstract: A 40-year-old female presented for surgical consultation of an upper extremity soft tissue mass. Initial ultrasound report recorded a 5.5 cm mass, consistent with a subcutaneous lipoma. Intra-operative visualization revealed an intramuscular lipoma ... ...

    Abstract A 40-year-old female presented for surgical consultation of an upper extremity soft tissue mass. Initial ultrasound report recorded a 5.5 cm mass, consistent with a subcutaneous lipoma. Intra-operative visualization revealed an intramuscular lipoma emerging from brachialis muscle. Post-excision MRI was ordered for continued axillary fullness which revealed lipomatous extension into axilla and posterior arm with multiple level encasement of the brachial plexus. Lipomas with brachial plexus involvement are rare and can present with a range of symptoms and distortion of local anatomy. Surgical debulking is challenging requiring microsurgical expertise for adequate removal and to minimize long-term neurological deficits.
    Language English
    Publishing date 2022-10-17
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2022.08.100
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  7. Book ; Online: Not All Learnable Distribution Classes are Privately Learnable

    Bun, Mark / Kamath, Gautam / Mouzakis, Argyris / Singhal, Vikrant

    2024  

    Abstract: We give an example of a class of distributions that is learnable in total variation distance with a finite number of samples, but not learnable under $(\varepsilon, \delta)$-differential privacy. This refutes a conjecture of Ashtiani. ... Comment: To ... ...

    Abstract We give an example of a class of distributions that is learnable in total variation distance with a finite number of samples, but not learnable under $(\varepsilon, \delta)$-differential privacy. This refutes a conjecture of Ashtiani.

    Comment: To appear in ALT 2024
    Keywords Computer Science - Data Structures and Algorithms ; Computer Science - Cryptography and Security ; Statistics - Machine Learning
    Publishing date 2024-01-31
    Publishing country us
    Document type Book ; Online
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  8. Article ; Online: Trajectory of Gonadal Hormones in Adolescent Males up to 2 Years After Sleeve Gastrectomy.

    Kaur, Snimarjot / Bredella, Miriam A / Misra, Madhusmita / Singhal, Vibha

    Obesity surgery

    2023  Volume 33, Issue 10, Page(s) 3323–3326

    Abstract: Sleeve gastrectomy (SG) has many metabolic benefits and leads to improvements in testosterone levels, which means improvement in the Leydig cell function of the testis. However, data about the effects of SG on Sertoli cell function (as assessed by ... ...

    Abstract Sleeve gastrectomy (SG) has many metabolic benefits and leads to improvements in testosterone levels, which means improvement in the Leydig cell function of the testis. However, data about the effects of SG on Sertoli cell function (as assessed by inhibin B) are not available. In this preliminary study, we evaluate, for the first time, the effect of SG in adolescents after SG. We evaluate 16 adolescent and young adult males, six of whom underwent SG and followed them for 2 years. We report that Leydig cell function (as assessed by testosterone levels) improved and was associated with degree of weight loss. Sertoli cell function improved only slightly in SG group and did not change compared to the nonsurgical controls, and these changes were not associated with degree of weight loss. Thus, we conclude that larger and long-term follow-up studies are required to evaluate the changes in Sertoli cell function after SG as that is integral to male fertility.Clinical Trial Registration: NCT02557438.
    MeSH term(s) Adolescent ; Humans ; Male ; Young Adult ; Gastrectomy ; Gastric Bypass ; Gonadal Hormones ; Obesity, Morbid/surgery ; Testosterone ; Weight Loss/physiology
    Chemical Substances Gonadal Hormones ; Testosterone (3XMK78S47O)
    Language English
    Publishing date 2023-08-10
    Publishing country United States
    Document type Clinical Study ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-023-06759-0
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3381: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Clinical Approach to Acute Decline in Sensorium.

    Singhal, Vasudha

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2015  Volume 23, Issue Suppl 2, Page(s) S120–S123

    Abstract: How to cite this article: ...

    Abstract How to cite this article:
    Language English
    Publishing date 2015-02-20
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-23188
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  10. Book: Handbook of Indian agriculture

    Singhal, Vikas

    1995  

    Author's details Vikas Singhal
    Language English
    Size 511 S.
    Publisher Vikas Publ. House
    Publishing place New Delhi
    Publishing country India
    Document type Book
    HBZ-ID HT007196358
    ISBN 0706997624 ; 9780706997620
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    964/828 available for loan (reading room) Freihandmagazin (U1)

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