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  1. Article ; Online: Enterococcal meningitis associated with

    Cosimi, Lavinia / Di Bella, Stefano / Luzzati, Roberto / Simeth, Catrin Theresia / Pinamonti, Maurizio / Cominotto, Franco / Sisto, Ugo Giulio

    Le infezioni in medicina

    2023  Volume 31, Issue 4, Page(s) 583–590

    Abstract: Strongyloides ... ...

    Abstract Strongyloides stercoralis
    Language English
    Publishing date 2023-12-01
    Publishing country Italy
    Document type Case Reports
    ZDB-ID 2041081-5
    ISSN 2532-8689 ; 1124-9390
    ISSN (online) 2532-8689
    ISSN 1124-9390
    DOI 10.53854/liim-3104-18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Epidemiology and management of transient ischemic attack in Trieste district, how day hospital assessment improves outcomes: a five-year retrospective study.

    Caruso, Paola / Prandin, Gabriele / Rossi, Lucrezia / Cegalin, Matteo / Lugnan, Carlo / Pasquin, Fulvio / Sisto, Ugo Giulio / Furlanis, Giovanni / Naccarato, Marcello / Cominotto, Franco / Manganotti, Paolo

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2024  

    Abstract: Background: Transient ischemic attack (TIA) is defined as a transient episode of neurologic dysfunction, without acute infarction or tissue injury lasting less than 24 h. Previous data suggest TIA precedes 15% of ischemic strokes, with a higher risk in ... ...

    Abstract Background: Transient ischemic attack (TIA) is defined as a transient episode of neurologic dysfunction, without acute infarction or tissue injury lasting less than 24 h. Previous data suggest TIA precedes 15% of ischemic strokes, with a higher risk in the first week. Current practice guidelines advise evaluation through rapid neurological visit or admission to hospital. We provide data on TIA incidence in Trieste, and we compare three different types of assessment: day hospital (DH), stroke unit (SU), and emergency department/outpatients (ED).
    Methods: This is a 5-year retrospective study of transient cerebrovascular events admitted in the University Hospital of Trieste (230.623 inhabitants), between 2016 and 2020. We calculated TIA prevalence in Trieste district's general population. Our primary endpoint is ischemic recurrences within 90 days, and we evaluate the possible association between different types of management.
    Results: TIA incidence rate was 0.54/1000 inhabitants. In the multivariate analysis remained significantly associated with primary endpoint: ABCD2 (OR 1.625, CI 95% 1.114-2.369, p = 0.012) and DH evaluation (OR 0.260, CI 95% 0.082-0.819, p = 0.021).
    Conclusions: Incidence of TIA in Trieste district is in line with previous data. We demonstrate the crucial role of DH evaluation over the outpatient/ED in reducing overall mortality and recurrence rate. Prompt recognition of patients at high risk for cerebrovascular events and specialist follow-up may reduce the incidence of major vascular events and death.
    Language English
    Publishing date 2024-03-11
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-024-07443-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Correction to: Epidemiology and management of transient ischemic attack in Trieste district, how day hospital assessment improves outcomes: a five‑year retrospective study.

    Caruso, Paola / Prandin, Gabriele / Rossi, Lucrezia / Cegalin, Matteo / Lugnan, Carlo / Pasquin, Fulvio / Sisto, Ugo Giulio / Furlanis, Giovanni / Naccarato, Marcello / Cominotto, Franco / Manganotti, Paolo

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2024  

    Language English
    Publishing date 2024-03-23
    Publishing country Italy
    Document type Published Erratum
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-024-07482-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Lung ultrasound in ruling out COVID-19 pneumonia in the ED: a multicentre prospective sensitivity study.

    Di Gioia, Carmine Cristiano / Artusi, Nicola / Xotta, Giovanni / Bonsano, Marco / Sisto, Ugo Giulio / Tecchiolli, Marzia / Orso, Daniele / Cominotto, Franco / Amore, Giulia / Meduri, Stefano / Copetti, Roberto

    Emergency medicine journal : EMJ

    2021  Volume 39, Issue 3, Page(s) 199–205

    Abstract: Purpose: Early diagnosis of COVID-19 has a crucial role in confining the spread among the population. Lung ultrasound (LUS) was included in the diagnostic pathway for its high sensitivity, low costs, non-invasiveness and safety. We aimed to test the ... ...

    Abstract Purpose: Early diagnosis of COVID-19 has a crucial role in confining the spread among the population. Lung ultrasound (LUS) was included in the diagnostic pathway for its high sensitivity, low costs, non-invasiveness and safety. We aimed to test the sensitivity of LUS to rule out COVID-19 pneumonia (COVIDp) in a population of patients with suggestive symptoms.
    Methods: Multicentre prospective observational study in three EDs in Northeastern Italy during the first COVID-19 outbreak. A convenience sample of 235 patients admitted to the ED for symptoms suggestive COVIDp (fever, cough or shortness of breath) from 17 March 2020 to 26 April 2020 was enrolled. All patients underwent a sequential assessment involving: clinical examination, LUS, CXR and arterial blood gas. The index test under investigation was a standardised protocol of LUS compared with a pragmatic composite reference standard constituted by: clinical gestalt, real-time PCR test, radiological and blood gas results. Of the 235 enrolled patients, 90 were diagnosed with COVIDp according to the reference standard.
    Results: Among the patients with suspected COVIDp, the prevalence of SARS-CoV-2 was 38.3%. The sensitivity of LUS for diagnosing COVIDp was 85.6% (95% CI 76.6% to 92.1%); the specificity was 91.7% (95% CI 86.0% to 95.7%). The positive predictive value and the negative predictive value were 86.5% (95%CI 78.8% to 91.7%) and 91.1% (95% CI 86.1% to 94.4%) respectively. The diagnostic accuracy of LUS for COVIDp was 89.4% (95% CI 84.7% to 93.0%). The positive likelihood ratio was 10.3 (95% CI 6.0 to 17.9), and the negative likelihood ratio was 0.16 (95% CI 0.1 to 0.3).
    Conclusion: In a population with high SARS-CoV-2 prevalence, LUS has a high sensitivity (and negative predictive value) enough to rule out COVIDp in patients with suggestive symptoms. The role of LUS in diagnosing patients with COVIDp is perhaps even more promising. Nevertheless, further research with adequately powered studies is needed.
    Trial registration number: NCT04370275.
    MeSH term(s) COVID-19 ; Humans ; Lung/diagnostic imaging ; Pneumonia/diagnosis ; Prospective Studies ; SARS-CoV-2 ; Ultrasonography/methods
    Language English
    Publishing date 2021-12-22
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Observational Study
    ZDB-ID 2040124-3
    ISSN 1472-0213 ; 1472-0205
    ISSN (online) 1472-0213
    ISSN 1472-0205
    DOI 10.1136/emermed-2020-210973
    Database MEDical Literature Analysis and Retrieval System OnLINE

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